{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:46:33Z","timestamp":1792010793398,"version":"4.4.0"},"reference-count":68,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020581","name":"AIRC Foundation for Cancer Research","doi-asserted-by":"publisher","award":["23820"],"award-info":[{"award-number":["23820"]}],"id":[{"id":"10.13039\/100020581","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005010","name":"Associazione Italiana per la Ricerca sul Cancro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005010","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004710","name":"Umberto Veronesi Foundation","doi-asserted-by":"publisher","award":["3916"],"award-info":[{"award-number":["3916"]}],"id":[{"id":"10.13039\/501100004710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Reports"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.celrep.2026.118145","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:24:44Z","timestamp":1791883484000},"page":"118145","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Untranslated region rewiring defines a novel class of oncogene fusions"],"prefix":"10.1016","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7778-5764","authenticated-orcid":false,"given":"Marina","family":"Cerqua","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9395-2240","authenticated-orcid":false,"given":"Estelle","family":"Bigot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4116-3354","authenticated-orcid":false,"given":"C\u00e9dric","family":"Chaveroux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo M.","family":"Comoglio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7153-4462","authenticated-orcid":false,"given":"Dogus M.","family":"Altintas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.celrep.2026.118145_bib1","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","article-title":"Hallmarks of cancer: the next generation","volume":"144","author":"Hanahan","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.118145_bib2","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/nrc3947","article-title":"The emerging complexity of gene fusions in cancer","volume":"15","author":"Mertens","year":"2015","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib3","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/nrc2091","article-title":"The impact of translocations and gene fusions on cancer causation","volume":"7","author":"Mitelman","year":"2007","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib4","article-title":"A functional genomic approach to actionable gene fusions for precision oncology","volume":"8","author":"Li","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.celrep.2026.118145_bib5","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/nrc1299","article-title":"A census of human cancer genes","volume":"4","author":"Futreal","year":"2004","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib6","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-71040-8","article-title":"Human transcription factor and protein kinase gene fusions in human cancer","volume":"10","author":"Salokas","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.celrep.2026.118145_bib7","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/nm.2673","article-title":"Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies","volume":"18","author":"Lipson","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.celrep.2026.118145_bib8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/s41392-025-02161-7","article-title":"Oncogenic gene fusions in cancer: from biology to therapy","volume":"10","author":"Liu","year":"2025","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.celrep.2026.118145_bib9","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/243290a0","article-title":"Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining","volume":"243","author":"Rowley","year":"1973","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.118145_bib10","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1126\/science.2406902","article-title":"Induction of chronic myelogenous leukemia in mice by the P210bcr\/abl gene of the Philadelphia chromosome","volume":"247","author":"Daley","year":"1990","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.118145_bib11","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/0092-8674(90)90659-3","article-title":"PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas","volume":"60","author":"Grieco","year":"1990","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.118145_bib12","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/nm.2644","article-title":"KIF5B-RET fusions in lung adenocarcinoma","volume":"18","author":"Kohno","year":"2012","journal-title":"Nat. Med."},{"key":"10.1016\/j.celrep.2026.118145_bib13","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1126\/science.267.5196.316.c","article-title":"Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma","volume":"267","author":"Morris","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.118145_bib14","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/nature05945","article-title":"Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer","volume":"448","author":"Soda","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.118145_bib15","first-page":"1565","article-title":"Analysis by pulsed field gel electrophoresis reveals complex rearrangements in two MET alleles in a chemically-treated human cell line, MNNG-HOS","volume":"5","author":"Testa","year":"1990","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2026.118145_bib16","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1158\/2159-8290.CD-24-0417","article-title":"Pan-Cancer Analysis of Oncogenic MET Fusions Reveals Distinct Pathogenomic Subsets with Differential Sensitivity to MET-Targeted Therapy","volume":"15","author":"Febres-Aldana","year":"2025","journal-title":"Cancer Discov."},{"key":"10.1016\/j.celrep.2026.118145_bib17","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1038\/nrm1261","article-title":"Met, metastasis, motility and more","volume":"4","author":"Birchmeier","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.celrep.2026.118145_bib18","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/nrc1912","article-title":"Invasive growth: a MET-driven genetic programme for cancer and stem cells","volume":"6","author":"Boccaccio","year":"2006","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib19","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/s41568-018-0002-y","article-title":"Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy","volume":"18","author":"Comoglio","year":"2018","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/nrc3205","article-title":"Targeting MET in cancer: rationale and progress","volume":"12","author":"Gherardi","year":"2012","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib21","doi-asserted-by":"crossref","first-page":"4275","DOI":"10.1038\/sj.onc.1202791","article-title":"Loss of the exon encoding the juxtamembrane domain is essential for the oncogenic activation of TPR-MET","volume":"18","author":"Vigna","year":"1999","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2026.118145_bib22","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.neo.2018.06.007","article-title":"Oncogenic Function of a KIF5B-MET Fusion Variant in Non-Small Cell Lung Cancer","volume":"20","author":"Gow","year":"2018","journal-title":"Neoplasia"},{"key":"10.1016\/j.celrep.2026.118145_bib23","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1158\/2159-8290.CD-24-1726","article-title":"Antitumor Activity of Vebreltinib and Characterization of Clinicogenomic Features in Solid Tumors with MET Rearrangements","volume":"15","author":"Nakazawa","year":"2025","journal-title":"Cancer Discov."},{"key":"10.1016\/j.celrep.2026.118145_bib24","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1158\/2159-8290.CD-17-0151","article-title":"AACR Project GENIE: Powering Precision Medicine through an International Consortium","volume":"7","year":"2017","journal-title":"Cancer Discov."},{"key":"10.1016\/j.celrep.2026.118145_bib25","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1126\/science.aad9868","article-title":"Translational control by 5'-untranslated regions of eukaryotic mRNAs","volume":"352","author":"Hinnebusch","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.118145_bib26","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/nature09322","article-title":"Genome-wide measurement of RNA secondary structure in yeast","volume":"467","author":"Kertesz","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.118145_bib27","doi-asserted-by":"crossref","first-page":"706","DOI":"10.15252\/embj.201592759","article-title":"Upstream ORFs are prevalent translational repressors in vertebrates","volume":"35","author":"Johnstone","year":"2016","journal-title":"Embo j"},{"key":"10.1016\/j.celrep.2026.118145_bib28","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkag234","article-title":"An expanded reference catalog of translated open reading frames for biomedical research","volume":"54","author":"Chothani","year":"2026","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2026.118145_bib29","doi-asserted-by":"crossref","DOI":"10.1038\/s44318-024-00338-4","article-title":"The integrated stress response drives MET oncogene overexpression in cancers","volume":"44","author":"Cerqua","year":"2025","journal-title":"Embo j"},{"key":"10.1016\/j.celrep.2026.118145_bib30","doi-asserted-by":"crossref","first-page":"7507","DOI":"10.1073\/pnas.0810916106","article-title":"Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans","volume":"106","author":"Calvo","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.118145_bib31","doi-asserted-by":"crossref","first-page":"2850","DOI":"10.1073\/pnas.83.9.2850","article-title":"Influences of mRNA secondary structure on initiation by eukaryotic ribosomes","volume":"83","author":"Kozak","year":"1986","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.118145_bib32","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1748-7188-6-26","article-title":"ViennaRNA Package 2.0","volume":"6","author":"Lorenz","year":"2011","journal-title":"Algorithms Mol. Biol."},{"key":"10.1016\/j.celrep.2026.118145_bib33","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/s41586-019-1186-3","article-title":"Next-generation characterization of the Cancer Cell Line Encyclopedia","volume":"569","author":"Ghandi","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.118145_bib34","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/s41568-024-00763-x","article-title":"The present and future of the Cancer Dependency Map","volume":"25","author":"Arafeh","year":"2025","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib35","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1126\/science.1846706","article-title":"Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product","volume":"251","author":"Bottaro","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.118145_bib36","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1038\/nrc779","article-title":"Scatter-factor and semaphorin receptors: cell signalling for invasive growth","volume":"2","author":"Trusolino","year":"2002","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib37","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.cmet.2018.08.006","article-title":"Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies","volume":"28","author":"Apicella","year":"2018","journal-title":"Cell Metab."},{"key":"10.1016\/j.celrep.2026.118145_bib38","doi-asserted-by":"crossref","first-page":"4672","DOI":"10.3390\/cancers15184672","article-title":"An Observatory for the MET Oncogene: A Guide for Targeted Therapies","volume":"15","author":"Altintas","year":"2023","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.celrep.2026.118145_bib39","first-page":"82","article-title":"Biology of MET: a double life between normal tissue repair and tumor progression","volume":"3","author":"Petrini","year":"2015","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.celrep.2026.118145_bib40","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S1097-2765(01)00378-1","article-title":"Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein","volume":"8","author":"Peschard","year":"2001","journal-title":"Mol. Cell"},{"key":"10.1016\/j.celrep.2026.118145_bib41","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1158\/1078-0432.CCR-21-1566","article-title":"FDA Approval Summary: Capmatinib and Tepotinib for the Treatment of Metastatic NSCLC Harboring MET Exon 14 Skipping Mutations or Alterations","volume":"28","author":"Mathieu","year":"2022","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.celrep.2026.118145_bib42","doi-asserted-by":"crossref","first-page":"7213","DOI":"10.1038\/sj.onc.1210522","article-title":"Oncogenic activation of the Met receptor tyrosine kinase fusion protein, Tpr-Met, involves exclusion from the endocytic degradative pathway","volume":"26","author":"Mak","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2026.118145_bib43","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1083\/jcb.119.3.629","article-title":"Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth","volume":"119","author":"Bussolino","year":"1992","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.celrep.2026.118145_bib44","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1093\/jnci\/djr093","article-title":"Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer","volume":"103","author":"De Bacco","year":"2011","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.celrep.2026.118145_bib45","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/ki.2013.102","article-title":"Activation of hepatocyte growth factor receptor, c-met, in renal tubules is required for renoprotection after acute kidney injury","volume":"84","author":"Zhou","year":"2013","journal-title":"Kidney Int."},{"key":"10.1016\/j.celrep.2026.118145_bib46","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/BF00204976","article-title":"Hepatocyte growth factor\/scatter factor-Met signaling in tumorigenicity and invasion\/metastasis","volume":"74","author":"Jeffers","year":"1996","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.celrep.2026.118145_bib47","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1016\/S1357-2725(99)00089-8","article-title":"HGF: a multifunctional growth factor controlling cell scattering","volume":"31","author":"Stella","year":"1999","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.celrep.2026.118145_bib48","doi-asserted-by":"crossref","first-page":"4046","DOI":"10.1073\/pnas.0509040103","article-title":"Structural basis of hepatocyte growth factor\/scatter factor and MET signalling","volume":"103","author":"Gherardi","year":"2006","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.celrep.2026.118145_bib49","first-page":"4277","article-title":"Scatter Factor\/Hepatocyte Growth Factor Protects against Cytotoxic Death in Human Glioblastoma via Phosphatidylinositol 3-Kinase- and AKT-dependent Pathways","volume":"60","author":"Bowers","year":"2000","journal-title":"Cancer Res."},{"key":"10.1016\/j.celrep.2026.118145_bib50","doi-asserted-by":"crossref","first-page":"4479","DOI":"10.1158\/1078-0432.CCR-05-0166","article-title":"Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation","volume":"11","author":"Lal","year":"2005","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.celrep.2026.118145_bib51","doi-asserted-by":"crossref","first-page":"8125","DOI":"10.1093\/nar\/15.20.8125","article-title":"An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs","volume":"15","author":"Kozak","year":"1987","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.celrep.2026.118145_bib52","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.21907","article-title":"Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress","volume":"6","author":"Tamarkin-Ben-Harush","year":"2017","journal-title":"eLife"},{"key":"10.1016\/j.celrep.2026.118145_bib53","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/s41388-022-02578-2","article-title":"Monitoring the 5\u2032UTR landscape reveals isoform switches to drive translational efficiencies in cancer","volume":"42","author":"Weber","year":"2023","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2026.118145_bib54","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1126\/science.1259037","article-title":"Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element","volume":"346","author":"Mansour","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.celrep.2026.118145_bib55","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1038\/nature08822","article-title":"The landscape of somatic copy-number alteration across human cancers","volume":"463","author":"Beroukhim","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.118145_bib56","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1038\/s41568-022-00488-9","article-title":"Structural variations in cancer and the 3D genome","volume":"22","author":"Dubois","year":"2022","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.celrep.2026.118145_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.gde.2024.102199","article-title":"Hijacked enhancer-promoter and silencer-promoter loops in cancer","volume":"86","author":"Wang","year":"2024","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.celrep.2026.118145_bib58","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/nature10912","article-title":"The translational landscape of mTOR signalling steers cancer initiation and metastasis","volume":"485","author":"Hsieh","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.celrep.2026.118145_bib59","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/j.cell.2018.08.039","article-title":"A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging","volume":"174","author":"Keren","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.celrep.2026.118145_bib60","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/s41587-021-00830-w","article-title":"Robust decomposition of cell type mixtures in spatial transcriptomics","volume":"40","author":"Cable","year":"2022","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.celrep.2026.118145_bib61","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1186\/1471-2164-13-220","article-title":"Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells","volume":"13","author":"Tebaldi","year":"2012","journal-title":"BMC Genom."},{"key":"10.1016\/j.celrep.2026.118145_bib62","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.gendis.2023.02.046","article-title":"Clinical and genomic analysis of baseline and acquired MET fusions with an intact kinase domain in lung cancer patients","volume":"11","author":"Jin","year":"2024","journal-title":"Genes Dis."},{"key":"10.1016\/j.celrep.2026.118145_bib63","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1093\/jnci\/djr103","article-title":"How scatter factor receptor c-MET contributes to tumor radioresistance: ready, set, scatter","volume":"103","author":"Guryanova","year":"2011","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.celrep.2026.118145_bib64","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1101\/gr.257246.119","article-title":"Accurate and efficient detection of gene fusions from RNA sequencing data","volume":"31","author":"Uhrig","year":"2021","journal-title":"Genome Res."},{"key":"10.1016\/j.celrep.2026.118145_bib65","doi-asserted-by":"crossref","DOI":"10.1093\/bib\/bbac519","article-title":"Recent advances in cancer fusion transcript detection","volume":"24","author":"Dorney","year":"2023","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.celrep.2026.118145_bib66","first-page":"2127","article-title":"c-fos mRNA instability determinants present within both the coding and the 3' non coding region link the degradation of this mRNA to its translation","volume":"11","author":"Veyrune","year":"1995","journal-title":"Oncogene"},{"key":"10.1016\/j.celrep.2026.118145_bib67","first-page":"5521","article-title":"Activation of the transforming potential of the human fos proto-oncogene requires message stabilization and results in increased amounts of partially modified fos protein","volume":"8","author":"Lee","year":"1988","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.celrep.2026.118145_bib68","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.1038\/s41467-022-29214-7","article-title":"eIF6 rebinding dynamically couples ribosome maturation and translation","volume":"13","author":"Jaako","year":"2022","journal-title":"Nat. Commun."}],"container-title":["Cell Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726012246?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211124726012246?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T20:05:58Z","timestamp":1792008358000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211124726012246"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":68,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S2211124726012246"],"URL":"https:\/\/doi.org\/10.1016\/j.celrep.2026.118145","relation":{},"ISSN":["2211-1247"],"issn-type":[{"value":"2211-1247","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Untranslated region rewiring defines a novel class of oncogene fusions","name":"articletitle","label":"Article Title"},{"value":"Cell Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.celrep.2026.118145","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"118145"}}