{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:00:37Z","timestamp":1791234037253,"version":"4.1.0"},"reference-count":75,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T00:00:00Z","timestamp":1780358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2023YFA0913400"],"award-info":[{"award-number":["2023YFA0913400"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270643"],"award-info":[{"award-number":["32270643"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270581"],"award-info":[{"award-number":["32270581"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32230020"],"award-info":[{"award-number":["32230020"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007046","name":"Wuhan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007046","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022597","name":"Biofyzik\u00e1ln\u00ed \u00dastav, Akademie V\u011bd \u010cesk\u00e9 Republiky","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022597","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000148","name":"Canadian Anesthesiologists' Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000148","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.celrep.2026.117588","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T16:43:57Z","timestamp":1782146637000},"page":"117588","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["SPINDOC functions as a mitotic molecular counter to coordinate spatiotemporal CENP-A assembly"],"prefix":"10.1016","volume":"45","author":[{"given":"Zixu","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuechun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuting","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kehui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changrong","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqin","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhouliang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5623-6950","authenticated-orcid":false,"given":"Zan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiyan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2137-0783","authenticated-orcid":false,"given":"Guohong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2026.117588_bib1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/nrm.2015.5","article-title":"The molecular basis for centromere identity and function","volume":"17","author":"McKinley","year":"2016","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib2","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1038\/nrg2466","article-title":"Epigenetic regulation of centromeric chromatin: old dogs, new tricks?","volume":"9","author":"Allshire","year":"2008","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.celrep.2026.117588_bib3","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1126\/science.1206880","article-title":"Drosophila CENH3 is sufficient for centromere formation","volume":"334","author":"Mendiburo","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.117588_bib4","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nature09323","article-title":"The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres","volume":"467","author":"Sekulic","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117588_bib5","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.molcel.2006.12.018","article-title":"Centromere identity maintained by nucleosomes assembled with histone H3 containing the CENP-A targeting domain","volume":"25","author":"Black","year":"2007","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib6","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1038\/ncb2805","article-title":"A two-step mechanism for epigenetic specification of centromere identity and function","volume":"15","author":"Fachinetti","year":"2013","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib7","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1038\/nature02766","article-title":"Structural determinants for generating centromeric chromatin","volume":"430","author":"Black","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117588_bib8","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/nature10258","article-title":"Crystal structure of the human centromeric nucleosome containing CENP-A","volume":"476","author":"Tachiwana","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117588_bib9","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1101\/gad.259432.115","article-title":"Structural transitions of centromeric chromatin regulate the cell cycle-dependent recruitment of CENP-N","volume":"29","author":"Fang","year":"2015","journal-title":"Genes Dev."},{"key":"10.1016\/j.celrep.2026.117588_bib10","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1038\/cr.2018.13","article-title":"Molecular basis for CENP-N recognition of CENP-A nucleosome on the human kinetochore","volume":"28","author":"Tian","year":"2018","journal-title":"Cell Res."},{"key":"10.1016\/j.celrep.2026.117588_bib11","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/s41594-022-00758-y","article-title":"CENP-N promotes the compaction of centromeric chromatin","volume":"29","author":"Zhou","year":"2022","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib12","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1126\/science.aar2781","article-title":"Structural mechanisms of centromeric nucleosome recognition by the kinetochore protein CENP-N","volume":"359","author":"Chittori","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.117588_bib13","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/s41421-022-00439-6","article-title":"Structural insights into human CCAN complex assembled onto DNA","volume":"8","author":"Tian","year":"2022","journal-title":"Cell Discov."},{"key":"10.1016\/j.celrep.2026.117588_bib14","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202005099","article-title":"Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control","volume":"219","author":"Mitra","year":"2020","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib15","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1083\/jcb.151.5.1113","article-title":"Chromatin assembly at kinetochores is uncoupled from DNA replication","volume":"151","author":"Shelby","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib16","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1083\/jcb.200701066","article-title":"Propagation of centromeric chromatin requires exit from mitosis","volume":"176","author":"Jansen","year":"2007","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib17","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1083\/jcb.136.3.501","article-title":"Assembly of CENP-A into centromeric chromatin requires a cooperative array of nucleosomal DNA contact sites","volume":"136","author":"Shelby","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib18","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.devcel.2011.10.014","article-title":"Cdk activity couples epigenetic centromere inheritance to cell cycle progression","volume":"22","author":"Silva","year":"2012","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib19","doi-asserted-by":"crossref","first-page":"4046","DOI":"10.1038\/s41467-019-12019-6","article-title":"Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing","volume":"10","author":"Pan","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117588_bib20","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.cell.2009.02.040","article-title":"HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres","volume":"137","author":"Dunleavy","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib21","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.cell.2009.02.039","article-title":"Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP","volume":"137","author":"Foltz","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.devcel.2006.11.002","article-title":"Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1","volume":"12","author":"Fujita","year":"2007","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib23","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.molcel.2016.02.014","article-title":"Licensing of Centromeric Chromatin Assembly through the Mis18\u03b1-Mis18\u03b2 Heterotetramer","volume":"61","author":"Nardi","year":"2016","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib24","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1101\/gad.2045111","article-title":"Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP","volume":"25","author":"Hu","year":"2011","journal-title":"Genes Dev."},{"key":"10.1016\/j.celrep.2026.117588_bib25","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.devcel.2014.11.030","article-title":"Dynamic phosphorylation of CENP-A at Ser68 orchestrates its cell-cycle-dependent deposition at centromeres","volume":"32","author":"Yu","year":"2015","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib26","doi-asserted-by":"crossref","first-page":"13207","DOI":"10.1021\/jacs.6b05355","article-title":"Promiscuous Histone Mis-Assembly Is Actively Prevented by Chaperones","volume":"138","author":"Zhao","year":"2016","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.celrep.2026.117588_bib27","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1007\/s11427-021-2077-1","article-title":"Ser68 phosphoregulation is essential for CENP-A deposition, centromere function and viability in mice","volume":"65","author":"Liu","year":"2022","journal-title":"Sci. China Life Sci."},{"key":"10.1016\/j.celrep.2026.117588_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108388","article-title":"Essentiality of CENP-A Depends on Its Binding Mode to HJURP","volume":"33","author":"Hori","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2026.117588_bib29","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.devcel.2016.12.014","article-title":"CENP-A Modifications on Ser68 and Lys124 Are Dispensable for Establishment, Maintenance, and Long-Term Function of Human Centromeres","volume":"40","author":"Fachinetti","year":"2017","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib30","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.devcel.2016.12.015","article-title":"Ser68 Phosphorylation Ensures Accurate Cell-Cycle-Dependent CENP-A Deposition at Centromeres","volume":"40","author":"Wang","year":"2017","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib31","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1534\/genetics.113.149898","article-title":"A novel role of the N terminus of budding yeast histone H3 variant Cse4 in ubiquitin-mediated proteolysis","volume":"194","author":"Au","year":"2013","journal-title":"Genetics"},{"key":"10.1016\/j.celrep.2026.117588_bib32","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.molcel.2010.10.014","article-title":"Psh1 is an E3 ubiquitin ligase that targets the centromeric histone variant Cse4","volume":"40","author":"Hewawasam","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib33","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1016\/j.cub.2011.07.041","article-title":"The F box protein partner of paired regulates stability of Drosophila centromeric histone H3, CenH3(CID)","volume":"21","author":"Moreno-Moreno","year":"2011","journal-title":"Curr. Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib34","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.molcel.2010.09.025","article-title":"An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain","volume":"40","author":"Ranjitkar","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib35","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.devcel.2015.01.024","article-title":"CENP-A K124 Ubiquitylation Is Required for CENP-A Deposition at the Centromere","volume":"32","author":"Niikura","year":"2015","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109987","article-title":"Phosphorylation at Ser68 facilitates DCAF11-mediated ubiquitination and degradation of CENP-A during the cell cycle","volume":"37","author":"Wang","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2026.117588_bib37","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.02137","article-title":"The quantitative architecture of centromeric chromatin","volume":"3","author":"Bodor","year":"2014","journal-title":"eLife"},{"key":"10.1016\/j.celrep.2026.117588_bib38","first-page":"3511","article-title":"Overexpression and mistargeting of centromere protein-A in human primary colorectal cancer","volume":"63","author":"Tomonaga","year":"2003","journal-title":"Cancer Res."},{"key":"10.1016\/j.celrep.2026.117588_bib39","doi-asserted-by":"crossref","first-page":"46781","DOI":"10.18632\/oncotarget.18108","article-title":"Mislocalization of centromeric histone H3 variant CENP-A contributes to chromosomal instability (CIN) in human cells","volume":"8","author":"Shrestha","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.celrep.2026.117588_bib40","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1756-8935-8-2","article-title":"CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells","volume":"8","author":"Athwal","year":"2015","journal-title":"Epigenetics Chromatin"},{"key":"10.1016\/j.celrep.2026.117588_bib41","doi-asserted-by":"crossref","first-page":"3072","DOI":"10.1016\/j.cub.2019.07.052","article-title":"Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity","volume":"29","author":"Gemble","year":"2019","journal-title":"Curr. Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib42","doi-asserted-by":"crossref","first-page":"20808","DOI":"10.1074\/jbc.M117.814913","article-title":"A transcriptional coregulator, SPIN.DOC, attenuates the coactivator activity of Spindlin1","volume":"292","author":"Bae","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.celrep.2026.117588_bib43","doi-asserted-by":"crossref","first-page":"31861","DOI":"10.1073\/pnas.2007931117","article-title":"Driving integrative structural modeling with serial capture affinity purification","volume":"117","author":"Liu","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.117588_bib44","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.bbrc.2019.02.096","article-title":"Spindlin docking protein (SPIN.DOC) interaction with SPIN1 (a histone code reader) regulates Wnt signaling","volume":"511","author":"Devi","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.celrep.2026.117588_bib45","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/s41467-021-21236-x","article-title":"Structural mechanism of bivalent histone H3K4me3K9me3 recognition by the Spindlin1\/C11orf84 complex in rRNA transcription activation","volume":"12","author":"Du","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117588_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmb.2023.168371","article-title":"Molecular Basis for SPINDOC-Spindlin1 Engagement and Its Role in Transcriptional Attenuation","volume":"436","author":"Zhao","year":"2024","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib47","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/s41556-019-0331-4","article-title":"DNA replication acts as an error correction mechanism to maintain centromere identity by restricting CENP-A to centromeres","volume":"21","author":"Nechemia-Arbely","year":"2019","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib48","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.202007195","article-title":"CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity","volume":"220","author":"Shrestha","year":"2021","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib49","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1016\/j.celrep.2018.04.102","article-title":"Identification of Drivers of Aneuploidy in Breast Tumors","volume":"23","author":"Pfister","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2026.117588_bib50","doi-asserted-by":"crossref","first-page":"4340","DOI":"10.1038\/s41467-018-06545-y","article-title":"The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA","volume":"9","author":"Barra","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117588_bib51","doi-asserted-by":"crossref","first-page":"R72","DOI":"10.1186\/bcr3181","article-title":"Centromere protein-A, an essential centromere protein, is a prognostic marker for relapse in estrogen receptor-positive breast cancer","volume":"14","author":"McGovern","year":"2012","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.celrep.2026.117588_bib52","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.lungcan.2012.04.007","article-title":"Expression and prognostic significance of centromere protein A in human lung adenocarcinoma","volume":"77","author":"Wu","year":"2012","journal-title":"Lung Cancer"},{"key":"10.1016\/j.celrep.2026.117588_bib53","article-title":"Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy","volume":"7","author":"Zhang","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117588_bib54","doi-asserted-by":"crossref","first-page":"5218","DOI":"10.7150\/ijbs.85656","article-title":"CENPA functions as a transcriptional regulator to promote hepatocellular carcinoma progression via cooperating with YY1","volume":"19","author":"Liao","year":"2023","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.celrep.2026.117588_bib55","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1186\/s12967-021-03087-8","article-title":"CENPA promotes clear cell renal cell carcinoma progression and metastasis via Wnt\/\u03b2-catenin signaling pathway","volume":"19","author":"Wang","year":"2021","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.celrep.2026.117588_bib56","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1158\/1541-7786.MCR-21-0311","article-title":"Centromere Protein A Goes Far Beyond the Centromere in Cancers","volume":"20","author":"Liu","year":"2022","journal-title":"Mol. Cancer Res."},{"key":"10.1016\/j.celrep.2026.117588_bib57","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1016\/j.ccell.2018.03.007","article-title":"Genomic and Functional Approaches to Understanding Cancer Aneuploidy","volume":"33","author":"Taylor","year":"2018","journal-title":"Cancer Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib58","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.celrep.2018.03.076","article-title":"Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas","volume":"23","author":"Knijnenburg","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.celrep.2026.117588_bib59","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.cell.2019.08.052","article-title":"Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma","volume":"179","author":"Gao","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib60","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/msb.2010.58","article-title":"microRNA-122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma","volume":"6","author":"Burchard","year":"2010","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib61","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2012-000825","article-title":"Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study","volume":"2","author":"Liu","year":"2012","journal-title":"BMJ Open"},{"key":"10.1016\/j.celrep.2026.117588_bib62","doi-asserted-by":"crossref","first-page":"7385","DOI":"10.1158\/0008-5472.CAN-09-1089","article-title":"Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma","volume":"69","author":"Hoshida","year":"2009","journal-title":"Cancer Res."},{"key":"10.1016\/j.celrep.2026.117588_bib63","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/hep.21467","article-title":"Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets","volume":"45","author":"Boyault","year":"2007","journal-title":"Hepatology"},{"key":"10.1016\/j.celrep.2026.117588_bib64","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/978-1-4939-8961-4_20","article-title":"Mouse Model for Hepatocellular Carcinoma and Cholangiocarcinoma Originated from Mature Hepatocytes","volume":"1905","author":"Yamamoto","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib65","doi-asserted-by":"crossref","first-page":"3970","DOI":"10.1093\/hmg\/ddq312","article-title":"Centromere protein A dynamics in human pluripotent stem cell self-renewal, differentiation and DNA damage","volume":"19","author":"Ambartsumyan","year":"2010","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.celrep.2026.117588_bib66","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1073\/pnas.97.3.1148","article-title":"Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice","volume":"97","author":"Howman","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.117588_bib67","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/s41392-024-01767-7","article-title":"The two sides of chromosomal instability: drivers and brakes in cancer","volume":"9","author":"Hosea","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.celrep.2026.117588_bib68","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.devcel.2016.10.023","article-title":"Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression","volume":"39","author":"Funk","year":"2016","journal-title":"Dev. Cell"},{"key":"10.1016\/j.celrep.2026.117588_bib69","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1093\/nar\/gky1298","article-title":"Centromeric and ectopic assembly of CENP-A chromatin in health and cancer: old marks and new tracks","volume":"47","author":"Sharma","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2026.117588_bib70","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1101\/gad.348341.121","article-title":"Clonal selection of stable aneuploidies in progenitor cells drives high-prevalence tumorigenesis","volume":"35","author":"Trakala","year":"2021","journal-title":"Genes Dev."},{"key":"10.1016\/j.celrep.2026.117588_bib71","doi-asserted-by":"crossref","first-page":"D1211","DOI":"10.1093\/nar\/gky869","article-title":"iProX: an integrated proteome resource","volume":"47","author":"Ma","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2026.117588_bib72","doi-asserted-by":"crossref","first-page":"D1522","DOI":"10.1093\/nar\/gkab1081","article-title":"iProX in 2021: connecting proteomics data sharing with big data","volume":"50","author":"Chen","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2026.117588_bib73","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/s12915-018-0573-9","article-title":"UBN1\/2 of HIRA complex is responsible for recognition and deposition of H3.3 at cis-regulatory elements of genes in mouse ES cells","volume":"16","author":"Xiong","year":"2018","journal-title":"BMC Biol."},{"key":"10.1016\/j.celrep.2026.117588_bib74","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1016\/j.jhep.2022.11.017","article-title":"Decreased propionyl-CoA metabolism facilitates metabolic reprogramming and promotes hepatocellular carcinoma","volume":"78","author":"Sun","year":"2023","journal-title":"J. Hepatol."},{"key":"10.1016\/j.celrep.2026.117588_bib75","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1053\/j.gastro.2020.08.015","article-title":"Cooperation Between Distinct Cancer Driver Genes Underlies Intertumor Heterogeneity in Hepatocellular Carcinoma","volume":"159","author":"Molina-S\u00e1nchez","year":"2020","journal-title":"Gastroenterology"}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726006662?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726006662?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:33:48Z","timestamp":1791232428000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124726006662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":75,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S2211124726006662"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2026.117588","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SPINDOC functions as a mitotic molecular counter to coordinate spatiotemporal CENP-A assembly","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2026.117588","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117588"}}