{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T05:00:50Z","timestamp":1790312450006,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007922","name":"International Spinal Research Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007922","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014013","name":"UK Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"UK Research and Innovation Medical Research Council","doi-asserted-by":"publisher","award":["MR\/X006867\/1"],"award-info":[{"award-number":["MR\/X006867\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"UK Research and Innovation Medical Research Council","doi-asserted-by":"publisher","award":["MR\/P008658\/1"],"award-info":[{"award-number":["MR\/P008658\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.celrep.2026.117399","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T21:28:38Z","timestamp":1779830918000},"page":"117399","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth"],"prefix":"10.1016","volume":"45","author":[{"given":"George M.","family":"Gibbons","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Fuchsberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Abdelgawad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano L.","family":"Giandomenico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Korn\u00e9lia","family":"Szeb\u00e9nyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veselina","family":"Petrova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lea M.D.","family":"Wenger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel N.","family":"Olschewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremi","family":"Chabros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Muresan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachael C.","family":"Feord","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Asif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Fawcett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanna B.","family":"Mierau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Paulsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madeline A.","family":"Lancaster","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1301-2292","authenticated-orcid":false,"given":"Andr\u00e1s","family":"Lakatos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2026.117399_bib1","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ydbio.2017.09.034","article-title":"Salamander spinal cord regeneration: The ultimate positive control in vertebrate spinal cord regeneration","volume":"432","author":"Tazaki","year":"2017","journal-title":"Dev. Biol."},{"key":"10.1016\/j.celrep.2026.117399_bib2","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1038\/nrg1923","article-title":"Bridging the regeneration gap: Genetic insights from diverse animal models","volume":"7","author":"S\u00e1nchez Alvarado","year":"2006","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.celrep.2026.117399_bib3","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1038\/nrn1326","article-title":"Regeneration beyond the glial scar","volume":"5","author":"Silver","year":"2004","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib4","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1126\/science.1067840","article-title":"Repairing the Injured Spinal Cord","volume":"295","author":"Schwab","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.117399_bib5","article-title":"Revisiting Long-Distance Axon Growth Ability in the Developing Spinal Cord using a Novel Lesion Paradigm","author":"Ruven","year":"2022","journal-title":"bioRxiv"},{"key":"10.1016\/j.celrep.2026.117399_bib6","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1002\/neu.20224","article-title":"Changes within maturing neurons limit axonal regeneration in the developing spinal cord","volume":"66","author":"Blackmore","year":"2006","journal-title":"J. Neurobiol."},{"key":"10.1016\/j.celrep.2026.117399_bib7","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/cne.902820304","article-title":"Extension of the critical period for developmental plasticity of the corticospinal pathway","volume":"282","author":"Bregman","year":"1989","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.celrep.2026.117399_bib8","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2023.1198041","article-title":"Moving CNS axon growth and regeneration research into human model systems","volume":"17","author":"Lear","year":"2023","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib9","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/s41583-024-00849-3","article-title":"Neuronal maturation and axon regeneration: unfixing circuitry to enable repair","volume":"25","author":"Hilton","year":"2024","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib10","doi-asserted-by":"crossref","DOI":"10.1126\/science.1247125","article-title":"Organogenesis in a dish: Modeling development and disease using organoid technologies","volume":"345","author":"Lancaster","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.117399_bib11","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/s41593-019-0350-2","article-title":"Cerebral organoids at the air\u2013liquid interface generate diverse nerve tracts with functional output","volume":"22","author":"Giandomenico","year":"2019","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib12","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1016\/j.cell.2020.11.017","article-title":"Generation of Functional Human 3D Cortico-Motor Assembloids","volume":"183","author":"Andersen","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117399_bib13","doi-asserted-by":"crossref","DOI":"10.1242\/dev.162214","article-title":"Three-dimensional induction of dorsal, intermediate and ventral spinal cord tissues from human pluripotent stem cells","volume":"145","author":"Ogura","year":"2018","journal-title":"Development"},{"key":"10.1016\/j.celrep.2026.117399_bib14","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/373344a0","article-title":"Developing motor neurons rescued from programmed and axotomy-induced cell death by gdnf","volume":"373","author":"Oppenheim","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117399_bib15","doi-asserted-by":"crossref","first-page":"E2486","DOI":"10.1073\/pnas.1615372114","article-title":"Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons","volume":"114","author":"Schaller","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.117399_bib16","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nbt.3049","article-title":"Combinatorial analysis of developmental cues efficiently converts human pluripotent stem cells into multiple neuronal subtypes","volume":"33","author":"Maury","year":"2015","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.celrep.2026.117399_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0053024","article-title":"Robust Formation and Maintenance of Continuous Stratified Cortical Neuroepithelium by Laminin-Containing Matrix in Mouse ES Cell Culture","volume":"7","author":"Nasu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.celrep.2026.117399_bib18","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/nature12517","article-title":"Cerebral organoids model human brain development and microcephaly","volume":"501","author":"Lancaster","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117399_bib19","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1038\/s41593-021-00923-4","article-title":"Human ALS\/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology","volume":"24","author":"Szeb\u00e9nyi","year":"2021","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib20","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1038\/s41593-023-01311-w","article-title":"Single-cell transcriptomic landscape of the developing human spinal cord","volume":"26","author":"Andersen","year":"2023","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib21","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1146\/annurev.ne.18.030195.002433","article-title":"The Role of the Floor Plate in Axon Guidance","volume":"18","author":"Colamarino","year":"1995","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib22","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00401-009-0624-y","article-title":"Ependymal cells: Biology and pathology","volume":"119","author":"Del Bigio","year":"2010","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.celrep.2026.117399_bib23","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.neuron.2023.01.007","article-title":"A cellular taxonomy of the adult human spinal cord","volume":"111","author":"Yadav","year":"2023","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2026.117399_bib24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1083\/jcb.201605101","article-title":"Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits","volume":"214","author":"Zhou","year":"2016","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117399_bib25","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.stem.2019.12.007","article-title":"Self-Organizing 3D Human Trunk Neuromuscular Organoids","volume":"26","author":"Faustino Martins","year":"2020","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.celrep.2026.117399_bib26","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/S0896-6273(01)00544-X","article-title":"Assigning the positional identity of spinal motor neurons: Rostrocaudal patterning of Hox-c expression by FGFs, Gdf11, and retinoids","volume":"32","author":"Liu","year":"2001","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2026.117399_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2017.18","article-title":"Traumatic spinal cord injury","volume":"3","author":"Ahuja","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.celrep.2026.117399_bib28","article-title":"Amyotrophic lateral sclerosis","volume":"3","author":"Hardiman","year":"2017","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.celrep.2026.117399_bib29","doi-asserted-by":"crossref","first-page":"4744","DOI":"10.1038\/s41467-021-24776-4","article-title":"Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions","volume":"12","author":"Pereira","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117399_bib30","doi-asserted-by":"crossref","first-page":"4969","DOI":"10.1073\/pnas.1608254114","article-title":"Differentiation of V2a interneurons from human pluripotent stem cells","volume":"114","author":"Butts","year":"2017","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.117399_bib31","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/mus.20333","article-title":"Comparing the function of the corticospinal system in different species: Organizational differences for motor specialization?","volume":"32","author":"Lemon","year":"2005","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.celrep.2026.117399_bib32","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/nature22047","article-title":"Cell diversity and network dynamics in photosensitive human brain organoids","volume":"545","author":"Quadrato","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117399_bib33","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1016\/j.stem.2021.05.004","article-title":"Mapping human brain organoids on a spatial atlas","volume":"28","author":"Miura","year":"2021","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.celrep.2026.117399_bib34","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/s41593-021-00802-y","article-title":"Long-term maturation of human cortical organoids matches key early postnatal transitions","volume":"24","author":"Gordon","year":"2021","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib35","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.neuron.2016.09.026","article-title":"The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS","volume":"92","author":"Tedeschi","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2026.117399_bib36","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1002\/dneu.22605","article-title":"Developmental Chromatin Restriction of Pro-Growth Gene Networks Acts as an Epigenetic Barrier to Axon Regeneration in Cortical Neurons","volume":"78","author":"Venkatesh","year":"2018","journal-title":"Dev. Neurobiol."},{"key":"10.1016\/j.celrep.2026.117399_bib37","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.conb.2014.03.007","article-title":"Signaling regulations of neuronal regenerative ability","volume":"27","author":"Lu","year":"2014","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1016\/j.celrep.2026.117399_bib38","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1002\/cne.23580","article-title":"PTEN inhibition enhances neurite outgrowth in human embryonic stem cell-derived neuronal progenitor cells","volume":"522","author":"Wyatt","year":"2014","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.celrep.2026.117399_bib39","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1038\/nn.2603","article-title":"PTEN deletion enhances the regenerative ability of adult corticospinal neurons","volume":"13","author":"Liu","year":"2010","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib40","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1016\/j.neuron.2023.09.019","article-title":"Deep scRNA sequencing reveals a broadly applicable Regeneration Classifier and implicates antioxidant response in corticospinal axon regeneration","volume":"111","author":"Kim","year":"2023","journal-title":"Neuron"},{"key":"10.1016\/j.celrep.2026.117399_bib41","first-page":"31","article-title":"SnRPN controls the ability of neurons to regenerate axons","volume":"36","author":"Mertsch","year":"2018","journal-title":"Restor. Neurol. Neurosci."},{"key":"10.1016\/j.celrep.2026.117399_bib42","doi-asserted-by":"crossref","DOI":"10.1093\/braincomms\/fcz005","article-title":"Attenuating the DNA damage response to double-strand breaks restores function in models of CNS neurodegeneration","volume":"1","author":"Tuxworth","year":"2019","journal-title":"Brain Commun."},{"key":"10.1016\/j.celrep.2026.117399_bib43","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0015-0282(16)59349-2","article-title":"Combined (hormonal and microsurgical) therapy in infertile women with endometriosis","volume":"48","author":"Donnez","year":"1987","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.celrep.2026.117399_bib44","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0010-7824(75)90050-5","article-title":"The influence of hormonal contraceptives on sex hormone binding globulin (SHBG) capacity","volume":"11","author":"van Kammen","year":"1975","journal-title":"Contraception"},{"key":"10.1016\/j.celrep.2026.117399_bib45","doi-asserted-by":"crossref","first-page":"R61","DOI":"10.1186\/cc6887","article-title":"Improved outcomes from the administration of progesterone for patients with acute severe traumatic brain injury: A randomized controlled trial","volume":"12","author":"Xiao","year":"2008","journal-title":"Crit. Care"},{"key":"10.1016\/j.celrep.2026.117399_bib46","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.annemergmed.2006.07.932","article-title":"ProTECT: A Randomized Clinical Trial of Progesterone for Acute Traumatic Brain Injury","volume":"49","author":"Wright","year":"2007","journal-title":"Ann. Emerg. Med."},{"key":"10.1016\/j.celrep.2026.117399_bib47","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1038\/416636a","article-title":"Chondroitinase ABC promotes functional recovery after spinal cord injury","volume":"416","author":"Bradbury","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117399_bib48","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/s41596-023-00929-1","article-title":"Profiling human brain vascular cells using single-cell transcriptomics and organoids","volume":"19","author":"Crouch","year":"2024","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2026.117399_bib49","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1016\/j.cell.2023.04.022","article-title":"An in vivo neuroimmune organoid model to study human microglia phenotypes","volume":"186","author":"Schafer","year":"2023","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117399_bib50","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1089\/scd.2024.0231","article-title":"Leptomeningeal Neural Organoid Fusions as Models to Study Meninges-Brain Signaling","volume":"34","author":"Jones","year":"2025","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.celrep.2026.117399_bib51","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1016\/j.cell.2012.08.020","article-title":"Long-distance growth and connectivity of neural stem cells after severe spinal cord injury","volume":"150","author":"Lu","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117399_bib52","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1038\/s41586-020-2200-5","article-title":"Injured adult neurons regress to an embryonic transcriptional growth state","volume":"581","author":"Poplawski","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117399_bib53","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/sj.sc.3101328","article-title":"Repair of spinal cord injuries: Where are we, where are we going?","volume":"40","author":"Fawcett","year":"2002","journal-title":"Spinal Cord"},{"key":"10.1016\/j.celrep.2026.117399_bib54","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.201911674","article-title":"PI 3-kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS","volume":"12","author":"Nieuwenhuis","year":"2020","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.celrep.2026.117399_bib55","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.cell.2014.10.010","article-title":"IDISCO: A simple, rapid method to immunolabel large tissue samples for volume imaging","volume":"159","author":"Renier","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117399_bib56","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.77419","article-title":"EZ Clear for simple, rapid, and robust mouse whole organ clearing","volume":"11","author":"Hsu","year":"2022","journal-title":"eLife"},{"key":"10.1016\/j.celrep.2026.117399_bib57","article-title":"MEA-NAP: A flexible network analysis pipeline for neuronal 2D and 3D organoid multielectrode recordings","volume":"4","author":"Sit","year":"2024","journal-title":"Cell Rep. Methods"},{"key":"10.1016\/j.celrep.2026.117399_bib58","doi-asserted-by":"crossref","DOI":"10.3791\/51086-v","article-title":"Sample Drift Correction Following 4D Confocal Time-lapse Imaging","author":"Parslow","year":"2014","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.celrep.2026.117399_bib59","series-title":"Lecture Notes in Computer Science","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/978-3-540-24673-2_3","article-title":"High Accuracy Optical Flow Estimation Based on a Theory for Warping","author":"Brox","year":"2004"},{"key":"10.1016\/j.celrep.2026.117399_bib60","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1038\/s41467-017-01283-z","article-title":"A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models","volume":"8","author":"Tyzack","year":"2017","journal-title":"Nat. Commun."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726004778?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726004778?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T04:45:39Z","timestamp":1790311539000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124726004778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":60,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S2211124726004778"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2026.117399","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2026.117399","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117399"}}