{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:09:40Z","timestamp":1791864580625,"version":"4.3.4"},"reference-count":45,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.cgh.2018.12.021","type":"journal-article","created":{"date-parts":[[2018,12,21]],"date-time":"2018-12-21T19:58:20Z","timestamp":1545422300000},"page":"1265-1275.e8","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Clinical Parameters Correlate With Endoscopic Activity of Ulcerative Colitis: A Systematic Review"],"prefix":"10.1016","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0646-3439","authenticated-orcid":false,"given":"Sophie","family":"Restellini","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Che-Yung","family":"Chao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myriam","family":"Martel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Barkun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Kherad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest","family":"Seidman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Wild","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Bitton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waqqas","family":"Afif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talat","family":"Bessissow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter L.","family":"Lakatos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2018.12.021_bib1","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1111\/apt.13408","article-title":"Development of interim patient-reported outcome measures for the assessment of ulcerative colitis disease activity in clinical trials","volume":"42","author":"Jairath","year":"2015","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2018.12.021_bib2","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1038\/ajg.2015.233","article-title":"Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): determining therapeutic goals for treat-to-target","volume":"110","author":"Peyrin-Biroulet","year":"2015","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.12.021_bib3","doi-asserted-by":"crossref","first-page":"2124","DOI":"10.1111\/j.1572-0241.1998.00607.x","article-title":"Correlation between endoscopic severity and the clinical activity index in ulcerative colitis","volume":"93","author":"Seo","year":"1998","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.12.021_bib4","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1136\/gut.43.1.29","article-title":"A\u00a0simple clinical colitis activity index","volume":"43","author":"Walmsley","year":"1998","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2018.12.021_bib5","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1053\/j.gastro.2007.05.029","article-title":"Development, validation, and evaluation of a pediatric ulcerative colitis activity index: a prospective multicenter study","volume":"133","author":"Turner","year":"2007","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2018.12.021_bib6","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1056\/NEJM199406303302601","article-title":"Cyclosporine in severe ulcerative colitis refractory to steroid therapy","volume":"330","author":"Lichtiger","year":"1994","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cgh.2018.12.021_bib7","first-page":"373","article-title":"Endoscopic assess-ment of the colonic response to corticosteroids in children with ulcerative colitis","volume":"22","author":"Beattie","year":"1996","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1016\/j.cgh.2018.12.021_bib8","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1056\/NEJM198712243172603","article-title":"Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study","volume":"317","author":"Schroeder","year":"1987","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.cgh.2018.12.021_bib9","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1136\/bmj.298.6666.82","article-title":"Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial","volume":"298","author":"Rachmilewitz","year":"1989","journal-title":"BMJ"},{"key":"10.1016\/j.cgh.2018.12.021_bib10","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1016\/0016-5085(87)90621-4","article-title":"5-Aminosalicylic acid enema in the treatment of distal ulcerative colitis, proctosigmoiditis, and proctitis","volume":"92","author":"Sutherland","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2018.12.021_bib11","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/BF01296733","article-title":"Correlations between defined sigmoidoscopic appearances and other measures of disease activity in ulcerative colitis","volume":"27","author":"Powell-Tuck","year":"1982","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.cgh.2018.12.021_bib12","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s10620-005-1590-4","article-title":"Proposal of a new clinical index predictive of endoscopic severity in ulcerative colitis","volume":"50","author":"Azzolini","year":"2005","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.cgh.2018.12.021_bib13","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.cgh.2015.06.001","article-title":"Defining disease severity in inflammatory bowel diseases: current and future directions","volume":"14","author":"Peyrin-Biroulet","year":"2016","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2018.12.021_bib14","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1136\/gutjnl-2011-300486","article-title":"Developing an instrument to assess the endoscopic severity of ulcerative colitis: the Ulcerative Colitis Endoscopic Index of Severity (UCEIS)","volume":"61","author":"Travis","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2018.12.021_bib15","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1002\/ibd.21480","article-title":"Measurement of disease activity in ulcerative colitis: interobserver agreement and predictors of severity","volume":"17","author":"Thia","year":"2011","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2018.12.021_bib16","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.cgh.2015.06.001","article-title":"Defining disease severity in inflammatory bowel diseases: current and future directions","volume":"14","author":"Peyrin-Biroulet","year":"2016","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2018.12.021_bib17","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.cgh.2018.06.015","article-title":"Patient-reported outcomes and endoscopic appearance of ulcerative colitis-a systematic review and meta-analysis","volume":"17","author":"Narula","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2018.12.021_bib18","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1136\/bmj.1.5375.89","article-title":"Variation between observers in describing mucosal appearances in proctocolitis","volume":"1","author":"Baron","year":"1964","journal-title":"Br Med J"},{"key":"10.1016\/j.cgh.2018.12.021_bib19","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1002\/ibd.20520","article-title":"Use of the noninvasive components of the Mayo score to assess clinical response in ulcerative colitis","volume":"14","author":"Lewis","year":"2008","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2018.12.021_bib20","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1002\/ibd.22879","article-title":"Can endoscopy be avoided in the assessment of ulcerative colitis in clinical trials?","volume":"18","author":"Dhanda","year":"2012","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2018.12.021_bib21","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1111\/apt.13387","article-title":"Randomised clinical study: discrepancies between patient-reported outcomes and endoscopic appearance in moderate to severe ulcerative colitis","volume":"42","author":"Jharap","year":"2015","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2018.12.021_bib22","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1136\/gutjnl-2016-312307","article-title":"Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC","volume":"66","author":"Colombel","year":"2017","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2018.12.021_bib23","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1097\/MEG.0000000000000461","article-title":"Clinical application of faecal calprotectin in ulcerative colitis patients","volume":"27","author":"Scaioli","year":"2015","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2018.12.021_bib24","first-page":"16","article-title":"Clinical, biological and epidemiological aspects of inflammatory bowel diseases in North-East Romania","volume":"117","author":"Achitei","year":"2013","journal-title":"Rev Med Chir Soc Med Nat Iasi"},{"key":"10.1016\/j.cgh.2018.12.021_bib25","first-page":"74","article-title":"Evaluation of relationship between clinical and colonoscopic features in patients with active ulcerative colitis","volume":"26","author":"Mirpour","year":"2007","journal-title":"Indian J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.12.021_bib26","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s10620-016-4397-6","article-title":"High percentage of IBD patients with indefinite fecal calprotectin levels: additional value of a combination score","volume":"62","author":"Bodelier","year":"2017","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.cgh.2018.12.021_bib27","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1002\/ibd.20986","article-title":"Ulcerative colitis: correlation of the Rachmilewitz endoscopic activity index with fecal calprotectin, clinical activity, c-reactive protein, and blood leukocytes","volume":"15","author":"Schoepfer","year":"2009","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2018.12.021_bib28","first-page":"3674","article-title":"Application of clinical indexes in ulcerative colitis patients in regular follow-up visit: correlation with endoscopic 'mucosal healing' and implication for management. Preliminary results","volume":"19","author":"Pagnini","year":"2015","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.cgh.2018.12.021_bib29","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1443-1661.2009.00916.x","article-title":"Validity of activity indices in ulcerative colitis: comparison of clinical and endoscopic indices","volume":"22","author":"Hirai","year":"2010","journal-title":"Dig Endosc"},{"key":"10.1016\/j.cgh.2018.12.021_bib30","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1111\/j.1572-0241.2007.01556.x","article-title":"Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-Elastase, CRP, and clinical indices","volume":"103","author":"Langhorst","year":"2008","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.12.021_bib31","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1093\/ecco-jcc\/jjw104","article-title":"The ulcerative colitis endoscopic index of severity is useful to predict medium- to long-term prognosis in ulcerative colitis patients with clinical remission","volume":"10","author":"Arai","year":"2016","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1016\/j.cgh.2018.12.021_bib32","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1572-0241.2005.40641.x","article-title":"Is endoscopy necessary for the measurement of disease activity in ulcerative colitis?","volume":"100","author":"Higgins","year":"2005","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.12.021_bib33","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.3109\/00365521.2011.584897","article-title":"Evaluation of disease activity in IBD at the time of diagnosis by the use of clinical, biochemical, and fecal markers","volume":"46","author":"Ricanek","year":"2011","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.12.021_bib34","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.cgh.2012.08.003","article-title":"Validation of the ulcerative colitis colonoscopic index of severity and its correlation with disease activity measures","volume":"11","author":"Samuel","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2018.12.021_bib35","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1007\/s10620-016-4180-8","article-title":"Clinical activity and quality of life indices are valid across ulcerative colitis but not Crohn's disease phenotypes","volume":"61","author":"Taleban","year":"2016","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.cgh.2018.12.021_bib36","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1097\/MIB.0000000000000341","article-title":"Disease activity assessment in IBD: clinical indices and biomarkers fail to predict endoscopic remission","volume":"21","author":"Falvey","year":"2015","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2018.12.021_bib37","doi-asserted-by":"crossref","first-page":"8235","DOI":"10.3748\/wjg.v23.i46.8235","article-title":"Efficacy of noninvasive evaluations in monitoring inflammatory bowel disease activity: a prospective study in China","volume":"23","author":"Chen","year":"2017","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.12.021_bib38","doi-asserted-by":"crossref","first-page":"661","DOI":"10.5056\/jnm15160","article-title":"Prevalence of irritable bowel syndrome-like symptoms in Japanese patients with inactive inflammatory bowel disease","volume":"22","author":"Tomita","year":"2016","journal-title":"J\u00a0Neurogastroenterol Motil"},{"key":"10.1016\/j.cgh.2018.12.021_bib39","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1136\/gutjnl-2011-300430","article-title":"Ulcerative colitis as a sole mucosal disease: another misunderstanding?","volume":"61","author":"Torres","year":"2012","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2018.12.021_bib40","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1365-2036.2006.03205.x","article-title":"The quantitative validation of non-endoscopic disease activity indices in ulcerative colitis","volume":"25","author":"Higgins","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2018.12.021_bib41","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1053\/gast.2001.20912","article-title":"Clinical, biological, and histologic parameters as predictors of relapse in ulcerative colitis","volume":"120","author":"Bitton","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2018.12.021_bib42","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1038\/ajg.2012.301","article-title":"Prognostic value of serologic and histologic markers on clinical relapse in ulcerative colitis patients with mucosal healing","volume":"107","author":"Bessissow","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2018.12.021_bib43","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1016\/j.crohns.2014.08.011","article-title":"Systematic review: histological remission in inflammatory bowel disease. Is 'complete' remission the new treatment paradigm? An IOIBD initiative","volume":"8","author":"Bryant","year":"2014","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1016\/j.cgh.2018.12.021_bib44","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1097\/MIB.0000000000000057","article-title":"Meta-analysis: fecal calprotectin for assessment of inflammatory bowel disease activity","volume":"20","author":"Lin","year":"2014","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2018.12.021_bib45","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1007\/s10620-018-4980-0","article-title":"Fecal calprotectin in assessing endoscopic and histological remission in patients\u00a0with ulcerative colitis","volume":"63","author":"Mak","year":"2018","journal-title":"Dig Dis Sci"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356518313971?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356518313971?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:27:54Z","timestamp":1761542874000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356518313971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":45,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S1542356518313971"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2018.12.021","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical Parameters Correlate With Endoscopic Activity of Ulcerative Colitis: A Systematic Review","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2018.12.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 by the AGA Institute","name":"copyright","label":"Copyright"}]}}