{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T11:30:51Z","timestamp":1790767851624,"version":"4.1.0"},"reference-count":85,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","geriatric.theclinics.com","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Geriatric Medicine"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.cger.2019.09.005","type":"journal-article","created":{"date-parts":[[2019,9,6]],"date-time":"2019-09-06T11:30:59Z","timestamp":1567769459000},"page":"119-130","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":77,"title":["Overview of Sleep and Circadian Rhythm Disorders in Parkinson Disease"],"prefix":"10.1016","volume":"36","author":[{"given":"Priti","family":"Gros","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandar","family":"Videnovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.cger.2019.09.005_bib1","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1002\/mds.20844","article-title":"International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: the NMSQuest study","volume":"21","author":"Chaudhuri","year":"2006","journal-title":"Mov Disord"},{"key":"10.1016\/j.cger.2019.09.005_bib2","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.parkreldis.2019.04.014","article-title":"Barriers to reporting non-motor symptoms to health-care providers in people with Parkinson's","volume":"64","author":"Hurt","year":"2019","journal-title":"Parkinsonism Relat Disord"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib3","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1136\/jnnp.66.4.431","article-title":"Influence of clinical and demographic variables on quality of life in patients with Parkinson's disease","volume":"66","author":"Karlsen","year":"1999","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.cger.2019.09.005_bib4","series-title":"The international classification of sleep disorders: diagnostic and coding manual","author":"American Academy of Sleep Medicine","year":"2014"},{"key":"10.1016\/j.cger.2019.09.005_bib5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.parkreldis.2016.09.010","article-title":"The course of insomnia in Parkinson's disease","volume":"33","author":"Zhu","year":"2016","journal-title":"Parkinsonism Relat Disord"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib6","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1212\/WNL.0000000000003540","article-title":"Changes in insomnia subtypes in early Parkinson disease","volume":"88","author":"Tholfsen","year":"2017","journal-title":"Neurology"},{"key":"10.1016\/j.cger.2019.09.005_bib7","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3389\/fneur.2017.00042","article-title":"The treatment of sleep disorders in Parkinson's disease: from research to clinical practice","volume":"8","author":"Loddo","year":"2017","journal-title":"Front Neurol"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib8","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.sleep.2005.03.011","article-title":"Progressive sleep 'destructuring' in Parkinson's disease. A polysomnographic study in 46 patients","volume":"6","author":"Diederich","year":"2005","journal-title":"Sleep Med"},{"issue":"7","key":"10.1016\/j.cger.2019.09.005_bib9","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.sleep.2013.03.010","article-title":"Subjectively impaired bed mobility in Parkinson disease affects sleep efficiency","volume":"14","author":"Louter","year":"2013","journal-title":"Sleep Med"},{"issue":"7","key":"10.1016\/j.cger.2019.09.005_bib10","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1002\/mds.20874","article-title":"Sleep complaints and their relation with drug treatment in patients suffering from Parkinson's disease","volume":"21","author":"Gomez-Esteban","year":"2006","journal-title":"Mov Disord"},{"issue":"5","key":"10.1016\/j.cger.2019.09.005_bib11","doi-asserted-by":"crossref","first-page":"487","DOI":"10.5664\/jcsm.27286","article-title":"Clinical guideline for the evaluation and management of chronic insomnia in adults","volume":"4","author":"Schutte-Rodin","year":"2008","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"16","key":"10.1016\/j.cger.2019.09.005_bib12","doi-asserted-by":"crossref","first-page":"2704","DOI":"10.1002\/mds.23190","article-title":"Scales to assess sleep impairment in Parkinson's disease: critique and recommendations","volume":"25","author":"Hogl","year":"2010","journal-title":"Mov Disord"},{"issue":"11","key":"10.1016\/j.cger.2019.09.005_bib13","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.5664\/jcsm.3150","article-title":"Insomnia and sleepiness in Parkinson disease: associations with symptoms and comorbidities","volume":"9","author":"Chung","year":"2013","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"3","key":"10.1016\/j.cger.2019.09.005_bib14","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1513\/AnnalsATS.201608-625OC","article-title":"Insomnia, sleep quality, and quality of life in mild to moderate Parkinson's disease","volume":"14","author":"Shafazand","year":"2017","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.cger.2019.09.005_bib15","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jns.2018.08.003","article-title":"Rotigotine transdermal patch for the treatment of neuropsychiatric symptoms in Parkinson's disease: a meta-analysis of randomized placebo-controlled trials","volume":"393","author":"Wang","year":"2018","journal-title":"J\u00a0Neurol Sci"},{"key":"10.1016\/j.cger.2019.09.005_bib16","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.sleep.2016.01.016","article-title":"Rotigotine may improve sleep architecture in Parkinson's disease: a double-blind, randomized, placebo-controlled polysomnographic study","volume":"21","author":"Pierantozzi","year":"2016","journal-title":"Sleep Med"},{"key":"10.1016\/j.cger.2019.09.005_bib17","first-page":"8691495","article-title":"Sleep quality and levodopa intestinal gel infusion in Parkinson's disease: a pilot study","volume":"2018","author":"De Fabregues","year":"2018","journal-title":"Parkinsons Dis"},{"issue":"2","key":"10.1016\/j.cger.2019.09.005_bib18","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/mds.27602","article-title":"Update on treatments for nonmotor symptoms of Parkinson's disease-an evidence-based medicine review","volume":"34","author":"Seppi","year":"2019","journal-title":"Mov Disord"},{"key":"10.1016\/j.cger.2019.09.005_bib19","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.sleep.2018.01.001","article-title":"The effect of light exposure on insomnia and nocturnal movement in Parkinson's disease: an open label, retrospective, longitudinal study","volume":"44","author":"Martino","year":"2018","journal-title":"Sleep Med"},{"issue":"6","key":"10.1016\/j.cger.2019.09.005_bib20","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1001\/archneur.59.6.986","article-title":"Contributions of dopaminergic drugs and disease severity to daytime sleepiness in Parkinson disease","volume":"59","author":"O'Suilleabhain","year":"2002","journal-title":"Arch Neurol"},{"issue":"11","key":"10.1016\/j.cger.2019.09.005_bib21","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1136\/jnnp-2017-316136","article-title":"Impact of sleep-related symptoms on clinical motor subtypes and disability in Parkinson's disease: a multicentre cross-sectional study","volume":"88","author":"Suzuki","year":"2017","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"8","key":"10.1016\/j.cger.2019.09.005_bib22","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1136\/jnnp-2016-315023","article-title":"Longitudinal assessment of excessive daytime sleepiness in early Parkinson's disease","volume":"88","author":"Amara","year":"2017","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"3","key":"10.1016\/j.cger.2019.09.005_bib23","first-page":"636","article-title":"Daytime sleepiness may be an independent symptom unrelated to sleep quality in Parkinson's disease","volume":"266","author":"Liguori","year":"2019","journal-title":"J\u00a0Neurol"},{"issue":"2","key":"10.1016\/j.cger.2019.09.005_bib24","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0197-4580(02)00065-9","article-title":"Staging of brain pathology related to sporadic Parkinson's disease","volume":"24","author":"Braak","year":"2003","journal-title":"Neurobiol Aging"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib25","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/mdc3.12063","article-title":"Sleep attacks in patients with Parkinson's disease on dopaminergic medications: a systematic review","volume":"1","author":"Yeung","year":"2014","journal-title":"Movement Disord Clin Pract"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib26","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1046\/j.1365-2869.2000.00177.x","article-title":"Sensitivity and specificity of the multiple sleep latency test (MSLT), the maintenance of wakefulness test and the epworth sleepiness scale: failure of the MSLT as a gold standard","volume":"9","author":"Johns","year":"2000","journal-title":"J\u00a0Sleep Res"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib27","doi-asserted-by":"crossref","first-page":"530","DOI":"10.3988\/jcn.2018.14.4.530","article-title":"Clinical predictors of excessive daytime sleepiness in patients with Parkinson's disease","volume":"14","author":"Junho","year":"2018","journal-title":"J\u00a0Clin Neurol (Seoul, Korea)"},{"key":"10.1016\/j.cger.2019.09.005_bib28","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3389\/fneur.2019.00121","article-title":"Clinical features and correlates of excessive daytime sleepiness in Parkinson's disease","volume":"10","author":"Xiang","year":"2019","journal-title":"Front Neurol"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib29","doi-asserted-by":"crossref","first-page":"177","DOI":"10.5665\/sleep.3332","article-title":"Continuous positive airway pressure improves sleep and daytime sleepiness in patients with Parkinson disease and sleep apnea","volume":"37","author":"Neikrug","year":"2014","journal-title":"Sleep"},{"issue":"5","key":"10.1016\/j.cger.2019.09.005_bib30","doi-asserted-by":"crossref","first-page":"819","DOI":"10.5664\/jcsm.7114","article-title":"Change in cognition and other non-motor symptoms with obstructive sleep apnea treatment in Parkinson disease","volume":"14","author":"Kaminska","year":"2018","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib31","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1001\/jamaneurol.2016.5192","article-title":"Timed light therapy for sleep and daytime sleepiness associated with Parkinson disease: a randomized clinical trial","volume":"74","author":"Videnovic","year":"2017","journal-title":"JAMA Neurol"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib32","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1001\/jamaneurol.2017.3171","article-title":"Sodium oxybate for excessive daytime sleepiness and sleep disturbance in Parkinson disease: a randomized clinical trial","volume":"75","author":"Buchele","year":"2018","journal-title":"JAMA Neurol"},{"issue":"6","key":"10.1016\/j.cger.2019.09.005_bib33","doi-asserted-by":"crossref","first-page":"e100828","DOI":"10.1371\/journal.pone.0100828","article-title":"Observations on sleep-disordered breathing in idiopathic Parkinson's disease","volume":"9","author":"Valko","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib34","first-page":"805","article-title":"Observational study of the relation between Parkinson's disease and sleep apnea","volume":"5","author":"Beland","year":"2015","journal-title":"J\u00a0Parkinsons Dis"},{"key":"10.1016\/j.cger.2019.09.005_bib35","first-page":"849472","article-title":"The interaction between obstructive sleep apnea and Parkinson's disease: possible mechanisms and Implications for cognitive function","volume":"2015","author":"Kaminska","year":"2015","journal-title":"Parkinsons Dis"},{"issue":"2","key":"10.1016\/j.cger.2019.09.005_bib36","doi-asserted-by":"crossref","first-page":"183","DOI":"10.5664\/jcsm.7612","article-title":"Effect of three hypopnea scoring criteria on OSA prevalence and associated comorbidities in the general population","volume":"15","author":"Hirotsu","year":"2019","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.cger.2019.09.005_bib37","doi-asserted-by":"crossref","first-page":"15015","DOI":"10.1038\/nrdp.2015.15","article-title":"Obstructive sleep apnoea syndrome","volume":"1","author":"Levy","year":"2015","journal-title":"Nat Rev Dis Primers"},{"issue":"13","key":"10.1016\/j.cger.2019.09.005_bib38","doi-asserted-by":"crossref","first-page":"2246","DOI":"10.1002\/mds.23231","article-title":"No increased risk of obstructive sleep apnea in Parkinson's disease","volume":"25","author":"Trotti","year":"2010","journal-title":"Mov Disord"},{"issue":"2","key":"10.1016\/j.cger.2019.09.005_bib39","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s11325-018-1729-0","article-title":"Laryngopharyngeal motor dysfunction and obstructive sleep apnea in Parkinson's disease","volume":"23","author":"Bahia","year":"2019","journal-title":"Sleep Breath"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib40","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s11325-015-1208-9","article-title":"Obstructive sleep apnea in Parkinson's disease patients: effect of Sinemet CR taken at bedtime","volume":"20","author":"Gros","year":"2016","journal-title":"Sleep Breath"},{"issue":"50","key":"10.1016\/j.cger.2019.09.005_bib41","doi-asserted-by":"crossref","first-page":"e5559","DOI":"10.1097\/MD.0000000000005559","article-title":"Levodopa reverse stridor and prevent subsequent endotracheal intubation in Parkinson disease patients with bilateral vocal cord palsy: a case report","volume":"95","author":"Tsai","year":"2016","journal-title":"Medicine (Baltimore)"},{"issue":"3","key":"10.1016\/j.cger.2019.09.005_bib42","doi-asserted-by":"crossref","first-page":"479","DOI":"10.5664\/jcsm.6506","article-title":"Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American academy of sleep medicine clinical practice guideline","volume":"13","author":"Kapur","year":"2017","journal-title":"J\u00a0Clin Sleep Med"},{"key":"10.1016\/j.cger.2019.09.005_bib43","first-page":"258418","article-title":"Diagnosis of obstructive sleep apnea in Parkinson's disease patients: is unattended portable monitoring a suitable tool?","volume":"2015","author":"Gros","year":"2015","journal-title":"Parkinsons Dis"},{"issue":"12","key":"10.1016\/j.cger.2019.09.005_bib44","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1212\/WNL.0000000000003738","article-title":"Reduced cognitive function in patients with Parkinson disease and obstructive sleep apnea","volume":"88","author":"Mery","year":"2017","journal-title":"Neurology"},{"issue":"8","key":"10.1016\/j.cger.2019.09.005_bib45","doi-asserted-by":"crossref","first-page":"899","DOI":"10.4103\/0366-6999.229888","article-title":"Effect of rapid eye movement sleep behavior disorder on obstructive sleep apnea severity and cognition of Parkinson's disease patients","volume":"131","author":"Huang","year":"2018","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.cger.2019.09.005_bib46","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.sleep.2017.11.1146","article-title":"Prevalence of restless legs syndrome in Parkinson's disease: a systematic review and meta-analysis of observational studies","volume":"43","author":"Yang","year":"2018","journal-title":"Sleep Med"},{"issue":"2","key":"10.1016\/j.cger.2019.09.005_bib47","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsw065","article-title":"Association of restless legs syndrome with incident Parkinson's disease","volume":"40","author":"Szatmari","year":"2017","journal-title":"Sleep"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib48","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1002\/mds.22410","article-title":"Factors contributing to the development of restless legs syndrome in patients with Parkinson disease","volume":"24","author":"Lee","year":"2009","journal-title":"Mov Disord"},{"issue":"1\u20132","key":"10.1016\/j.cger.2019.09.005_bib49","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.jns.2011.08.012","article-title":"A\u00a0study of the prevalence of restless legs syndrome in previously untreated Parkinson's disease patients: absence of co-morbid association","volume":"310","author":"Angelini","year":"2011","journal-title":"J\u00a0Neurol Sci"},{"issue":"2","key":"10.1016\/j.cger.2019.09.005_bib50","doi-asserted-by":"crossref","first-page":"405","DOI":"10.5665\/sleep.5452","article-title":"A\u00a0four-year longitudinal study on restless legs syndrome in Parkinson disease","volume":"39","author":"Moccia","year":"2016","journal-title":"Sleep"},{"issue":"4","key":"10.1016\/j.cger.2019.09.005_bib51","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/ane.12307","article-title":"Restless legs syndrome in patients with Parkinson's disease: a comparative study on prevalence, clinical characteristics, quality of life and nutritional status","volume":"131","author":"Fereshtehnejad","year":"2015","journal-title":"Acta Neurol Scand"},{"key":"10.1016\/j.cger.2019.09.005_bib52","doi-asserted-by":"crossref","first-page":"551","DOI":"10.3389\/fneur.2018.00551","article-title":"Restless legs syndrome and Parkinson disease: a causal relationship between the two disorders?","volume":"9","author":"Ferini-Strambi","year":"2018","journal-title":"Front Neurol"},{"issue":"20","key":"10.1016\/j.cger.2019.09.005_bib53","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1212\/WNL.0000000000007500","article-title":"Association between restless legs syndrome and other movement disorders","volume":"92","author":"Alonso-Navarro","year":"2019","journal-title":"Neurology"},{"issue":"6","key":"10.1016\/j.cger.2019.09.005_bib54","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s11910-018-0838-2","article-title":"Disturbances of sleep and alertness in Parkinson's disease","volume":"18","author":"Videnovic","year":"2018","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.cger.2019.09.005_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.sleep.2016.01.017","article-title":"Guidelines for the first-line treatment of restless legs syndrome\/Willis-Ekbom disease, prevention and treatment of dopaminergic augmentation: a combined task force of the IRLSSG, EURLSSG, and the RLS-foundation","volume":"21","author":"Garcia-Borreguero","year":"2016","journal-title":"Sleep Med"},{"issue":"5","key":"10.1016\/j.cger.2019.09.005_bib56","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/mds.26929","article-title":"Restless legs syndrome and periodic leg movements in patients with movement disorders: specific considerations","volume":"32","author":"Hogl","year":"2017","journal-title":"Mov Disord"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib57","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.sleep.2011.03.021","article-title":"Efficacy and safety of pramipexole in Chinese patients with restless legs syndrome: results from a multi-center, randomized, double-blind, placebo-controlled trial","volume":"13","author":"Ma","year":"2012","journal-title":"Sleep Med"},{"issue":"9","key":"10.1016\/j.cger.2019.09.005_bib58","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/j.sleep.2010.02.014","article-title":"Rotigotine transdermal patch in moderate to severe idiopathic restless legs syndrome: a randomized, placebo-controlled polysomnographic study","volume":"11","author":"Oertel","year":"2010","journal-title":"Sleep Med"},{"issue":"12","key":"10.1016\/j.cger.2019.09.005_bib59","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1002\/mds.20257","article-title":"Ropinirole is effective in the treatment of restless legs syndrome. TREAT RLS 2: a 12-week, double-blind, randomized, parallel-group, placebo-controlled study","volume":"19","author":"Walters","year":"2004","journal-title":"Mov Disord"},{"issue":"6","key":"10.1016\/j.cger.2019.09.005_bib60","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/WNF.0b013e3181b3ab16","article-title":"Gabapentin enacarbil in restless legs syndrome: a phase 2b, 2-week, randomized, double-blind, placebo-controlled trial","volume":"32","author":"Walters","year":"2009","journal-title":"Clin Neuropharmacol"},{"issue":"7","key":"10.1016\/j.cger.2019.09.005_bib61","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1056\/NEJMoa1303646","article-title":"Comparison of pregabalin with pramipexole for restless legs syndrome","volume":"370","author":"Allen","year":"2014","journal-title":"N\u00a0Engl J Med"},{"issue":"24","key":"10.1016\/j.cger.2019.09.005_bib62","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1212\/WNL.0000000000003388","article-title":"Practice guideline summary: treatment of restless legs syndrome in adults: report of the guideline development, dissemination, and implementation subcommittee of the American Academy of Neurology","volume":"87","author":"Winkelman","year":"2016","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.cger.2019.09.005_bib63","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.parkreldis.2010.11.017","article-title":"Effects of STN DBS for Parkinson's disease on restless legs syndrome and other sleep-related measures","volume":"17","author":"Chahine","year":"2011","journal-title":"Parkinsonism Relat Disord"},{"issue":"11","key":"10.1016\/j.cger.2019.09.005_bib64","doi-asserted-by":"crossref","first-page":"e1013","DOI":"10.1212\/WNL.0000000000006162","article-title":"Deep brain stimulation improves restless legs syndrome in patients with Parkinson disease","volume":"91","author":"Klepitskaya","year":"2018","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib65","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/00002826-200001000-00006","article-title":"Diurnal motor variations to repeated doses of levodopa in Parkinson's disease","volume":"23","author":"Bonuccelli","year":"2000","journal-title":"Clin Neuropharmacol"},{"issue":"2","key":"10.1016\/j.cger.2019.09.005_bib66","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.autneu.2011.07.010","article-title":"Circadian rhythm of rest activity and autonomic nervous system activity at different stages in Parkinson's disease","volume":"165","author":"Niwa","year":"2011","journal-title":"Auton Neurosci"},{"issue":"3","key":"10.1016\/j.cger.2019.09.005_bib67","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.sleep.2013.10.016","article-title":"Disturbances in melatonin secretion and circadian sleep-wake regulation in Parkinson disease","volume":"15","author":"Bolitho","year":"2014","journal-title":"Sleep Med"},{"issue":"11","key":"10.1016\/j.cger.2019.09.005_bib68","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1212\/WNL.0000000000007078","article-title":"Enlightened PD: a novel treatment for Parkinson disease?","volume":"92","author":"Videnovic","year":"2019","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.cger.2019.09.005_bib69","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1080\/07420520701420717","article-title":"Primary and secondary features of Parkinson's disease improve with strategic exposure to bright light: a case series study","volume":"24","author":"Willis","year":"2007","journal-title":"Chronobiol Int"},{"key":"10.1016\/j.cger.2019.09.005_bib70","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.pneurobio.2019.01.002","article-title":"Chronotherapies for Parkinson's disease","volume":"174","author":"Fifel","year":"2019","journal-title":"Prog Neurobiol"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib71","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/s12883-017-0795-4","article-title":"Meta-analysis on the prevalence of REM sleep behavior disorder symptoms in Parkinson's disease","volume":"17","author":"Zhang","year":"2017","journal-title":"BMC Neurol"},{"issue":"14","key":"10.1016\/j.cger.2019.09.005_bib72","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1212\/WNL.0b013e3182a6cbd5","article-title":"Nonmotor and diagnostic findings in subjects with de novo Parkinson disease of the DeNoPa cohort","volume":"81","author":"Mollenhauer","year":"2013","journal-title":"Neurology"},{"issue":"3","key":"10.1016\/j.cger.2019.09.005_bib73","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1093\/brain\/awz030","article-title":"Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study","volume":"142","author":"Postuma","year":"2019","journal-title":"Brain"},{"issue":"11","key":"10.1016\/j.cger.2019.09.005_bib74","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/nrneurol.2016.152","article-title":"Advances in markers of prodromal Parkinson disease","volume":"12","author":"Postuma","year":"2016","journal-title":"Nat Rev Neurol"},{"issue":"6","key":"10.1016\/j.cger.2019.09.005_bib75","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1212\/WNL.0b013e3181ec7fac","article-title":"REM sleep behavior disorder preceding other aspects of synucleinopathies by up to half a century","volume":"75","author":"Claassen","year":"2010","journal-title":"Neurology"},{"issue":"Pt 11","key":"10.1016\/j.cger.2019.09.005_bib76","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1093\/brain\/awm056","article-title":"Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease","volume":"130","author":"Boeve","year":"2007","journal-title":"Brain"},{"issue":"16","key":"10.1016\/j.cger.2019.09.005_bib77","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1002\/mds.21740","article-title":"The REM sleep behavior disorder screening questionnaire--a new diagnostic instrument","volume":"22","author":"Stiasny-Kolster","year":"2007","journal-title":"Mov Disord"},{"issue":"6","key":"10.1016\/j.cger.2019.09.005_bib78","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s10072-017-2886-9","article-title":"Diagnostic accuracy of REM sleep behaviour disorder screening questionnaire: a meta-analysis","volume":"38","author":"Li","year":"2017","journal-title":"Neurol Sci"},{"key":"10.1016\/j.cger.2019.09.005_bib79","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.jocn.2017.09.019","article-title":"REM sleep behavior disorder portends poor prognosis in Parkinson's disease: a systematic review","volume":"47","author":"Kim","year":"2018","journal-title":"J\u00a0Clin Neurosci"},{"issue":"11","key":"10.1016\/j.cger.2019.09.005_bib80","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/j.mayocp.2017.09.007","article-title":"REM sleep behavior disorder: diagnosis, clinical implications, and future directions","volume":"92","author":"St Louis","year":"2017","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.cger.2019.09.005_bib81","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.smrv.2016.11.002","article-title":"Idiopathic REM sleep behavior disorder and neurodegenerative risk: to tell or not to tell to the patient? How to minimize the risk?","volume":"36","author":"Arnaldi","year":"2017","journal-title":"Sleep Med Rev"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib82","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/s41572-018-0016-5","article-title":"REM sleep behaviour disorder","volume":"4","author":"Dauvilliers","year":"2018","journal-title":"Nat Rev Dis Primers"},{"issue":"5","key":"10.1016\/j.cger.2019.09.005_bib83","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1212\/01.wnl.0000233926.47469.73","article-title":"Update on the pharmacology of REM sleep behavior disorder","volume":"67","author":"Gagnon","year":"2006","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.cger.2019.09.005_bib84","doi-asserted-by":"crossref","first-page":"85","DOI":"10.5664\/jcsm.27717","article-title":"Best practice guide for the treatment of REM sleep behavior disorder (RBD)","volume":"6","author":"Aurora","year":"2010","journal-title":"J\u00a0Clin Sleep Med"},{"issue":"3","key":"10.1016\/j.cger.2019.09.005_bib85","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.sleep.2012.09.018","article-title":"Treatment outcomes in REM sleep behavior disorder","volume":"14","author":"McCarter","year":"2013","journal-title":"Sleep Med"}],"container-title":["Clinics in Geriatric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749069019300801?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749069019300801?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:55:23Z","timestamp":1760061323000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749069019300801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":85,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S0749069019300801"],"URL":"https:\/\/doi.org\/10.1016\/j.cger.2019.09.005","relation":{},"ISSN":["0749-0690"],"issn-type":[{"value":"0749-0690","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Overview of Sleep and Circadian Rhythm Disorders in Parkinson Disease","name":"articletitle","label":"Article Title"},{"value":"Clinics in Geriatric Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cger.2019.09.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}