{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T22:40:38Z","timestamp":1774305638819,"version":"3.50.1"},"reference-count":65,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,5]],"date-time":"2024-11-05T00:00:00Z","timestamp":1730764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["UIDP\/04046\/2020"],"award-info":[{"award-number":["UIDP\/04046\/2020"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["810207-ARPCOMPLEXITY\/H2020"],"award-info":[{"award-number":["810207-ARPCOMPLEXITY\/H2020"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Foundation for Science and Technology","doi-asserted-by":"publisher","award":["PTDC\/SAU-BID\/115264\/2009"],"award-info":[{"award-number":["PTDC\/SAU-BID\/115264\/2009"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Foundation for Science and Technology","doi-asserted-by":"publisher","award":["UIDP\/04046\/2020"],"award-info":[{"award-number":["UIDP\/04046\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001871","name":"Foundation for Science and Technology","doi-asserted-by":"publisher","award":["UIDB\/04046\/2020"],"award-info":[{"award-number":["UIDB\/04046\/2020"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005765","name":"Universidade de Lisboa","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005765","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.celrep.2024.114998","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T08:35:17Z","timestamp":1732869317000},"page":"114998","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Thymus-forming potential of the second pharyngeal pouch and its regulation by local mesenchyme in avian embryos"],"prefix":"10.1016","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1861-4049","authenticated-orcid":false,"given":"Isabel","family":"Alcobia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0365-6916","authenticated-orcid":false,"given":"Margarida","family":"Gama-Carvalho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonor","family":"Magalh\u00e3es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vitor","family":"Proa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8869-1894","authenticated-orcid":false,"given":"Domingos","family":"Henrique","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6700-4976","authenticated-orcid":false,"given":"H\u00e9lia","family":"Neves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2024.114998_bib1","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1002\/eji.201545844","article-title":"Adult thymic epithelial cell (TEC) progenitors and TEC stem cells: Models and mechanisms for TEC development and maintenance","volume":"45","author":"Hamazaki","year":"2015","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.celrep.2024.114998_bib2","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.706244","article-title":"Thymus Degeneration and Regeneration","volume":"12","author":"Duah","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.celrep.2024.114998_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1084\/jem.142.1.17","article-title":"Tracing of cells of the avian thymus through embryonic life in interspecific chimeras","volume":"142","author":"Le Douarin","year":"1975","journal-title":"J.\u00a0Exp. Med."},{"key":"10.1016\/j.celrep.2024.114998_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1146\/annurev.immunol.26.021607.090408","article-title":"Thymus Organogenesis","volume":"26","author":"Rodewald","year":"2008","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.celrep.2024.114998_bib5","doi-asserted-by":"crossref","first-page":"6484","DOI":"10.4049\/jimmunol.176.11.6484","article-title":"Cervical thymus in the mouse","volume":"176","author":"Dooley","year":"2006","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2024.114998_bib6","first-page":"193","article-title":"The morphogenesis and histogenesis of the thymus gland in man: in which the origin of the Hassall\u2019s corpuscle of the human thymus is discovered","volume":"27","author":"Norris","year":"1938","journal-title":"Contrib. Embryol."},{"key":"10.1016\/j.celrep.2024.114998_bib7","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1126\/science.1123497","article-title":"Evidence for a functional second thymus in mice","volume":"312","author":"Terszowski","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.celrep.2024.114998_bib8","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/ar.1090790204","article-title":"On the origin of accessory thymus tissue, thymus IV: The occurrence in man","volume":"79","author":"Van Dyke","year":"1941","journal-title":"Anat. Rec."},{"key":"10.1016\/j.celrep.2024.114998_bib9","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/372103a0","article-title":"New member of the winged-helix protein family disrupted in mouse and rat nude mutations","volume":"372","author":"Nehls","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2024.114998_bib10","doi-asserted-by":"crossref","first-page":"5742","DOI":"10.1073\/pnas.93.12.5742","article-title":"The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors","volume":"93","author":"Blackburn","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2024.114998_bib11","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1126\/science.272.5263.886","article-title":"Two genetically separable steps in the differentiation of thymic epithelium","volume":"272","author":"Nehls","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.celrep.2024.114998_bib12","doi-asserted-by":"crossref","first-page":"5765","DOI":"10.3390\/ijms21165765","article-title":"Thymus Inception: Molecular Network in the Early Stages of Thymus Organogenesis","volume":"21","author":"Figueiredo","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.celrep.2024.114998_bib13","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/s41467-022-28067-4","article-title":"Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development","volume":"13","author":"Magaletta","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2024.114998_bib14","first-page":"367","article-title":"A cell atlas of human thymic development defines T\u00a0cell repertoire formation","volume":"1979","author":"Park","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.celrep.2024.114998_bib15","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.ydbio.2016.08.012","article-title":"Notch and Hedgehog in the thymus\/parathyroid common primordium: Crosstalk in organ formation","volume":"418","author":"Figueiredo","year":"2016","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib16","article-title":"Two-step Approach to Explore Early-and Late-stages of Organ Formation in the Avian Model: The Thymus and Parathyroid Glands Organogenesis Paradigm Video Link","volume":"136","author":"Figueiredo","year":"2018","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.celrep.2024.114998_bib17","article-title":"Isolation of Embryonic Tissues and Formation of Quail-Chicken Chimeric Organs Using The Thymus Example","volume":"144","author":"Figueiredo","year":"2019","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.celrep.2024.114998_bib18","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.ydbio.2011.10.022","article-title":"Modulation of Bmp4 signalling in the epithelial-mesenchymal interactions that take place in early thymus and parathyroid development in avian embryos","volume":"361","author":"Neves","year":"2012","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib19","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.ydbio.2011.02.012","article-title":"Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids","volume":"353","author":"Grevellec","year":"2011","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib20","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1006\/dbio.1995.1047","article-title":"undulated Phenotypes Suggest a Role of Pax-1 for the Development of Vertebral and Extravertebral Structures","volume":"167","author":"Dietrich","year":"1995","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib21","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1172\/JCI44630","article-title":"A Tbx1-Six1\/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis","volume":"121","author":"Guo","year":"2011","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.celrep.2024.114998_bib22","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1006\/dbio.2001.0342","article-title":"Hoxa3 and Pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis","volume":"236","author":"Su","year":"2001","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib23","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1242\/dev.122.1.23","article-title":"Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation","volume":"122","author":"Wallin","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.celrep.2024.114998_bib24","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nature02083","article-title":"Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis","volume":"426","author":"Li","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2024.114998_bib25","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/s41467-021-21346-6","article-title":"Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla","volume":"12","author":"Bautista","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2024.114998_bib26","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1038\/s41423-023-01102-0","article-title":"Insm1 regulates mTEC development and immune tolerance","volume":"20","author":"Tao","year":"2023","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.celrep.2024.114998_bib27","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.physbeh.2015.03.027","article-title":"The obesity-associated transcription factor ETV5 modulates circulating glucocorticoids","volume":"150","author":"Gutierrez-Aguilar","year":"2015","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.celrep.2024.114998_bib28","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1002\/jbmr.458","article-title":"MafB interacts with Gcm2 and regulates parathyroid hormone expression and parathyroid development","volume":"26","author":"Kamitani-Kawamoto","year":"2011","journal-title":"J.\u00a0Bone Miner. Res."},{"key":"10.1016\/j.celrep.2024.114998_bib29","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.gep.2012.10.001","article-title":"Expression of the Foxi2 and Foxi3 transcription factors during development of chicken sensory placodes and pharyngeal arches","volume":"13","author":"Khatri","year":"2013","journal-title":"Gene Expr. Patterns"},{"key":"10.1016\/j.celrep.2024.114998_bib30","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1597\/13-151","article-title":"Genome-wide Chromatin Mapping Defines AP2\u03b1 in the Etiology of Craniofacial Disorders","volume":"52","author":"Enkhmandakh","year":"2015","journal-title":"Cleft Palate. Craniofac. J."},{"key":"10.1016\/j.celrep.2024.114998_bib31","doi-asserted-by":"crossref","first-page":"3437","DOI":"10.1242\/dev.007906","article-title":"SOX3 activity during pharyngeal segmentation is required for craniofacial morphogenesis","volume":"134","author":"Rizzoti","year":"2007","journal-title":"Development"},{"key":"10.1016\/j.celrep.2024.114998_bib32","doi-asserted-by":"crossref","first-page":"2822","DOI":"10.1172\/JCI24156","article-title":"An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism","volume":"115","author":"Bowl","year":"2005","journal-title":"J.\u00a0Clin. Invest."},{"key":"10.1016\/j.celrep.2024.114998_bib33","doi-asserted-by":"crossref","DOI":"10.1242\/dmm.037051","article-title":"Wnt signaling in orofacial clefts: crosstalk, pathogenesis and models","volume":"12","author":"Reynolds","year":"2019","journal-title":"Dis. Model. Mech."},{"key":"10.1016\/j.celrep.2024.114998_bib34","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1002\/bdr2.1754","article-title":"Genetics and signaling mechanisms of orofacial clefts","volume":"112","author":"Reynolds","year":"2020","journal-title":"Birth Defects Res."},{"key":"10.1016\/j.celrep.2024.114998_bib35","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0070-2153(09)88008-3","article-title":"Chapter 8 Hox, Cdx, and Anteroposterior Patterning in the Mouse Embryo","volume":"88","author":"Young","year":"2009","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib36","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/dgd.12671","article-title":"The regulatory landscape of the Dlx gene system in branchial arches: Shared characteristics among Dlx bigene clusters and evolution","volume":"62","author":"Sumiyama","year":"2020","journal-title":"Dev. Growth Differ."},{"key":"10.1016\/j.celrep.2024.114998_bib37","doi-asserted-by":"crossref","first-page":"5213","DOI":"10.4049\/jimmunol.175.8.5213","article-title":"BMP signaling is required for normal thymus development","volume":"175","author":"Bleul","year":"2005","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.celrep.2024.114998_bib38","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ydbio.2009.12.026","article-title":"Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis","volume":"339","author":"Gordon","year":"2010","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib39","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0925-4773(02)00345-3","article-title":"Aortic arch and pharyngeal phenotype in the absence of BMP-dependent neural crest in the mouse","volume":"119","author":"Ohnemus","year":"2002","journal-title":"Mech. Dev."},{"key":"10.1016\/j.celrep.2024.114998_bib40","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1016\/j.modgep.2006.01.011","article-title":"Bmp4 and Noggin expression during early thymus and parathyroid organogenesis","volume":"6","author":"Patel","year":"2006","journal-title":"Gene Expr. Patterns"},{"key":"10.1016\/j.celrep.2024.114998_bib41","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/978-0-387-46954-6_6","article-title":"The contribution of the neural crest to the vertebrate body","volume":"589","author":"Dupin","year":"2006","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib42","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.mod.2018.07.010","article-title":"Gli2 is required for the induction and migration of Xenopus laevis neural crest","volume":"154","author":"Cerrizuela","year":"2018","journal-title":"Mech. Dev."},{"key":"10.1016\/j.celrep.2024.114998_bib43","doi-asserted-by":"crossref","first-page":"5761","DOI":"10.3390\/ijms22115761","article-title":"How Neural Crest Transcription Factors Contribute to Melanoma Heterogeneity, Cellular Plasticity, and Treatment Resistance","volume":"22","author":"Wessely","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.celrep.2024.114998_bib44","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.pneurobio.2015.07.001","article-title":"Zeb2: A multifunctional regulator of nervous system development","volume":"132","author":"Hegarty","year":"2015","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.celrep.2024.114998_bib45","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-00842-0","article-title":"Elevated levels of Wnt signaling disrupt thymus morphogenesis and function","volume":"7","author":"Swann","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2024.114998_bib46","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/s41592-019-0667-5","article-title":"NicheNet: modeling intercellular communication by linking ligands to target genes","volume":"17","author":"Browaeys","year":"2020","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2024.114998_bib47","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s12079-022-00669-z","article-title":"A review on Tsukushi: mammalian development, disorders, and therapy","volume":"16","author":"Istiaq","year":"2022","journal-title":"J.\u00a0Cell Commun. Signal."},{"key":"10.1016\/j.celrep.2024.114998_bib48","first-page":"582","article-title":"Disruption of CXCR4 signaling in pharyngeal neural crest cells causes DiGeorge syndrome-like malformations","volume":"143","author":"Escot","year":"2016","journal-title":"Development"},{"key":"10.1016\/j.celrep.2024.114998_bib49","doi-asserted-by":"crossref","first-page":"2959","DOI":"10.1038\/ncomms3959","article-title":"Transdifferentiation of parathyroid cells into cervical thymi promotes atypical T-cell development","volume":"4","author":"Li","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2024.114998_bib50","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1086\/399765","article-title":"Lillie\u2019s Development of the Chick. An Introduction to Embryology. Howard L. Hamilton","volume":"28","author":"Rudnick","year":"1953","journal-title":"Q.\u00a0Rev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib51","first-page":"8","article-title":"The palatine tonsil as an evolutionary novelty","volume":"523","author":"Slipka","year":"1996","journal-title":"Acta Otolaryngol. Suppl."},{"key":"10.1016\/j.celrep.2024.114998_bib52","doi-asserted-by":"crossref","first-page":"3229","DOI":"10.1242\/dev.122.10.3229","article-title":"Rhombencephalic neural crest segmentation is preserved throughout craniofacial ontogeny","volume":"122","author":"K\u00f6ntges","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.celrep.2024.114998_bib53","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/bs.ctdb.2020.03.001","article-title":"A Hox gene regulatory network for hindbrain segmentation","volume":"139","author":"Parker","year":"2020","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib54","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/aja.1001950404","article-title":"A series of normal stages in the development of the chick embryo. 1951","volume":"195","author":"Hamburger","year":"1992","journal-title":"Dev. Dyn."},{"key":"10.1016\/j.celrep.2024.114998_bib55","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2\u2212\u0394\u0394CT Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.celrep.2024.114998_bib56","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1242\/dev.128.7.1059","article-title":"The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain","volume":"128","author":"Etchevers","year":"2001","journal-title":"Development"},{"key":"10.1016\/j.celrep.2024.114998_bib57","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/375787a0","article-title":"Expression of a Delta homologue in prospective neurons in the chick","volume":"375","author":"Henrique","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2024.114998_bib58","first-page":"3","article-title":"Developmental stages of the Japanese quail","volume":"216","author":"Ainsworth","year":"2010","journal-title":"J.\u00a0Anat."},{"key":"10.1016\/j.celrep.2024.114998_bib59","doi-asserted-by":"crossref","first-page":"10","DOI":"10.14806\/ej.17.1.200","article-title":"Cutadapt removes adapter sequences from high-throughput sequencing reads","volume":"17","author":"Martin","year":"2011","journal-title":"EMBnet. j."},{"key":"10.1016\/j.celrep.2024.114998_bib60","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2014.00043","article-title":"Quality assessment and control of tissue specific RNA-seq libraries of Drosophila transgenic RNAi models","volume":"5","author":"Amaral","year":"2014","journal-title":"Front. Genet."},{"key":"10.1016\/j.celrep.2024.114998_bib61","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2024.114998_bib62","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/bioinformatics\/btu638","article-title":"HTSeq--a Python framework to work with high-throughput sequencing data","volume":"31","author":"Anders","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2024.114998_bib63","doi-asserted-by":"crossref","first-page":"R29","DOI":"10.1186\/gb-2014-15-2-r29","article-title":"voom: precision weights unlock linear model analysis tools for RNA-seq read counts","volume":"15","author":"Law","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2024.114998_bib64","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2024.114998_bib65","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1089\/omi.2011.0118","article-title":"clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters","volume":"16","author":"Yu","year":"2012","journal-title":"OMICS"}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124724013494?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124724013494?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T21:44:51Z","timestamp":1774302291000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124724013494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":65,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S2211124724013494"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2024.114998","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Thymus-forming potential of the second pharyngeal pouch and its regulation by local mesenchyme in avian embryos","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2024.114998","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"114998"}}