{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T13:01:58Z","timestamp":1790600518015,"version":"4.1.0"},"reference-count":88,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018231","name":"Aligning Science Across Parkinson's","doi-asserted-by":"publisher","award":["ASAP-020529"],"award-info":[{"award-number":["ASAP-020529"]}],"id":[{"id":"10.13039\/100018231","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000016","name":"U.S. Department of Health and Human Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000016","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["NS003135"],"award-info":[{"award-number":["NS003135"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.celrep.2025.116555","type":"journal-article","created":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T01:13:00Z","timestamp":1764205980000},"page":"116555","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum"],"prefix":"10.1016","volume":"44","author":[{"given":"Samuel G.","family":"Brill-Weil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul F.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Yanez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna M.","family":"Lipkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faye H.","family":"Clever","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renshu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1445-1457","authenticated-orcid":false,"given":"Zayd M.","family":"Khaliq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2025.116555_bib1","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1523\/JNEUROSCI.4029-08.2009","article-title":"Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum","volume":"29","author":"Matsuda","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib2","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3389\/fnana.2015.00059","article-title":"Long-range projection neurons of the mouse ventral tegmental area: a single-cell axon tracing analysis","volume":"9","author":"Aransay","year":"2015","journal-title":"Front. Neuroanat."},{"key":"10.1016\/j.celrep.2025.116555_bib3","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1471-4159.1992.tb09391.x","article-title":"Dynamic observation of dopamine autoreceptor effects in rat striatal slices","volume":"59","author":"Kennedy","year":"1992","journal-title":"J. Neurochem."},{"key":"10.1016\/j.celrep.2025.116555_bib4","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1152\/jn.2001.85.6.2468","article-title":"H2O2 is a novel, endogenous modulator of synaptic dopamine release","volume":"85","author":"Chen","year":"2001","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.celrep.2025.116555_bib5","doi-asserted-by":"crossref","first-page":"10585","DOI":"10.1523\/JNEUROSCI.23-33-10585.2003","article-title":"Glutamate spillover in the striatum depresses dopaminergic transmission by activating group I metabotropic glutamate receptors","volume":"23","author":"Zhang","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib6","doi-asserted-by":"crossref","first-page":"8124","DOI":"10.1073\/pnas.1508846112","article-title":"Muscarinic regulation of dopamine and glutamate transmission in the nucleus accumbens","volume":"112","author":"Shin","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2025.116555_bib7","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.baga.2016.02.001","article-title":"Striatal dopamine neurotransmission: Regulation of release and uptake","volume":"6","author":"Sulzer","year":"2016","journal-title":"Basal Ganglia"},{"key":"10.1016\/j.celrep.2025.116555_bib8","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1523\/JNEUROSCI.1548-21.2021","article-title":"Dopamine release in nucleus accumbens is under tonic inhibition by adenosine A1 receptors regulated by astrocytic ENT1 and dysregulated by ethanol","volume":"42","author":"Roberts","year":"2022","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib9","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.1692-24.2025","article-title":"Local regulation of striatal dopamine release shifts from predominantly cholinergic in mice to GABAergic in macaques","volume":"45","author":"Shin","year":"2025","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib10","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0006-8993(92)90851-Y","article-title":"Tonic inhibition of striatal dopamine transmission: effects of benzodiazepine and GABAA receptor antagonists on extracellular dopamine levels","volume":"599","author":"Gruen","year":"1992","journal-title":"Brain Res."},{"key":"10.1016\/j.celrep.2025.116555_bib11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0014-2999(95)00369-V","article-title":"Tonic GABA-ergic modulation of striatal dopamine release studied by in vivo microdialysis in the freely moving rat","volume":"284","author":"Smolders","year":"1995","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.celrep.2025.116555_bib12","doi-asserted-by":"crossref","first-page":"3472","DOI":"10.1111\/ejn.12733","article-title":"GABAB modulation of dopamine release in the nucleus accumbens core","volume":"40","author":"Pitman","year":"2014","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib13","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1523\/JNEUROSCI.2028-18.2018","article-title":"Inhibition of nigrostriatal dopamine release by striatal GABAA and GABAB receptors","volume":"39","author":"Lopes","year":"2019","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib14","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.55729","article-title":"Axonal mechanisms mediating \u03b3-aminobutyric acid receptor type A (GABA-A) inhibition of striatal dopamine release","volume":"9","author":"Kramer","year":"2020","journal-title":"eLife"},{"key":"10.1016\/j.celrep.2025.116555_bib15","doi-asserted-by":"crossref","first-page":"4139","DOI":"10.1016\/j.cub.2021.06.081","article-title":"Striatal low-threshold spiking interneurons locally gate dopamine","volume":"31","author":"Holly","year":"2021","journal-title":"Curr. Biol."},{"key":"10.1016\/j.celrep.2025.116555_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2024.113834","article-title":"GABA co-released from striatal dopamine axons dampens phasic dopamine release through autoregulatory GABAA receptors","volume":"43","author":"Patel","year":"2024","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2025.116555_bib17","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nn1243","article-title":"Frequency-dependent modulation of dopamine release by nicotine","volume":"7","author":"Zhang","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib18","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/nn1244","article-title":"Nicotine amplifies reward-related dopamine signals in striatum","volume":"7","author":"Rice","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib19","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.neuron.2012.04.038","article-title":"Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons","volume":"75","author":"Threlfell","year":"2012","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116555_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2014.00188","article-title":"Local control of striatal dopamine release","volume":"8","author":"Cachope","year":"2014","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib21","doi-asserted-by":"crossref","DOI":"10.1038\/srep37834","article-title":"Nicotinic and opioid receptor regulation of striatal dopamine D2-receptor mediated transmission","volume":"6","author":"Mamaligas","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2025.116555_bib22","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1016\/j.neuron.2022.07.011","article-title":"Synaptic-like axo-axonal transmission from striatal cholinergic interneurons onto dopaminergic fibers","volume":"110","author":"Kramer","year":"2022","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116555_bib23","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1126\/science.abn0532","article-title":"An action potential initiation mechanism in distal axons for the control of dopamine release","volume":"375","author":"Liu","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.celrep.2025.116555_bib24","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1038\/nn769","article-title":"Endogenous nicotinic cholinergic activity regulates dopamine release in the striatum","volume":"4","author":"Zhou","year":"2001","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib25","doi-asserted-by":"crossref","first-page":"2086","DOI":"10.1523\/JNEUROSCI.3064-16.2017","article-title":"Cholinergic interneurons underlie spontaneous dopamine release in nucleus accumbens","volume":"37","author":"Yorgason","year":"2017","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib26","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1152\/jn.1992.68.1.197","article-title":"Shunting of excitatory input to dentate gyrus granule cells by a depolarizing GABAA receptor-mediated postsynaptic conductance","volume":"68","author":"Staley","year":"1992","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.celrep.2025.116555_bib27","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/S0896-6273(02)00820-6","article-title":"Gain modulation from background synaptic input","volume":"35","author":"Chance","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116555_bib28","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/S0896-6273(03)00200-9","article-title":"Shunting inhibition modulates neuronal gain during synaptic excitation","volume":"38","author":"Mitchell","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116555_bib29","series-title":"Progress in Brain Research","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0079-6123(06)60005-8","article-title":"The cellular, molecular and ionic basis of GABAA receptor signalling","author":"Farrant","year":"2007"},{"key":"10.1016\/j.celrep.2025.116555_bib30","doi-asserted-by":"crossref","first-page":"6357","DOI":"10.1523\/JNEUROSCI.0605-23.2023","article-title":"Axon initial segment GABA inhibits action potential generation throughout periadolescent development","volume":"43","author":"Lipkin","year":"2023","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib31","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1124\/jpet.104.070417","article-title":"Electrophysiological, pharmacological, and molecular evidence for \u03b17-nicotinic acetylcholine receptors in rat midbrain dopamine neurons","volume":"311","author":"Wu","year":"2004","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.celrep.2025.116555_bib32","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/s41586-023-05828-9","article-title":"Fast and sensitive GCaMP calcium indicators for imaging neural populations","volume":"615","author":"Zhang","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.116555_bib33","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/384170a0","article-title":"Timing of neurotransmission at fast synapses in the mammalian brain","volume":"384","author":"Sabatini","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.116555_bib34","doi-asserted-by":"crossref","first-page":"3425","DOI":"10.1523\/JNEUROSCI.17-10-03425.1997","article-title":"Control of neurotransmitter release by presynaptic waveform at the granule cell to purkinje cell synapse","volume":"17","author":"Sabatini","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib35","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1016\/S0006-3495(98)77867-1","article-title":"Optical measurement of presynaptic calcium currents","volume":"74","author":"Sabatini","year":"1998","journal-title":"Biophys. J."},{"key":"10.1016\/j.celrep.2025.116555_bib36","doi-asserted-by":"crossref","first-page":"3559","DOI":"10.1113\/jphysiol.2014.271825","article-title":"Temporal components of cholinergic terminal to dopaminergic terminal transmission in dorsal striatum slices of mice","volume":"592","author":"Wang","year":"2014","journal-title":"J. Physiol."},{"key":"10.1016\/j.celrep.2025.116555_bib37","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1038\/s41592-020-0953-2","article-title":"An optimized acetylcholine sensor for monitoring in vivo cholinergic activity","volume":"17","author":"Jing","year":"2020","journal-title":"Nat. Methods"},{"key":"10.1016\/j.celrep.2025.116555_bib38","doi-asserted-by":"crossref","first-page":"8445","DOI":"10.1523\/JNEUROSCI.23-24-08445.2003","article-title":"\u03b1-Conotoxin PIA Is Selective for \u03b16 Subunit-Containing Nicotinic Acetylcholine Receptors","volume":"23","author":"Dowell","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib39","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1124\/mol.65.4.944","article-title":"Analogs of \u03b1-conotoxin MII are selective for \u03b16-containing nicotinic acetylcholine receptors","volume":"65","author":"McIntosh","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.celrep.2025.116555_bib40","doi-asserted-by":"crossref","first-page":"2158","DOI":"10.1038\/sj.npp.1301617","article-title":"\u03b16-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens","volume":"33","author":"Exley","year":"2008","journal-title":"Neuropsychopharmacol"},{"key":"10.1016\/j.celrep.2025.116555_bib41","doi-asserted-by":"crossref","first-page":"3925","DOI":"10.1038\/ncomms4925","article-title":"Modulation of dopamine release in the striatum by physiologically relevant levels of nicotine","volume":"5","author":"Wang","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2025.116555_bib42","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/nature04708","article-title":"Recent advances in Cys-loop receptor structure and function","volume":"440","author":"Sine","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.116555_bib43","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.tips.2009.12.005","article-title":"Binding, activation and modulation of Cys-loop receptors","volume":"31","author":"Miller","year":"2010","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.celrep.2025.116555_bib44","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/S0022-3565(24)37322-7","article-title":"Strychnine: a potent competitive antagonist of \u03b1-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons","volume":"284","author":"Matsubayashi","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.celrep.2025.116555_bib45","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1124\/mol.55.2.248","article-title":"The \u03b19 nicotinic acetylcholine receptor shares pharmacological properties with type a \u03b3-aminobutyric acid, glycine, and type 3 serotonin receptors","volume":"55","author":"Rothlin","year":"1999","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.celrep.2025.116555_bib46","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/S0028-3908(01)00137-X","article-title":"Inhibition of nicotinic acetylcholine receptors by bicuculline","volume":"41","author":"Demuro","year":"2001","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.celrep.2025.116555_bib47","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1097\/00001756-200408260-00027","article-title":"Picrotoxin-mediated antagonism of \u03b13\u03b24 and \u03b17 acetylcholine receptors","volume":"15","author":"Erkkila","year":"2004","journal-title":"Neuroreport"},{"key":"10.1016\/j.celrep.2025.116555_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/aap.12016","article-title":"Selectivity of antagonists for the Cys-loop native receptors for ACh, 5-HT and GABA in guinea-pig myenteric neurons","volume":"34","author":"Ju\u00e1rez","year":"2014","journal-title":"Auton. Autacoid Pharmacol."},{"key":"10.1016\/j.celrep.2025.116555_bib49","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/S0026-895X(25)09869-4","article-title":"gamma-Aminobutyric acid type A receptor antagonists picrotoxin and bicuculline alter acetylcholine channel kinetics in cultured embryonic rat skeletal muscle","volume":"46","author":"Liu","year":"1994","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.celrep.2025.116555_bib50","doi-asserted-by":"crossref","first-page":"14463","DOI":"10.1523\/JNEUROSCI.2321-14.2014","article-title":"Mechanisms underlying desynchronization of cholinergic-evoked thalamic network activity","volume":"34","author":"Pita-Almenar","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib51","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/34413","article-title":"Acetylcholine receptors containing the \u03b22 subunit are involved in the reinforcing properties of nicotine","volume":"391","author":"Picciotto","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.116555_bib52","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1523\/JNEUROSCI.21-05-01452.2001","article-title":"Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei","volume":"21","author":"Klink","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib53","doi-asserted-by":"crossref","first-page":"8785","DOI":"10.1523\/JNEUROSCI.22-20-08785.2002","article-title":"Identification of the Nicotinic Receptor Subtypes Expressed on Dopaminergic Terminals in the Rat Striatum","volume":"22","author":"Zoli","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib54","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/jemt.10028","article-title":"Pharmacological properties of nicotinic acetylcholine receptors in isolated Locusta migratoria neurones","volume":"56","author":"Jackson","year":"2002","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.celrep.2025.116555_bib55","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1523\/JNEUROSCI.3908-07.2008","article-title":"Differential Tonic GABA Conductances in Striatal Medium Spiny Neurons","volume":"28","author":"Ade","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib56","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/s41583-023-00724-7","article-title":"GABA tone regulation and its cognitive functions in the brain","volume":"24","author":"Koh","year":"2023","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib57","article-title":"GABAergic regulation of striatal spiny projection neurons depends upon their activity state","volume":"22","author":"Day","year":"2024","journal-title":"PLoS Biol."},{"key":"10.1016\/j.celrep.2025.116555_bib58","doi-asserted-by":"crossref","first-page":"5113","DOI":"10.1038\/s41467-020-18882-y","article-title":"Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner","volume":"11","author":"Dorst","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2025.116555_bib59","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0361-9230(88)90244-4","article-title":"Dopamine-acetylcholine interaction in the rat striatum: A dual-labeling immunocytochemical study","volume":"21","author":"Chang","year":"1988","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.celrep.2025.116555_bib60","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/cne.1345","article-title":"Presynaptic localisation of the nicotinic acetylcholine receptor \u03b22 subunit immunoreactivity in rat nigrostriatal dopaminergic neurones","volume":"439","author":"Jones","year":"2001","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.celrep.2025.116555_bib61","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1085\/jgp.22.5.649","article-title":"Electric impedance of the squid giant axon during activity","volume":"22","author":"Cole","year":"1939","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.celrep.2025.116555_bib62","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1113\/jphysiol.1970.sp009301","article-title":"Sodium and potassium conductance changes during a membrane action potential","volume":"211","author":"Bezanilla","year":"1970","journal-title":"J. Physiol."},{"key":"10.1016\/j.celrep.2025.116555_bib63","doi-asserted-by":"crossref","first-page":"5504","DOI":"10.1523\/JNEUROSCI.5493-07.2008","article-title":"Recurrent collateral connections of striatal medium spiny neurons are disrupted in models of Parkinson's Disease","volume":"28","author":"Taverna","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib64","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.neuron.2016.04.031","article-title":"Dopamine regulation of lateral inhibition between striatal neurons gates the stimulant actions of cocaine","volume":"90","author":"Dobbs","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116555_bib65","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/nature11466","article-title":"Dopaminergic neurons inhibit striatal output through non-canonical release of GABA","volume":"490","author":"Tritsch","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.116555_bib66","first-page":"188","article-title":"Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3","volume":"7","author":"W\u00f3jtowicz","year":"2013","journal-title":"Front. Neural Circ."},{"key":"10.1016\/j.celrep.2025.116555_bib67","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.neuron.2016.09.007","article-title":"Principles of synaptic organization of GABAergic interneurons in the striatum","volume":"92","author":"Straub","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116555_bib68","doi-asserted-by":"crossref","first-page":"4958","DOI":"10.1038\/s41467-020-18247-5","article-title":"GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model","volume":"11","author":"Roberts","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2025.116555_bib69","doi-asserted-by":"crossref","first-page":"8682","DOI":"10.1523\/JNEUROSCI.2411-08.2008","article-title":"Recurrent inhibitory network among striatal cholinergic interneurons","volume":"28","author":"Sullivan","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib70","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111531","article-title":"Cholinergic control of striatal GABAergic microcircuits","volume":"41","author":"Kocaturk","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2025.116555_bib71","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.neuron.2014.01.023","article-title":"Striatal cholinergic interneurons drive GABA release from dopamine terminals","volume":"82","author":"Nelson","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116555_bib72","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/nature11657","article-title":"Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning","volume":"492","author":"Brown","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.116555_bib73","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/nature08758","article-title":"Neural bases for addictive properties of benzodiazepines","volume":"463","author":"Tan","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2025.116555_bib74","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1124\/jpet.117.241802","article-title":"Diazepam concurrently increases the frequency and decreases the amplitude of transient dopamine release events in the nucleus accumbens","volume":"364","author":"Schelp","year":"2018","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.celrep.2025.116555_bib75","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1021\/acschemneuro.8b00268","article-title":"Local GABAA receptor-mediated suppression of dopamine release within the nucleus accumbens","volume":"10","author":"Brodnik","year":"2019","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib76","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.tins.2011.01.004","article-title":"Hooked on benzodiazepines: GABAA receptor subtypes and addiction","volume":"34","author":"Tan","year":"2011","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib77","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S0165-6147(97)90675-1","article-title":"The benzodiazepine binding site of GABAA receptors","volume":"18","author":"Sigel","year":"1997","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.celrep.2025.116555_bib78","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1471-4159.2004.02271.x","article-title":"Identification of GABAA receptor subunit variants in midbrain dopaminergic neurons","volume":"89","author":"Okada","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.celrep.2025.116555_bib79","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.neuropharm.2018.01.036","article-title":"GABAA receptor: Positive and negative allosteric modulators","volume":"136","author":"Olsen","year":"2018","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.celrep.2025.116555_bib80","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.cell.2018.07.028","article-title":"Molecular diversity and specializations among the cells of the adult mouse brain","volume":"174","author":"Saunders","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2025.116555_bib81","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.celrep.2012.05.011","article-title":"Selective activation of cholinergic interneurons enhances accumbal phasic dopamine release: setting the tone for reward processing","volume":"2","author":"Cachope","year":"2012","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2025.116555_bib82","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/s41583-022-00561-0","article-title":"Local modulation by presynaptic receptors controls neuronal communication and behaviour","volume":"23","author":"Lovinger","year":"2022","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib83","doi-asserted-by":"crossref","first-page":"7393","DOI":"10.1523\/JNEUROSCI.2137-12.2013","article-title":"Multiple sources of striatal inhibition are differentially affected in huntington's disease mouse models","volume":"33","author":"Cepeda","year":"2013","journal-title":"J. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib84","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/0006-8993(93)91459-6","article-title":"Differential effect of systemic administration of bromocriptine and l-DOPA on the release of acetylcholine from striatum of intact and 6-OHDA-treated rats","volume":"608","author":"DeBoer","year":"1993","journal-title":"Brain Res."},{"key":"10.1016\/j.celrep.2025.116555_bib85","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/nn1700","article-title":"RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion","volume":"9","author":"Ding","year":"2006","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2025.116555_bib86","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/j.neuron.2019.03.004","article-title":"Circuit mechanisms of Parkinson\u2019s Disease","volume":"101","author":"McGregor","year":"2019","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2025.116555_bib87","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adp6301","article-title":"Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA\u2013induced dyskinetic behaviors","volume":"10","author":"Nielsen","year":"2024","journal-title":"Sci. Adv."},{"key":"10.1016\/j.celrep.2025.116555_bib88","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1038\/s41593-022-01152-z","article-title":"Fiber photometry in striatum reflects primarily nonsomatic changes in calcium","volume":"25","author":"Legaria","year":"2022","journal-title":"Nat. Neurosci."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124725013269?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124725013269?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T12:48:39Z","timestamp":1790599719000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124725013269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":88,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S2211124725013269"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2025.116555","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.06.25.600616","asserted-by":"object"}]},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Presynaptic GABAA receptors control integration of nicotinic input onto dopaminergic axons in the striatum","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2025.116555","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116555"}}