{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T10:09:14Z","timestamp":1792145354608,"version":"4.4.0"},"reference-count":101,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH103436"],"award-info":[{"award-number":["MH103436"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","award":["MH096777"],"award-info":[{"award-number":["MH096777"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","theclinics.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Child and Adolescent Psychiatric Clinics of North America"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.chc.2019.05.007","type":"journal-article","created":{"date-parts":[[2019,7,4]],"date-time":"2019-07-04T10:09:29Z","timestamp":1562234969000},"page":"629-640","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":133,"title":["The Neurobiology of Eating Disorders"],"prefix":"10.1016","volume":"28","author":[{"given":"Guido K.W.","family":"Frank","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan E.","family":"Shott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa C.","family":"DeGuzman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chc.2019.05.007_bib1","series-title":"Desk reference to the diagnostic criteria from DSM-5","author":"American Psychiatric Association","year":"2013"},{"issue":"4 Suppl","key":"10.1016\/j.chc.2019.05.007_bib2","doi-asserted-by":"crossref","first-page":"A29","DOI":"10.1227\/01.NEU.0000351279.78110.00","article-title":"Magnetic resonance neurography and diffusion tensor imaging: origins, history, and clinical impact of the first 50,000 cases with an assessment of efficacy and utility in a prospective 5000-patient study group","volume":"65","author":"Filler","year":"2009","journal-title":"Neurosurgery"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib3","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1073\/pnas.95.3.765","article-title":"Behind the scenes of functional brain imaging: a historical and physiological perspective","volume":"95","author":"Raichle","year":"1998","journal-title":"Proc Natl Acad Sci U\u00a0S\u00a0A"},{"issue":"4","key":"10.1016\/j.chc.2019.05.007_bib4","first-page":"451","article-title":"Towards trans-diagnostic mechanisms in psychiatry: neurobehavioral profile of rats with a loss-of-function point mutation in the dopamine transporter gene","volume":"10","author":"Vengeliene","year":"2017","journal-title":"Dis Model Mech"},{"issue":"14","key":"10.1016\/j.chc.2019.05.007_bib5","doi-asserted-by":"crossref","first-page":"3586","DOI":"10.1523\/JNEUROSCI.5309-07.2008","article-title":"Neurodevelopmental trajectories of the human cerebral cortex","volume":"28","author":"Shaw","year":"2008","journal-title":"J\u00a0Neurosci"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib6","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/nrn.2016.167","article-title":"Scanning the horizon: towards transparent and reproducible neuroimaging research","volume":"18","author":"Poldrack","year":"2017","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.chc.2019.05.007_bib7","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1017\/S1092852915000012","article-title":"Advances from neuroimaging studies in eating disorders","volume":"20","author":"Frank","year":"2015","journal-title":"CNS Spectr"},{"key":"10.1016\/j.chc.2019.05.007_bib8","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3389\/fnbeh.2016.00044","article-title":"The perfect storm - a bio-psycho-social risk model for developing and maintaining eating disorders","volume":"10","author":"Frank","year":"2016","journal-title":"Front Behav Neurosci"},{"issue":"5","key":"10.1016\/j.chc.2019.05.007_bib9","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1002\/eat.20984","article-title":"Striatal dopamine in bulimia nervosa: a PET imaging study","volume":"45","author":"Broft","year":"2012","journal-title":"Int J Eat Disord"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib10","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.psyneuen.2012.10.021","article-title":"Dysfunctions of leptin, ghrelin, BDNF and endocannabinoids in eating disorders: beyond the homeostatic control of food intake","volume":"38","author":"Monteleone","year":"2013","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.chc.2019.05.007_bib11","article-title":"Neuroendocrinology of reward in anorexia nervosa and bulimia nervosa: beyond leptin and ghrelin","author":"Berner","year":"2018","journal-title":"Mol Cell Endocrinol"},{"issue":"Pt B","key":"10.1016\/j.chc.2019.05.007_bib12","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.pnpbp.2017.02.020","article-title":"Neuroendocrinology and brain imaging of reward in eating disorders: a possible key to the treatment of anorexia nervosa and bulimia nervosa","volume":"80","author":"Monteleone","year":"2018","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.chc.2019.05.007_bib13","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.psyneuen.2014.09.031","article-title":"Inflammatory cytokines and anorexia nervosa: a meta-analysis of cross-sectional and longitudinal studies","volume":"51","author":"Solmi","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.chc.2019.05.007_bib14","article-title":"A\u00a0systematic review of in\u00a0vitro cytokine production in eating disorders","author":"Dalton","year":"2018","journal-title":"Mol Cell Endocrinol"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib15","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1002\/erv.1163","article-title":"Structural magnetic resonance imaging in eating disorders: a systematic review of voxel-based morphometry studies","volume":"20","author":"Van den Eynde","year":"2012","journal-title":"Eur Eat Disord Rev"},{"key":"10.1016\/j.chc.2019.05.007_bib16","first-page":"3","article-title":"Neuroimaging in bulimia nervosa and binge eating disorder: a systematic review","volume":"6","author":"Donnelly","year":"2018","journal-title":"J\u00a0Eat Disord"},{"issue":"7","key":"10.1016\/j.chc.2019.05.007_bib17","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.biopsych.2015.01.012","article-title":"What causes eating disorders, and what do they cause?","volume":"77","author":"Frank","year":"2015","journal-title":"Biol Psychiatry"},{"issue":"7","key":"10.1016\/j.chc.2019.05.007_bib18","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.biopsych.2014.09.005","article-title":"Global cortical thinning in acute anorexia nervosa normalizes following long-term weight restoration","volume":"77","author":"King","year":"2015","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.chc.2019.05.007_bib19","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.neuroimage.2016.02.003","article-title":"Weight restoration therapy rapidly reverses cortical thinning in anorexia nervosa: a longitudinal study","volume":"130","author":"Bernardoni","year":"2016","journal-title":"Neuroimage"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib20","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1080\/08039488.2016.1250948","article-title":"Adolescents newly diagnosed with eating disorders have structural differences in brain regions linked with eating disorder symptoms","volume":"71","author":"Solstrand Dahlberg","year":"2017","journal-title":"Nord J Psychiatry"},{"issue":"7","key":"10.1016\/j.chc.2019.05.007_bib21","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1111\/ejn.13659","article-title":"Grey matter volume in adolescents with anorexia nervosa and associated eating disorder symptoms","volume":"46","author":"Martin Monzon","year":"2017","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.chc.2019.05.007_bib22","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.pscychresns.2017.07.004","article-title":"Regional decrease in gray matter volume is related to body dissatisfaction in anorexia nervosa","volume":"267","author":"Kohmura","year":"2017","journal-title":"Psychiatry Res Neuroimaging"},{"issue":"9","key":"10.1016\/j.chc.2019.05.007_bib23","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1002\/eat.22918","article-title":"Recovery of cortical volume and thickness after remission from acute anorexia nervosa","volume":"51","author":"Nickel","year":"2018","journal-title":"Int J Eat Disord"},{"issue":"10","key":"10.1016\/j.chc.2019.05.007_bib24","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/j.jaac.2013.07.007","article-title":"Localized brain volume and white matter integrity alterations in adolescent anorexia nervosa","volume":"52","author":"Frank","year":"2013","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"issue":"10","key":"10.1016\/j.chc.2019.05.007_bib25","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1176\/appi.ajp.2013.12101294","article-title":"Alterations in brain structures related to taste reward circuitry in ill and recovered anorexia nervosa and in bulimia nervosa","volume":"170","author":"Frank","year":"2013","journal-title":"Am J Psychiatry"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib26","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.pscychresns.2013.03.010","article-title":"Brain volumetric abnormalities in patients with anorexia and bulimia nervosa: a voxel-based morphometry study","volume":"213","author":"Amianto","year":"2013","journal-title":"Psychiatry Res"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib27","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.pscychresns.2010.02.004","article-title":"Voxel-based morphometry in eating disorders: correlation of psychopathology with grey matter volume","volume":"182","author":"Joos","year":"2010","journal-title":"Psychiatry Res"},{"issue":"7","key":"10.1016\/j.chc.2019.05.007_bib28","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.biopsych.2013.07.017","article-title":"Anatomical characteristics of the cerebral surface in bulimia nervosa","volume":"77","author":"Marsh","year":"2015","journal-title":"Biol Psychiatry"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib29","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1503\/jpn.170070","article-title":"Altered cortical thickness and attentional deficits in adolescent girls and women with bulimia nervosa","volume":"43","author":"Berner","year":"2018","journal-title":"J\u00a0Psychiatry Neurosci"},{"key":"10.1016\/j.chc.2019.05.007_bib30","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.pscychresns.2017.11.006","article-title":"Associations between cortical thickness, structural connectivity and severity of dimensional bulimia nervosa symptomatology","volume":"271","author":"Westwater","year":"2018","journal-title":"Psychiatry Res Neuroimaging"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib31","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.biopsych.2017.08.011","article-title":"Structural neuroimaging of anorexia nervosa: future directions in the quest for mechanisms underlying dynamic alterations","volume":"83","author":"King","year":"2018","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.chc.2019.05.007_bib32","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3389\/fnhum.2016.00271","article-title":"Understanding neuronal architecture in obesity through analysis of white matter connection strength","volume":"10","author":"Riederer","year":"2016","journal-title":"Front Hum Neurosci"},{"issue":"8","key":"10.1016\/j.chc.2019.05.007_bib33","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1002\/eat.22161","article-title":"Normal gray and white matter volume after weight restoration in adolescents with anorexia nervosa","volume":"46","author":"Lazaro","year":"2013","journal-title":"Int J Eat Disord"},{"issue":"8","key":"10.1016\/j.chc.2019.05.007_bib34","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1007\/s00702-016-1567-9","article-title":"Brain morphological changes in adolescent and adult patients with anorexia nervosa","volume":"123","author":"Seitz","year":"2016","journal-title":"J\u00a0Neural Transm (Vienna)"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib35","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1080\/15622975.2016.1273552","article-title":"Reduced astrocyte density underlying brain volume reduction in activity-based anorexia rats","volume":"19","author":"Frintrop","year":"2018","journal-title":"World J Biol Psychiatry"},{"key":"10.1016\/j.chc.2019.05.007_bib36","doi-asserted-by":"crossref","first-page":"S163","DOI":"10.1102\/1470-7330.2010.9023","article-title":"Diffusion-weighted and diffusion tensor imaging of the brain, made easy","volume":"10 Spec no A","author":"Huisman","year":"2010","journal-title":"Cancer Imaging"},{"issue":"11","key":"10.1016\/j.chc.2019.05.007_bib37","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.1002\/hbm.23279","article-title":"Abnormal reward circuitry in anorexia nervosa: a longitudinal, multimodal MRI study","volume":"37","author":"Cha","year":"2016","journal-title":"Hum Brain Mapp"},{"issue":"11","key":"10.1016\/j.chc.2019.05.007_bib38","doi-asserted-by":"crossref","first-page":"4069","DOI":"10.1002\/hbm.23296","article-title":"Preserved white matter microstructure in young patients with anorexia nervosa?","volume":"37","author":"Pfuhl","year":"2016","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.chc.2019.05.007_bib39","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.nicl.2015.10.008","article-title":"Abnormal white matter properties in adolescent girls with anorexia nervosa","volume":"9","author":"Travis","year":"2015","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.chc.2019.05.007_bib40","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.nicl.2016.04.002","article-title":"White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study","volume":"11","author":"Vogel","year":"2016","journal-title":"Neuroimage Clin"},{"issue":"11","key":"10.1016\/j.chc.2019.05.007_bib41","doi-asserted-by":"crossref","first-page":"4385","DOI":"10.1002\/hbm.24279","article-title":"White matter microstructure in anorexia nervosa","volume":"39","author":"Phillipou","year":"2018","journal-title":"Hum Brain Mapp"},{"issue":"9","key":"10.1016\/j.chc.2019.05.007_bib42","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1017\/S003329171800212X","article-title":"Dynamic changes in white matter microstructure in anorexia nervosa: findings from a longitudinal study","volume":"49","author":"von Schwanenflug","year":"2019","journal-title":"Psychol Med"},{"issue":"11","key":"10.1016\/j.chc.2019.05.007_bib43","doi-asserted-by":"crossref","first-page":"e932","DOI":"10.1038\/tp.2016.199","article-title":"Altered structural and effective connectivity in anorexia and bulimia nervosa in circuits that regulate energy and reward homeostasis","volume":"6","author":"Frank","year":"2016","journal-title":"Transl Psychiatry"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib44","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1002\/eat.22083","article-title":"White matter integrity is reduced in bulimia nervosa","volume":"46","author":"Mettler","year":"2013","journal-title":"Int J Eat Disord"},{"issue":"7","key":"10.1016\/j.chc.2019.05.007_bib45","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1038\/npp.2015.354","article-title":"Altered white matter microstructure in adolescents and adults with bulimia nervosa","volume":"41","author":"He","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib46","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/npp.2015.172","article-title":"Greater insula white matter fiber connectivity in women recovered from anorexia nervosa","volume":"41","author":"Shott","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib47","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/hbm.22202","article-title":"Increased resting state functional connectivity in the default mode network in recovered anorexia nervosa","volume":"35","author":"Cowdrey","year":"2014","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.chc.2019.05.007_bib48","doi-asserted-by":"crossref","first-page":"346","DOI":"10.3389\/fnbeh.2014.00346","article-title":"Increased resting state functional connectivity in the fronto-parietal and default mode network in anorexia nervosa","volume":"8","author":"Boehm","year":"2014","journal-title":"Front Behav Neurosci"},{"issue":"6","key":"10.1016\/j.chc.2019.05.007_bib49","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1503\/jpn.150259","article-title":"Partially restored resting-state functional connectivity in women recovered from anorexia nervosa","volume":"41","author":"Boehm","year":"2016","journal-title":"J\u00a0Psychiatry Neurosci"},{"issue":"1","key":"10.1016\/j.chc.2019.05.007_bib50","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s12868-018-0433-0","article-title":"Altered functional connectivity of the default mode network by glucose loading in young, healthy participants","volume":"19","author":"Ishibashi","year":"2018","journal-title":"BMC Neurosci"},{"issue":"9","key":"10.1016\/j.chc.2019.05.007_bib51","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1523\/JNEUROSCI.5587-06.2007","article-title":"Dissociable intrinsic connectivity networks for salience processing and executive control","volume":"27","author":"Seeley","year":"2007","journal-title":"J\u00a0Neurosci"},{"issue":"1","key":"10.1016\/j.chc.2019.05.007_bib52","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.pscychresns.2013.11.004","article-title":"Resting-state synchrony between anterior cingulate cortex and precuneus relates to body shape concern in anorexia nervosa and bulimia nervosa","volume":"221","author":"Lee","year":"2014","journal-title":"Psychiatry Res"},{"issue":"6","key":"10.1016\/j.chc.2019.05.007_bib53","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.1038\/npp.2015.314","article-title":"Evidence for thalamocortical circuit abnormalities and associated cognitive dysfunctions in underweight individuals with anorexia nervosa","volume":"41","author":"Biezonski","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib54","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.neulet.2012.05.075","article-title":"Functional and effective connectivity of anterior insula in anorexia nervosa and bulimia nervosa","volume":"521","author":"Kim","year":"2012","journal-title":"Neurosci Lett"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib55","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1503\/jpn.130046","article-title":"Reduced salience and default mode network activity in women with anorexia nervosa","volume":"39","author":"McFadden","year":"2014","journal-title":"J\u00a0Psychiatry Neurosci"},{"key":"10.1016\/j.chc.2019.05.007_bib56","doi-asserted-by":"crossref","first-page":"10818","DOI":"10.1038\/srep10818","article-title":"Altered resting-state functional connectivity of anterior cingulate cortex in drug-naive adolescents at the earliest stages of anorexia nervosa","volume":"5","author":"Gaudio","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.chc.2019.05.007_bib57","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.nicl.2014.04.002","article-title":"Aberrant network integrity of the inferior frontal cortex in women with anorexia nervosa","volume":"4","author":"Kullmann","year":"2014","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.chc.2019.05.007_bib58","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1146\/annurev-neuro-071013-014030","article-title":"The brain's default mode network","volume":"38","author":"Raichle","year":"2015","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.chc.2019.05.007_bib59","doi-asserted-by":"crossref","first-page":"295","DOI":"10.3389\/fpsyg.2012.00295","article-title":"Resting state networks and consciousness: alterations of multiple resting state network connectivity in physiological, pharmacological, and pathological consciousness States","volume":"3","author":"Heine","year":"2012","journal-title":"Front Psychol"},{"issue":"10","key":"10.1016\/j.chc.2019.05.007_bib60","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1001\/jamapsychiatry.2018.2151","article-title":"Association of brain reward learning response with harm avoidance, weight gain, and hypothalamic effective connectivity in adolescent anorexia nervosa","volume":"75","author":"Frank","year":"2018","journal-title":"JAMA Psychiatry"},{"issue":"9","key":"10.1016\/j.chc.2019.05.007_bib61","doi-asserted-by":"crossref","first-page":"3306","DOI":"10.1523\/JNEUROSCI.22-09-03306.2002","article-title":"The neuroscience of natural rewards: relevance to addictive drugs","volume":"22","author":"Kelley","year":"2002","journal-title":"J\u00a0Neurosci"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib62","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1176\/appi.ajp.2009.09010071","article-title":"A\u00a0neural signature of anorexia nervosa in the ventral striatal reward system","volume":"167","author":"Fladung","year":"2010","journal-title":"Am J Psychiatry"},{"issue":"5","key":"10.1016\/j.chc.2019.05.007_bib63","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1503\/jpn.110156","article-title":"Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa","volume":"37","author":"Holsen","year":"2012","journal-title":"J\u00a0Psychiatry Neurosci"},{"key":"10.1016\/j.chc.2019.05.007_bib64","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3389\/fnbeh.2015.00046","article-title":"Altered food-cue processing in chronically ill and recovered women with anorexia nervosa","volume":"9","author":"Sanders","year":"2015","journal-title":"Front Behav Neurosci"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib65","doi-asserted-by":"crossref","first-page":"e0191059","DOI":"10.1371\/journal.pone.0191059","article-title":"Neural processing of food and emotional stimuli in adolescent and adult anorexia nervosa patients","volume":"13","author":"Horndasch","year":"2018","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.chc.2019.05.007_bib66","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1017\/S0033291717002161","article-title":"Subliminal and supraliminal processing of reward-related stimuli in anorexia nervosa","volume":"48","author":"Boehm","year":"2018","journal-title":"Psychol Med"},{"issue":"1","key":"10.1016\/j.chc.2019.05.007_bib67","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41398-017-0004-7","article-title":"The real-life costs of emotion regulation in anorexia nervosa: a combined ecological momentary assessment and fMRI study","volume":"8","author":"Seidel","year":"2018","journal-title":"Transl Psychiatry"},{"issue":"11","key":"10.1016\/j.chc.2019.05.007_bib68","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.jaac.2016.08.005","article-title":"Altered neural efficiency of decision making during temporal reward discounting in anorexia nervosa","volume":"55","author":"King","year":"2016","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib69","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.pscychresns.2013.07.004","article-title":"Altered brain response to reward and punishment in adolescents with anorexia nervosa","volume":"214","author":"Bischoff-Grethe","year":"2013","journal-title":"Psychiatry Res Neuroimaging"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib70","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.biopsych.2017.07.024","article-title":"Altered medial frontal feedback learning signals in anorexia nervosa","volume":"83","author":"Bernardoni","year":"2018","journal-title":"Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.chc.2019.05.007_bib71","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1002\/eat.22709","article-title":"Decreased feedback learning in anorexia nervosa persists after weight restoration","volume":"50","author":"Foerde","year":"2017","journal-title":"Int J Eat Disord"},{"issue":"8","key":"10.1016\/j.chc.2019.05.007_bib72","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.biopsych.2011.05.028","article-title":"Increased neural processing of rewarding and aversive food stimuli in recovered anorexia nervosa","volume":"70","author":"Cowdrey","year":"2011","journal-title":"Biol Psychiatry"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib73","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0896-6273(02)00967-4","article-title":"Getting formal with dopamine and reward","volume":"36","author":"Schultz","year":"2002","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib74","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/S0896-6273(03)00169-7","article-title":"Temporal difference models and reward-related learning in the human brain","volume":"38","author":"O'Doherty","year":"2003","journal-title":"Neuron"},{"issue":"6","key":"10.1016\/j.chc.2019.05.007_bib75","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1176\/appi.ajp.2016.16060671","article-title":"Association of elevated reward prediction error response with weight gain in adolescent anorexia nervosa","volume":"174","author":"DeGuzman","year":"2017","journal-title":"Am J Psychiatry"},{"issue":"4","key":"10.1016\/j.chc.2019.05.007_bib76","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/eat.22704","article-title":"The partial dopamine D2 receptor agonist aripiprazole is associated with weight gain in adolescent anorexia nervosa","volume":"50","author":"Frank","year":"2017","journal-title":"Int J Eat Disord"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib77","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/j.appet.2012.02.051","article-title":"Negative affect and neural response to palatable food intake in bulimia nervosa","volume":"58","author":"Bohon","year":"2012","journal-title":"Appetite"},{"issue":"11","key":"10.1016\/j.chc.2019.05.007_bib78","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.jaac.2016.07.778","article-title":"Reward-based spatial learning in teens with bulimia nervosa","volume":"55","author":"Cyr","year":"2016","journal-title":"J\u00a0Am Acad Child Adolesc Psychiatry"},{"issue":"10","key":"10.1016\/j.chc.2019.05.007_bib79","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1007\/s11920-013-0396-x","article-title":"Altered brain reward circuits in eating disorders: chicken or egg?","volume":"15","author":"Frank","year":"2013","journal-title":"Curr Psychiatry Rep"},{"key":"10.1016\/j.chc.2019.05.007_bib80","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.3389\/fpsyg.2015.01181","article-title":"Self perception and facial emotion perception of others in anorexia nervosa","volume":"6","author":"Phillipou","year":"2015","journal-title":"Front Psychol"},{"key":"10.1016\/j.chc.2019.05.007_bib81","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.nicl.2013.12.002","article-title":"Increased BOLD signal in the fusiform gyrus during implicit emotion processing in anorexia nervosa","volume":"4","author":"Fonville","year":"2014","journal-title":"Neuroimage Clin"},{"issue":"2","key":"10.1016\/j.chc.2019.05.007_bib82","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1038\/npp.2015.174","article-title":"Altered insula activity during visceral interoception in weight-restored patients with anorexia nervosa","volume":"41","author":"Kerr","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"6","key":"10.1016\/j.chc.2019.05.007_bib83","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1002\/eat.22538","article-title":"Extremes of eating are associated with reduced neural taste discrimination","volume":"49","author":"Frank","year":"2016","journal-title":"Int J Eat Disord"},{"key":"10.1016\/j.chc.2019.05.007_bib84","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.neulet.2017.04.054","article-title":"Impaired prefrontal cognitive control over interference by food images in binge-eating disorder and bulimia nervosa","volume":"651","author":"Lee","year":"2017","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.chc.2019.05.007_bib85","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3389\/fpsyt.2017.00172","article-title":"Increased subjective distaste and altered insula activity to umami tastant in patients with bulimia nervosa","volume":"8","author":"Setsu","year":"2017","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.chc.2019.05.007_bib86","doi-asserted-by":"crossref","first-page":"42066","DOI":"10.1038\/srep42066","article-title":"Increased anterior cingulate cortex response precedes behavioural adaptation in anorexia nervosa","volume":"7","author":"Geisler","year":"2017","journal-title":"Sci Rep"},{"issue":"5","key":"10.1016\/j.chc.2019.05.007_bib87","doi-asserted-by":"crossref","first-page":"e0124027","DOI":"10.1371\/journal.pone.0124027","article-title":"Aberrant function of learning and cognitive control networks underlie inefficient cognitive flexibility in anorexia nervosa: a cross-sectional fMRI study","volume":"10","author":"Lao-Kaim","year":"2015","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.chc.2019.05.007_bib88","doi-asserted-by":"crossref","first-page":"e0161329","DOI":"10.1371\/journal.pone.0161329","article-title":"Attention network dysfunction in bulimia nervosa - an fMRI study","volume":"11","author":"Seitz","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.chc.2019.05.007_bib89","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.pscychresns.2017.05.001","article-title":"Patients with bulimia nervosa do not show typical neurodevelopment of cognitive control under emotional influences","volume":"266","author":"Dreyfuss","year":"2017","journal-title":"Psychiatry Res Neuroimaging"},{"key":"10.1016\/j.chc.2019.05.007_bib90","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpsychires.2016.12.005","article-title":"Neural activations are related to body-shape, anxiety, and outcomes in adolescent anorexia nervosa","volume":"87","author":"Xu","year":"2017","journal-title":"J\u00a0Psychiatr Res"},{"key":"10.1016\/j.chc.2019.05.007_bib91","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.pscychresns.2018.08.007","article-title":"Abnormal brain processing of gentle touch in anorexia nervosa","volume":"281","author":"Davidovic","year":"2018","journal-title":"Psychiatry Res Neuroimaging"},{"key":"10.1016\/j.chc.2019.05.007_bib92","article-title":"Intimate stimuli result in fronto-parietal activation changes in anorexia nervosa","author":"van Zutphen","year":"2018","journal-title":"Eat Weight Disord"},{"issue":"Suppl 1","key":"10.1016\/j.chc.2019.05.007_bib93","doi-asserted-by":"crossref","first-page":"S38","DOI":"10.1111\/j.1753-4887.2012.00493.x","article-title":"Defining the human microbiome","volume":"70","author":"Ursell","year":"2012","journal-title":"Nutr Rev"},{"issue":"7164","key":"10.1016\/j.chc.2019.05.007_bib94","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1038\/nature06244","article-title":"The human microbiome project","volume":"449","author":"Turnbaugh","year":"2007","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.chc.2019.05.007_bib95","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/nyas.13969","article-title":"The gut-brain axis in health neuroscience: implications for functional gastrointestinal disorders and appetite regulation","volume":"1428","author":"Weltens","year":"2018","journal-title":"Ann N Y Acad Sci"},{"issue":"6","key":"10.1016\/j.chc.2019.05.007_bib96","doi-asserted-by":"crossref","first-page":"e0179739","DOI":"10.1371\/journal.pone.0179739","article-title":"Microbiota in anorexia nervosa: the triangle between bacterial species, metabolites and psychological tests","volume":"12","author":"Borgo","year":"2017","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.chc.2019.05.007_bib97","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1007\/s40519-018-0499-9","article-title":"A\u00a0systematic review of studies on the faecal microbiota in anorexia nervosa: future research may need to include microbiota from the small intestine","volume":"23","author":"Schwensen","year":"2018","journal-title":"Eat Weight Disord"},{"issue":"9","key":"10.1016\/j.chc.2019.05.007_bib98","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1097\/PSY.0000000000000247","article-title":"The intestinal microbiota in acute anorexia nervosa and during renourishment: relationship to depression, anxiety, and eating disorder psychopathology","volume":"77","author":"Kleiman","year":"2015","journal-title":"Psychosom Med"},{"issue":"12","key":"10.1016\/j.chc.2019.05.007_bib99","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1002\/eat.22801","article-title":"Gut microbiota and body composition in anorexia nervosa inpatients in comparison to athletes, overweight, obese, and normal weight controls","volume":"50","author":"Morkl","year":"2017","journal-title":"Int J Eat Disord"},{"issue":"8","key":"10.1016\/j.chc.2019.05.007_bib100","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.2174\/1570159X16666180118101354","article-title":"Is the impact of starvation on the gut microbiota specific or unspecific to anorexia nervosa? A narrative review based on a systematic literature search","volume":"16","author":"Mack","year":"2018","journal-title":"Curr Neuropharmacol"},{"issue":"3","key":"10.1016\/j.chc.2019.05.007_bib101","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/eat.22829","article-title":"Toward valid and reliable brain imaging results in eating disorders","volume":"51","author":"Frank","year":"2018","journal-title":"Int J Eat Disord"}],"container-title":["Child and Adolescent Psychiatric Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056499319300598?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1056499319300598?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T22:16:27Z","timestamp":1778796987000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1056499319300598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":101,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S1056499319300598"],"URL":"https:\/\/doi.org\/10.1016\/j.chc.2019.05.007","relation":{},"ISSN":["1056-4993"],"issn-type":[{"value":"1056-4993","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Neurobiology of Eating Disorders","name":"articletitle","label":"Article Title"},{"value":"Child and Adolescent Psychiatric Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chc.2019.05.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}