{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T03:55:02Z","timestamp":1774410902519,"version":"3.50.1"},"reference-count":77,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","geriatric.theclinics.com","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinics in Geriatric Medicine"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.cger.2021.01.002","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T16:14:39Z","timestamp":1616516079000},"page":"279-288","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Small Fiber Neuropathy in the Elderly"],"prefix":"10.1016","volume":"37","author":[{"given":"Lan","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.cger.2021.01.002_bib1","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3949\/ccjm.76a.08070","article-title":"Small fiber neuropathy: a burning problem","volume":"76","author":"Tavee","year":"2009","journal-title":"Cleve Clin J Med"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib2","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/ene.13508","article-title":"Associated conditions in small fiber neuropathy - a large cohort study and review of the literature","volume":"25","author":"de Greef","year":"2018","journal-title":"Eur J Neurol"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib3","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/mus.22255","article-title":"Characterization of non-length-dependent small-fiber sensory neuropathy","volume":"45","author":"Khan","year":"2012","journal-title":"Muscle Nerve"},{"issue":"5","key":"10.1016\/j.cger.2021.01.002_bib4","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1097\/WCO.0000000000000472","article-title":"Small fibre neuropathy","volume":"30","author":"Cazzato","year":"2017","journal-title":"Curr Opin Neurol"},{"issue":"5","key":"10.1016\/j.cger.2021.01.002_bib5","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1002\/mus.25082","article-title":"Small fiber neuropathy: getting bigger!","volume":"53","author":"Chan","year":"2016","journal-title":"Muscle Nerve"},{"issue":"5","key":"10.1016\/j.cger.2021.01.002_bib6","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1055\/s-0039-1688977","article-title":"Small fiber neuropathy","volume":"39","author":"Zhou","year":"2019","journal-title":"Semin Neurol"},{"issue":"47","key":"10.1016\/j.cger.2021.01.002_bib7","doi-asserted-by":"crossref","first-page":"19444","DOI":"10.1073\/pnas.1216080109","article-title":"Gain-of-function Nav1.8 mutations in painful neuropathy","volume":"109","author":"Faber","year":"2012","journal-title":"Proc Natl Acad Sci U\u00a0S\u00a0A"},{"key":"10.1016\/j.cger.2021.01.002_bib8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.neulet.2014.12.056","article-title":"Painful peripheral neuropathy and sodium channel mutations","volume":"596","author":"Hoeijmakers","year":"2015","journal-title":"Neurosci Lett"},{"issue":"Pt 6","key":"10.1016\/j.cger.2021.01.002_bib9","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1093\/brain\/awu079","article-title":"Gain-of-function mutations in sodium channel Na(v)1.9 in painful neuropathy","volume":"137","author":"Huang","year":"2014","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib10","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1136\/jnnp-2018-319042","article-title":"Yield of peripheral sodium channels gene screening in pure small fibre neuropathy","volume":"90","author":"Eijkenboom","year":"2019","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"15","key":"10.1016\/j.cger.2021.01.002_bib11","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1212\/WNL.0b013e3182a8236e","article-title":"Incidence and prevalence of small-fiber neuropathy: a survey in The Netherlands","volume":"81","author":"Peters","year":"2013","journal-title":"Neurology"},{"issue":"8","key":"10.1016\/j.cger.2021.01.002_bib12","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1007\/s40266-015-0283-8","article-title":"Neuropathic pain due to small fiber neuropathy in aging: current management and future prospects","volume":"32","author":"Brouwer","year":"2015","journal-title":"Drugs Aging"},{"issue":"4","key":"10.1016\/j.cger.2021.01.002_bib13","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/CND.0b013e3182196e3c","article-title":"Metabolic syndrome in small fiber sensory neuropathy","volume":"12","author":"Zhou","year":"2011","journal-title":"J\u00a0Clin Neuromuscul Dis"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib14","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1002\/mus.23910","article-title":"Small fibers, large impact: quality of life in small-fiber neuropathy","volume":"49","author":"Bakkers","year":"2014","journal-title":"Muscle Nerve"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib15","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/mus.10181","article-title":"Small-fiber neuropathy","volume":"26","author":"Lacomis","year":"2002","journal-title":"Muscle Nerve"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib16","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1529-8027.2010.00252.x","article-title":"Non-length dependent small fiber neuropathy. a prospective case series","volume":"15","author":"Gemignani","year":"2010","journal-title":"J\u00a0Peripher Nerv Syst"},{"issue":"7","key":"10.1016\/j.cger.2021.01.002_bib17","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1038\/nrneurol.2014.99","article-title":"Neuropathic pruritus","volume":"10","author":"Misery","year":"2014","journal-title":"Nat Rev Neurol"},{"issue":"7","key":"10.1016\/j.cger.2021.01.002_bib18","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1111\/j.1468-1331.2010.03023.x","volume":"17","author":"Lauria","year":"2010","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.cger.2021.01.002_bib19","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1212\/01.CON.0000455874.68556.02","article-title":"Small fiber neuropathies","volume":"20","author":"Gibbons","year":"2014","journal-title":"Continuum (Minneap Minn)"},{"issue":"6","key":"10.1016\/j.cger.2021.01.002_bib20","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1212\/01.wnl.0000176034.38198.f9","article-title":"Painful small-fiber neuropathy in Sjogren syndrome","volume":"65","author":"Chai","year":"2005","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib21","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1136\/jnnp.2007.128801","article-title":"Non-length dependent small fibre neuropathy\/ganglionopathy","volume":"79","author":"Gorson","year":"2008","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"key":"10.1016\/j.cger.2021.01.002_bib22","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.rmed.2017.03.011","article-title":"Sarcoidosis-associated small fiber neuropathy in a large cohort: clinical aspects and response to IVIG and anti-TNF alpha treatment","volume":"126","author":"Tavee","year":"2017","journal-title":"Respir Med"},{"issue":"4","key":"10.1016\/j.cger.2021.01.002_bib23","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/mus.26824","article-title":"Small fiber neuropathy in Sjogren syndrome: comparison with other small fiber neuropathies","volume":"61","author":"Descamps","year":"2020","journal-title":"Muscle Nerve"},{"issue":"4","key":"10.1016\/j.cger.2021.01.002_bib24","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/mus.23971","article-title":"Sural sensory nerve action potential, epidermal nerve fiber density, and quantitative sudomotor axon reflex in the healthy elderly","volume":"49","author":"Tavee","year":"2014","journal-title":"Muscle Nerve"},{"issue":"Pt 7","key":"10.1016\/j.cger.2021.01.002_bib25","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1093\/brain\/awn093","article-title":"The diagnostic criteria for small fibre neuropathy: from symptoms to neuropathology","volume":"131","author":"Devigili","year":"2008","journal-title":"Brain"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib26","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S0022-510X(99)00063-5","article-title":"Epidermal innervation: changes with aging, topographic location, and in sensory neuropathy","volume":"164","author":"Lauria","year":"1999","journal-title":"J\u00a0Neurol Sci"},{"issue":"12","key":"10.1016\/j.cger.2021.01.002_bib27","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1001\/archneur.55.12.1513","article-title":"Epidermal nerve fiber density: normative reference range and diagnostic efficiency","volume":"55","author":"McArthur","year":"1998","journal-title":"Arch Neurol"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib28","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/mus.20889","article-title":"Diagnostic validity of epidermal nerve fiber densities in painful sensory neuropathies","volume":"37","author":"Vlckova-Moravcova","year":"2008","journal-title":"Muscle Nerve"},{"issue":"8","key":"10.1016\/j.cger.2021.01.002_bib29","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1002\/mus.1107","article-title":"Epidermal nerve fiber density in sensory ganglionopathies: clinical and neurophysiologic correlations","volume":"24","author":"Lauria","year":"2001","journal-title":"Muscle Nerve"},{"issue":"6","key":"10.1016\/j.cger.2021.01.002_bib30","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1111\/ene.13608","article-title":"The role of skin biopsy in differentiating small-fiber neuropathy from ganglionopathy","volume":"25","author":"Provitera","year":"2018","journal-title":"Eur J Neurol"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib31","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1212\/01.wnl.0000266967.38657.3a","article-title":"Small fiber degeneration in post-stroke complex regional pain syndrome I","volume":"69","author":"Chemali","year":"2007","journal-title":"Neurology"},{"issue":"4","key":"10.1016\/j.cger.2021.01.002_bib32","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/mus.25044","article-title":"Skin biopsy in assessing meralgia paresthetica","volume":"53","author":"Wongmek","year":"2016","journal-title":"Muscle Nerve"},{"issue":"5","key":"10.1016\/j.cger.2021.01.002_bib33","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1136\/jnnp.65.5.762","article-title":"Neuropathological alterations in diabetic truncal neuropathy: evaluation by skin biopsy","volume":"65","author":"Lauria","year":"1998","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib34","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.pain.2005.09.036","article-title":"Evidence of focal small-fiber axonal degeneration in complex regional pain syndrome-I (reflex sympathetic dystrophy)","volume":"120","author":"Oaklander","year":"2006","journal-title":"Pain"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib35","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1529-8027.2010.00271.x","article-title":"Intraepidermal nerve fiber density at the distal leg: a worldwide normative reference study","volume":"15","author":"Lauria","year":"2010","journal-title":"J\u00a0Peripher Nerv Syst"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/CND.0000000000000223","article-title":"Low sensitivity of skin biopsy in diagnosing small fiber neuropathy in Chinese Americans","volume":"20","author":"Jin","year":"2018","journal-title":"J\u00a0Clin Neuromuscul Dis"},{"issue":"9","key":"10.1016\/j.cger.2021.01.002_bib37","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1016\/j.pain.2013.05.047","article-title":"Value of quantitative sensory testing in neurological and pain disorders: NeuPSIG consensus","volume":"154","author":"Backonja","year":"2013","journal-title":"Pain"},{"issue":"6","key":"10.1016\/j.cger.2021.01.002_bib38","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1212\/01.WNL.0000058546.16985.11","article-title":"Quantitative sensory testing: report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology","volume":"60","author":"Shy","year":"2003","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib39","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/mus.20551","article-title":"Detection of small-fiber neuropathy by sudomotor testing","volume":"34","author":"Low","year":"2006","journal-title":"Muscle Nerve"},{"issue":"6","key":"10.1016\/j.cger.2021.01.002_bib40","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1002\/mus.23891","article-title":"Contribution of QSART to the diagnosis of small fiber neuropathy","volume":"48","author":"Thaisetthawatkul","year":"2013","journal-title":"Muscle Nerve"},{"issue":"4","key":"10.1016\/j.cger.2021.01.002_bib41","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/mus.26648","article-title":"Longitudinal follow-up of biopsy-proven small fiber neuropathy","volume":"60","author":"MacDonald","year":"2019","journal-title":"Muscle Nerve"},{"issue":"12","key":"10.1016\/j.cger.2021.01.002_bib42","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1212\/WNL.56.12.1727","article-title":"Painful alcoholic polyneuropathy with predominant small-fiber loss and normal thiamine status","volume":"56","author":"Koike","year":"2001","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib43","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1212\/01.wnl.0000169021.26172.f8","article-title":"Acute painful neuropathy in thallium poisoning","volume":"65","author":"Kuo","year":"2005","journal-title":"Neurology"},{"issue":"7","key":"10.1016\/j.cger.2021.01.002_bib44","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1111\/acer.12470","article-title":"Small-fiber degeneration in alcohol-related peripheral neuropathy","volume":"38","author":"Mellion","year":"2014","journal-title":"Alcohol Clin Exp Res"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib45","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1136\/jnnp.2007.127910","article-title":"Painful neuropathy with skin denervation after prolonged use of linezolid","volume":"79","author":"Chao","year":"2008","journal-title":"J\u00a0Neurol Neurosurg Psychiatry"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib46","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1529-8027.2008.00173.x","article-title":"Linezolid-associated small-fiber neuropathy","volume":"13","author":"Heckmann","year":"2008","journal-title":"J\u00a0Peripher Nerv Syst"},{"issue":"5","key":"10.1016\/j.cger.2021.01.002_bib47","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1177\/08830738060210051201","article-title":"Metronidazole: newly recognized cause of autonomic neuropathy","volume":"21","author":"Hobson-Webb","year":"2006","journal-title":"J\u00a0Child Neurol"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib48","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1001\/archneurol.2011.1120","article-title":"Peripheral nerve toxic effects of nitrofurantoin","volume":"69","author":"Tan","year":"2012","journal-title":"Arch Neurol"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib49","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00131402-200109000-00002","article-title":"Sensory neuropathy associated with metronidazole: report of four cases and review of the literature","volume":"3","author":"Zivkovic","year":"2001","journal-title":"J\u00a0Clin Neuromuscul Dis"},{"issue":"14","key":"10.1016\/j.cger.2021.01.002_bib50","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1212\/WNL.0000000000000846","article-title":"Oral fluoroquinolone use and risk of peripheral neuropathy: a pharmacoepidemiologic study","volume":"83","author":"Etminan","year":"2014","journal-title":"Neurology"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib51","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1007\/s10072-010-0475-2","article-title":"Somatic and autonomic small fiber neuropathy induced by bortezomib therapy: an immunofluorescence study","volume":"32","author":"Giannoccaro","year":"2011","journal-title":"Neurol Sci"},{"issue":"1\u20132","key":"10.1016\/j.cger.2021.01.002_bib52","first-page":"44","article-title":"Quantification of small fiber neuropathy in chemotherapy-treated patients","volume":"21","author":"Timmins","year":"2020","journal-title":"J\u00a0Pain"},{"issue":"5","key":"10.1016\/j.cger.2021.01.002_bib53","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.semarthrit.2013.10.007","article-title":"Non-length-dependent and length-dependent small-fiber neuropathies associated with tumor necrosis factor (TNF)-inhibitor therapy in patients with rheumatoid arthritis: expanding the spectrum of neurological disease associated with TNF-inhibitors","volume":"43","author":"Birnbaum","year":"2014","journal-title":"Semin Arthritis Rheum"},{"issue":"4","key":"10.1016\/j.cger.2021.01.002_bib54","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1002\/ana.21952","article-title":"Treatment-induced diabetic neuropathy: a reversible painful autonomic neuropathy","volume":"67","author":"Gibbons","year":"2010","journal-title":"Ann Neurol"},{"issue":"Pt 1","key":"10.1016\/j.cger.2021.01.002_bib55","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/brain\/awu307","article-title":"Treatment-induced neuropathy of diabetes: an acute, iatrogenic complication of diabetes","volume":"138","author":"Gibbons","year":"2015","journal-title":"Brain"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib56","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1212\/WNL.60.1.108","article-title":"The spectrum of neuropathy in diabetes and impaired glucose tolerance","volume":"60","author":"Sumner","year":"2003","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib57","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/ana.24972","article-title":"Cutaneous nerve biomarkers in transthyretin familial amyloid polyneuropathy","volume":"82","author":"Ebenezer","year":"2017","journal-title":"Ann Neurol"},{"issue":"10","key":"10.1016\/j.cger.2021.01.002_bib58","doi-asserted-by":"crossref","first-page":"801","DOI":"10.3949\/ccjm.85a.17124","article-title":"Office approach to small fiber neuropathy","volume":"85","author":"Tavee","year":"2018","journal-title":"Cleve Clin J Med"},{"issue":"Suppl 1","key":"10.1016\/j.cger.2021.01.002_bib59","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1097\/WCO.0000000000000289","article-title":"First European consensus for diagnosis, management, and treatment of transthyretin familial amyloid polyneuropathy","volume":"29","author":"Adams","year":"2016","journal-title":"Curr Opin Neurol"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib60","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1001\/jama.287.3.356","article-title":"Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey","volume":"287","author":"Ford","year":"2002","journal-title":"JAMA"},{"issue":"1\u20132","key":"10.1016\/j.cger.2021.01.002_bib61","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jns.2008.06.005","article-title":"Idiopathic neuropathy patients are at high risk for metabolic syndrome","volume":"273","author":"Smith","year":"2008","journal-title":"J\u00a0Neurol Sci"},{"issue":"4","key":"10.1016\/j.cger.2021.01.002_bib62","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1056\/NEJMoa032782","article-title":"Vascular risk factors and diabetic neuropathy","volume":"352","author":"Tesfaye","year":"2005","journal-title":"N\u00a0Engl J Med"},{"issue":"6","key":"10.1016\/j.cger.2021.01.002_bib63","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1007\/s00125-017-4253-z","article-title":"Effects of a long-term lifestyle modification programme on peripheral neuropathy in overweight or obese adults with type 2 diabetes: the Look AHEAD study","volume":"60","author":"Look","year":"2017","journal-title":"Diabetologia"},{"issue":"6","key":"10.1016\/j.cger.2021.01.002_bib64","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.2337\/dc06-0224","article-title":"Lifestyle intervention for pre-diabetic neuropathy","volume":"29","author":"Smith","year":"2006","journal-title":"Diabetes Care"},{"issue":"10","key":"10.1016\/j.cger.2021.01.002_bib65","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1001\/archneur.62.10.1574","article-title":"Small-fiber neuropathy\/neuronopathy associated with celiac disease: skin biopsy findings","volume":"62","author":"Brannagan","year":"2005","journal-title":"Arch Neurol"},{"issue":"1","key":"10.1016\/j.cger.2021.01.002_bib66","first-page":"73","article-title":"Improvement of small fiber neuropathy in a sarcoidosis patient after treatment with infliximab","volume":"23","author":"Hoitsma","year":"2006","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib67","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.cger.2008.03.011","article-title":"Diabetic neuropathy in older adults","volume":"24","author":"Vinik","year":"2008","journal-title":"Clin Geriatr Med"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib68","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1080\/15360280903098572","article-title":"Guidelines for the diagnosis and management of neuropathic pain: consensus of a group of Latin American experts","volume":"23","author":"Acevedo","year":"2009","journal-title":"J\u00a0Pain Palliat Care Pharmacother"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib69","first-page":"295","article-title":"Guidelines for the pharmacological treatment of peripheral neuropathic pain: expert panel recommendations for the middle East region","volume":"38","author":"Bohlega","year":"2010","journal-title":"J\u00a0Int Med Res"},{"issue":"20","key":"10.1016\/j.cger.2021.01.002_bib70","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1212\/WNL.0b013e3182166ebe","article-title":"Evidence-based guideline: treatment of painful diabetic neuropathy: report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation","volume":"76","author":"Bril","year":"2011","journal-title":"Neurology"},{"issue":"3 Suppl","key":"10.1016\/j.cger.2021.01.002_bib71","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.4065\/mcp.2009.0649","article-title":"Recommendations for the pharmacological management of neuropathic pain: an overview and literature update","volume":"85","author":"Dworkin","year":"2010","journal-title":"Mayo Clin Proc"},{"issue":"3","key":"10.1016\/j.cger.2021.01.002_bib72","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s11916-011-0181-7","article-title":"Diagnosis and treatment of pain in small-fiber neuropathy","volume":"15","author":"Hovaguimian","year":"2011","journal-title":"Curr Pain Headache Rep"},{"issue":"6","key":"10.1016\/j.cger.2021.01.002_bib73","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1155\/2014\/754693","article-title":"Pharmacological management of chronic neuropathic pain: revised consensus statement from the Canadian Pain Society","volume":"19","author":"Moulin","year":"2014","journal-title":"Pain Res Manag"},{"issue":"9697","key":"10.1016\/j.cger.2021.01.002_bib74","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1016\/S0140-6736(09)61081-3","article-title":"Nortriptyline and gabapentin, alone and in combination for neuropathic pain: a double-blind, randomised controlled crossover trial","volume":"374","author":"Gilron","year":"2009","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.cger.2021.01.002_bib75","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1097\/j.pain.0000000000000266","article-title":"Pain relief with lidocaine 5% patch in localized peripheral neuropathic pain in relation to pain phenotype: a randomised, double-blind, and placebo-controlled, phenotype panel study","volume":"156","author":"Demant","year":"2015","journal-title":"Pain"},{"issue":"2","key":"10.1016\/j.cger.2021.01.002_bib76","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S1474-4422(14)70251-0","article-title":"Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis","volume":"14","author":"Finnerup","year":"2015","journal-title":"Lancet Neurol"},{"issue":"7","key":"10.1016\/j.cger.2021.01.002_bib77","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1001\/jamaneurol.2017.0486","article-title":"Association of long-term opioid therapy with functional status, adverse outcomes, and mortality among patients with polyneuropathy","volume":"74","author":"Hoffman","year":"2017","journal-title":"JAMA Neurol"}],"container-title":["Clinics in Geriatric Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749069021000021?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0749069021000021?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:56:13Z","timestamp":1760061373000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0749069021000021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":77,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,5]]}},"alternative-id":["S0749069021000021"],"URL":"https:\/\/doi.org\/10.1016\/j.cger.2021.01.002","relation":{},"ISSN":["0749-0690"],"issn-type":[{"value":"0749-0690","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Small Fiber Neuropathy in the Elderly","name":"articletitle","label":"Article Title"},{"value":"Clinics in Geriatric Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cger.2021.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}