{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:19:44Z","timestamp":1791559184901,"version":"4.3.4"},"reference-count":35,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,2,1]],"date-time":"2019-02-01T00:00:00Z","timestamp":1548979200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2019,2]]},"DOI":"10.1016\/j.cgh.2018.04.046","type":"journal-article","created":{"date-parts":[[2018,4,26]],"date-time":"2018-04-26T14:22:02Z","timestamp":1524752522000},"page":"440-447.e2","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Previous Use of Antithrombotic Agents Reduces Mortality and Length of Hospital Stay in Patients With High-risk Upper Gastrointestinal Bleeding"],"prefix":"10.1016","volume":"17","author":[{"given":"Philip D.J.","family":"Dunne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stig B.","family":"Laursen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loren","family":"Laine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry R.","family":"Dalton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing H.","family":"Ngu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Schultz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Anderloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain A.","family":"Murray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian J.","family":"Stanley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2018.04.046_bib1","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1136\/bmj.311.6999.222","article-title":"Incidence of and mortality from acute upper gastrointestinal haemorrhage in the UK","volume":"311","author":"Rockall","year":"1995","journal-title":"BMJ"},{"key":"10.1016\/j.cgh.2018.04.046_bib2","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1136\/bmj.315.7107.510","article-title":"Acute upper gastrointestinal haemorrhage in west of Scotland: case ascertainment study","volume":"315","author":"Blatchford","year":"1997","journal-title":"BMJ"},{"key":"10.1016\/j.cgh.2018.04.046_bib3","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1136\/gut.2010.228437","article-title":"Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit","volume":"60","author":"Hearnshaw","year":"2011","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2018.04.046_bib4","doi-asserted-by":"crossref","first-page":"h1585","DOI":"10.1136\/bmj.h1585","article-title":"Risk of gastrointestinal bleeding associated with oral anticoagulants: population based retrospective cohort study","volume":"350","author":"Chang","year":"2015","journal-title":"BMJ"},{"key":"10.1016\/j.cgh.2018.04.046_bib5","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.amjmed.2010.12.022","article-title":"Long term use of aspirin and the risk of gastrointestinal bleeding","volume":"124","author":"Huang","year":"2011","journal-title":"Am J Med"},{"key":"10.1016\/j.cgh.2018.04.046_bib6","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1016\/S0002-9270(00)01040-6","article-title":"Risk of upper gastrointestinal bleeding associated with use of low-dose aspirin","volume":"95","author":"S\u00f8rensen","year":"2000","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib7","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.3748\/wjg.v11.i9.1365","article-title":"Acute upper gastrointestinal bleeding in patients on long-term oral anticoagulation therapy: endoscopic findings, clinical management and outcome","volume":"11","author":"Thomopoulos","year":"2005","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib8","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.3109\/00365521.2010.510567","article-title":"Impact of aspirin, NSAIDs, warfarin, corticosteroids and SSRIs on the site and outcome of non-variceal upper and lower gastrointestinal bleeding","volume":"45","author":"Ashberg","year":"2010","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib9","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1136\/gut.38.3.316","article-title":"Risk assessment after\u00a0acute upper gastrointestinal haemorrhage","volume":"38","author":"Rockall","year":"1996","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2018.04.046_bib10","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1038\/ajg.2009.687","article-title":"For the Italian registry on\u00a0upper gastrointestinal bleeding. Predicting mortality in non-variceal upper gastrointestinal bleeders: validation of the Italian PNED score and prospective comparison with the Rockall score","volume":"105","author":"Marmo","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib11","first-page":"1842","article-title":"A\u00a0scoring system to predict rebleeding after endoscopic therapy of non-variceal upper gastrointestinal hemorrhage","volume":"88","author":"Saeed","year":"1993","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib12","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/S0140-6736(00)02816-6","article-title":"A\u00a0risk score to predict need for treatment for upper gastrointestinal haemorrhage","volume":"356","author":"Blatchford","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.cgh.2018.04.046_bib13","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.gie.2011.06.024","article-title":"A\u00a0simple risk score accurately predicts in hospital mortality, length of stay and cost in acute upper GI bleeding","volume":"74","author":"Saltzman","year":"2011","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.cgh.2018.04.046_bib14","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1053\/j.gastro.2007.10.037","article-title":"Artificial neural network as a predictive instrument in patients with acute non-variceal upper gastrointestinal hemorrhage","volume":"134","author":"Das","year":"2008","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2018.04.046_bib15","doi-asserted-by":"crossref","first-page":"i6432","DOI":"10.1136\/bmj.i6432","article-title":"Comparison of risk scoring systems for patients presenting with upper gastrointestinal bleeding: international multicentre prospective study","volume":"356","author":"Stanley","year":"2017","journal-title":"BMJ"},{"key":"10.1016\/j.cgh.2018.04.046_bib16","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/00000542-194105000-00004","article-title":"Grading of patients for surgical procedures","volume":"2","author":"Saklad","year":"1941","journal-title":"Anesthesiology"},{"key":"10.1016\/j.cgh.2018.04.046_bib17","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/ajg.2009.702","article-title":"Methodology for randomized trials of patients with nonvariceal upper gastrointestinal bleeding: recommendations from an international consensus conference","volume":"105","author":"Laine","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib18","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/S0140-6736(74)91770-X","article-title":"Endoscopy in gastrointestinal bleeding","volume":"2","author":"Forrest","year":"1974","journal-title":"Lancet"},{"key":"10.1016\/j.cgh.2018.04.046_bib19","doi-asserted-by":"crossref","first-page":"101","DOI":"10.7326\/0003-4819-152-2-201001190-00009","article-title":"International consensus recommendations on the management of patients with non-variceal upper gastrointestinal bleeding","volume":"152","author":"Barkun","year":"2010","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.cgh.2018.04.046_bib20","series-title":"Acute upper gastrointestinal bleeding: management. Clinical Guideline 141","year":"2012"},{"key":"10.1016\/j.cgh.2018.04.046_bib21","first-page":"1","article-title":"Non-variceal upper gastrointestinal haemorrhage: ESGE Guidelines","volume":"47","author":"Gralnek","year":"2015","journal-title":"Endoscopy"},{"key":"10.1016\/j.cgh.2018.04.046_bib22","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/ajg.2011.480","article-title":"Management of patients with ulcer bleeding, ACG Practice guidelines","volume":"107","author":"Laine","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib23","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.jhep.2010.06.004","article-title":"Revising consensus on portal hypertension: report of the Baveno V consensus workshop on methodology of diagnosis and therapy of portal hypertension","volume":"53","author":"De Franchis","year":"2010","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.cgh.2018.04.046_bib24","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJMoa1211801","article-title":"Transfusion strategies for acute upper gastrointestinal bleeding","volume":"368","author":"Villanueva","year":"2013","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cgh.2018.04.046_bib25","series-title":"Acute upper gastrointestinal bleeding in over 16s: management","year":"2012"},{"key":"10.1016\/j.cgh.2018.04.046_bib26","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.cgh.2014.07.023","article-title":"Performance of new thresholds of the GBS in managing patients with upper GI bleeding","volume":"13","author":"Laursen","year":"2015","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2018.04.046_bib27","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1111\/j.1537-2995.2012.03849.x","article-title":"Prevalence, management, and outcomes of patients with coagulopathy after acute nonvariceal upper gastrointestinal bleeding in the United Kingdom","volume":"53","author":"Jairath","year":"2013","journal-title":"Transfusion"},{"key":"10.1016\/j.cgh.2018.04.046_bib28","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1097\/EDE.0b013e3182576cdb","article-title":"Missing data: a systematic review of how they are reported and handled","volume":"23","author":"Eekhout","year":"2012","journal-title":"Epidemiology"},{"key":"10.1016\/j.cgh.2018.04.046_bib29","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/ajg.2009.507","article-title":"Causes of mortality in patients with peptic ulcer bleeding: a prospective cohort study of 10,428 cases","volume":"105","author":"Sung","year":"2010","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib30","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/hep.27783","article-title":"Impact of anticoagulation on upper-gastrointestinal bleeding in cirrhosis. A retrospective multicenter study","volume":"62","author":"Cerini","year":"2015","journal-title":"Hepatology"},{"key":"10.1016\/j.cgh.2018.04.046_bib31","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1038\/ajg.2014.398","article-title":"The risks of thromboembolism vs. recurrent gastrointestinal bleeding after interruption of systemic anticoagulation in hospitalized in patients with gastrointestinal bleeding: a prospective study","volume":"110","author":"Sengupta","year":"2015","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.04.046_bib32","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1001\/archinternmed.2012.4261","article-title":"Risk of thromboembolism, recurrent hemorrhage, and death after warfarin therapy interruption for gastrointestinal tract bleeding","volume":"172","author":"Witt","year":"2012","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.cgh.2018.04.046_bib33","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1136\/postgradmedj-2017-135276","article-title":"Stopping antithrombotic therapy after acute upper gastrointestinal bleeding is associated with reduced survival","volume":"94","author":"Siau","year":"2018","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.cgh.2018.04.046_bib34","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.amjcard.2013.10.044","article-title":"Restarting anticoagulation and outcomes after major gastrointestinal bleeding in atrial fibrillation","volume":"113","author":"Qureshi","year":"2014","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.cgh.2018.04.046_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/0003-4819-152-1-201001050-00179","article-title":"Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial","volume":"152","author":"Sung","year":"2010","journal-title":"Ann Intern Med"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356518304087?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356518304087?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:26:26Z","timestamp":1761542786000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356518304087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["S1542356518304087"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2018.04.046","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2019,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Previous Use of Antithrombotic Agents Reduces Mortality and Length of Hospital Stay in Patients With High-risk Upper Gastrointestinal Bleeding","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2018.04.046","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the AGA Institute","name":"copyright","label":"Copyright"}]}}