{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T11:32:34Z","timestamp":1792150354689,"version":"4.4.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.cgh.2013.02.010","type":"journal-article","created":{"date-parts":[[2013,2,13]],"date-time":"2013-02-13T08:33:31Z","timestamp":1360744411000},"page":"913-921","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":167,"title":["Cyst Features and Risk of Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Meta-Analysis"],"prefix":"10.1016","volume":"11","author":[{"given":"Neeraj","family":"Anand","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kartik","family":"Sampath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bechien U.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2013.02.010_bib1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/BF02784942","article-title":"Analysis of small cystic lesions of the pancreas","volume":"18","author":"Kimura","year":"1995","journal-title":"Int J Pancreatol"},{"key":"10.1016\/j.cgh.2013.02.010_bib2","series-title":"Histological typing of tumours of the exocrine pancreas","author":"Kl\u00f6ppel","year":"1996"},{"key":"10.1016\/j.cgh.2013.02.010_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1159\/000090023","article-title":"International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas","volume":"6","author":"Tanaka","year":"2006","journal-title":"Pancreatology"},{"key":"10.1016\/j.cgh.2013.02.010_bib4","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.pan.2012.04.004","article-title":"International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas","volume":"12","author":"Tanaka","year":"2012","journal-title":"Pancreatology"},{"key":"10.1016\/j.cgh.2013.02.010_bib5","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.amjsurg.2010.06.020","article-title":"Mural nodule in branch duct-type intraductal papillary mucinous neoplasms of the pancreas is a marker of malignant transformation and indication for surgery","volume":"202","author":"Akita","year":"2011","journal-title":"Am J Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib6","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2739\/kurumemedj.57.91","article-title":"Utility of multidetector row CT in diagnosing branch duct IPMNS of the pancreas compared with MR cholangiopancreatography and endoscopic ultrasonography","volume":"57","author":"Arikawa","year":"2011","journal-title":"Kurume Med J"},{"key":"10.1016\/j.cgh.2013.02.010_bib7","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.amjsurg.2006.11.038","article-title":"Proposed new score predicting malignancy of intraductal papillary mucinous neoplasms of the pancreas","volume":"194","author":"Fujino","year":"2007","journal-title":"Am J Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib8","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/S0046-8177(97)90053-8","article-title":"Intraductal papillary tumors and mucinous cystic tumors of the pancreas: clinicopathologic study of 38 cases","volume":"28","author":"Fukushima","year":"1997","journal-title":"Hum Pathol"},{"key":"10.1016\/j.cgh.2013.02.010_bib9","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1097\/MPA.0b013e31820a5975","article-title":"Natural history of branch duct intraductal papillary mucinous neoplasms of the pancreas: a multicenter study in Japan","volume":"40","author":"Maguchi","year":"2011","journal-title":"Pancreas"},{"key":"10.1016\/j.cgh.2013.02.010_bib10","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/00004836-200303000-00014","article-title":"Optimal management of the branch duct type intraductal papillary mucinous neoplasms of the pancreas","volume":"36","author":"Matsumoto","year":"2003","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.cgh.2013.02.010_bib11","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s00534-009-0068-8","article-title":"Single-institution validation of the international consensus guidelines for treatment of branch duct intraductal papillary mucinous neoplasms of the pancreas","volume":"16","author":"Nagai","year":"2009","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib12","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s00268-007-9281-2","article-title":"Intraductal papillary mucinous neoplasms of the pancreas: clinicopathologic characteristics and long-term follow-up after resection","volume":"32","author":"Nagai","year":"2008","journal-title":"World J Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib13","doi-asserted-by":"crossref","first-page":"3174","DOI":"10.1245\/s10434-007-9546-x","article-title":"Surgical outcome of intraductal papillary mucinous neoplasms of the pancreas","volume":"14","author":"Nakagohri","year":"2007","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cgh.2013.02.010_bib14","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1097\/SLA.0b013e3181a189a8","article-title":"Intraductal papillary mucinous neoplasms of the pancreas: differentiation of malignant and benign tumors by endoscopic ultrasound findings of mural nodules","volume":"249","author":"Ohno","year":"2009","journal-title":"Ann Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib15","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.surg.2011.07.009","article-title":"An increase in the number of predictive factors augments the likelihood of malignancy in branch duct intraductal papillary mucinous neoplasm of the pancreas","volume":"151","author":"Ohtsuka","year":"2012","journal-title":"Surgery"},{"key":"10.1016\/j.cgh.2013.02.010_bib16","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1111\/j.1440-1746.2005.03958.x","article-title":"Clinicopathological features and medical management of intraductal papillary mucinous neoplasms","volume":"21","author":"Okabayashi","year":"2006","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2013.02.010_bib17","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1097\/MPA.0b013e3181bab60e","article-title":"Cyst size indicates malignant transformation in branch duct intraductal papillary mucinous neoplasm of the pancreas without mural nodules","volume":"39","author":"Sadakari","year":"2010","journal-title":"Pancreas"},{"key":"10.1016\/j.cgh.2013.02.010_bib18","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1007\/s00261-002-0071-x","article-title":"Management of branch duct-type intraductal papillary mucinous tumor of the pancreas based on magnetic resonance imaging","volume":"28","author":"Sai","year":"2003","journal-title":"Abdom Imaging"},{"key":"10.1016\/j.cgh.2013.02.010_bib19","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1097\/01.mcg.0000225609.63975.6f","article-title":"Management of intraductal papillary-mucinous neoplasm of the pancreas: treatment strategy based on morphologic classification","volume":"40","author":"Serikawa","year":"2006","journal-title":"J Clin Gastroenterol"},{"key":"10.1016\/j.cgh.2013.02.010_bib20","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1097\/00000658-199811000-00008","article-title":"Intraductal papillary mucinous tumors of the pancreas: imaging studies and treatment strategies","volume":"228","author":"Sugiyama","year":"1998","journal-title":"Ann Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib21","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/00006676-200404000-00005","article-title":"Cystic neoplasm of the pancreas: a Japanese multiinstitutional study of intraductal papillary mucinous tumor and mucinous cystic tumor","volume":"28","author":"Suzuki","year":"2004","journal-title":"Pancreas"},{"key":"10.1016\/j.cgh.2013.02.010_bib22","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/RCT.0b013e3180676d97","article-title":"Differential diagnosis of benign or malignant intraductal papillary mucinous neoplasm of the pancreas by multidetector row helical computed tomography: evaluation of predictive factors by logistic regression analysis","volume":"32","author":"Takeshita","year":"2008","journal-title":"J Comput Assist Tomogr"},{"key":"10.1016\/j.cgh.2013.02.010_bib23","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1001\/archsurg.2009.36","article-title":"Current trends in pancreatic cystic neoplasms","volume":"144","author":"Ferrone","year":"2009","journal-title":"Arch Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib24","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1007\/s11605-007-0381-y","article-title":"Risk of malignancy in resected cystic tumors of the pancreas < or = 3 cm in size: is it safe to observe asymptomatic patients?","volume":"12","author":"Lee","year":"2008","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib25","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.cgh.2006.12.007","article-title":"Role of endoscopic ultrasound in the diagnosis of intraductal papillary mucinous neoplasms: correlation with surgical histopathology","volume":"5","author":"Pais","year":"2007","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2013.02.010_bib26","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1111\/j.1572-0241.2007.01224.x","article-title":"Do consensus indications for resection in branch duct intraductal papillary mucinous neoplasm predict malignancy?","volume":"102","author":"Pelaez-Luna","year":"2007","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2013.02.010_bib27","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1002\/cncy.20118","article-title":"High-grade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than \u201cpositive\u201d cytology","volume":"118","author":"Pitman","year":"2010","journal-title":"Cancer Cytopathol"},{"key":"10.1016\/j.cgh.2013.02.010_bib28","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1053\/j.gastro.2007.05.010","article-title":"Branch-duct intraductal papillary mucinous neoplasms: observations in 145 patients who underwent resection","volume":"133","author":"Rodriguez","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2013.02.010_bib29","doi-asserted-by":"crossref","first-page":"722","DOI":"10.2214\/AJR.08.1253","article-title":"Comparative performance of MDCT and MRI with MR cholangiopancreatography in characterizing small pancreatic cysts","volume":"193","author":"Sainani","year":"2009","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.cgh.2013.02.010_bib30","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1097\/01.sla.0000124386.54496.15","article-title":"Main-duct intraductal papillary mucinous neoplasms of the pancreas: clinical predictors of malignancy and long-term survival following resection","volume":"239","author":"Salvia","year":"2004","journal-title":"Ann Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib31","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s11605-007-0404-8","article-title":"PGE(2) in pancreatic cyst fluid helps differentiate IPMN from MCN and predict IPMN dysplasia","volume":"12","author":"Schmidt","year":"2008","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib32","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.cgh.2008.04.005","article-title":"Evaluation of the guidelines for management of pancreatic branch-duct intraductal papillary mucinous neoplasm","volume":"6","author":"Tang","year":"2008","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2013.02.010_bib33","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/j.crad.2006.04.008","article-title":"Intraductal papillary mucinous tumour of the pancreas: differentiation of malignancy and benignancy by CT","volume":"61","author":"Chiu","year":"2006","journal-title":"Clin Radiol"},{"key":"10.1016\/j.cgh.2013.02.010_bib34","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3348\/kjr.2003.4.3.157","article-title":"Differential diagnosis of benign and malignant intraductal papillary mucinous tumors of the pancreas: MR cholangiopancreatography and MR angiography","volume":"4","author":"Choi","year":"2003","journal-title":"Korean J Radiol"},{"key":"10.1016\/j.cgh.2013.02.010_bib35","doi-asserted-by":"crossref","first-page":"740","DOI":"10.3346\/jkms.2011.26.6.740","article-title":"Determination of malignant and invasive predictors in branch duct type intraductal papillary mucinous neoplasms of the pancreas: a suggested scoring formula","volume":"26","author":"Hwang","year":"2011","journal-title":"J Korean Med Sci"},{"key":"10.1016\/j.cgh.2013.02.010_bib36","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1245\/ASO.2005.02.030","article-title":"Multicenter analysis of clinicopathologic features of intraductal papillary mucinous tumor of the pancreas: is it possible to predict the malignancy before surgery?","volume":"12","author":"Jang","year":"2005","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cgh.2013.02.010_bib37","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1245\/s10434-007-9603-5","article-title":"Treatment guidelines for branch duct type intraductal papillary mucinous neoplasms of the pancreas: when can we operate or observe?","volume":"15","author":"Jang","year":"2008","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.cgh.2013.02.010_bib38","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.cgh.2010.09.008","article-title":"Cyst growth rate predicts malignancy in patients with branch duct intraductal papillary mucinous neoplasms","volume":"9","author":"Kang","year":"2011","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2013.02.010_bib39","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1002\/bjs.6557","article-title":"Branch duct intraductal papillary mucinous neoplasms in a retrospective series of 190 patients","volume":"96","author":"Woo","year":"2009","journal-title":"Br J Surg"},{"key":"10.1016\/j.cgh.2013.02.010_bib40","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1067\/msy.2000.106126","article-title":"Intraductal papillary mucinous tumors of the pancreas: pancreatic resections guided by preoperative morphological assessment and intraoperative frozen section examination","volume":"127","author":"Paye","year":"2000","journal-title":"Surgery"},{"key":"10.1016\/j.cgh.2013.02.010_bib41","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1097\/00000478-200010000-00006","article-title":"Intraductal papillary mucinous tumors of the pancreas confined to secondary ducts show less aggressive pathologic features as compared with those involving the main pancreatic duct","volume":"24","author":"Terris","year":"2000","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.cgh.2013.02.010_bib42","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1007\/s00261-004-0127-1","article-title":"Branch duct IPMTs: value of cross-sectional imaging in the assessment of biological behavior and follow-up","volume":"31","author":"Carbognin","year":"2006","journal-title":"Abdom Imaging"},{"key":"10.1016\/j.cgh.2013.02.010_bib43","doi-asserted-by":"crossref","first-page":"4037","DOI":"10.3748\/wjg.15.4037","article-title":"Imaging features of intraductal papillary mucinous neoplasms of the pancreas in multi-detector row computed tomography","volume":"15","author":"Tan","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cgh.2013.02.010_bib44","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1097\/00006676-200105000-00006","article-title":"Clinical management of intraductal papillary mucinous tumors of the pancreas based on imaging findings","volume":"22","author":"Wakabayashi","year":"2001","journal-title":"Pancreas"},{"key":"10.1016\/j.cgh.2013.02.010_bib45","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1038\/ajg.2010.122","article-title":"Prevalence of incidental pancreatic cysts in the adult population on MR imaging","volume":"105","author":"Lee","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2013.02.010_bib46","doi-asserted-by":"crossref","first-page":"802","DOI":"10.2214\/AJR.07.3340","article-title":"Prevalence of unsuspected pancreatic cysts on MDCT","volume":"191","author":"Laffan","year":"2008","journal-title":"AJR Am J Roentgenol"},{"key":"10.1016\/j.cgh.2013.02.010_bib47","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.cgh.2012.03.017","article-title":"Best practices in endoscopic ultrasound-guided fine-needle aspiration","volume":"10","author":"Varadarajulu","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2013.02.010_bib48","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.cgh.2012.09.019","article-title":"\u201cSystematic Reviews and Meta-analyses\u201d in clinical gastroenterology and hepatology","volume":"10","author":"Kanwal","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2013.02.010_bib49","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1007\/s11605-011-1437-6","article-title":"The duration of symptoms predicts the presence of malignancy in 210 resected cases of pancreatic intraductal papillary mucinous neoplasms","volume":"15","author":"Moriya","year":"2011","journal-title":"J Gastrointest Surg"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356513001870?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356513001870?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:11:36Z","timestamp":1761541896000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356513001870"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S1542356513001870"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2013.02.010","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cyst Features and Risk of Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Meta-Analysis","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2013.02.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 AGA Institute. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}