{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T23:46:02Z","timestamp":1792107962705,"version":"4.4.0"},"reference-count":74,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP23wm0625001"],"award-info":[{"award-number":["JP23wm0625001"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP19dm0207071"],"award-info":[{"award-number":["JP19dm0207071"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21H04785"],"award-info":[{"award-number":["21H04785"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20H05915"],"award-info":[{"award-number":["20H05915"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22K18644"],"award-info":[{"award-number":["22K18644"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24KJ0590"],"award-info":[{"award-number":["24KJ0590"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.celrep.2025.116208","type":"journal-article","created":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T14:36:23Z","timestamp":1756996583000},"page":"116208","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["FMR1 mutant marmosets show fragile X syndrome phenotypes"],"prefix":"10.1016","volume":"44","author":[{"given":"Maria","family":"Harbers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zefeng","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harumi","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiko","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoki","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moe","family":"Tamano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Sakai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimiko","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Sugaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosuke","family":"Itoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanobu","family":"Kano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8192-0778","authenticated-orcid":false,"given":"Atsu","family":"Aiba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2025.116208_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2017.65","article-title":"Fragile X syndrome","volume":"3","author":"Hagerman","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.celrep.2025.116208_bib2","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1399-0004.2009.01237.x","article-title":"Screening and instability of FMR1 alleles in a prospective sample of 24,449 mother-newborn pairs from the general population","volume":"76","author":"Levesque","year":"2009","journal-title":"Clin. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib3","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ajhg.2009.09.007","article-title":"Incidence of fragile X syndrome by newborn screening for methylated FMR1 DNA","volume":"85","author":"Coffee","year":"2009","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib4","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1002\/ajmg.a.31388","article-title":"ADHD symptoms in children with FXS","volume":"140","author":"Sullivan","year":"2006","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib5","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1111\/j.1469-8749.2002.tb00277.x","article-title":"Epilepsy in fragile X syndrome","volume":"44","author":"Berry-Kravis","year":"2002","journal-title":"Dev. Med. Child Neurol."},{"key":"10.1016\/j.celrep.2025.116208_bib6","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0387-7604(02)00102-X","article-title":"Epilepsy in fragile X syndrome","volume":"24","author":"Incorpora","year":"2002","journal-title":"Brain Dev."},{"key":"10.1016\/j.celrep.2025.116208_bib7","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1352\/0895-8017(2001)106<0216:RAECDO>2.0.CO;2","article-title":"Receptive and expressive communication development of young males with fragile X syndrome","volume":"106","author":"Roberts","year":"2001","journal-title":"Am. J. Ment. Retard."},{"key":"10.1016\/j.celrep.2025.116208_bib8","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s11689-010-9067-y","article-title":"Clinical assessment of DSM-IV anxiety disorders in fragile X syndrome: prevalence and characterization","volume":"3","author":"Cordeiro","year":"2011","journal-title":"J. Neurodev. Disord."},{"key":"10.1016\/j.celrep.2025.116208_bib9","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1007\/s10803-017-3081-9","article-title":"Autism Spectrum Disorder Symptoms in Infants with Fragile X Syndrome: A Prospective Case Series","volume":"47","author":"Hogan","year":"2017","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.celrep.2025.116208_bib10","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1002\/(SICI)1096-8628(19990402)83:4<268::AID-AJMG7>3.0.CO;2-K","article-title":"Electrodermal responses to sensory stimuli in individuals with fragile X syndrome: a preliminary report","volume":"83","author":"Miller","year":"1999","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib11","first-page":"1025","article-title":"Mental status of females with an FMR1 gene full mutation","volume":"58","author":"de Vries","year":"1996","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib12","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1136\/jmg.37.8.603","article-title":"Twin sisters, monozygotic with the fragile X mutation, but with a different phenotype","volume":"37","author":"Willemsen","year":"2000","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/jhg.2010.140","article-title":"Four sisters compound heterozygotes for the pre- and full mutation in fragile X syndrome and a complete inactivation of X-functional chromosome: implications for genetic counseling","volume":"56","author":"Martorell","year":"2011","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib14","first-page":"23","article-title":"Fmr1 Knockout Mice: A Model to Study Fragile X Mental Retardation","volume":"78","author":"Bakker","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2025.116208_bib15","doi-asserted-by":"crossref","first-page":"118","DOI":"10.5582\/irdr.2014.01024","article-title":"Modeling fragile X syndrome in the Fmr1 knockout mouse","volume":"3","author":"Kazdoba","year":"2014","journal-title":"Intractable Rare Dis. Res."},{"key":"10.1016\/j.celrep.2025.116208_bib16","doi-asserted-by":"crossref","first-page":"7746","DOI":"10.1073\/pnas.122205699","article-title":"Altered synaptic plasticity in a mouse model of fragile X mental retardation","volume":"99","author":"Huber","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2025.116208_bib17","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/(SICI)1096-8628(19990402)83:4<248::AID-AJMG3>3.0.CO;2-1","article-title":"Synaptic synthesis of the Fragile X protein: Possible involvement in synapse maturation and elimination","volume":"83","author":"Weiler","year":"1999","journal-title":"Am. J. Med. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib18","doi-asserted-by":"crossref","first-page":"5395","DOI":"10.1073\/pnas.94.10.5395","article-title":"Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation","volume":"94","author":"Weiler","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2025.116208_bib19","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.neuron.2007.12.001","article-title":"Correction of fragile X syndrome in mice","volume":"56","author":"Dolen","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116208_bib20","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1038\/nm0308-249","article-title":"Reducing glutamate signaling pays off in fragile X","volume":"14","author":"Bassell","year":"2008","journal-title":"Nat. Med."},{"key":"10.1016\/j.celrep.2025.116208_bib21","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.tins.2004.04.009","article-title":"The mGluR theory of fragile X mental retardation","volume":"27","author":"Bear","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib22","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aab4109","article-title":"Mavoglurant in fragile X syndrome: Results of two randomized, double-blind, placebo-controlled trials","volume":"8","author":"Berry-Kravis","year":"2016","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.celrep.2025.116208_bib23","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-99656-4","article-title":"Efficient marmoset genome engineering by autologous embryo transfer and CRISPR\/Cas9 technology","volume":"11","author":"Abe","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2025.116208_bib24","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.neuron.2016.03.018","article-title":"Marmosets: A Neuroscientific Model of Human Social Behavior","volume":"90","author":"Miller","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116208_bib25","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1038\/s41593-018-0209-y","article-title":"DeepLabCut: markerless pose estimation of user-defined body parts with deep learning","volume":"21","author":"Mathis","year":"2018","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib26","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1038\/s41596-019-0176-0","article-title":"Using DeepLabCut for 3D markerless pose estimation across species and behaviors","volume":"14","author":"Nath","year":"2019","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2025.116208_bib27","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2021.736255","article-title":"Seizures in Fragile X Syndrome: Associations and Longitudinal Analysis of a Large Clinic-Based Cohort","volume":"9","author":"Berry-Kravis","year":"2021","journal-title":"Front. Pediatr."},{"key":"10.1016\/j.celrep.2025.116208_bib28","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1016\/j.tig.2017.07.008","article-title":"Multifarious Functions of the Fragile X Mental Retardation Protein","volume":"33","author":"Davis","year":"2017","journal-title":"Trends Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib29","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1093\/hmg\/5.6.809","article-title":"FMRP is associated to the ribosomes via RNA","volume":"5","author":"Tamanini","year":"1996","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib30","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/ng0196-91","article-title":"The fragile X mental retardation protein is associated with ribosomes","volume":"12","author":"Khandjian","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2025.116208_bib31","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-022-30979-0","article-title":"Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome","volume":"13","author":"Seo","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2025.116208_bib32","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1038\/s41593-021-00913-6","article-title":"A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies","volume":"24","author":"Kang","year":"2021","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib33","doi-asserted-by":"crossref","first-page":"30400","DOI":"10.1073\/pnas.2009161117","article-title":"FMRP links optimal codons to mRNA stability in neurons","volume":"117","author":"Shu","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2025.116208_bib34","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1111\/epi.17547","article-title":"Genes4Epilepsy: An epilepsy gene resource","volume":"64","author":"Oliver","year":"2023","journal-title":"Epilepsia"},{"key":"10.1016\/j.celrep.2025.116208_bib35","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neuropharm.2012.11.028","article-title":"Fragile X syndrome: from targets to treatments","volume":"68","author":"Wijetunge","year":"2013","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.celrep.2025.116208_bib36","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1007\/s10803-005-0008-7","article-title":"Video analysis of sensory-motor features in infants with fragile X syndrome at 9-12 months of age","volume":"35","author":"Baranek","year":"2005","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.celrep.2025.116208_bib37","article-title":"Early communication development in infants and toddlers with Fragile X syndrome","volume":"7","author":"Mattie","year":"2022","journal-title":"Autism Dev. Lang Imp"},{"key":"10.1016\/j.celrep.2025.116208_bib38","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1044\/2020_JSLHR-20-00198","article-title":"Language Development From Early Childhood to Adolescence in Youths With Fragile X Syndrome","volume":"63","author":"Brady","year":"2020","journal-title":"J. Speech Lang. Hear. R"},{"key":"10.1016\/j.celrep.2025.116208_bib39","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1007\/s10764-008-9250-0","article-title":"Structure and usage of the vocal repertoire of Callithrix jacchus","volume":"29","author":"Bezerra","year":"2008","journal-title":"Int. J. Primatol."},{"key":"10.1016\/j.celrep.2025.116208_bib40","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1016\/j.cub.2013.09.005","article-title":"Coupled Oscillator Dynamics of Vocal Turn-Taking in Monkeys","volume":"23","author":"Takahashi","year":"2013","journal-title":"Curr. Biol."},{"key":"10.1016\/j.celrep.2025.116208_bib41","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1126\/science.aab1058","article-title":"LANGUAGE DEVELOPMENT. The developmental dynamics of marmoset monkey vocal production","volume":"349","author":"Takahashi","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.celrep.2025.116208_bib42","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1121\/1.2225899","article-title":"Acoustic analysis of vocal development in a New World primate, the common marmoset (Callithrix jacchus)","volume":"120","author":"Pistorio","year":"2006","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.celrep.2025.116208_bib43","doi-asserted-by":"crossref","DOI":"10.1186\/s11689-017-9191-z","article-title":"A resting EEG study of neocortical hyperexcitability and altered functional connectivity in fragile X syndrome","volume":"9","author":"Wang","year":"2017","journal-title":"J. Neurodev. Disord."},{"key":"10.1016\/j.celrep.2025.116208_bib44","doi-asserted-by":"crossref","DOI":"10.1038\/s42003-022-03395-9","article-title":"Neocortical localization and thalamocortical modulation of neuronal hyperexcitability contribute to Fragile X Syndrome","volume":"5","author":"Pedapati","year":"2022","journal-title":"Commun. Biol."},{"key":"10.1016\/j.celrep.2025.116208_bib45","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-72935-6","article-title":"Validating brain activity measures as reliable indicators of individual diagnostic group and genetically mediated sub-group membership Fragile X Syndrome","volume":"14","author":"Ethridge","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2025.116208_bib46","doi-asserted-by":"crossref","DOI":"10.3389\/fnint.2019.00060","article-title":"Auditory EEG Biomarkers in Fragile X Syndrome: Clinical Relevance","volume":"13","author":"Ethridge","year":"2019","journal-title":"Front. Integr. Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib47","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1007\/s10803-011-1176-2","article-title":"Reliability of eye tracking and pupillometry measures in individuals with fragile X syndrome","volume":"41","author":"Farzin","year":"2011","journal-title":"J. Autism Dev. Disord."},{"key":"10.1016\/j.celrep.2025.116208_bib48","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1523\/JNEUROSCI.3899-13.2014","article-title":"Active vision in marmosets: a model system for visual neuroscience","volume":"34","author":"Mitchell","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib49","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1002\/jdn.10217","article-title":"Cerebellum neuropathology and motor skill deficits in fragile X syndrome","volume":"82","author":"Chen","year":"2022","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib50","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2020-011528","article-title":"Emergence of Developmental Delay in Infants and Toddlers With an FMR1 Mutation","volume":"147","author":"Wheeler","year":"2021","journal-title":"Pediatrics"},{"key":"10.1016\/j.celrep.2025.116208_bib51","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1093\/sleep\/33.5.679","article-title":"Prevalence, Nature, and Correlates of Sleep Problems Among Children with Fragile X Syndrome Based on a Large Scale Parent Survey","volume":"33","author":"Kronk","year":"2010","journal-title":"Sleep"},{"key":"10.1016\/j.celrep.2025.116208_bib52","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.gde.2020.05.040","article-title":"The dawn of non-human primate models for neurodevelopmental disorders","volume":"65","author":"Aida","year":"2020","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.celrep.2025.116208_bib53","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/s41586-019-1278-0","article-title":"Atypical behaviour and connectivity in SHANK3-mutant macaques","volume":"570","author":"Zhou","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.116208_bib54","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.cell.2017.04.035","article-title":"Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys","volume":"169","author":"Chen","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2025.116208_bib55","doi-asserted-by":"crossref","DOI":"10.1016\/j.eplepsyres.2022.106891","article-title":"Spontaneous seizures in adult Fmr1 knockout mice: FVB.129P2-Pde6b+ Tyrc-ch Fmr1tm1Cgr\/J","volume":"182","author":"Armstrong","year":"2022","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.celrep.2025.116208_bib56","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ijdevneu.2014.07.002","article-title":"EEG abnormalities and seizures in genetically diagnosed Fragile X syndrome","volume":"38","author":"Heard","year":"2014","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib57","doi-asserted-by":"crossref","DOI":"10.1186\/s12888-016-1020-5","article-title":"Characterization, treatment patterns, and patient-related outcomes of patients with Fragile X syndrome in Germany: final results of the observational EXPLAIN-FXS study","volume":"16","author":"Haessler","year":"2016","journal-title":"BMC Psychiatry"},{"key":"10.1016\/j.celrep.2025.116208_bib58","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.718953","article-title":"mGluR5 Negative Modulators for Fragile X: Treatment Resistance and Persistence","volume":"12","author":"Stoppel","year":"2021","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.celrep.2025.116208_bib59","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ijdevneu.2014.05.003","article-title":"Alterations of visual and auditory evoked potentials in fragile X syndrome","volume":"36","author":"Knoth","year":"2014","journal-title":"Int. J. Dev. Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib60","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1352\/1944-7558-125.6.449","article-title":"Development of Neural Response to Novel Sounds in Fragile X Syndrome: Potential Biomarkers","volume":"125","author":"Ethridge","year":"2020","journal-title":"Am. J. Intellect. Dev. Disabil."},{"key":"10.1016\/j.celrep.2025.116208_bib61","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci9010011","article-title":"Closing the Gender Gap in Fragile X Syndrome: Review of Females with Fragile X Syndrome and Preliminary Research Findings","volume":"9","author":"Bartholomay","year":"2019","journal-title":"Brain Sci."},{"key":"10.1016\/j.celrep.2025.116208_bib62","doi-asserted-by":"crossref","first-page":"D462","DOI":"10.1093\/nar\/gkae1032","article-title":"jPOST environment accelerates the reuse and reanalysis of public proteome mass spectrometry data","volume":"53","author":"Okuda","year":"2025","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2025.116208_bib63","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/s41587-019-0032-3","article-title":"CRISPResso2 provides accurate and rapid genome editing sequence analysis","volume":"37","author":"Clement","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.celrep.2025.116208_bib64","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2025.116208_bib65","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2013","journal-title":"Bioinformatics"},{"key":"10.1016\/j.celrep.2025.116208_bib66","doi-asserted-by":"crossref","DOI":"10.1186\/s13059-014-0550-8","article-title":"Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2","volume":"15","author":"Love","year":"2014","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2025.116208_bib67","series-title":"R: A Language and Environment for Statistical Computing","year":"2006"},{"key":"10.1016\/j.celrep.2025.116208_bib68","doi-asserted-by":"crossref","first-page":"W216","DOI":"10.1093\/nar\/gkac194","article-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","volume":"50","author":"Sherman","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2025.116208_bib69","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/s41592-019-0638-x","article-title":"DIA-NN: neural networks and interference correction enable deep proteome coverage in high throughput","volume":"17","author":"Demichev","year":"2020","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2025.116208_bib70","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jneumeth.2003.10.009","article-title":"EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis","volume":"134","author":"Delorme","year":"2004","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.celrep.2025.116208_bib71","doi-asserted-by":"crossref","DOI":"10.3389\/fnhum.2014.00213","article-title":"ERPLAB: an open-source toolbox for the analysis of event-related potentials","volume":"8","author":"Lopez-Calderon","year":"2014","journal-title":"Front. Hum. Neurosci."},{"key":"10.1016\/j.celrep.2025.116208_bib72","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis","volume":"9","author":"Schneider","year":"2012","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2025.116208_bib73","article-title":"A novel \u201cdip-in electrode\u201d method for electrode application to record noninvasive scalp electroencephalograms and evoked potentials in an awake common marmoset","volume":"2","author":"Itoh","year":"2022","journal-title":"Neuroimage. Rep."},{"key":"10.1016\/j.celrep.2025.116208_bib74","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.bbr.2014.09.020","article-title":"Three-dimensional motion analysis of arm-reaching movements in healthy and hemispinalized common marmosets","volume":"275","author":"Takemi","year":"2014","journal-title":"Behav. Brain Res."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124725009799?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124725009799?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:32:01Z","timestamp":1790137921000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124725009799"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":74,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S2211124725009799"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2025.116208","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"FMR1 mutant marmosets show fragile X syndrome phenotypes","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2025.116208","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116208"}}