{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T11:23:58Z","timestamp":1792581838159,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T00:00:00Z","timestamp":1586304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.cgh.2020.03.060","type":"journal-article","created":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T11:26:16Z","timestamp":1586172376000},"page":"699-706.e4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Improvements in Dysphagia and Pain With Swallowing in Patients With Eosinophilic Esophagitis Receiving Budesonide Oral Suspension"],"prefix":"10.1016","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1167-1101","authenticated-orcid":false,"given":"Evan S.","family":"Dellon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0756-5974","authenticated-orcid":false,"given":"Margaret H.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Katzka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacie","family":"Hudgens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Lan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Vera-Llonch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7688-9377","authenticated-orcid":false,"given":"Ikuo","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2020.03.060_bib1","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1177\/2050640616689525","article-title":"Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults","volume":"5","author":"Lucendo","year":"2017","journal-title":"United European Gastroenterol J"},{"key":"10.1016\/j.cgh.2020.03.060_bib2","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1053\/j.gastro.2018.07.009","article-title":"Updated international consensus diagnostic criteria for eosinophilic esophagitis: proceedings of the AGREE conference","volume":"155","author":"Dellon","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2020.03.060_bib3","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.cgh.2014.05.021","article-title":"Efficacy and safety of oral budesonide suspension in pediatric patients with eosinophilic esophagitis","volume":"13","author":"Gupta","year":"2015","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2020.03.060_bib4","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.cgh.2012.03.018","article-title":"Swallowed fluticasone improves histologic but not symptomatic response of adults with eosinophilic esophagitis","volume":"10","author":"Alexander","year":"2012","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2020.03.060_bib5","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1053\/j.gastro.2015.11.004","article-title":"Symptoms have modest accuracy in detecting endoscopic and histologic remission in adults with eosinophilic esophagitis","volume":"150","author":"Safroneeva","year":"2016","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2020.03.060_bib6","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/j.cgh.2018.06.005","article-title":"Heterogeneity in clinical, endoscopic, and histologic outcome measures and placebo response rates in clinical trials of eosinophilic esophagitis: a systematic review","volume":"16","author":"Ma","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2020.03.060_bib7","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/j.cgh.2009.08.030","article-title":"Clinical, endoscopic, and histologic findings distinguish eosinophilic esophagitis from gastroesophageal reflux disease","volume":"7","author":"Dellon","year":"2009","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2020.03.060_bib8","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1111\/apt.12413","article-title":"Development and field testing of a novel patient-reported outcome measure of dysphagia in patients with eosinophilic esophagitis","volume":"38","author":"Dellon","year":"2013","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2020.03.060_bib9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/s41687-017-0006-5","article-title":"Psychometric validation of the Dysphagia Symptom Questionnaire in eosinophilic esophagitis patients treated with oral budesonide suspension","volume":"1","author":"Hudgens","year":"2017","journal-title":"J\u00a0Patient Rep Outcomes"},{"key":"10.1016\/j.cgh.2020.03.060_bib10","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1053\/j.gastro.2016.11.021","article-title":"Budesonide oral suspension improves symptomatic, endoscopic, and histologic parameters compared with placebo in patients with eosinophilic esophagitis","volume":"152","author":"Dellon","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2020.03.060_bib11","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.cgh.2018.05.051","article-title":"Safety and efficacy of budesonide oral suspension for maintenance therapy in patients with eosinophilic esophagitis","volume":"17","author":"Dellon","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2020.03.060_bib12","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.jaci.2011.02.040","article-title":"Eosinophilic esophagitis: updated consensus recommendations for children and adults","volume":"128","author":"Liacouras","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.cgh.2020.03.060_bib13","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/ajg.2013.71","article-title":"ACG clinical guideline: evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE)","volume":"108","author":"Dellon","year":"2013","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2020.03.060_bib14","first-page":"1","article-title":"Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring","volume":"30","author":"Collins","year":"2017","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.cgh.2020.03.060_bib15","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1136\/gutjnl-2011-301817","article-title":"Endoscopic assessment of the oesophageal features of eosinophilic oesophagitis: validation of a novel classification and grading system","volume":"62","author":"Hirano","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2020.03.060_bib16","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1007\/s10620-017-4642-7","article-title":"Six-food elimination diet and topical steroids are effective for eosinophilic esophagitis: a meta-regression","volume":"62","author":"Cotton","year":"2017","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.cgh.2020.03.060_bib17","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.cgh.2010.09.019","article-title":"Esophageal eosinophilic infiltration responds to proton pump inhibition in most adults","volume":"9","author":"Molina-Infante","year":"2011","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2020.03.060_bib18","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1053\/j.gastro.2018.10.051","article-title":"RPC4046, a monoclonal antibody against IL13, reduces histologic and endoscopic activity in patients with eosinophilic esophagitis","volume":"156","author":"Hirano","year":"2019","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2020.03.060_bib19","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1053\/j.gastro.2014.02.006","article-title":"Efficacy of dietary interventions for inducing histologic remission in patients with eosinophilic esophagitis: a systematic review and meta-analysis","volume":"146","author":"Arias","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2020.03.060_bib20","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/j.jaci.2011.08.007","article-title":"Subepithelial collagen deposition, profibrogenic cytokine gene expression, and changes after prolonged fluticasone propionate treatment in adult eosinophilic esophagitis: a prospective study","volume":"128","author":"Lucendo","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.cgh.2020.03.060_bib21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.giec.2017.08.001","article-title":"Latest insights on the relationship between symptoms and biologic findings in adults with eosinophilic esophagitis","volume":"28","author":"Safroneeva","year":"2018","journal-title":"Gastrointest Endosc Clin N Am"},{"key":"10.1016\/j.cgh.2020.03.060_bib22","doi-asserted-by":"crossref","first-page":"11019","DOI":"10.3748\/wjg.v20.i31.11019","article-title":"Significance of feeding dysfunction in eosinophilic esophagitis","volume":"20","author":"Menard-Katcher","year":"2014","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cgh.2020.03.060_bib23","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1053\/j.gastro.2014.04.019","article-title":"Efficacy, dose reduction, and resistance to high-dose fluticasone in patients with eosinophilic esophagitis","volume":"147","author":"Butz","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2020.03.060_bib24","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1136\/gutjnl-2014-308815","article-title":"A\u00a0randomised, double-blind trial comparing budesonide formulations and dosages for short-term treatment of eosinophilic oesophagitis","volume":"65","author":"Miehlke","year":"2016","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2020.03.060_bib25","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1097\/MPG.0b013e3181788282","article-title":"14 years of eosinophilic esophagitis: clinical features and prognosis","volume":"48","author":"Spergel","year":"2009","journal-title":"J\u00a0Pediatr Gastroenterol Nutr"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356520304377?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356520304377?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T05:34:33Z","timestamp":1761543273000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356520304377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S1542356520304377"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2020.03.060","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Improvements in Dysphagia and Pain With Swallowing in Patients With Eosinophilic Esophagitis Receiving Budesonide Oral Suspension","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2020.03.060","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 by the AGA Institute. Published by Elsevier, Inc.","name":"copyright","label":"Copyright"}]}}