{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T14:02:49Z","timestamp":1793714569465,"version":"4.6.1"},"reference-count":43,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2022TQ0014"],"award-info":[{"award-number":["2022TQ0014"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2022M720284"],"award-info":[{"award-number":["2022M720284"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cghjournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.cgh.2023.08.013","type":"journal-article","created":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T11:30:19Z","timestamp":1693567819000},"page":"3379-3386.e29","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":150,"title":["Incidence of Inflammatory Bowel Disease in Urban China: A\u00a0Nationwide Population-based Study"],"prefix":"10.1016","volume":"21","author":[{"given":"Lu","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingjie","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yexiang","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liming","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guozhen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyan","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9397-0409","authenticated-orcid":false,"given":"Shengfeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2023.08.013_bib1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1053\/j.gastro.2011.10.001","article-title":"Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review","volume":"142","author":"Molodecky","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2023.08.013_bib2","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/S0140-6736(07)60750-8","article-title":"Inflammatory bowel disease: cause and immunobiology","volume":"369","author":"Baumgart","year":"2007","journal-title":"Lancet"},{"key":"10.1016\/j.cgh.2023.08.013_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S2468-1253(19)30333-4","article-title":"The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990\u20132017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"5","year":"2020","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2023.08.013_bib4","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1016\/S0140-6736(17)32448-0","article-title":"Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies","volume":"390","author":"Ng","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.cgh.2023.08.013_bib5","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1053\/j.gastro.2016.10.020","article-title":"Understanding and preventing the global increase of inflammatory bowel disease","volume":"152","author":"Kaplan","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2023.08.013_bib6","doi-asserted-by":"crossref","first-page":"E17","DOI":"10.1097\/MIB.0000000000000480","article-title":"Increased incidence of inflammatory bowel disease in Korea may not be explained by food additives","volume":"21","author":"Ahn","year":"2015","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2023.08.013_bib7","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.3748\/wjg.v21.i4.1197","article-title":"Inflammatory bowel disease in an underdeveloped region of Northeastern Brazil","volume":"21","author":"Parente","year":"2015","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cgh.2023.08.013_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.eclinm.2020.100544","article-title":"Disease burden of inflammatory bowel disease in China from 1990 to 2017: findings from the global burden of diseases 2017","volume":"27","author":"Qiu","year":"2020","journal-title":"EClinicalMedicine"},{"key":"10.1016\/j.cgh.2023.08.013_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002738","article-title":"Association between temperature variability and daily hospital admissions for cause-specific cardiovascular disease in urban China: a national time-series study","volume":"16","author":"Tian","year":"2019","journal-title":"PLoS Med"},{"key":"10.1016\/j.cgh.2023.08.013_bib10","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-014425","article-title":"Perceived challenges to achieving universal health coverage: a cross-sectional survey of social health insurance managers\/administrators in China","volume":"7","author":"Shan","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.cgh.2023.08.013_bib11","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1377\/hlthaff.2016.1658","article-title":"Health insurance in China: after declining in the 1990s, coverage rates rebounded to near-universal levels by 2011","volume":"36","author":"Li","year":"2017","journal-title":"Health Aff"},{"key":"10.1016\/j.cgh.2023.08.013_bib12","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/ibd.21048","article-title":"World Gastroenterology Organization Practice Guidelines for the diagnosis and management of IBD in 2010","volume":"16","author":"Bernstein","year":"2010","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2023.08.013_bib13","first-page":"26","article-title":"Consensus on the diagnosis and treatment of inflammatory bowel disease (Beijing, 2018)","volume":"38","year":"2018","journal-title":"Chinese Journal of Practical Internal Medicine"},{"key":"10.1016\/j.cgh.2023.08.013_bib14","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/s40264-017-0589-z","article-title":"Evaluation of electronic healthcare databases for post-marketing drug safety surveillance and pharmacoepidemiology in China","volume":"41","author":"Yang","year":"2018","journal-title":"Drug Saf"},{"key":"10.1016\/j.cgh.2023.08.013_bib16","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1093\/ibd\/izz092","article-title":"Comparative incidence of inflammatory bowel disease in different age groups in the United States","volume":"25","author":"Keyashian","year":"2019","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2023.08.013_bib17","series-title":"The clinical evaluation, prognosis follow-up and refractory reason of hospitalized patients with inflammatory bowel disease","author":"Wang","year":"2012"},{"key":"10.1016\/j.cgh.2023.08.013_bib18","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1093\/ecco-jcc\/jjac140","article-title":"Disease activity patterns of inflammatory bowel disease - a Danish nationwide cohort study 1995-2018","volume":"17","author":"Wewer","year":"2023","journal-title":"J\u00a0Crohns Colitis"},{"key":"10.1016\/j.cgh.2023.08.013_bib20","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/s41575-020-00360-x","article-title":"The four epidemiological stages in the global evolution of inflammatory bowel disease","volume":"18","author":"Kaplan","year":"2021","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2023.08.013_bib21","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/s41575-018-0003-z","article-title":"Urbanization and the gut microbiota in health and inflammatory bowel disease","volume":"15","author":"Zuo","year":"2018","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2023.08.013_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.757025","article-title":"Exploring links between industrialization, urbanization, and Chinese inflammatory bowel disease","volume":"8","author":"Cui","year":"2021","journal-title":"Front Med"},{"key":"10.1016\/j.cgh.2023.08.013_bib23","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1080\/13504851.2019.1680791","article-title":"Inflammatory bowel disease and economic activity: panel data evidence for Europe","volume":"27","author":"Michaelides","year":"2019","journal-title":"Applied Economics Letters"},{"key":"10.1016\/j.cgh.2023.08.013_bib24","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/apt.16703","article-title":"Systematic review with meta-analysis: environmental and dietary differences of inflammatory bowel disease in Eastern and Western populations","volume":"55","author":"Zhao","year":"2022","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2023.08.013_bib25","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1002\/ibd.20606","article-title":"What caused the extra high incidence of inflammatory bowel disease in the industrialized countries in the West: lack of some nutrients or increased intake of some harmful agents?","volume":"15","author":"Qin","year":"2009","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2023.08.013_bib26","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1038\/ajg.2017.208","article-title":"Rural and urban\u00a0residence during early life is associated with risk of\u00a0inflammatory bowel disease: a population-based inception and birth cohort study","volume":"112","author":"Benchimol","year":"2017","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2023.08.013_bib27","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.cgh.2016.10.039","article-title":"Incidence and prevalence of Crohn\u2019s disease and ulcerative colitis in Olmsted County, Minnesota from 1970 through 2010","volume":"15","author":"Shivashankar","year":"2017","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2023.08.013_bib28","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1111\/imj.14111","article-title":"Inflammatory bowel disease incidence, prevalence and 12-month initial disease course in Tasmania, Australia","volume":"49","author":"Bhatia","year":"2019","journal-title":"Intern Med J"},{"key":"10.1016\/j.cgh.2023.08.013_bib29","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1097\/MIB.0000000000000162","article-title":"Epidemiology of inflammatory bowel disease in Quebec: recent trends","volume":"20","author":"Bitton","year":"2014","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2023.08.013_bib30","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1038\/s41395-018-0233-2","article-title":"Population density and risk of inflammatory bowel disease: a prospective population-based study in 13 countries or regions in Asia-Pacific","volume":"114","author":"Ng","year":"2019","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2023.08.013_bib31","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1007\/s10620-017-4640-9","article-title":"Incidence and clinical outcomes of inflammatory bowel disease in South Korea, 2011\u20132014: a nationwide population-based study","volume":"62","author":"Jung","year":"2017","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.cgh.2023.08.013_bib32","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.2147\/CLEP.S336517","article-title":"Incidence of inflammatory bowel disease in south Asian and Chinese people: a population-based cohort study from Ontario, Canada","volume":"13","author":"Dhaliwal","year":"2021","journal-title":"Clin Epidemiol"},{"key":"10.1016\/j.cgh.2023.08.013_bib33","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1038\/ajg.2015.52","article-title":"Inflammatory bowel disease in immigrants to Canada and their children: a population-based cohort study","volume":"110","author":"Benchimol","year":"2015","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2023.08.013_bib34","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1159\/000320393","article-title":"Genes and environment: how will our concepts on the pathophysiology of IBD develop in the future?","volume":"28","author":"Kaser","year":"2010","journal-title":"Dig Dis"},{"key":"10.1016\/j.cgh.2023.08.013_bib35","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1046\/j.1365-2036.2003.01607.x","article-title":"NOD2\/CARD15 gene polymorphisms and Crohn's disease in the Chinese population","volume":"17","author":"Leong","year":"2003","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.cgh.2023.08.013_bib36","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1038\/ng.3359","article-title":"Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations","volume":"47","author":"Liu","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.cgh.2023.08.013_bib37","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1136\/gutjnl-2012-303661","article-title":"Epidemiology and Natural History Task Force of the International Organization of Inflammatory Bowel Disease (IOIBD). Geographical variability and environmental risk factors in inflammatory bowel disease","volume":"62","author":"Ng","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2023.08.013_bib1a","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.1016\/S0140-6736(15)00342-6","article-title":"Consolidating the social health insurance schemes in China: towards an equitable and efficient health system","volume":"386","author":"Meng","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.cgh.2023.08.013_bib2a","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1377\/hlthaff.2016.1658","article-title":"Health insurance in China: after declining in the 1990s, coverage rates rebounded to near-universal levels by 2011","volume":"36","author":"Li","year":"2017","journal-title":"Health Aff"},{"key":"10.1016\/j.cgh.2023.08.013_bib3a","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-014425","article-title":"Perceived challenges to achieving universal health coverage: a cross-sectional survey of social health insurance managers\/administrators in China","volume":"7","author":"Shan","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.cgh.2023.08.013_bib4a","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0193273","article-title":"Impact of universal medical insurance system on the accessibility of medical service supply and affordability of patients in China","volume":"13","author":"Xiong","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.cgh.2023.08.013_bib5a","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.jclinepi.2014.02.019","article-title":"Validation of international algorithms to identify adults with inflammatory bowel disease in health administrative data from Ontario, Canada","volume":"67","author":"Benchimol","year":"2014","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.cgh.2023.08.013_bib6a","first-page":"2861","article-title":"Investigation on the prevalence of Crohn's disease among workers insured with urban medical insurance in 24 provinces of China in 2013","volume":"100","author":"Yang","year":"2020","journal-title":"Chinese Medical Journal"},{"key":"10.1016\/j.cgh.2023.08.013_bib7a","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/ibd.21048","article-title":"World Gastroenterology Organization Practice Guidelines for the diagnosis and management of IBD in 2010","volume":"16","author":"Bernstein","year":"2010","journal-title":"Inflamm Bowel Dis"},{"key":"10.1016\/j.cgh.2023.08.013_bib8a","first-page":"26","article-title":"Consensus on the diagnosis and treatment of inflammatory bowel disease (Beijing, 2018)","volume":"38","year":"2018","journal-title":"Chin J Pract Int Med"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356523006626?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356523006626?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T20:29:25Z","timestamp":1778617765000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356523006626"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":43,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S1542356523006626"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2023.08.013","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incidence of Inflammatory Bowel Disease in Urban China: A\u00a0Nationwide Population-based Study","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2023.08.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 by the AGA Institute","name":"copyright","label":"Copyright"}]}}