{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T15:01:29Z","timestamp":1771340489129,"version":"3.50.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.cgh.2015.12.047","type":"journal-article","created":{"date-parts":[[2016,1,22]],"date-time":"2016-01-22T00:02:21Z","timestamp":1453420941000},"page":"704-712.e4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":62,"title":["Targeted Biopsies Identify Larger Proportions of Patients With Colonic Neoplasia Undergoing High-Definition Colonoscopy, Dye Chromoendoscopy, or Electronic Virtual Chromoendoscopy"],"prefix":"10.1016","volume":"14","author":[{"given":"Miriam F.","family":"Gasia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subrata","family":"Ghosh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Remo","family":"Panaccione","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose G.","family":"Ferraz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilaad G.","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yvette","family":"Leung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerri L.","family":"Novak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cynthia H.","family":"Seow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marietta","family":"Iacucci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2015.12.047_bib1","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1136\/gut.48.4.526","article-title":"The risk of colorectal cancer in ulcerative colitis: a meta-analysis","volume":"48","author":"Eaden","year":"2001","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2015.12.047_bib2","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0140-6736(90)91889-I","article-title":"Increased risk of large-bowel cancer in Crohn's disease with colonic involvement","volume":"336","author":"Ekbom","year":"1990","journal-title":"Lancet"},{"issue":"Suppl 5","key":"10.1016\/j.cgh.2015.12.047_bib3","doi-asserted-by":"crossref","first-page":"V10","DOI":"10.1136\/gut.51.suppl_5.v10","article-title":"Guidelines for screening and surveillance of asymptomatic colorectal cancer in patients with inflammatory bowel disease","volume":"51","author":"Eaden","year":"2002","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2015.12.047_bib4","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1053\/gast.2003.50044","article-title":"Colorectal cancer screening and surveillance: clinical guidelines and rationale-update based on new evidence","volume":"124","author":"Winawer","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.12.047_bib5","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0016-5107(98)70062-8","article-title":"The role of colonoscopy in the management of patients with inflammatory bowel disease","volume":"48","year":"1998","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2015.12.047_bib6","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1053\/gast.2003.50146","article-title":"Methylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis","volume":"124","author":"Kiesslich","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.12.047_bib7","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1111\/j.1572-0241.2003.07580.x","article-title":"Chromoscopy might improve diagnostic accuracy in cancer surveillance for ulcerative colitis","volume":"98","author":"Matsumoto","year":"2003","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2015.12.047_bib8","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1136\/gut.2003.016386","article-title":"Pancolonic indigo carmine dye spraying for the detection of dysplasia in ulcerative colitis","volume":"53","author":"Rutter","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2015.12.047_bib9","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1111\/j.1572-0241.2008.01934.x","article-title":"Chromoendoscopy-targeted biopsies are superior to standard colonoscopic surveillance for detecting dysplasia in inflammatory bowel disease patients: a prospective endoscopic trial","volume":"103","author":"Marion","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2015.12.047_bib10","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1007\/s00384-011-1130-y","article-title":"Surveillance colonoscopy in patients with inflammatory bowel disease: comparison of random biopsy vs. targeted biopsy protocols","volume":"26","author":"Gunther","year":"2011","journal-title":"Int J Colorectal Dis"},{"key":"10.1016\/j.cgh.2015.12.047_bib11","first-page":"1913","article-title":"Procedure time and the determination of polypoid abnormalities with experience: implementation of a chromoendoscopy program for surveillance colonoscopy for ulcerative colitis","volume":"19","author":"Picco","year":"2013","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2015.12.047_bib12","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1365-2036.2010.04525.x","article-title":"Meta-analysis: the diagnostic yield of chromoendoscopy for detecting dysplasia in patients with colonic inflammatory bowel disease","volume":"33","author":"Subramanian","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2015.12.047_bib13","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1053\/j.gastro.2013.04.008","article-title":"The detection of nonpolypoid (flat and depressed) colorectal neoplasms in patients with inflammatory bowel disease","volume":"144","author":"Soetikno","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.12.047_bib14","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1053\/j.gastro.2015.01.031","article-title":"SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease","volume":"148","author":"Laine","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.12.047_bib15","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1038\/ajg.2015.63","article-title":"Chromoendoscopy for surveillance in inflammatory bowel disease does not increase neoplasia detection compared with conventional colonoscopy with random biopsies: results from a large retrospective study","volume":"110","author":"Mooiweer","year":"2015","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2015.12.047_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/S0016-5085(15)30256-0","article-title":"A randomized comparison of high definition colonoscopy alone with high definition dye spraying and electronic virtual chromoendoscopy using iSCAN for detection of colonic dysplastic lesions during IBD surveillance colonoscopy","volume":"148","author":"Iacucci","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.12.047_bib17","article-title":"High definition white light endoscopy (Hdwle) versus high definition with chromoendoscopy (Hdce) in the detection of dysplasia in long standing ulcerative colitis: a randomized controlled trial","volume":"81","author":"Noor","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2015.12.047_bib18","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1046\/j.1365-2036.2000.00698.x","article-title":"Colorectal cancer prevention in ulcerative colitis: a case-control study","volume":"14","author":"Eaden","year":"2000","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2015.12.047_bib19","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0016-5107(00)70405-6","article-title":"How gastroenterologists screen for colonic cancer in ulcerative colitis: an analysis of performance","volume":"51","author":"Eaden","year":"2000","journal-title":"Gastrointest Endosc"},{"issue":"Suppl 3","key":"10.1016\/j.cgh.2015.12.047_bib20","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1365-2036.2006.03062.x","article-title":"Review article: colorectal cancer surveillance in ulcerative colitis - what should we be doing?","volume":"24","author":"Obrador","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2015.12.047_bib21","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1155\/2014\/825947","article-title":"Novel diagnostic and therapeutic techniques for surveillance of dysplasia in patients with inflammatory bowel disease","volume":"28","author":"Iacucci","year":"2014","journal-title":"Can J Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2015.12.047_bib22","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1053\/j.gastro.2012.04.016","article-title":"Decreasing risk of colorectal cancer in patients with inflammatory bowel disease over 30 years","volume":"143","author":"Jess","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.12.047_bib23","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.jhep.2008.08.013","article-title":"High lifetime risk of cancer in primary sclerosing cholangitis","volume":"50","author":"Claessen","year":"2009","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cgh.2015.12.047_bib24","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1136\/gut.48.3.430","article-title":"Increased colorectal neoplasia in chronic ulcerative colitis complicated by primary sclerosing cholangitis: fact or fiction?","volume":"48","author":"Jayaram","year":"2001","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2015.12.047_bib25","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1155\/2014\/386540","article-title":"Serrated adenoma prevalence in inflammatory bowel disease surveillance colonoscopy, and characteristics revealed by chromoendoscopy and virtual chromoendoscopy","volume":"28","author":"Iacucci","year":"2014","journal-title":"Can J Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2015.12.047_bib26","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.dld.2009.04.005","article-title":"Recognition and characterization of small colonic neoplasia with high-definition colonoscopy using i-Scan is as precise as chromoendoscopy","volume":"42","author":"Hoffman","year":"2010","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.cgh.2015.12.047_bib27","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1053\/j.gastro.2006.12.038","article-title":"A\u00a0review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis","volume":"132","author":"D'Haens","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.12.047_bib28","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/S0016-5107(03)02159-X","article-title":"The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002","volume":"58","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2015.12.047_bib29","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/gut.47.2.251","article-title":"The Vienna classification of gastrointestinal epithelial neoplasia","volume":"47","author":"Schlemper","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2015.12.047_bib30","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1053\/j.gastro.2004.03.025","article-title":"Diagnosis and management of dysplasia in patients with inflammatory bowel diseases","volume":"126","author":"Itzkowitz","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2015.12.047_bib31","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/S0016-5107(04)01710-9","article-title":"Most dysplasia in ulcerative colitis is visible at colonoscopy","volume":"60","author":"Rutter","year":"2004","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2015.12.047_bib32","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0140-6736(94)90813-3","article-title":"Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis?","volume":"343","author":"Bernstein","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.cgh.2015.12.047_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.crohns.2012.09.005","article-title":"Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: special situations","volume":"7","author":"Van Assche","year":"2013","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1016\/j.cgh.2015.12.047_bib34","unstructured":"Marion JF. Chromoendoscopy: this is what progress looks like. AGA Perspect 2015;June\/July."},{"key":"10.1016\/j.cgh.2015.12.047_bib35","unstructured":"Ullman TA. Chromoendoscopy: still not ready for prime time. AGA Perspect 2015;June\/July."},{"key":"10.1016\/j.cgh.2015.12.047_bib36","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1038\/ajg.2015.179","article-title":"Editorial: miles to go on the SCENIC route: should chromoendoscopy become the standard of care in IBD surveillance?","volume":"110","author":"Higgins","year":"2015","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2015.12.047_bib37","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1055\/s-2005-921032","article-title":"Indigo carmine-assisted high-magnification chromoscopic colonoscopy for the detection and characterisation of intraepithelial neoplasia in ulcerative colitis: a prospective evaluation","volume":"37","author":"Hurlstone","year":"2005","journal-title":"Endoscopy"},{"key":"10.1016\/j.cgh.2015.12.047_bib38","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1055\/s-2007-966214","article-title":"Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis","volume":"39","author":"Dekker","year":"2007","journal-title":"Endoscopy"},{"key":"10.1016\/j.cgh.2015.12.047_bib39","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1055\/s-0030-1255956","article-title":"Narrow-band imaging versus high-definition endoscopy or the diagnosis of neoplasia in ulcerative colitis","volume":"43","author":"van den Broek","year":"2011","journal-title":"Endoscopy"},{"key":"10.1016\/j.cgh.2015.12.047_bib40","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.cgh.2015.04.172","article-title":"White-light or narrow-band imaging colonoscopy in surveillance of ulcerative colitis: a prospective multicenter study","volume":"13","author":"Leifeld","year":"2015","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356516000513?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356516000513?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:20:21Z","timestamp":1761542421000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356516000513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["S1542356516000513"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2015.12.047","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Targeted Biopsies Identify Larger Proportions of Patients With Colonic Neoplasia Undergoing High-Definition Colonoscopy, Dye Chromoendoscopy, or Electronic Virtual Chromoendoscopy","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2015.12.047","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The AGA Institute.","name":"copyright","label":"Copyright"}]}}