{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T17:27:19Z","timestamp":1790270839423,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.cgh.2015.10.010","type":"journal-article","created":{"date-parts":[[2015,10,23]],"date-time":"2015-10-23T19:38:59Z","timestamp":1445629139000},"page":"1619-1628","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":55,"title":["Nonalcoholic Steatohepatitis Is Associated With Increased Mortality in Obese Patients Undergoing Bariatric Surgery"],"prefix":"10.1016","volume":"14","author":[{"given":"Nicolas","family":"Goossens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujin","family":"Hoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Min","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2352-4774","authenticated-orcid":false,"given":"Minoa","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Morel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeki","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Louis","family":"Frossard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Spahr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott L.","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Negro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Rubbia-Brandt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiliano","family":"Giostra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2015.10.010_bib1","doi-asserted-by":"crossref","first-page":"w822","DOI":"10.1377\/hlthaff.28.5.w822","article-title":"Annual medical spending attributable to obesity: payer-and service-specific estimates","volume":"28","author":"Finkelstein","year":"2009","journal-title":"Health Aff"},{"key":"10.1016\/j.cgh.2015.10.010_bib2","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1001\/jama.2014.732","article-title":"Prevalence of childhood and adult obesity in the United States, 2011-2012","volume":"311","author":"Ogden","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.cgh.2015.10.010_bib3","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/S0140-6736(14)60460-8","article-title":"Global, regional, and national prevalence of overweight and obesity in children and adults during 1980\u20132013: a systematic analysis for the Global Burden of Disease Study","volume":"384","author":"Ng","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.cgh.2015.10.010_bib4","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1002\/hep.20466","article-title":"Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity","volume":"40","author":"Browning","year":"2004","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2015.10.010_bib5","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/nrgastro.2013.171","article-title":"The global NAFLD epidemic","volume":"10","author":"Loomba","year":"2013","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2015.10.010_bib6","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.jhep.2006.06.013","article-title":"Hepatic histology in obese patients undergoing bariatric surgery","volume":"45","author":"Machado","year":"2006","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cgh.2015.10.010_bib7","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1001\/jama.2014.10706","article-title":"Long-term follow-up after bariatric surgery: a systematic review","volume":"312","author":"Puzziferri","year":"2014","journal-title":"JAMA"},{"key":"10.1016\/j.cgh.2015.10.010_bib8","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1056\/NEJMoa066603","article-title":"Long-term mortality after gastric bypass surgery","volume":"357","author":"Adams","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cgh.2015.10.010_bib9","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1056\/NEJMoa066254","article-title":"Effects of bariatric surgery on mortality in Swedish obese subjects","volume":"357","author":"Sj\u00f6str\u00f6m","year":"2007","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cgh.2015.10.010_bib10","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1001\/jama.2011.817","article-title":"Survival among high-risk patients after bariatric surgery","volume":"305","author":"Maciejewski","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.cgh.2015.10.010_bib11","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1056\/NEJMoa0901836","article-title":"Perioperative safety in the longitudinal assessment of bariatric surgery","volume":"361","author":"Flum","year":"2009","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cgh.2015.10.010_bib12","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1007\/s11695-012-0663-7","article-title":"Systematic review of obesity surgery mortality risk score: preoperative risk stratification in bariatric surgery","volume":"22","author":"Thomas","year":"2012","journal-title":"Obes Surg"},{"key":"10.1016\/j.cgh.2015.10.010_bib13","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1097\/00000658-200211000-00007","article-title":"Male gender is a predictor of morbidity and age a predictor of mortality for patients undergoing gastric bypass surgery","volume":"236","author":"Livingston","year":"2002","journal-title":"Ann Surg"},{"key":"10.1016\/j.cgh.2015.10.010_bib14","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1001\/archsurg.2009.134","article-title":"Predictors of long-term mortality after bariatric surgery performed in veterans affairs medical centers","volume":"144","author":"Arterburn","year":"2009","journal-title":"Arch Surg"},{"key":"10.1016\/j.cgh.2015.10.010_bib15","first-page":"1568","article-title":"[Surgical treatment of obesity in 2006]","volume":"2","author":"Chassot","year":"2006","journal-title":"Rev Med Suisse"},{"key":"10.1016\/j.cgh.2015.10.010_bib16","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/hep.20701","article-title":"Design and validation of a histological scoring system for nonalcoholic fatty liver disease","volume":"41","author":"Kleiner","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2015.10.010_bib17","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1002\/hep.24127","article-title":"Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings","volume":"53","author":"Brunt","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2015.10.010_bib18","series-title":"National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey III, 1988-1994","year":"1998"},{"key":"10.1016\/j.cgh.2015.10.010_bib19","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1136\/gutjnl-2014-307862","article-title":"A\u00a0genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration","volume":"64","author":"King","year":"2014","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2015.10.010_bib20","doi-asserted-by":"crossref","first-page":"e15543","DOI":"10.1371\/journal.pone.0015543","article-title":"Nearest template prediction: a single-sample-based flexible class prediction with confidence assessment","volume":"5","author":"Hoshida","year":"2010","journal-title":"PloS One"},{"key":"10.1016\/j.cgh.2015.10.010_bib21","doi-asserted-by":"crossref","first-page":"046115","DOI":"10.1103\/PhysRevE.85.046115","article-title":"Building complex networks with platonic solids","volume":"85","author":"Song","year":"2012","journal-title":"Physical Review E"},{"key":"10.1016\/j.cgh.2015.10.010_bib22","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.1016\/j.dam.2011.07.018","article-title":"Nested hierarchies in planar graphs","volume":"159","author":"Song","year":"2011","journal-title":"Discrete Appl Math"},{"key":"10.1016\/j.cgh.2015.10.010_bib23","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1002\/hep.26661","article-title":"Hepatic gene expression profiles differentiate pre-symptomatic patients with mild versus severe nonalcoholic fatty liver disease","volume":"59","author":"Moylan","year":"2013","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2015.10.010_bib24","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1002\/hep.26898","article-title":"Epidermal growth factor receptor inhibition attenuates liver fibrosis and development of hepatocellular carcinoma","volume":"59","author":"Fuchs","year":"2014","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2015.10.010_bib25","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.bbamcr.2007.08.004","article-title":"Disruption of the latent transforming growth factor-beta binding protein-1 gene causes alteration in facial structure and influences TGF-beta bioavailability","volume":"1783","author":"Drews","year":"2008","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.cgh.2015.10.010_bib26","article-title":"A\u00a0hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection","author":"Zhang","year":"2015","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2015.10.010_bib27","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1053\/j.gastro.2009.04.052","article-title":"Prospective study of the long-term effects of bariatric surgery on liver injury in patients without advanced disease","volume":"137","author":"Mathurin","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.10.010_bib28","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1053\/j.gastro.2015.04.014","article-title":"Bariatric surgery reduces features of non-alcoholic steatohepatitis in morbidly obese patients","volume":"149","author":"Lassailly","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.10.010_bib29","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1053\/j.gastro.2015.04.043","article-title":"Liver fibrosis, but no other histologic features, is associated with long-term outcomes of patients with nonalcoholic fatty liver disease","volume":"149","author":"Angulo","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.10.010_bib30","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1002\/hep.27368","article-title":"Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up","volume":"61","author":"Ekstedt","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2015.10.010_bib31","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature10809","article-title":"Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity","volume":"482","author":"Henao-Mejia","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.cgh.2015.10.010_bib32","first-page":"343","article-title":"Non-alcoholic fatty liver disease and mortality among US adults: prospective cohort study","author":"Lazo","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.cgh.2015.10.010_bib33","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.jhep.2008.06.018","article-title":"Increased overall mortality and liver-related mortality in non-alcoholic fatty liver disease","volume":"49","author":"Ong","year":"2008","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cgh.2015.10.010_bib34","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jamcollsurg.2011.04.030","article-title":"Trends in use of bariatric surgery, 2003\u22122008","volume":"213","author":"Nguyen","year":"2011","journal-title":"J\u00a0Am Coll Surg"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356515014068?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356515014068?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:21:01Z","timestamp":1761542461000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356515014068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":34,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S1542356515014068"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2015.10.010","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nonalcoholic Steatohepatitis Is Associated With Increased Mortality in Obese Patients Undergoing Bariatric Surgery","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2015.10.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 by the AGA Institute","name":"copyright","label":"Copyright"}]}}