{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:06:39Z","timestamp":1790802399273,"version":"4.1.0"},"reference-count":81,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.celrep.2024.114750","type":"journal-article","created":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T05:46:30Z","timestamp":1726379190000},"page":"114750","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice"],"prefix":"10.1016","volume":"43","author":[{"given":"Ionel","family":"Sandovici","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denise S.","family":"Fernandez-Twinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niamh","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy N.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoichi","family":"Sekita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilona","family":"Zvetkova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Ferland-McCollough","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haydn M.","family":"Prosser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lila M.","family":"Oyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas C.","family":"Pantale\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo","family":"Cimadomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina","family":"Barbosa de Queiroz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia S.K.","family":"Cheuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola M.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard G.","family":"Kay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Antrobus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Hoelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcella K.L.","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noel H.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan H.","family":"Geyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas F.","family":"Reissig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang J.","family":"Weninger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Siddle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne E.","family":"Willis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian Y.H.","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Bushell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E.","family":"Ozanne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8976-1679","authenticated-orcid":false,"given":"Miguel","family":"Const\u00e2ncia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2024.114750_bib1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2024.114750_bib2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/s41580-018-0059-1","article-title":"Regulation of microRNA biogenesis and its crosstalk with other cellular pathways","volume":"20","author":"Treiber","year":"2019","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.celrep.2024.114750_bib3","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3389\/fendo.2018.00402","article-title":"Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation","volume":"9","author":"O'Brien","year":"2018","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.celrep.2024.114750_bib4","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1038\/nrg3198","article-title":"MicroRNA profiling: approaches and considerations","volume":"13","author":"Pritchard","year":"2012","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.celrep.2024.114750_bib5","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3390\/cells9020276","article-title":"miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis","volume":"9","author":"Condrat","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.celrep.2024.114750_bib6","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nrd.2016.117","article-title":"Non-coding RNAs as drug targets","volume":"16","author":"Matsui","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.celrep.2024.114750_bib7","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/j.cell.2019.01.043","article-title":"Genomic Imprinting and Physiological Processes in Mammals","volume":"176","author":"Tucci","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2024.114750_bib8","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1002\/bies.201100032","article-title":"Do repeated arrays of regulatory small-RNA genes elicit genomic imprinting?: Concurrent emergence of large clusters of small non-coding RNAs and genomic imprinting at four evolutionarily distinct eutherian chromosomal loci","volume":"33","author":"Labialle","year":"2011","journal-title":"Bioessays"},{"key":"10.1016\/j.celrep.2024.114750_bib9","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.4161\/epi.22884","article-title":"Small regulatory RNAs controlled by genomic imprinting and their contribution to human disease","volume":"7","author":"Girardot","year":"2012","journal-title":"Epigenetics"},{"key":"10.1016\/j.celrep.2024.114750_bib10","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.3390\/genes11091038","article-title":"The Evolution of Imprinted microRNAs and Their RNA Targets","volume":"11","author":"Haig","year":"2020","journal-title":"Genes"},{"key":"10.1016\/j.celrep.2024.114750_bib11","doi-asserted-by":"crossref","first-page":"706","DOI":"10.3389\/fgene.2018.00706","article-title":"Imprinted MicroRNA Gene Clusters in the Evolution, Development, and Functions of Mammalian Placenta","volume":"9","author":"Malnou","year":"2018","journal-title":"Front. Genet."},{"key":"10.1016\/j.celrep.2024.114750_bib12","doi-asserted-by":"crossref","first-page":"4219","DOI":"10.3390\/ijms20174219","article-title":"Molecular and Clinical Opposite Findings in 11p15.5 Associated Imprinting Disorders: Characterization of Basic Mechanisms to Improve Clinical Management","volume":"20","author":"Wesseler","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.celrep.2024.114750_bib13","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1159\/000343995","article-title":"Insulin-like growth factor 2 in development and disease: a mini-review","volume":"59","author":"Bergman","year":"2013","journal-title":"Gerontology"},{"key":"10.1016\/j.celrep.2024.114750_bib14","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2019103777","article-title":"A guide to naming human non-coding RNA genes","volume":"39","author":"Seal","year":"2020","journal-title":"EMBO J."},{"key":"10.1016\/j.celrep.2024.114750_bib15","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a002592","article-title":"Mammalian genomic imprinting","volume":"3","author":"Bartolomei","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.celrep.2024.114750_bib16","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/ncb2521","article-title":"The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r","volume":"14","author":"Keniry","year":"2012","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.celrep.2024.114750_bib17","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1158\/0008-5472.CAN-09-4456","article-title":"Oncogenic role of miR-483-3p at the IGF2\/483 locus","volume":"70","author":"Veronese","year":"2010","journal-title":"Cancer Res."},{"key":"10.1016\/j.celrep.2024.114750_bib18","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1101\/gad.224170.113","article-title":"The IGF2 intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis","volume":"27","author":"Liu","year":"2013","journal-title":"Genes Dev."},{"key":"10.1016\/j.celrep.2024.114750_bib19","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/j.febslet.2012.03.035","article-title":"MiR-483-5p suppresses the proliferation of glioma cells via directly targeting ERK1","volume":"586","author":"Wang","year":"2012","journal-title":"FEBS Lett."},{"key":"10.1016\/j.celrep.2024.114750_bib20","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.cell.2014.12.018","article-title":"Extracellular metabolic energetics can promote cancer progression","volume":"160","author":"Loo","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2024.114750_bib21","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1038\/cdd.2011.183","article-title":"Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes","volume":"19","author":"Ferland-McCollough","year":"2012","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.celrep.2024.114750_bib22","doi-asserted-by":"crossref","first-page":"3092","DOI":"10.1096\/fj.10-168401","article-title":"miR-483-3p controls proliferation in wounded epithelial cells","volume":"25","author":"Bertero","year":"2011","journal-title":"Faseb. J."},{"key":"10.1016\/j.celrep.2024.114750_bib23","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.bbrc.2016.06.051","article-title":"miR-483-3p regulates hyperglycaemia-induced cardiomyocyte apoptosis in transgenic mice","volume":"477","author":"Qiao","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.celrep.2024.114750_bib24","doi-asserted-by":"crossref","first-page":"25312","DOI":"10.1074\/jbc.M112.356733","article-title":"MicroRNAs in the pineal gland: miR-483 regulates melatonin synthesis by targeting arylalkylamine N-acetyltransferase","volume":"287","author":"Clokie","year":"2012","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2024.114750_bib25","doi-asserted-by":"crossref","first-page":"19955","DOI":"10.1074\/jbc.M115.650705","article-title":"Differentially Expressed MicroRNA-483 Confers Distinct Functions in Pancreatic \u03b2- and \u03b1-Cells","volume":"290","author":"Mohan","year":"2015","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.celrep.2024.114750_bib26","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqab031","article-title":"microRNA-483 Protects\u00a0Pancreatic \u03b2-Cells by Targeting ALDH1A3","volume":"162","author":"Wang","year":"2021","journal-title":"Endocrinology"},{"key":"10.1016\/j.celrep.2024.114750_bib27","doi-asserted-by":"crossref","first-page":"349","DOI":"10.2337\/db18-0084","article-title":"Increased Expression of miR-483-3p Impairs the Vascular Response to Injury in Type 2 Diabetes","volume":"68","author":"Kuschnerus","year":"2019","journal-title":"Diabetes"},{"key":"10.1016\/j.celrep.2024.114750_bib28","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1186\/1471-2164-10-478","article-title":"Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring","volume":"10","author":"Zhang","year":"2009","journal-title":"BMC Genom."},{"key":"10.1016\/j.celrep.2024.114750_bib29","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1002\/bit.25853","article-title":"Temperature-sensitive miR-483 is a conserved regulator of recombinant protein and viral vector production in mammalian cells","volume":"113","author":"Emmerling","year":"2016","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.celrep.2024.114750_bib30","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/375034a0","article-title":"Disruption of imprinting caused by deletion of the H19\u00a0gene region in mice","volume":"375","author":"Leighton","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2024.114750_bib31","doi-asserted-by":"crossref","first-page":"4840","DOI":"10.1073\/pnas.1101734108","article-title":"Mutated beta-catenin evades a microRNA-dependent regulatory loop","volume":"108","author":"Veronese","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2024.114750_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2022.104020","article-title":"Transcriptome and fatty-acid signatures of adipocyte hypertrophy and its non-invasive MR-based characterization in human adipose tissue","volume":"79","author":"Honecker","year":"2022","journal-title":"EBioMedicine"},{"key":"10.1016\/j.celrep.2024.114750_bib33","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1101\/gad.14.8.963","article-title":"Leptin-specific patterns of gene expression in white adipose tissue","volume":"14","author":"Soukas","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.celrep.2024.114750_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1009069","article-title":"Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function","volume":"16","author":"Hammerle","year":"2020","journal-title":"PLoS Genet."},{"key":"10.1016\/j.celrep.2024.114750_bib35","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1093\/embo-reports\/kve248","article-title":"An intragenic methylated region in the imprinted Igf2 gene augments transcription","volume":"2","author":"Murrell","year":"2001","journal-title":"EMBO Rep."},{"key":"10.1016\/j.celrep.2024.114750_bib36","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1007\/s004670000351","article-title":"Role of insulin receptors and IGF receptors in growth and development","volume":"14","author":"Rother","year":"2000","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.celrep.2024.114750_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2021.101245","article-title":"Insulin-like growth factors: Ligands, binding proteins, and receptors","volume":"52","author":"LeRoith","year":"2021","journal-title":"Mol. Metabol."},{"key":"10.1016\/j.celrep.2024.114750_bib38","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.3390\/cells11121886","article-title":"IGF2: Development, Genetic and Epigenetic Abnormalities","volume":"11","author":"S\u00e9l\u00e9nou","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.celrep.2024.114750_bib39","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1111\/jog.14412","article-title":"miR-483 is downregulated in pre-eclampsia via targeting insulin-like growth factor 1 (IGF1) and regulates the PI3K\/Akt\/mTOR pathway of endothelial progenitor cells","volume":"47","author":"Han","year":"2021","journal-title":"J.\u00a0Obstet. Gynaecol. Res."},{"key":"10.1016\/j.celrep.2024.114750_bib40","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1038\/ncomms2484","article-title":"IGF-1 promotes the development and cytotoxic activity of human NK cells","volume":"4","author":"Ni","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2024.114750_bib41","doi-asserted-by":"crossref","first-page":"9839","DOI":"10.1002\/jcp.27672","article-title":"miR-483 inhibits bovine myoblast cell proliferation and differentiation via IGF1\/PI3K\/AKT signal pathway","volume":"234","author":"Song","year":"2019","journal-title":"J.\u00a0Cell. Physiol."},{"key":"10.1016\/j.celrep.2024.114750_bib42","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0092-8674(05)80085-6","article-title":"Role of insulin-like growth factors in embryonic and postnatal growth","volume":"75","author":"Baker","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2024.114750_bib43","doi-asserted-by":"crossref","first-page":"5057","DOI":"10.1113\/JP273330","article-title":"Placental phenotype and the insulin-like growth factors: resource allocation to fetal growth","volume":"595","author":"Sferruzzi-Perri","year":"2017","journal-title":"J.\u00a0Physiol."},{"key":"10.1016\/j.celrep.2024.114750_bib44","doi-asserted-by":"crossref","first-page":"2483","DOI":"10.2337\/diabetes.52.10.2483","article-title":"Insulin resistance in the liver-specific IGF-1 gene-deleted mouse is abrogated by deletion of the acid-labile subunit of the IGF-binding protein-3 complex: relative roles of growth hormone and IGF-1 in insulin resistance","volume":"52","author":"Haluzik","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.celrep.2024.114750_bib45","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/23060","article-title":"IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1","volume":"400","author":"Musar\u00f2","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2024.114750_bib46","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.3390\/cells9091970","article-title":"Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy","volume":"9","author":"Yoshida","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.celrep.2024.114750_bib47","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/0006-291X(86)91246-5","article-title":"Characterization of the insulin and insulin-like growth factor receptors and responsitivity of a fibroblast\/adipocyte cell line before and after differentiation","volume":"137","author":"Shimizu","year":"1986","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.celrep.2024.114750_bib48","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.2337\/db16-0212","article-title":"Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function","volume":"65","author":"Boucher","year":"2016","journal-title":"Diabetes"},{"key":"10.1016\/j.celrep.2024.114750_bib49","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s12872-021-01964-0","article-title":"Replication study reveals miR-483-5p as an important target in prevention of cardiometabolic disease","volume":"21","author":"Gallo","year":"2021","journal-title":"BMC Cardiovasc. Disord."},{"key":"10.1016\/j.celrep.2024.114750_bib50","first-page":"37","article-title":"Impacts of MicroRNA-483 on Human Diseases","volume":"9","author":"Matson","year":"2023","journal-title":"Noncoding. RNA"},{"key":"10.1016\/j.celrep.2024.114750_bib51","doi-asserted-by":"crossref","first-page":"e215","DOI":"10.1371\/journal.pgen.0030215","article-title":"Most Caenorhabditis elegans microRNAs are individually not essential for development or viability","volume":"3","author":"Miska","year":"2007","journal-title":"PLoS Genet."},{"key":"10.1016\/j.celrep.2024.114750_bib52","doi-asserted-by":"crossref","first-page":"R169","DOI":"10.1093\/hmg\/ddq367","article-title":"Analysis of microRNA knockouts in mice","volume":"19","author":"Park","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2024.114750_bib53","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.celrep.2012.02.008","article-title":"A resource for the conditional ablation of microRNAs in the mouse","volume":"1","author":"Park","year":"2012","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2024.114750_bib54","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/s41419-019-1423-6","article-title":"H19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis","volume":"10","author":"Zhang","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.celrep.2024.114750_bib55","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-98777-0","article-title":"ZBED6 regulates Igf2 expression partially through its regulation of miR483 expression","volume":"11","author":"Naboulsi","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2024.114750_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2021.103208","article-title":"MicroRNA function can be reversed by altering target gene expression levels","volume":"24","author":"Svoronos","year":"2021","journal-title":"iScience"},{"key":"10.1016\/j.celrep.2024.114750_bib57","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.ghir.2014.06.005","article-title":"IGF-I sensitivity in Silver-Russell syndrome with IGF2\/H19 hypomethylation","volume":"24","author":"Iliev","year":"2014","journal-title":"Growth Hormone IGF Res."},{"key":"10.1016\/j.celrep.2024.114750_bib58","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1080\/15592294.2019.1615357","article-title":"Altered microRNA expression profiles in large offspring syndrome and Beckwith-Wiedemann syndrome","volume":"14","author":"Li","year":"2019","journal-title":"Epigenetics"},{"key":"10.1016\/j.celrep.2024.114750_bib59","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.biocel.2016.09.022","article-title":"miR-483 is a self-regulating microRNA and can activate its own expression via USF1 in HeLa cells","volume":"80","author":"Emmerling","year":"2016","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.celrep.2024.114750_bib60","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1038\/s41467-023-37688-2","article-title":"miR-483-5p offsets functional and behavioural effects of stress in male mice through synapse-targeted repression of Pgap2 in the basolateral amygdala","volume":"14","author":"Mucha","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2024.114750_bib61","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1111\/jcmm.12293","article-title":"Overexpression of miR-483-5p\/3p cooperate to inhibit mouse liver fibrosis by suppressing the TGF-b stimulated HSCs in transgenic mice","volume":"18","author":"Li","year":"2014","journal-title":"J.\u00a0Cell Mol. Med."},{"key":"10.1016\/j.celrep.2024.114750_bib62","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.143812","article-title":"microRNA-483 ameliorates hypercholesterolemia by inhibiting PCSK9 production","volume":"5","author":"Dong","year":"2020","journal-title":"JCI Insight"},{"key":"10.1016\/j.celrep.2024.114750_bib80","doi-asserted-by":"crossref","unstructured":"Hooper, M., Hardy, K., Handyside, A., Hunter, S., and Monk, M. (1987). HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells. Nature 326, 292-295. https:\/\/doi.org\/10.1038\/326292a0.","DOI":"10.1038\/326292a0"},{"key":"10.1016\/j.celrep.2024.114750_bib63","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/nbt.1929","article-title":"A resource of vectors and ES cells for targeted deletion of microRNAs in mice","volume":"29","author":"Prosser","year":"2011","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.celrep.2024.114750_bib81","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0012-1606(87)90132-1","article-title":"Buffalo rat liver cells produce a diffusible activity which inhibits the differentiation of murine embryonal carcinoma and embryonic stem cells","volume":"121","author":"Smith","year":"1987","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114750_bib69","doi-asserted-by":"crossref","first-page":"5080","DOI":"10.1093\/nar\/23.24.5080","article-title":"A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells","volume":"23","author":"Schwenk","year":"1995","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2024.114750_bib64","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1073\/pnas.0610155104","article-title":"Controlled expression of transgenes introduced by in\u00a0vivo electroporation","volume":"104","author":"Matsuda","year":"2007","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2024.114750_bib67","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0000162","article-title":"High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells","volume":"2","author":"Raymond","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.celrep.2024.114750_bib68","doi-asserted-by":"crossref","first-page":"e155","DOI":"10.1093\/nar\/gni146","article-title":"An ES cell system for rapid, spatial and temporal analysis of gene function in\u00a0vitro and in\u00a0vivo","volume":"33","author":"Mao","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2024.114750_bib65","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.cell.2013.01.031","article-title":"Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing","volume":"152","author":"Auyeung","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2024.114750_bib66","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.molcel.2017.03.013","article-title":"Genome-wide Mapping of DROSHA Cleavage Sites on Primary MicroRNAs and Noncanonical Substrates","volume":"66","author":"Kim","year":"2017","journal-title":"Mol. Cell."},{"key":"10.1016\/j.celrep.2024.114750_bib70","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.celrep.2024.114750_bib71","doi-asserted-by":"crossref","first-page":"W216","DOI":"10.1093\/nar\/gkac194","article-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","volume":"50","author":"Sherman","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2024.114750_bib72","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0021800","article-title":"REVIGO summarizes and visualizes long lists of gene ontology terms","volume":"6","author":"Supek","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.celrep.2024.114750_bib73","doi-asserted-by":"crossref","DOI":"10.1126\/science.aav1741","article-title":"The biochemical basis of microRNA targeting efficacy","volume":"366","author":"McGeary","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.celrep.2024.114750_bib74","first-page":"147","article-title":"Reproducibility and accuracy of body composition assessments in mice by dual energy x-ray absorptiometry and time domain nuclear magnetic resonance","volume":"7","author":"Halldorsdottir","year":"2009","journal-title":"Int. J. Body Compos. Res."},{"key":"10.1016\/j.celrep.2024.114750_bib75","doi-asserted-by":"crossref","first-page":"7717","DOI":"10.1038\/s41598-021-87292-x","article-title":"Autocrine IGF2 programmes \u03b2-cell plasticity under conditions of increased metabolic demand","volume":"11","author":"Sandovici","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2024.114750_bib76","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.devcel.2021.12.005","article-title":"The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth","volume":"57","author":"Sandovici","year":"2022","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2024.114750_bib77","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1242\/dmm.016337","article-title":"Phenotyping structural abnormalities in mouse embryos using high-resolution episcopic microscopy","volume":"7","author":"Weninger","year":"2014","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.celrep.2024.114750_bib78","first-page":"681","article-title":"Generation of volume data by episcopic three-dimensional imaging of embryos","volume":"2012","author":"Mohun","year":"2012","journal-title":"Cold Spring Harb. Protoc."},{"key":"10.1016\/j.celrep.2024.114750_bib79","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/s42003-021-02214-x","article-title":"Placental secretome characterization identifies candidates for pregnancy complications","volume":"4","author":"Napso","year":"2021","journal-title":"Commun. Biol."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221112472401101X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S221112472401101X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T17:59:15Z","timestamp":1733853555000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S221112472401101X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":81,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S221112472401101X"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2024.114750","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Overexpression of Igf2-derived Mir483 inhibits Igf1 expression and leads to developmental growth restriction and metabolic dysfunction in mice","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2024.114750","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"114750"}}