{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T17:23:17Z","timestamp":1793380997644,"version":"4.5.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100008455","name":"Medical School, University of Michigan","doi-asserted-by":"publisher","award":["SCR_019168"],"award-info":[{"award-number":["SCR_019168"]}],"id":[{"id":"10.13039\/100008455","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007449","name":"Takeda Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007449","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011684","name":"Crohn's & Colitis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011684","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["CA288546"],"award-info":[{"award-number":["CA288546"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["DK108901"],"award-info":[{"award-number":["DK108901"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["DK119219"],"award-info":[{"award-number":["DK119219"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JPMJFR220O"],"award-info":[{"award-number":["JPMJFR220O"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K22122"],"award-info":[{"award-number":["24K22122"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP23H00404"],"award-info":[{"award-number":["JP23H00404"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K27586"],"award-info":[{"award-number":["23K27586"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["23K17428"],"award-info":[{"award-number":["23K17428"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP21gm6310023"],"award-info":[{"award-number":["JP21gm6310023"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["FORCE JP25gm4010030"],"award-info":[{"award-number":["FORCE JP25gm4010030"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.celrep.2025.115974","type":"journal-article","created":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T14:39:43Z","timestamp":1752676783000},"page":"115974","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Transmission of maternal oral pathobionts to the infant gut predisposes offspring to exacerbated enteritis"],"prefix":"10.1016","volume":"44","author":[{"given":"Masafumi","family":"Haraguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeji","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natsuru","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kira L.","family":"Newman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Merritt G.","family":"Gillilland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijie","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid L.","family":"Bergin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takehiro","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Motooka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Sugihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sho","family":"Kitamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroko","family":"Nagao-Kitamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1980-4178","authenticated-orcid":false,"given":"Nobuhiko","family":"Kamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2025.115974_bib1","doi-asserted-by":"crossref","DOI":"10.1128\/MMBR.00036-17","article-title":"The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota","volume":"81","author":"Milani","year":"2017","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.celrep.2025.115974_bib2","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.708472","article-title":"The Role of Microbiota in Infant Health: From Early Life to Adulthood","volume":"12","author":"Yao","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.celrep.2025.115974_bib3","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.tim.2018.09.008","article-title":"The Human Microbiome and Child Growth - First 1000 Days and Beyond","volume":"27","author":"Robertson","year":"2019","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.celrep.2025.115974_bib4","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1126\/science.1219328","article-title":"Microbial exposure during early life has persistent effects on natural killer T cell function","volume":"336","author":"Olszak","year":"2012","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.celrep.2025.115974_bib5","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1016\/j.immuni.2019.02.014","article-title":"A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult","volume":"50","author":"Al Nabhani","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.celrep.2025.115974_bib6","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aab2271","article-title":"Early infancy microbial and metabolic alterations affect risk of childhood asthma","volume":"7","author":"Arrieta","year":"2015","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.celrep.2025.115974_bib7","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/embor.2012.32","article-title":"Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma","volume":"13","author":"Russell","year":"2012","journal-title":"EMBO Rep."},{"key":"10.1016\/j.celrep.2025.115974_bib8","first-page":"489","article-title":"Antibiotics in early life: dysbiosis and the damage done","volume":"42","author":"Neuman","year":"2018","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.celrep.2025.115974_bib9","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1038\/s41598-020-80583-9","article-title":"Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States","volume":"11","author":"Casaburi","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2025.115974_bib10","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1002\/ncp.10490","article-title":"Early-Life Gut Microbiome-The Importance of Maternal and Infant Factors in Its Establishment","volume":"35","author":"Kapourchali","year":"2020","journal-title":"Nutr. Clin. Pract."},{"key":"10.1016\/j.celrep.2025.115974_bib11","doi-asserted-by":"crossref","first-page":"5139","DOI":"10.1038\/s41467-022-32805-z","article-title":"A compendium of 32,277 metagenome-assembled genomes and over 80 million genes from the early-life human gut microbiome","volume":"13","author":"Zeng","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2025.115974_bib12","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.tim.2012.12.001","article-title":"Development of intestinal microbiota in infants and its impact on health","volume":"21","author":"Matamoros","year":"2013","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.celrep.2025.115974_bib13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/MPG.0b013e3181d1b11e","article-title":"Intestinal microbiota of 6-week-old infants across Europe: geographic influence beyond delivery mode, breast-feeding, and antibiotics","volume":"51","author":"Fallani","year":"2010","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.1016\/j.celrep.2025.115974_bib14","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.cmet.2021.02.002","article-title":"High-fiber diet mitigates maternal obesity-induced cognitive and social dysfunction in the offspring via gut-brain axis","volume":"33","author":"Liu","year":"2021","journal-title":"Cell Metab."},{"key":"10.1016\/j.celrep.2025.115974_bib15","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1016\/j.cell.2016.06.001","article-title":"Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring","volume":"165","author":"Buffington","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2025.115974_bib16","doi-asserted-by":"crossref","first-page":"14691","DOI":"10.1073\/pnas.1005963107","article-title":"Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa","volume":"107","author":"De Filippo","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2025.115974_bib17","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1126\/science.abj2972","article-title":"Robust variation in infant gut microbiome assembly across a spectrum of lifestyles","volume":"376","author":"Olm","year":"2022","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.celrep.2025.115974_bib18","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.chom.2018.06.005","article-title":"Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome","volume":"24","author":"Ferretti","year":"2018","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2025.115974_bib19","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/7247238","article-title":"A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease","volume":"2019","author":"Guan","year":"2019","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.celrep.2025.115974_bib20","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1053\/j.gastro.2014.02.009","article-title":"The microbiome in inflammatory bowel disease: current status and the future ahead","volume":"146","author":"Kostic","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.celrep.2025.115974_bib21","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1136\/gut.2003.025403","article-title":"Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease","volume":"53","author":"Ott","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.celrep.2025.115974_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/gut.53.1.1","article-title":"Dysbiosis in inflammatory bowel disease","volume":"53","author":"Tamboli","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.celrep.2025.115974_bib23","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/j.chom.2014.02.005","article-title":"The treatment-naive microbiome in new-onset Crohn's disease","volume":"15","author":"Gevers","year":"2014","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2025.115974_bib24","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1126\/science.aan4526","article-title":"Ectopic colonization of oral bacteria in the intestine drives T(H)1 cell induction and inflammation","volume":"358","author":"Atarashi","year":"2017","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.celrep.2025.115974_bib25","doi-asserted-by":"crossref","first-page":"3617","DOI":"10.1172\/JCI75436","article-title":"Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature","volume":"124","author":"Haberman","year":"2014","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.celrep.2025.115974_bib26","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.chom.2018.09.009","article-title":"Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course","volume":"24","author":"Schirmer","year":"2018","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2025.115974_bib27","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.cell.2020.05.048","article-title":"The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis","volume":"182","author":"Kitamoto","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2025.115974_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2023.112120","article-title":"Periodontal disease is associated with increased gut colonization of pathogenic Haemophilus parainfluenzae in patients with Crohn's disease","volume":"42","author":"Sohn","year":"2023","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2025.115974_bib29","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2317932","article-title":"The intestinal microbiome of inflammatory bowel disease across the pediatric age range","volume":"16","author":"Conrad","year":"2024","journal-title":"Gut Microbes"},{"key":"10.1016\/j.celrep.2025.115974_bib30","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2333463","article-title":"Oral pathobiont Klebsiella chaperon usher pili provide site-specific adaptation for the inflamed gut mucosa","volume":"16","author":"Guo","year":"2024","journal-title":"Gut Microbes"},{"key":"10.1016\/j.celrep.2025.115974_bib31","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1126\/science.aag2029","article-title":"Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens","volume":"356","author":"Kim","year":"2017","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.celrep.2025.115974_bib32","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017776","article-title":"The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response","volume":"6","author":"Nanthakumar","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.celrep.2025.115974_bib33","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/nature10228","article-title":"Control of TH17 cells occurs in the small intestine","volume":"475","author":"Esplugues","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.115974_bib34","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/prd.12295","article-title":"Periodontal diseases and adverse pregnancy outcomes: Mechanisms","volume":"83","author":"Figuero","year":"2020","journal-title":"Periodontology"},{"key":"10.1016\/j.celrep.2025.115974_bib35","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.03452-21","article-title":"High-Level Acquisition of Maternal Oral Bacteria in Formula-Fed Infant Oral Microbiota","volume":"13","author":"Kageyama","year":"2022","journal-title":"mBio"},{"key":"10.1016\/j.celrep.2025.115974_bib36","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/s41368-020-0082-x","article-title":"Oral microbiome: possible harbinger for children's health","volume":"12","author":"Xiao","year":"2020","journal-title":"Int. J. Oral Sci."},{"key":"10.1016\/j.celrep.2025.115974_bib37","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1046\/j.0960-7439.2001.00311.x","article-title":"Prevalence of salivary Streptococcus mutans in mothers and in their preschool children","volume":"12","author":"Thorild","year":"2002","journal-title":"Int. J. Paediatr. Dent."},{"key":"10.1016\/j.celrep.2025.115974_bib38","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1002533","article-title":"Revised Estimates for the Number of Human and Bacteria Cells in the Body","volume":"14","author":"Sender","year":"2016","journal-title":"PLoS Biol."},{"key":"10.1016\/j.celrep.2025.115974_bib39","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/s41586-022-05546-8","article-title":"Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies","volume":"613","author":"Kennedy","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.115974_bib40","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1016\/j.chom.2024.05.004","article-title":"Paternal and induced gut microbiota seeding complement mother-to-infant transmission","volume":"32","author":"Dubois","year":"2024","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2025.115974_bib41","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1126\/science.1145697","article-title":"Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid","volume":"317","author":"Mucida","year":"2007","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.celrep.2025.115974_bib42","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1038\/s41590-019-0360-y","article-title":"Author Correction: Hobit- and Blimp-1-driven CD4(+) tissue-resident memory T cells control chronic intestinal inflammation","volume":"20","author":"Zundler","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.celrep.2025.115974_bib43","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1093\/ecco-jcc\/jjz010","article-title":"CD4+ Tissue-resident Memory T Cells Expand and Are a Major Source of Mucosal Tumour Necrosis Factor alpha in Active Crohn's Disease","volume":"13","author":"Bishu","year":"2019","journal-title":"J. Crohns Colitis"},{"key":"10.1016\/j.celrep.2025.115974_bib44","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/s41575-020-0331-7","article-title":"Intestinal epithelial glycosylation in homeostasis and gut microbiota interactions in IBD. Nature reviews","volume":"17","author":"Kudelka","year":"2020","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.celrep.2025.115974_bib45","doi-asserted-by":"crossref","DOI":"10.1172\/JCI141676","article-title":"DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk","volume":"131","author":"Grasberger","year":"2021","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.celrep.2025.115974_bib46","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2023.2265138","article-title":"Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes","volume":"15","author":"Bergsten","year":"2023","journal-title":"Gut Microbes"},{"key":"10.1016\/j.celrep.2025.115974_bib47","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2025.115974_bib48","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1177\/0023677214544728","article-title":"A simple cage-autonomous method for the maintenance of the barrier status of germ-free mice during experimentation","volume":"48","author":"Hecht","year":"2014","journal-title":"Lab. Anim."},{"key":"10.1016\/j.celrep.2025.115974_bib49","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.jcmgh.2016.02.003","article-title":"Functional Characterization of Inflammatory Bowel Disease-Associated Gut Dysbiosis in Gnotobiotic Mice","volume":"2","author":"Nagao-Kitamoto","year":"2016","journal-title":"Cell. Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.celrep.2025.115974_bib50","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1080\/19490976.2015.1064576","article-title":"Potential for using a hermetically-sealed, positive-pressured isocage system for studies involving germ-free mice outside a flexible-film isolator","volume":"6","author":"Paik","year":"2015","journal-title":"Gut Microbes"},{"key":"10.1016\/j.celrep.2025.115974_bib51","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1000412","article-title":"Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research","volume":"8","author":"Kilkenny","year":"2010","journal-title":"PLoS Biol."},{"key":"10.1016\/j.celrep.2025.115974_bib52","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/j.chom.2013.04.005","article-title":"Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavity","volume":"13","author":"Jiao","year":"2013","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.celrep.2025.115974_bib53","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1038\/s41596-018-0035-4","article-title":"An experimental murine model to study periodontitis","volume":"13","author":"Marchesan","year":"2018","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2025.115974_bib54","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1084\/jem.20181365","article-title":"CD4(+) resident memory T cells dominate immunosurveillance and orchestrate local recall responses","volume":"216","author":"Beura","year":"2019","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.celrep.2025.115974_bib55","doi-asserted-by":"crossref","first-page":"7537","DOI":"10.1128\/AEM.01541-09","article-title":"Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communities","volume":"75","author":"Schloss","year":"2009","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.celrep.2025.115974_bib56","doi-asserted-by":"crossref","first-page":"R60","DOI":"10.1186\/gb-2011-12-6-r60","article-title":"Metagenomic biomarker discovery and explanation","volume":"12","author":"Segata","year":"2011","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2025.115974_bib57","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1186\/s12864-021-07746-4","article-title":"Benchmark of 16S rRNA gene amplicon sequencing using Japanese gut microbiome data from the V1-V2 and V3-V4 primer sets","volume":"22","author":"Kameoka","year":"2021","journal-title":"BMC Genom."},{"key":"10.1016\/j.celrep.2025.115974_bib58","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abj1895","article-title":"Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in mice","volume":"14","author":"De Palma","year":"2022","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.celrep.2025.115974_bib59","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1038\/s41596-019-0128-8","article-title":"Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0)","volume":"14","author":"Mi","year":"2019","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2025.115974_bib60","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1101\/gr.6202607","article-title":"A systems biology approach for pathway level analysis","volume":"17","author":"Draghici","year":"2007","journal-title":"Genome Res."},{"key":"10.1016\/j.celrep.2025.115974_bib61","first-page":"238","article-title":"Clinicopathologic study of dextran sulfate sodium experimental murine colitis","volume":"69","author":"Cooper","year":"1993","journal-title":"Lab. Invest."},{"key":"10.1016\/j.celrep.2025.115974_bib62","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/1746-6148-9-123","article-title":"Multiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology--a systematic review","volume":"9","author":"Klopfleisch","year":"2013","journal-title":"BMC Vet. Res."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124725007454?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124725007454?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T11:10:45Z","timestamp":1778843445000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124725007454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":62,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S2211124725007454"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2025.115974","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transmission of maternal oral pathobionts to the infant gut predisposes offspring to exacerbated enteritis","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2025.115974","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"115974"}}