{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T01:51:27Z","timestamp":1789955487647,"version":"4.0.1"},"reference-count":53,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.cgh.2016.11.021","type":"journal-article","created":{"date-parts":[[2016,11,25]],"date-time":"2016-11-25T04:31:31Z","timestamp":1480048291000},"page":"1684-1697.e11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":76,"title":["Chromoendoscopy for Surveillance in Ulcerative Colitis and Crohn\u2019s Disease: A Systematic Review of Randomized Trials"],"prefix":"10.1016","volume":"15","author":[{"given":"Andrea","family":"Iannone","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marinella","family":"Ruospo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germaine","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariabeatrice","family":"Principi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8284-5127","authenticated-orcid":false,"given":"Michele","family":"Barone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni F.M.","family":"Strippoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Di Leo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2016.11.021_bib1","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.cgh.2012.01.010","article-title":"Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies","volume":"10","author":"Jess","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2016.11.021_bib2","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1111\/j.1572-0241.2005.00287.x","article-title":"Increased risk of intestinal cancer in Crohn\u2019s disease: a meta-analysis of population-based cohort studies","volume":"100","author":"Jess","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2016.11.021_bib3","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.cgh.2012.09.026","article-title":"Trends in overall and cause-specific mortality among patients with inflammatory bowel disease from 1982 to 2010","volume":"11","author":"Jess","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2016.11.021_bib4","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1053\/j.gastro.2003.11.010","article-title":"Severity of inflammation is a risk factor for colorectal neoplasia in ulcerative colitis","volume":"126","author":"Rutter","year":"2004","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib5","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1053\/j.gastro.2007.08.001","article-title":"Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study","volume":"133","author":"Gupta","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib6","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/his.12530","article-title":"The pathology of bowel cancer screening","volume":"66","author":"Loughrey","year":"2015","journal-title":"Histopathology"},{"key":"10.1016\/j.cgh.2016.11.021_bib7","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1053\/j.gastro.2009.12.037","article-title":"AGA medical position statement on the diagnosis and management of colorectal neoplasia in inflammatory bowel disease","volume":"138","author":"Farraye","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib8","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1016\/j.gie.2014.10.030","article-title":"The role of endoscopy in inflammatory bowel disease","volume":"81","author":"Shergill","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib9","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.crohns.2013.09.016","article-title":"European evidence based consensus for endoscopy in inflammatory bowel disease","volume":"7","author":"Annese","year":"2013","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1016\/j.cgh.2016.11.021_bib10","unstructured":"European Crohn's and Colitis Organisation. ECCO e-guide. Colorectal carcinoma surveillance, ulcerative colitis. Available from: http:\/\/www.e-guide.ecco-ibd.eu\/interventions-investigational\/colorectal-carcinoma-surveillance#ulcerative-colitis. Accessed: October 8,\u00a02016."},{"key":"10.1016\/j.cgh.2016.11.021_bib11","unstructured":"Connell W, Kamm M, Kench J, et\u00a0al. Cancer Council Australia Surveillance Colonoscopy Guidelines Working Party. Clinical practice guidelines for Surveillance Colonoscopy. Sydney: Cancer Council Australia. Available from: http:\/\/wiki.cancer.org.au\/australia\/Guidelines:Colorectal_cancer\/Colonoscopy_surveillance. Accessed: October 8,\u00a02016."},{"key":"10.1016\/j.cgh.2016.11.021_bib12","series-title":"Colonoscopic surveillance for prevention of colorectal cancer in people with ulcerative colitis, Crohn\u2019s disease or adenomas. National Institute for Health and Clinical Excellence (NICE) Clinical guideline","author":"Howdle","year":"2011"},{"key":"10.1016\/j.cgh.2016.11.021_bib13","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1055\/s-0034-1365348","article-title":"Advanced imaging for detection and differentiation of colorectal neoplasia: European Society of Gastrointestinal Endoscopy (ESGE) guideline","volume":"46","author":"Kami\u0144ski","year":"2014","journal-title":"Endoscopy"},{"key":"10.1016\/j.cgh.2016.11.021_bib14","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1097\/01.MIB.0000160811.76729.d5","article-title":"Consensus conference: colorectal cancer screening and surveillance in inflammatory bowel disease","volume":"11","author":"Itzkowitz","year":"2005","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2016.11.021_bib15","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/ajg.2008.168","article-title":"Management of Crohn's disease in adults","volume":"104","author":"Lichtenstein","year":"2009","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2016.11.021_bib16","first-page":"CD000279","article-title":"Strategies for detecting colon cancer and\/or dysplasia in patients with inflammatory bowel disease","volume":"2","author":"Collins","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.cgh.2016.11.021_bib17","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.1016\/0016-5085(92)91185-7","article-title":"DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis","volume":"103","author":"Rubin","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib18","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.gie.2006.09.025","article-title":"Are dysplasia and colorectal cancer endoscopically visible in patients with ulcerative colitis?","volume":"65","author":"Rubin","year":"2007","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib19","doi-asserted-by":"crossref","first-page":"274","DOI":"10.5946\/ce.2012.45.3.274","article-title":"Colonoscopic cancer surveillance in inflammatory bowel disease: what's new beyond random biopsy?","volume":"45","author":"East","year":"2012","journal-title":"Clin Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib20","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/ibd.23002","article-title":"Comparison of high definition with standard white light endoscopy for detection of dysplastic lesions during surveillance colonoscopy in patients with colonic inflammatory bowel disease","volume":"19","author":"Subramanian","year":"2013","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2016.11.021_bib21","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.gie.2014.12.009","article-title":"SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease","volume":"81","author":"Laine","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib22","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1055\/s-2007-966214","article-title":"Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis","volume":"39","author":"Dekker","year":"2007","journal-title":"Endoscopy"},{"key":"10.1016\/j.cgh.2016.11.021_bib23","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.cgh.2015.04.172","article-title":"White-light or narrow-band imaging colonoscopy in surveillance of ulcerative colitis: a prospective multicenter study","volume":"13","author":"Leifeld","year":"2015","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2016.11.021_bib24","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1136\/gut.2007.144097","article-title":"Endoscopic tri-modal imaging for surveillance in ulcerative colitis: randomised comparison of high-resolution endoscopy and autofluorescence imaging for neoplasia detection; and evaluation of narrow-band imaging for classification of lesions","volume":"57","author":"van den Broek","year":"2008","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2016.11.021_bib25","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1055\/s-0030-1255956","article-title":"Narrow-band imaging versus high-definition endoscopy for the diagnosis of neoplasia in ulcerative colitis","volume":"43","author":"van den Broek","year":"2011","journal-title":"Endoscopy"},{"key":"10.1016\/j.cgh.2016.11.021_bib26","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/ajg.2012.67","article-title":"Narrow band\u00a0imaging for detection of dysplasia in colitis: a randomized controlled trial","volume":"107","author":"Ignjatovic","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2016.11.021_bib27","first-page":"S129","article-title":"Final results of a randomized study comparing high definition colonoscopy alone with high definition dye spraying and electronic virtual chromoendoscopy using iSCAN for detection of colonic neoplastic lesions during IBD surveillance colonoscopy","volume":"150","author":"Iacucci","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib28","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1111\/j.1463-1318.2010.02505.x","article-title":"The diagnostic accuracy of chromoendoscopy for dysplasia in ulcerative colitis: meta-analysis of six randomized controlled trial","volume":"14","author":"Wu","year":"2012","journal-title":"Colorectal Dis"},{"key":"10.1016\/j.cgh.2016.11.021_bib29","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.gie.2013.10.026","article-title":"Cost-effectiveness analysis of chromoendoscopy for colorectal cancer surveillance in patients with ulcerative colitis","volume":"79","author":"Konijeti","year":"2014","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib30","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1365-2036.2010.04525.x","article-title":"Meta-analysis: the diagnostic yield of chromoendoscopy for detecting dysplasia in patients with colonic inflammatory bowel disease","volume":"33","author":"Subramanian","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2016.11.021_bib31","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1136\/gut.2010.224154","article-title":"Guidelines for the management of inflammatory bowel disease in adults","volume":"60","author":"Mowat","year":"2011","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2016.11.021_bib32","unstructured":"European Crohn's and Colitis Organisation. ECCO e-guide. Colorectal carcinoma surveillance, Crohn\u2019s disease. Available from: http:\/\/www.e-guide.ecco-ibd.eu\/interventions-investigational\/colorectal-carcinoma-surveillance#crohnsdisease. Accessed: October 8,\u00a02016."},{"key":"10.1016\/j.cgh.2016.11.021_bib33","doi-asserted-by":"crossref","first-page":"264","DOI":"10.7326\/0003-4819-151-4-200908180-00135","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"151","author":"Moher","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.cgh.2016.11.021_bib34","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.crohns.2013.06.001","article-title":"European consensus on the histopathology of inflammatory bowel disease","volume":"7","author":"Magro","year":"2013","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1016\/j.cgh.2016.11.021_bib35","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/S0016-5107(03)02159-X","article-title":"The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002","volume":"58","year":"2003","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib36","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/gut.47.2.251","article-title":"The Vienna classification of gastrointestinal epithelial neoplasia","volume":"47","author":"Schlemper","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2016.11.021_bib37","first-page":"1353","article-title":"Serrated and microtubular colorectal adenomas in Italian patients. A 5-year survey","volume":"25","author":"Rubio","year":"2005","journal-title":"Anticancer Res"},{"key":"10.1016\/j.cgh.2016.11.021_bib38","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.cgh.2016.11.021_bib39","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.cgh.2016.11.021_bib40","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1053\/gast.2003.50146","article-title":"Methylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis","volume":"124","author":"Kiesslich","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib41","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1053\/j.gastro.2007.01.048","article-title":"Chromoscopy-guided endomicroscopy increases the diagnostic yield of intraepithelial neoplasia in ulcerative colitis","volume":"132","author":"Kiesslich","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib42","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1097\/00054725-201112002-00045","article-title":"Narrow-band imaging and chromoendoscopy for the detection of colonic dysplasia in inflammatory bowel disease: a prospective and randomized study","volume":"17","author":"Feitosa","year":"2011","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2016.11.021_bib43","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.gie.2011.05.013","article-title":"Narrow-band imaging as an alternative to chromoendoscopy for\u00a0the detection of dysplasia in long-standing inflammatory bowel disease: a prospective, randomized, crossover study","volume":"74","author":"Pellis\u00e9","year":"2011","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib44","doi-asserted-by":"crossref","first-page":"AB148","DOI":"10.1016\/j.gie.2012.04.082","article-title":"Chromo-endoscopy versus narrow band imaging in ulcerative colitis: a prospective randomized controlled trial","volume":"75","author":"Bisschops","year":"2012","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib45","doi-asserted-by":"crossref","first-page":"2038","DOI":"10.1097\/MIB.0000000000000176","article-title":"Surveillance in ulcerative colitis: is chromoendoscopy-guided endomicroscopy always better than conventional colonoscopy? A randomized trial","volume":"20","author":"Freire","year":"2014","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2016.11.021_bib46","doi-asserted-by":"crossref","first-page":"AB148","DOI":"10.1016\/j.gie.2015.03.1237","article-title":"High definition white light endoscopy (Hdwle) versus high definition with chromoendoscopy (Hdce) in the detection of dysplasia in long standing ulcerative colitis: a randomized controlled trial","volume":"81","author":"Mohammed","year":"2015","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib47","doi-asserted-by":"crossref","first-page":"S1270","DOI":"10.1016\/S0016-5085(16)34290-1","article-title":"High definition chromoendoscopy with water-jet versus high definition white light endoscopy in the detection of dysplasia in long standing ulcerative colitis: a multicenter prospective randomized controlled study","volume":"150","author":"Park","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib48","doi-asserted-by":"crossref","first-page":"AB172","DOI":"10.1016\/j.gie.2016.03.147","article-title":"Comparison between newly-developed narrow band imaging and panchromoendoscopy for surveillance colonoscopy in patients with longstanding ulcerative colitis: a prospective multicenter randomized controlled trial, navigator study","volume":"83","author":"Watanabe","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2016.11.021_bib49","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.cgh.2013.06.015","article-title":"Advanced endoscopic imaging: a review of commercially available technologies","volume":"12","author":"Subramanian","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2016.11.021_bib50","doi-asserted-by":"crossref","first-page":"222","DOI":"10.3109\/00365521.2013.863964","article-title":"Image-enhanced, chromo, and cap-assisted colonoscopy for improving adenoma\/neoplasia detection rate: a systematic review and meta-analysis","volume":"49","author":"Omata","year":"2014","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.cgh.2016.11.021_bib51","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1136\/gut.2006.107300","article-title":"Methylene blue but not indigo carmine causes DNA damage to colonocytes in\u00a0vitro and in\u00a0vivo at concentrations used in clinical chromoendoscopy","volume":"56","author":"Davies","year":"2007","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2016.11.021_bib52","doi-asserted-by":"crossref","first-page":"S827","DOI":"10.1016\/S0016-5085(15)32815-8","article-title":"Effect of oral administration of methylene blue MMx\u00ae tablets on double-stranded DNA damage assessed by \u03b3H2AX analysis of colon biopsy samples - a single center, open label, safety, phase II study","volume":"148","author":"Repici","year":"2015","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2016.11.021_bib53","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1055\/s-0042-102251","article-title":"In\u00a0vivo real-time assessment of colorectal polyp histology using an optical biopsy forceps system based on laser-induced fluorescence spectroscopy","volume":"48","author":"Rath","year":"2016","journal-title":"Endoscopy"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356516311193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356516311193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:23:26Z","timestamp":1761542606000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356516311193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":53,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S1542356516311193"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2016.11.021","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chromoendoscopy for Surveillance in Ulcerative Colitis and Crohn\u2019s Disease: A Systematic Review of Randomized Trials","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2016.11.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2017.09.001","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by the AGA Institute","name":"copyright","label":"Copyright"}]}}