{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:42:11Z","timestamp":1790286131018,"version":"4.1.0"},"reference-count":16,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.cgh.2012.01.015","type":"journal-article","created":{"date-parts":[[2012,1,30]],"date-time":"2012-01-30T19:07:07Z","timestamp":1327950427000},"page":"932-937.e1","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":86,"title":["Levels of Alanine Aminotransferase Confound Use of Transient Elastography to Diagnose Fibrosis in Patients With Chronic Hepatitis C Virus Infection"],"prefix":"10.1016","volume":"10","author":[{"given":"Elliot B.","family":"Tapper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric B.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keyur","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Bacon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Lawitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Imad A.","family":"Nasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Challies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nezam","family":"Afdhal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2012.01.015_bib1","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1097\/MCG.0b013e3181e12c39","article-title":"Ultrasound-based hepatic elastography: origins, limitations, and applications","volume":"44","author":"Cohen","year":"2010","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.cgh.2012.01.015_bib2","doi-asserted-by":"crossref","first-page":"6154","DOI":"10.3748\/wjg.14.6154","article-title":"Liver stiffness in the hepatitis B virus carrier: a non-invasive marker of liver disease influenced by the pattern of transaminases","volume":"14","author":"Oliveri","year":"2008","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cgh.2012.01.015_bib3","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1002\/hep.22056","article-title":"Transient elastography is unreliable for detection of cirrhosis in patients with acute liver damage","volume":"47","author":"Sagir","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2012.01.015_bib4","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1053\/j.gastro.2004.11.018","article-title":"Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C","volume":"128","author":"Cast\u00e9ra","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2012.01.015_bib5","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1002\/hep.23312","article-title":"Diagnosis of fibrosis and cirrhosis using liver stiffness measurement in nonalcoholic fatty liver disease","volume":"51","author":"Wong","year":"2010","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2012.01.015_bib6","doi-asserted-by":"crossref","first-page":"G1147","DOI":"10.1152\/ajpgi.00032.2007","article-title":"Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis","volume":"293","author":"Georges","year":"2007","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.cgh.2012.01.015_bib7","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1136\/gut.2006.111302","article-title":"Reproducibility of transient elastography in the evaluation of liver fibrosis in patients with chronic liver disease","volume":"56","author":"Fraquelli","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2012.01.015_bib8","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1053\/j.gastro.2008.01.034","article-title":"Performance of transient elastography for the staging of liver fibrosis: a meta-analysis","volume":"134","author":"Friedrich-Rust","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2012.01.015_bib9","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/hep.20506","article-title":"Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C","volume":"41","author":"Ziol","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2012.01.015_bib10","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1002\/hep.22007","article-title":"Acute viral hepatitis increases liver stiffness values measured by transient elastography","volume":"47","author":"Arena","year":"2008","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2012.01.015_bib11","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1086\/597350","article-title":"Assessment of liver fibrosis by transient elastography in persons with hepatitis C virus infection or HIV-hepatitis C virus coinfection","volume":"48","author":"Kirk","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.cgh.2012.01.015_bib12","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1111\/j.1872-034X.2009.00500.x","article-title":"Liver stiffness measured by transient elastography correlates with fibrosis area in liver biopsy in patients with chronic hepatitis C","volume":"39","author":"Nitta","year":"2009","journal-title":"Hepatol Res"},{"key":"10.1016\/j.cgh.2012.01.015_bib13","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/j.1365-2893.2006.00811.x","article-title":"Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases","volume":"14","author":"Coco","year":"2007","journal-title":"J Viral Hepat"},{"key":"10.1016\/j.cgh.2012.01.015_bib14","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1365-2893.2008.01055.x","article-title":"Changes of non-invasive markers and FibroScan values during HCV treatment","volume":"16","author":"Vergniol","year":"2009","journal-title":"J Viral Hepat"},{"key":"10.1016\/j.cgh.2012.01.015_bib15","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.cgh.2008.02.038","article-title":"Assessment of fibrosis by transient elastography compared with liver biopsy and morphometry in chronic liver diseases","volume":"6","author":"Wong","year":"2008","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2012.01.015_bib16","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1016\/j.cgh.2007.07.020","article-title":"Ultrasound-based transient elastography for the detection of hepatic fibrosis: systematic review and meta-analysis","volume":"5","author":"Talwalkar","year":"2007","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356512001140?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356512001140?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:10:19Z","timestamp":1761541819000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356512001140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S1542356512001140"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2012.01.015","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Levels of Alanine Aminotransferase Confound Use of Transient Elastography to Diagnose Fibrosis in Patients With Chronic Hepatitis C Virus Infection","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2012.01.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 AGA Institute. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}