{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:15:21Z","timestamp":1793646921185,"version":"4.5.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T00:00:00Z","timestamp":1715472000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004095","name":"Kyowa Kirin","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004095","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb Co","doi-asserted-by":"publisher","award":["75267729"],"award-info":[{"award-number":["75267729"]}],"id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","cghjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Gastroenterology and Hepatology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.cgh.2024.04.035","type":"journal-article","created":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T11:32:28Z","timestamp":1715686348000},"page":"2023-2032.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["Epidemiology and Risk Factors of Eosinophilic Esophagitis in Japan: A Population-Based Study"],"prefix":"10.1016","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0590-3693","authenticated-orcid":false,"given":"Akinari","family":"Sawada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Imai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasutaka","family":"Ihara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fumio","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikuo","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Fujiwara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.cgh.2024.04.035_bib1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1053\/j.gastro.2017.06.065","article-title":"Pathophysiology of eosinophilic esophagitis","volume":"154","author":"O\u2019Shea","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2024.04.035_bib2","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1053\/j.gastro.2017.06.067","article-title":"Epidemiology and natural history of eosinophilic esophagitis","volume":"154","author":"Dellon","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2024.04.035_bib3","doi-asserted-by":"crossref","first-page":"3270","DOI":"10.1016\/j.cgh.2023.06.005","article-title":"Global incidence and prevalence of eosinophilic esophagitis, 1976-2022: a systematic review and meta-analysis","volume":"21","author":"Hahn","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2024.04.035_bib4","doi-asserted-by":"crossref","first-page":"3235","DOI":"10.2169\/internalmedicine.51.8670","article-title":"A\u00a0multicenter study on the prevalence of eosinophilic esophagitis and PPI-responsive esophageal eosinophilic infiltration","volume":"51","author":"Fujiwara","year":"2012","journal-title":"Intern Med"},{"key":"10.1016\/j.cgh.2024.04.035_bib5","doi-asserted-by":"crossref","first-page":"8433","DOI":"10.3748\/wjg.v21.i27.8433","article-title":"Systematic review: eosinophilic esophagitis in Asian countries","volume":"21","author":"Kinoshita","year":"2015","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.cgh.2024.04.035_bib6","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jaci.2019.11.013","article-title":"The genetic etiology of eosinophilic esophagitis","volume":"145","author":"Kottyan","year":"2020","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.cgh.2024.04.035_bib7","doi-asserted-by":"crossref","DOI":"10.1093\/dote\/doaa074","article-title":"Early life factors are associated with risk for eosinophilic esophagitis diagnosed in adulthood","volume":"34","author":"Dellon","year":"2021","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.cgh.2024.04.035_bib8","doi-asserted-by":"crossref","first-page":"853","DOI":"10.14309\/ajg.0000000000000597","article-title":"Psychiatric comorbidities and psychiatric medication use are highly prevalent in patients with eosinophilic esophagitis and associate with clinical presentation","volume":"115","author":"Reed","year":"2020","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2024.04.035_bib9","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.jaip.2013.12.003","article-title":"Alcohol-induced respiratory symptoms are common in patients with aspirin exacerbated respiratory disease","volume":"2","author":"Cardet","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"key":"10.1016\/j.cgh.2024.04.035_bib10","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1111\/jdv.15642","article-title":"Atopic dermatitis and the metabolic syndrome: a cross-sectional study of 116 816 patients","volume":"33","author":"Shalom","year":"2019","journal-title":"J\u00a0Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.cgh.2024.04.035_bib11","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1111\/ced.15212","article-title":"Association between moderate to severe atopic dermatitis and lifestyle factors in the Dutch general population","volume":"47","author":"Zhang","year":"2022","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.cgh.2024.04.035_bib12","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.jaad.2016.07.017","article-title":"Association of atopic dermatitis with smoking: a systematic review and meta-analysis","volume":"75","author":"Kantor","year":"2016","journal-title":"J\u00a0Am Acad Dermatol"},{"key":"10.1016\/j.cgh.2024.04.035_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/dote\/dox111","article-title":"Impact of smoking, alcohol consumption, and NSAID use on risk for and phenotypes of eosinophilic esophagitis","volume":"31","author":"Koutlas","year":"2018","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.cgh.2024.04.035_bib14","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s10388-019-00662-3","article-title":"Obesity and hiatal hernia may be non-allergic risk factors for esophageal eosinophilia in Japanese adults","volume":"16","author":"Tanaka","year":"2019","journal-title":"Esophagus"},{"key":"10.1016\/j.cgh.2024.04.035_bib15","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1007\/s10388-021-00838-w","article-title":"Obesity reduces the requirement for subsequent esophageal stricture dilation in adults with eosinophilic esophagitis","volume":"18","author":"Miller","year":"2021","journal-title":"Esophagus"},{"key":"10.1016\/j.cgh.2024.04.035_bib16","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1016\/j.cgh.2022.11.004","article-title":"Higher body mass index is associated with decreased treatment response to topical steroids in eosinophilic esophagitis","volume":"21","author":"Ketchem","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2024.04.035_bib17","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.cgh.2015.08.034","article-title":"Effects of race and sex on features of eosinophilic esophagitis","volume":"14","author":"Moawad","year":"2016","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2024.04.035_bib18","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1007\/s00535-012-0640-x","article-title":"Clinical characteristics of Japanese patients with eosinophilic esophagitis and eosinophilic gastroenteritis","volume":"48","author":"Kinoshita","year":"2013","journal-title":"J\u00a0Gastroenterol"},{"key":"10.1016\/j.cgh.2024.04.035_bib19","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1016\/j.jaci.2018.10.070","article-title":"17beta-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling","volume":"143","author":"Wheeler","year":"2019","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.cgh.2024.04.035_bib20","first-page":"118","article-title":"Data resource profile: JMDC claims database sourced from health insurance societies","volume":"22","author":"Nagai","year":"2021","journal-title":"J\u00a0Gen Fam Med"},{"key":"10.1016\/j.cgh.2024.04.035_bib21","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1007\/s00535-018-1483-x","article-title":"A\u00a0case-control study of the risk of upper gastrointestinal mucosal injuries in patients prescribed concurrent NSAIDs and antithrombotic drugs based on data from the Japanese national claims database of 13 million accumulated patients","volume":"53","author":"Sugisaki","year":"2018","journal-title":"J\u00a0Gastroenterol"},{"key":"10.1016\/j.cgh.2024.04.035_bib22","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1093\/ije\/dys147","article-title":"Case-control studies: basic concepts","volume":"41","author":"Vandenbroucke","year":"2012","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.cgh.2024.04.035_bib23","doi-asserted-by":"crossref","first-page":"3030","DOI":"10.1016\/j.cgh.2023.03.033","article-title":"Development and validation of the Veterans Affairs Eosinophilic Esophagitis Cohort","volume":"21","author":"Low","year":"2023","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2024.04.035_bib24","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.cgh.2013.09.008","article-title":"Prevalence of eosinophilic esophagitis in the United States","volume":"12","author":"Dellon","year":"2014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2024.04.035_bib25","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.jaci.2013.02.030","article-title":"High prevalence of eosinophilic esophagitis in patients with inherited connective tissue disorders","volume":"132","author":"Abonia","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"key":"10.1016\/j.cgh.2024.04.035_bib26","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1038\/ajg.2016.185","article-title":"Risk of autoimmunity in EoE and families: a population-based cohort study","volume":"111","author":"Peterson","year":"2016","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.cgh.2024.04.035_bib27","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1053\/j.gastro.2018.07.009","article-title":"Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: proceedings of the AGREE Conference","volume":"155","author":"Dellon","year":"2018","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2024.04.035_bib28","doi-asserted-by":"crossref","DOI":"10.3402\/ecrj.v2.24642","article-title":"Epidemiology and natural history of atopic diseases","volume":"2","author":"Thomsen","year":"2015","journal-title":"Eur Clin Respir J"},{"key":"10.1016\/j.cgh.2024.04.035_bib29","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.alit.2020.04.001","article-title":"Japanese guidelines for allergic rhinitis 2020","volume":"69","author":"Okubo","year":"2020","journal-title":"Allergol Int"},{"key":"10.1016\/j.cgh.2024.04.035_bib30","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.alit.2020.08.001","article-title":"Japanese guidelines for adult asthma 2020","volume":"69","author":"Nakamura","year":"2020","journal-title":"Allergol Int"},{"key":"10.1016\/j.cgh.2024.04.035_bib31","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1053\/j.gastro.2011.06.081","article-title":"Inverse association of esophageal eosinophilia with Helicobacter pylori based on analysis of a US pathology database","volume":"141","author":"Dellon","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.cgh.2024.04.035_bib32","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.jdermsci.2009.04.004","article-title":"Prevalence of atopic dermatitis in Japanese adults and community validation of the U.K. diagnostic criteria","volume":"55","author":"Saeki","year":"2009","journal-title":"J\u00a0Dermatol Sci"},{"key":"10.1016\/j.cgh.2024.04.035_bib33","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1111\/pcn.12894","article-title":"Prevalence of mental disorders and mental health service use in Japan","volume":"73","author":"Nishi","year":"2019","journal-title":"Psychiatry Clin Neurosci"},{"key":"10.1016\/j.cgh.2024.04.035_bib34","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.sleep.2016.05.013","article-title":"Nationwide epidemiological study of insomnia in Japan","volume":"25","author":"Itani","year":"2016","journal-title":"Sleep Med"},{"key":"10.1016\/j.cgh.2024.04.035_bib35","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1440-1746.2008.05634.x","article-title":"The additive effect of ethanol and extract of cigarette smoke on rabbit esophagus epithelium","volume":"24","author":"Bor","year":"2009","journal-title":"J\u00a0Gastroenterol Hepatol"},{"key":"10.1016\/j.cgh.2024.04.035_bib36","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1136\/gutjnl-2018-318074","article-title":"Epidemiology and implications of concurrent diagnosis of eosinophilic oesophagitis and IBD based on a prospective population-based analysis","volume":"68","author":"Limketkai","year":"2019","journal-title":"Gut"},{"key":"10.1016\/j.cgh.2024.04.035_bib37","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.4065\/81.11.1462","article-title":"Smoking and inflammatory bowel disease: a meta-analysis","volume":"81","author":"Mahid","year":"2006","journal-title":"Mayo Clin Proc"}],"container-title":["Clinical Gastroenterology and Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356524004476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1542356524004476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T20:53:29Z","timestamp":1727124809000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1542356524004476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["S1542356524004476"],"URL":"https:\/\/doi.org\/10.1016\/j.cgh.2024.04.035","relation":{},"ISSN":["1542-3565"],"issn-type":[{"value":"1542-3565","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epidemiology and Risk Factors of Eosinophilic Esophagitis in Japan: A Population-Based Study","name":"articletitle","label":"Article Title"},{"value":"Clinical Gastroenterology and Hepatology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.cgh.2024.04.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}