{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T01:20:01Z","timestamp":1792545601299,"version":"4.5.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T00:00:00Z","timestamp":1767657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018541","name":"Science Fund for Distinguished Young Scholars of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20240018"],"award-info":[{"award-number":["BK20240018"]}],"id":[{"id":"10.13039\/501100018541","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173160"],"award-info":[{"award-number":["82173160"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82473415"],"award-info":[{"award-number":["82473415"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273301"],"award-info":[{"award-number":["82273301"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BE2020622"],"award-info":[{"award-number":["BE2020622"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.celrep.2026.116941","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T17:12:33Z","timestamp":1770138753000},"page":"116941","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer"],"prefix":"10.1016","volume":"45","author":[{"given":"Guanghui","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2421-7311","authenticated-orcid":false,"given":"Wei","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianlei","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghao","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongming","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongqing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyan","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihua","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenli","family":"Diao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongqian","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junlong","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2026.116941_bib1","first-page":"12","article-title":"Cancer statistics, 2024","volume":"74","author":"Siegel","year":"2024","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.celrep.2026.116941_bib2","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.eururo.2012.09.057","article-title":"ICUD-EAU International Consultation on Bladder Cancer 2012: Screening, diagnosis, and molecular markers","volume":"63","author":"Kamat","year":"2013","journal-title":"Eur. Urol."},{"key":"10.1016\/j.celrep.2026.116941_bib3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1200\/JCO.2011.37.3571","article-title":"Randomized phase II\/III trial assessing gemcitabine\/carboplatin and methotrexate\/carboplatin\/vinblastine in patients with advanced urothelial cancer who are unfit for cisplatin-based chemotherapy: EORTC study 30986","volume":"30","author":"De Santis","year":"2012","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.celrep.2026.116941_bib4","doi-asserted-by":"crossref","first-page":"4602","DOI":"10.1200\/JCO.2005.07.757","article-title":"Long-term survival results of a randomized trial comparing gemcitabine plus cisplatin, with methotrexate, vinblastine, doxorubicin, plus cisplatin in patients with bladder cancer","volume":"23","author":"von der Maase","year":"2005","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.celrep.2026.116941_bib5","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.ejphar.2014.07.025","article-title":"Cisplatin in cancer therapy: molecular mechanisms of action","volume":"740","author":"Dasari","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.celrep.2026.116941_bib6","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.cell.2012.06.013","article-title":"Cancer epigenetics: from mechanism to therapy","volume":"150","author":"Dawson","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.116941_bib7","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1158\/0008-5472.CAN-22-2233","article-title":"NAT10 Drives Cisplatin Chemoresistance by Enhancing ac4C-Associated DNA Repair in Bladder Cancer","volume":"83","author":"Xie","year":"2023","journal-title":"Cancer Res."},{"key":"10.1016\/j.celrep.2026.116941_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.drup.2023.100938","article-title":"Regulation of cisplatin resistance in bladder cancer by epigenetic mechanisms","volume":"68","author":"Li","year":"2023","journal-title":"Drug Resist. Updat."},{"key":"10.1016\/j.celrep.2026.116941_bib9","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/s41392-022-01151-3","article-title":"Lactate metabolism in human health and disease","volume":"7","author":"Li","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.celrep.2026.116941_bib10","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/s41586-019-1678-1","article-title":"Metabolic regulation of gene expression by histone lactylation","volume":"574","author":"Zhang","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.116941_bib11","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/s42255-022-00710-w","article-title":"Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma","volume":"5","author":"Yang","year":"2023","journal-title":"Nat. Metab."},{"key":"10.1016\/j.celrep.2026.116941_bib12","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202400227","article-title":"Integrated Lactylome Characterization Reveals the Molecular Dynamics of Protein Regulation in Gastrointestinal Cancers","volume":"11","author":"Duan","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.celrep.2026.116941_bib13","doi-asserted-by":"crossref","first-page":"6523","DOI":"10.1038\/s41467-023-42025-8","article-title":"Lactylation of METTL16 promotes cuproptosis via m(6)A-modification on FDX1 mRNA in gastric cancer","volume":"14","author":"Sun","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.116941_bib14","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2314128121","article-title":"KAT8-catalyzed lactylation promotes eEF1A2-mediated protein synthesis and colorectal carcinogenesis","volume":"121","author":"Xie","year":"2024","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.116941_bib15","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.jhep.2024.04.010","article-title":"Nucleolin lactylation contributes to intrahepatic cholangiocarcinoma pathogenesis via RNA splicing regulation of MADD","volume":"81","author":"Yang","year":"2024","journal-title":"J. Hepatol."},{"key":"10.1016\/j.celrep.2026.116941_bib16","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1158\/0008-5472.CAN-24-1412","article-title":"PTBP1 Lactylation Promotes Glioma Stem Cell Maintenance through PFKFB4-Driven Glycolysis","volume":"85","author":"Zhou","year":"2024","journal-title":"Cancer Res."},{"key":"10.1016\/j.celrep.2026.116941_bib17","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1016\/j.cell.2024.04.002","article-title":"Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis","volume":"187","author":"Zong","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.116941_bib18","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.urolonc.2007.05.006","article-title":"RhoGDI2: a new metastasis suppressor gene: discovery and clinical translation","volume":"25","author":"Harding","year":"2007","journal-title":"Urol. Oncol."},{"key":"10.1016\/j.celrep.2026.116941_bib19","doi-asserted-by":"crossref","first-page":"3800","DOI":"10.1158\/1078-0432.CCR-03-0653","article-title":"Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer","volume":"10","author":"Theodorescu","year":"2004","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.celrep.2026.116941_bib20","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abi6696","article-title":"Class I histone deacetylases (HDAC1-3) are histone lysine delactylases","volume":"8","author":"Moreno-Yruela","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.celrep.2026.116941_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2024.110911","article-title":"Sirtuin 1\/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis","volume":"27","author":"Du","year":"2024","journal-title":"iScience"},{"key":"10.1016\/j.celrep.2026.116941_bib22","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1517\/14728220903449251","article-title":"RhoGDI2 as a therapeutic target in cancer","volume":"14","author":"Cho","year":"2010","journal-title":"Expert Opin. Ther. Targets"},{"key":"10.1016\/j.celrep.2026.116941_bib23","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1038\/onc.2012.124","article-title":"PKC\u03b1 phosphorylation of RhoGDI2 at Ser31 disrupts interactions with Rac1 and decreases GDI activity","volume":"32","author":"Griner","year":"2013","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2026.116941_bib24","doi-asserted-by":"crossref","first-page":"5807","DOI":"10.1073\/pnas.0810094106","article-title":"Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function","volume":"106","author":"Wu","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.116941_bib25","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1158\/2159-8290.CD-23-0437","article-title":"GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress","volume":"14","author":"Zhou","year":"2024","journal-title":"Cancer Discov."},{"key":"10.1016\/j.celrep.2026.116941_bib26","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1016\/j.juro.2017.12.062","article-title":"Neoadjuvant Dose Dense MVAC versus Gemcitabine and Cisplatin in Patients with cT3-4aN0M0 Bladder Cancer Treated with Radical Cystectomy","volume":"199","author":"Zargar","year":"2018","journal-title":"J. Urol."},{"key":"10.1016\/j.celrep.2026.116941_bib27","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1038\/onc.2011.384","article-title":"Molecular mechanisms of cisplatin resistance","volume":"31","author":"Galluzzi","year":"2012","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2026.116941_bib28","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nature14328","article-title":"REV7 counteracts DNA double-strand break resection and affects PARP inhibition","volume":"521","author":"Xu","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.116941_bib29","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1016\/j.cell.2013.05.023","article-title":"53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions","volume":"153","author":"Callen","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.116941_bib30","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.cellsig.2018.01.004","article-title":"Oncogenic RAC1 and NRAS drive resistance to endoplasmic reticulum stress through MEK\/ERK signalling","volume":"44","author":"Bright","year":"2018","journal-title":"Cell. Signal."},{"key":"10.1016\/j.celrep.2026.116941_bib31","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.tig.2021.09.009","article-title":"Histone lactylation: epigenetic mark of glycolytic switch","volume":"38","author":"Dai","year":"2022","journal-title":"Trends Genet."},{"key":"10.1016\/j.celrep.2026.116941_bib32","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s13059-021-02308-z","article-title":"Histone lactylation drives oncogenesis by facilitating m(6)A reader protein YTHDF2 expression in ocular melanoma","volume":"22","author":"Yu","year":"2021","journal-title":"Genome Biol."},{"key":"10.1016\/j.celrep.2026.116941_bib33","doi-asserted-by":"crossref","first-page":"2273","DOI":"10.1093\/nar\/gkad1193","article-title":"Histone lactylation-boosted ALKBH3 potentiates tumor progression and diminished promyelocytic leukemia protein nuclear condensates by m1A demethylation of SP100A","volume":"52","author":"Gu","year":"2024","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2026.116941_bib34","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2421496121","article-title":"DPF2 reads histone lactylation to drive transcription and tumorigenesis","volume":"121","author":"Zhai","year":"2024","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.116941_bib35","doi-asserted-by":"crossref","first-page":"3561","DOI":"10.1038\/s41467-024-47900-6","article-title":"HBO1 catalyzes lysine lactylation and mediates histone H3K9la to regulate gene transcription","volume":"15","author":"Niu","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.116941_bib36","article-title":"Metabolic Recoding of NSUN2-Mediated m(5)C Modification Promotes the Progression of Colorectal Cancer via the NSUN2\/YBX1\/m(5)C-ENO1 Positive Feedback Loop","volume":"11","author":"Chen","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.celrep.2026.116941_bib37","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202401399","article-title":"Lactylation-Driven IGF2BP3-Mediated Serine Metabolism Reprogramming and RNA m6A-Modification Promotes Lenvatinib Resistance in HCC","volume":"11","author":"Lu","year":"2024","journal-title":"Adv. Sci."},{"key":"10.1016\/j.celrep.2026.116941_bib38","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/j.molcel.2022.02.033","article-title":"Lactylation-driven METTL3-mediated RNA m(6)A modification promotes immunosuppression of tumor-infiltrating myeloid cells","volume":"82","author":"Xiong","year":"2022","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.116941_bib39","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1093\/procel\/pwae052","article-title":"PDHX acetylation facilitates tumor progression by disrupting PDC assembly and activating lactylation mediated gene expression","volume":"16","author":"Jiang","year":"2025","journal-title":"Protein Cell"},{"key":"10.1016\/j.celrep.2026.116941_bib40","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/s12943-021-01369-9","article-title":"KDM6A-ARHGDIB axis blocks metastasis of bladder cancer by inhibiting Rac1","volume":"20","author":"Liu","year":"2021","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.celrep.2026.116941_bib41","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.cell.2023.11.022","article-title":"Metabolic regulation of homologous recombination repair by MRE11 lactylation","volume":"187","author":"Chen","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.116941_bib42","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/s41586-024-07620-9","article-title":"NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance","volume":"631","author":"Chen","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.116941_bib43","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1016\/j.cmet.2024.07.011","article-title":"Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma","volume":"36","author":"Li","year":"2024","journal-title":"Cell Metab."},{"key":"10.1016\/j.celrep.2026.116941_bib44","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/s41586-023-05838-7","article-title":"RHOJ controls EMT-associated resistance to chemotherapy","volume":"616","author":"Debaugnies","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.116941_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2024.101928","article-title":"Efficacy and delivery strategies of the dual Rac\/Cdc42 inhibitor MBQ-167 in HER2 overexpressing breast cancer","volume":"44","author":"Vel\u00e1zquez-Vega","year":"2024","journal-title":"Transl. Oncol."},{"key":"10.1016\/j.celrep.2026.116941_bib46","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1158\/1535-7163.MCT-21-0348","article-title":"Efficacy of Rac and Cdc42 Inhibitor MBQ-167 in Triple-negative Breast Cancer","volume":"20","author":"Cruz-Collazo","year":"2021","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.celrep.2026.116941_bib47","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1038\/nsmb.1899","article-title":"Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining","volume":"17","author":"Miller","year":"2010","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.celrep.2026.116941_bib48","doi-asserted-by":"crossref","first-page":"4644","DOI":"10.1158\/1078-0432.CCR-23-1795","article-title":"Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair","volume":"29","author":"Solta","year":"2023","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.celrep.2026.116941_bib49","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1038\/s43018-024-00729-w","article-title":"Entinostat, nivolumab and ipilimumab for women with advanced HER2-negative breast cancer: a phase Ib trial","volume":"5","author":"Roussos Torres","year":"2024","journal-title":"Nat. Cancer"},{"key":"10.1016\/j.celrep.2026.116941_bib50","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.1200\/JCO.21.00944","article-title":"E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor-Positive Advanced Breast Cancer. A Trial of the ECOG-ACRIN Cancer Research Group","volume":"39","author":"Connolly","year":"2021","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.celrep.2026.116941_bib51","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1016\/j.molcel.2025.06.019","article-title":"Lactylation of XLF promotes non-homologous end-joining repair and chemoresistance in cancer","volume":"85","author":"Jin","year":"2025","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.116941_bib52","doi-asserted-by":"crossref","first-page":"4141","DOI":"10.1038\/s41467-022-31783-6","article-title":"Lysosomal protein transmembrane 5 promotes lung-specific metastasis by regulating BMPR1A lysosomal degradation","volume":"13","author":"Jiang","year":"2022","journal-title":"Nat. Commun."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726000197?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726000197?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T05:00:52Z","timestamp":1777093252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124726000197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S2211124726000197"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2026.116941","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2026.116941","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"116941"}}