{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T03:47:00Z","timestamp":1768448820102,"version":"3.49.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1016\/j.cgh.2007.02.020","type":"journal-article","created":{"date-parts":[[2007,6,20]],"date-time":"2007-06-20T07:19:18Z","timestamp":1182323958000},"page":"761-764","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Risk of Lymphoma in Primary Biliary Cirrhosis"],"prefix":"10.1016","volume":"5","author":[{"given":"Chakri","family":"Panjala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jayant A.","family":"Talwalkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith D.","family":"Lindor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2007.02.020_bib1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0140-6736(03)13808-1","article-title":"Primary biliary cirrhosis","volume":"362","author":"Talwalkar","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.cgh.2007.02.020_bib2","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0168-8278(00)80232-9","article-title":"Ursodeoxycholic acid for primary biliary cirrhosis: lessons from the past-issues for the future","volume":"32","author":"Poupon","year":"2000","journal-title":"J Hepatol"},{"key":"10.1016\/j.cgh.2007.02.020_bib3","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1053\/gast.2002.31880","article-title":"Primary biliary cirrhosis: incidence and predictive factors of cirrhosis development in ursodiol-treated patients","volume":"122","author":"Corpechot","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2007.02.020_bib4","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/hep.1840100405","article-title":"A pilot, double-blind controlled 1-year trial of prednisolone treatment in primary biliary cirrhosis: hepatic improvement but greater bone loss","volume":"10","author":"Mitchison","year":"1989","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2007.02.020_bib5","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/0168-8278(92)90065-W","article-title":"A controlled trial of prednisolone treatment in primary biliary cirrhosis: three-year results","volume":"15","author":"Mitchison","year":"1992","journal-title":"J Hepatol"},{"key":"10.1016\/j.cgh.2007.02.020_bib6","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/0016-5085(80)90784-2","article-title":"Azathioprine in primary biliary cirrhosis: a preliminary report of an international trial","volume":"78","author":"Crowe","year":"1980","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2007.02.020_bib7","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/0016-5085(85)90213-6","article-title":"Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis: final results of an international trial","volume":"89","author":"Christensen","year":"1985","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2007.02.020_bib8","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/0016-5085(91)90085-Y","article-title":"Treatment of primary biliary cirrhosis with low-dose weekly methotrexate","volume":"101","author":"Kaplan","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2007.02.020_bib9","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1053\/gast.1999.0029900400","article-title":"Low-dose of methotrexate is ineffective in primary biliary cirrhosis: long-term results of a placebo-controlled trial","volume":"117","author":"Hendrickse","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2007.02.020_bib10","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1056\/NEJM199005173222003","article-title":"A controlled trial of cyclosporine in the treatment of primary biliary cirrhosis","volume":"322","author":"Wiesner","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cgh.2007.02.020_bib11","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/0016-5085(93)90422-9","article-title":"Cyclosporin A treatment in primary biliary cirrhosis: results of a long-term placebo controlled trial","volume":"104","author":"Lombard","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2007.02.020_bib12","doi-asserted-by":"crossref","first-page":"2462","DOI":"10.1056\/NEJMoa050516","article-title":"Infliximab for induction and maintenance therapy for ulcerative colitis","volume":"353","author":"Rutgeerts","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cgh.2007.02.020_bib13","doi-asserted-by":"crossref","first-page":"2167","DOI":"10.1056\/NEJMra032906","article-title":"New drugs for rheumatoid arthritis","volume":"350","author":"Olsen","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.cgh.2007.02.020_bib14","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1136\/gut.2003.020552","article-title":"Balancing the risks and benefits of infliximab in the treatment of inflammatory bowel disease","volume":"53","author":"Sandborn","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2007.02.020_bib15","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF00432479","article-title":"Staging of chronic nonsuppurative destructive cholangitis (syndrome of primary biliary cirrhosis)","volume":"379","author":"Ludwig","year":"1978","journal-title":"Virchows Arch"},{"key":"10.1016\/j.cgh.2007.02.020_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hep.1840100102","article-title":"Prognosis in primary biliary cirrhosis: model for decision making","volume":"10","author":"Dickson","year":"1989","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2007.02.020_bib17","first-page":"404","article-title":"Primary hepatic low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) associated with primary biliary cirrhosis","volume":"11","author":"Prabhu","year":"1998","journal-title":"Mod Pathol"},{"key":"10.1016\/j.cgh.2007.02.020_bib18","doi-asserted-by":"crossref","first-page":"604","DOI":"10.5858\/2000-124-0604-PHMZBC","article-title":"Primary hepatic marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type in a patient with primary biliary cirrhosis","volume":"124","author":"Ye","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.cgh.2007.02.020_bib19","first-page":"9116","article-title":"[B cell malignancy associated with Sjogren syndrome and primary biliary cirrhosis: a case report and review]","volume":"28","author":"Ijichi","year":"1987","journal-title":"Rinsho Ketsueki"},{"key":"10.1016\/j.cgh.2007.02.020_bib20","first-page":"262","article-title":"Association of splenic lymphoma with villous lymphocytes and primary biliary cirrhosis in a man","volume":"41","author":"de Figueiredo","year":"1996","journal-title":"Sangre"},{"key":"10.1016\/j.cgh.2007.02.020_bib21","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1365-2559.1993.tb00102.x","article-title":"Primary liver lymphoma associated with primary biliary cirrhosis","volume":"22","author":"Goldin","year":"1993","journal-title":"Histopathology"},{"key":"10.1016\/j.cgh.2007.02.020_bib22","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1111\/j.1572-0241.2000.t01-1-01811.x","article-title":"Primary hepatic lymphoma and primary biliary cirrhosis","volume":"95","author":"Lizarralde","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2007.02.020_bib23","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/0002-9343(84)90861-1","article-title":"Malignancy in primary biliary cirrhosis: high incidence of breast cancer in affected women","volume":"76","author":"Wolke","year":"1984","journal-title":"Am J Med"},{"key":"10.1016\/j.cgh.2007.02.020_bib24","first-page":"215","article-title":"Case report of multiple myeloma and hypothyroidism in primary biliary cirrhosis","volume":"49","author":"Rodriguez-Leal","year":"1997","journal-title":"Revista de Investigacion Clinica"},{"key":"10.1016\/j.cgh.2007.02.020_bib25","first-page":"404","article-title":"Primary hepatic low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) associated with primary biliary cirrhosis","volume":"11","author":"Prabhu","year":"1998","journal-title":"Mod Pathol"},{"key":"10.1016\/j.cgh.2007.02.020_bib26","doi-asserted-by":"crossref","first-page":"604","DOI":"10.5858\/2000-124-0604-PHMZBC","article-title":"Primary hepatic marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type in a patient with primary biliary cirrhosis","volume":"124","author":"Ye","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.cgh.2007.02.020_bib27","first-page":"911","article-title":"[B cell malignancy associated with Sjogren syndrome and primary biliary cirrhosis: a case report and review]","volume":"28","author":"Ijichi","year":"1987","journal-title":"Rinsho Ketsueki"},{"key":"10.1016\/j.cgh.2007.02.020_bib28","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1111\/j.1365-2559.1993.tb00102.x","article-title":"Primary liver lymphoma associated with primary biliary cirrhosis","volume":"22","author":"Goldin","year":"1993","journal-title":"Histopathology"},{"key":"10.1016\/j.cgh.2007.02.020_bib29","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1111\/j.1572-0241.2000.t01-1-01811.x","article-title":"Primary hepatic lymphoma and primary biliary cirrhosis","volume":"95","author":"Lizarralde","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2007.02.020_bib30","doi-asserted-by":"crossref","first-page":"367","DOI":"10.3109\/00365529509093292","article-title":"Primary biliary cirrhosis in Estonia: with special reference to incidence, prevalence, clinical features, and outcome","volume":"30","author":"Remmel","year":"1995","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.cgh.2007.02.020_bib31","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1093\/ije\/26.4.830","article-title":"Incidence and prevalence of primary biliary cirrhosis in the city of Newcastle upon Tyne, England","volume":"26","author":"Metcalf","year":"1997","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.cgh.2007.02.020_bib32","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1136\/gut.36.6.927","article-title":"Low prevalence of primary biliary cirrhosis in Victoria, Australia: Melbourne Liver Group","volume":"36","author":"Watson","year":"1995","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2007.02.020_bib33","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1053\/gast.2000.20197","article-title":"Epidemiology and natural history of primary biliary cirrhosis in a US community","volume":"119","author":"Kim","year":"2000","journal-title":"Gastroenterology"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356507002121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356507002121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T04:59:42Z","timestamp":1761541182000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356507002121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["S1542356507002121"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2007.02.020","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2007,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk of Lymphoma in Primary Biliary Cirrhosis","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2007.02.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2007 AGA Institute. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}