{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:44:07Z","timestamp":1792100647230,"version":"4.4.0"},"reference-count":56,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T00:00:00Z","timestamp":1785888000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFC2501003"],"award-info":[{"award-number":["2021YFC2501003"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007835","name":"Wenzhou Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007835","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172882"],"award-info":[{"award-number":["82172882"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82320108016"],"award-info":[{"award-number":["82320108016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.celrep.2026.117892","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T15:22:13Z","timestamp":1787412133000},"page":"117892","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Acetate suppresses tumorigenesis through ACSS2-dependent H2A.Z acetylation in esophageal squamous cell carcinoma"],"prefix":"10.1016","volume":"45","author":[{"given":"Zhenhui","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenghao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangpeng","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhichao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuanxuan","family":"Gou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyan","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiangcong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhihua","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1054-6042","authenticated-orcid":false,"given":"Jianzhong","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2026.117892_bib1","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","article-title":"Hallmarks of cancer: the next generation","volume":"144","author":"Hanahan","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117892_bib2","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1158\/2159-8290.CD-21-1059","article-title":"Hallmarks of Cancer: New Dimensions","volume":"12","author":"Hanahan","year":"2022","journal-title":"Cancer Discov."},{"key":"10.1016\/j.celrep.2026.117892_bib3","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1002\/cac2.12374","article-title":"Crosstalk between metabolic reprogramming and epigenetics in cancer: updates on mechanisms and therapeutic opportunities","volume":"42","author":"Ge","year":"2022","journal-title":"Cancer Commun."},{"key":"10.1016\/j.celrep.2026.117892_bib4","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ccr.2012.06.008","article-title":"Cancer genetics and epigenetics: two sides of the same coin?","volume":"22","author":"You","year":"2012","journal-title":"Cancer Cell"},{"key":"10.1016\/j.celrep.2026.117892_bib5","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1146\/annurev-nutr-121415-112634","article-title":"Diet, Nutrition, and Cancer Epigenetics","volume":"36","author":"Sapienza","year":"2016","journal-title":"Annu. Rev. Nutr."},{"key":"10.1016\/j.celrep.2026.117892_bib6","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s40880-018-0302-3","article-title":"Metabolic recoding of epigenetics in cancer","volume":"38","author":"Wang","year":"2018","journal-title":"Cancer Commun."},{"key":"10.1016\/j.celrep.2026.117892_bib7","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s13238-021-00846-7","article-title":"Metabolic reprogramming and epigenetic modifications on the path to cancer","volume":"13","author":"Sun","year":"2022","journal-title":"Protein Cell"},{"key":"10.1016\/j.celrep.2026.117892_bib8","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.cell.2014.11.020","article-title":"Acetate Dependence of Tumors","volume":"159","author":"Comerford","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.117892_bib9","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.tcb.2019.05.005","article-title":"Acetate Metabolism in Physiology, Cancer, and Beyond","volume":"29","author":"Bose","year":"2019","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.celrep.2026.117892_bib10","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.trecan.2024.11.003","article-title":"Short-chain fatty acids and cancer","volume":"11","author":"Li","year":"2025","journal-title":"Trends Cancer"},{"key":"10.1016\/j.celrep.2026.117892_bib11","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ccell.2014.12.002","article-title":"Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress","volume":"27","author":"Schug","year":"2015","journal-title":"Cancer Cell"},{"key":"10.1016\/j.celrep.2026.117892_bib12","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1053\/j.gastro.2022.06.058","article-title":"Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer","volume":"163","author":"Zhou","year":"2022","journal-title":"Gastroenterology"},{"key":"10.1016\/j.celrep.2026.117892_bib13","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms11960","article-title":"Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia","volume":"7","author":"Gao","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117892_bib14","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.cmet.2018.12.019","article-title":"ACOT12-Dependent Alteration of Acetyl-CoA Drives Hepatocellular Carcinoma Metastasis by Epigenetic Induction of Epithelial-Mesenchymal Transition","volume":"29","author":"Lu","year":"2019","journal-title":"Cell Metab."},{"key":"10.1016\/j.celrep.2026.117892_bib15","doi-asserted-by":"crossref","first-page":"6677","DOI":"10.2147\/IJN.S135968","article-title":"Cationic lipid-based nanoparticles mediate functional delivery of acetate to tumor cells in vivo leading to significant anticancer effects","volume":"12","author":"Brody","year":"2017","journal-title":"Int. J. Nanomed."},{"key":"10.1016\/j.celrep.2026.117892_bib16","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2021.588466","article-title":"Acetate Induces Growth Arrest in Colon Cancer Cells Through Modulation of Mitochondrial Function","volume":"8","author":"Sahuri-Arisoylu","year":"2021","journal-title":"Front. Nutr."},{"key":"10.1016\/j.celrep.2026.117892_bib17","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1016\/j.jhep.2023.07.005","article-title":"Bifidobacterium pseudolongum-generated acetate suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma","volume":"79","author":"Song","year":"2023","journal-title":"J. Hepatol."},{"key":"10.1016\/j.celrep.2026.117892_bib18","unstructured":"Global burden of oesophageal and gastric cancer by histology and subsite in 2018, 2018, https:\/\/www.iarc.who.int\/news-events\/updated-estimates-of-the-global-burden-of-oesophageal-and-gastric-cancer-by-subtype-in-2018."},{"key":"10.1016\/j.celrep.2026.117892_bib19","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1053\/j.gastro.2022.05.054","article-title":"The Global Landscape of Esophageal Squamous Cell Carcinoma and Esophageal Adenocarcinoma Incidence and Mortality in 2020 and Projections to 2040: New Estimates From GLOBOCAN 2020","volume":"163","author":"Morgan","year":"2022","journal-title":"Gastroenterology"},{"key":"10.1016\/j.celrep.2026.117892_bib20","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.gie.2018.04.2352","article-title":"Screening for Esophageal Squamous Cell Carcinoma: Recent Advances","volume":"88","author":"Codipilly","year":"2018","journal-title":"Gastrointest. Endosc."},{"key":"10.1016\/j.celrep.2026.117892_bib21","doi-asserted-by":"crossref","DOI":"10.1136\/bmj-2023-074962","article-title":"Advances in diagnosis and management of cancer of the esophagus","volume":"385","author":"Deboever","year":"2024","journal-title":"BMJ"},{"key":"10.1016\/j.celrep.2026.117892_bib22","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/ng.2935","article-title":"Genomic and molecular characterization of esophageal squamous cell carcinoma","volume":"46","author":"Lin","year":"2014","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2026.117892_bib23","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1038\/s41422-020-0333-6","article-title":"Whole-genome sequencing of 508 patients identifies key molecular features associated with poor prognosis in esophageal squamous cell carcinoma","volume":"30","author":"Cui","year":"2020","journal-title":"Cell Res."},{"key":"10.1016\/j.celrep.2026.117892_bib24","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1038\/s41588-021-00928-6","article-title":"Mutational signatures in esophageal squamous cell carcinoma from eight countries with varying incidence","volume":"53","author":"Moody","year":"2021","journal-title":"Nat. Genet."},{"key":"10.1016\/j.celrep.2026.117892_bib25","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.ccell.2022.12.004","article-title":"Integrated multi-omics profiling yields a clinically relevant molecular classification for esophageal squamous cell carcinoma","volume":"41","author":"Liu","year":"2023","journal-title":"Cancer Cell"},{"key":"10.1016\/j.celrep.2026.117892_bib26","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/hep.32449","article-title":"Gut microbiota-derived short-chain fatty acids regulate group 3 innate lymphoid cells in HCC","volume":"77","author":"Hu","year":"2023","journal-title":"Hepatology"},{"key":"10.1016\/j.celrep.2026.117892_bib27","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1038\/s42255-024-01037-4","article-title":"Acetate reprogrammes tumour metabolism and promotes PD-L1 expression and immune evasion by upregulating c-Myc","volume":"6","author":"Wang","year":"2024","journal-title":"Nat. Metab."},{"key":"10.1016\/j.celrep.2026.117892_bib28","doi-asserted-by":"crossref","DOI":"10.1136\/gutjnl-2025-336025","article-title":"Bifidobacterium catenulatum boosts anti-PD-1 efficacy in microsatellite stable colorectal cancer via activating CD8+ T cells","author":"Li","year":"2026","journal-title":"Gut"},{"key":"10.1016\/j.celrep.2026.117892_bib29","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.molcel.2018.07.015","article-title":"Metabolic Signaling to the Nucleus in Cancer","volume":"71","author":"Campbell","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.117892_bib30","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/nrc.2016.87","article-title":"The metabolic fate of acetate in cancer","volume":"16","author":"Schug","year":"2016","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.117892_bib31","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/jso.24043","article-title":"Loss of ACSS2 expression predicts poor prognosis in patients with gastric cancer","volume":"112","author":"Hur","year":"2015","journal-title":"J. Surg. Oncol."},{"key":"10.1016\/j.celrep.2026.117892_bib32","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/modpathol.2016.172","article-title":"Downregulation of acetyl-CoA synthetase 2 is a metabolic hallmark of tumor progression and aggressiveness in colorectal carcinoma","volume":"30","author":"Bae","year":"2017","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.celrep.2026.117892_bib33","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/s12276-024-01185-3","article-title":"Acetyl-CoA synthetase 2 contributes to a better prognosis for liver cancer by switching acetate-glucose metabolism","volume":"56","author":"Jung","year":"2024","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.celrep.2026.117892_bib34","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1126\/science.123.3191.309","article-title":"On the origin of cancer cells","volume":"123","author":"Warburg","year":"1956","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.117892_bib35","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.15252\/embj.201696151","article-title":"Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine","volume":"36","author":"Zhang","year":"2017","journal-title":"EMBO J."},{"key":"10.1016\/j.celrep.2026.117892_bib36","doi-asserted-by":"crossref","DOI":"10.1111\/obr.70096","article-title":"Fueling Disease: ACSS2 in Obesity-Associated Metabolic Disorders and Cancer Progression","volume":"27","author":"Chen","year":"2026","journal-title":"Obes. Rev."},{"key":"10.1016\/j.celrep.2026.117892_bib37","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1038\/s43018-023-00636-6","article-title":"Acetate acts as a metabolic immunomodulator by bolstering T-cell effector function and potentiating antitumor immunity in breast cancer","volume":"4","author":"Miller","year":"2023","journal-title":"Nat. Cancer"},{"key":"10.1016\/j.celrep.2026.117892_bib38","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1053\/j.gastro.2020.06.050","article-title":"TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines","volume":"159","author":"Jiang","year":"2020","journal-title":"Gastroenterology"},{"key":"10.1016\/j.celrep.2026.117892_bib39","doi-asserted-by":"crossref","first-page":"4457","DOI":"10.1038\/s41467-021-24813-2","article-title":"Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis","volume":"12","author":"Ye","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117892_bib40","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1038\/s41417-024-00738-y","article-title":"Histone 3 lysine 9 acetylation-specific reprogramming regulates esophageal squamous cell carcinoma progression and metastasis","volume":"31","author":"Chen","year":"2024","journal-title":"Cancer Gene Ther."},{"key":"10.1016\/j.celrep.2026.117892_bib41","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1101\/gr.118919.110","article-title":"Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer","volume":"22","author":"Vald\u00e9s-Mora","year":"2012","journal-title":"Genome Res."},{"key":"10.1016\/j.celrep.2026.117892_bib42","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1038\/s41467-017-01393-8","article-title":"Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer","volume":"8","author":"Vald\u00e9s-Mora","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117892_bib43","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/s41419-021-03895-2","article-title":"H2A.Z acetylation by lincZNF337-AS1 via KAT5 implicated in the transcriptional misregulation in cancer signaling pathway in hepatocellular carcinoma","volume":"12","author":"Yuan","year":"2021","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.celrep.2026.117892_bib44","doi-asserted-by":"crossref","first-page":"15966","DOI":"10.1074\/jbc.M110.117069","article-title":"NuA4-dependent Acetylation of Nucleosomal Histones H4 and H2A Directly Stimulates Incorporation of H2A.Z by the SWR1 Complex","volume":"285","author":"Altaf","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.celrep.2026.117892_bib45","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s13072-019-0274-9","article-title":"The histone variant H2A","volume":"12","author":"Giaimo","year":"2019","journal-title":"Z in gene regulation Epigenetics & chromatin"},{"key":"10.1016\/j.celrep.2026.117892_bib46","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/s41467-023-36465-5","article-title":"Histone variant H2A.Z modulates nucleosome dynamics to promote DNA accessibility","volume":"14","author":"Li","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.celrep.2026.117892_bib47","doi-asserted-by":"crossref","first-page":"4627","DOI":"10.1016\/j.molcel.2022.11.002","article-title":"Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation","volume":"82","author":"Janas","year":"2022","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.117892_bib48","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/msb.2008.25","article-title":"Genomic analysis of estrogen cascade reveals histone variant H2A.Z associated with breast cancer progression","volume":"4","author":"Hua","year":"2008","journal-title":"Mol. Syst. Biol."},{"key":"10.1016\/j.celrep.2026.117892_bib49","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1756-8935-6-34","article-title":"Gene dysregulation by histone variant H2A.Z in bladder cancer","volume":"6","author":"Kim","year":"2013","journal-title":"Epigenetics Chromatin"},{"key":"10.1016\/j.celrep.2026.117892_bib50","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s10555-013-9486-9","article-title":"Histone H2A.Z deregulation in prostate cancer. Cause or effect?","volume":"33","author":"Dryhurst","year":"2014","journal-title":"Cancer Metastasis Rev."},{"key":"10.1016\/j.celrep.2026.117892_bib51","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1038\/s41586-019-1877-9","article-title":"H2A.Z facilitates licensing and activation of early replication origins","volume":"577","author":"Long","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117892_bib52","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1009125","article-title":"Effect of H2A.Z deletion is rescued by compensatory mutations in Fusarium graminearum","volume":"16","author":"Chen","year":"2020","journal-title":"PLoS Genet."},{"key":"10.1016\/j.celrep.2026.117892_bib53","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/s41586-020-03145-z","article-title":"Regulatory genomic circuitry of human disease loci by integrative epigenomics","volume":"590","author":"Boix","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.117892_bib54","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1038\/nprot.2017.124","article-title":"Chromatin-state discovery and genome annotation with ChromHMM","volume":"12","author":"Ernst","year":"2017","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.celrep.2026.117892_bib55","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/nbt.4096","article-title":"Integrating single-cell transcriptomic data across different conditions, technologies, and species","volume":"36","author":"Butler","year":"2018","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.celrep.2026.117892_bib56","doi-asserted-by":"crossref","first-page":"5291","DOI":"10.1038\/s41467-021-25539-x","article-title":"Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis","volume":"12","author":"Zhang","year":"2021","journal-title":"Nat. Commun."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726009708?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726009708?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:47:40Z","timestamp":1792097260000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124726009708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":56,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S2211124726009708"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2026.117892","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acetate suppresses tumorigenesis through ACSS2-dependent H2A.Z acetylation in esophageal squamous cell carcinoma","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2026.117892","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"117892"}}