{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:40:30Z","timestamp":1789706430741,"version":"4.0.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,3,21]],"date-time":"2014-03-21T00:00:00Z","timestamp":1395360000000},"content-version":"vor","delay-in-days":385,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemistry & Biology"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.chembiol.2012.12.009","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T13:25:53Z","timestamp":1363872353000},"page":"351-359","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"title":["Discovery of Peptoid Ligands for Anti-Aquaporin 4 Antibodies"],"prefix":"10.1016","volume":"20","author":[{"given":"Bindu\u00a0L.","family":"Raveendra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Baccala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.\u00a0Muralidhar","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Schilke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey\u00a0L.","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Argyrios\u00a0N.","family":"Theofilopoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Kodadek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chembiol.2012.12.009_bib1","doi-asserted-by":"crossref","first-page":"13995","DOI":"10.1021\/ja036417x","article-title":"Isolation of protein ligands from large peptoid libraries","volume":"125","author":"Alluri","year":"2003","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2012.12.009_bib2","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1002\/ana.21802","article-title":"Intrathecal pathogenic anti-aquaporin-4 antibodies in early neuromyelitis optica","volume":"66","author":"Bennett","year":"2009","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.chembiol.2012.12.009_bib3","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1021\/cc9000168","article-title":"On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density","volume":"11","author":"Chen","year":"2009","journal-title":"J.\u00a0Comb. Chem."},{"key":"10.1016\/j.chembiol.2012.12.009_bib4","doi-asserted-by":"crossref","first-page":"16516","DOI":"10.1074\/jbc.M111.227298","article-title":"Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1\/M23 isoforms and orthogonal arrays","volume":"286","author":"Crane","year":"2011","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.chembiol.2012.12.009_bib5","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0076-6879(96)67027-X","article-title":"Synthesis of N-substituted glycine peptoid libraries","volume":"267","author":"Figliozzi","year":"1996","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.chembiol.2012.12.009_bib6","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/ng.372","article-title":"Narcolepsy is strongly associated with the T-cell receptor alpha locus","volume":"41","author":"Hallmayer","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.chembiol.2012.12.009_bib7","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.M110.000786","article-title":"Exploring antibody recognition of sequence space through random-sequence peptide microarrays","volume":"10","author":"Halperin","year":"2011","journal-title":"Mol. Cell Proteomics"},{"key":"10.1016\/j.chembiol.2012.12.009_bib8","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jneuroim.2008.03.009","article-title":"Neuromyelitis optica and anti-aquaporin-4 antibodies measured by an enzyme-linked immunosorbent assay","volume":"196","author":"Hayakawa","year":"2008","journal-title":"J.\u00a0Neuroimmunol."},{"key":"10.1016\/j.chembiol.2012.12.009_bib9","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jaut.2012.07.008","article-title":"Astrocytic autoantibody of neuromyelitis optica (NMO-IgG) binds to aquaporin-4 extracellular loops, monomers, tetramers and high order arrays","volume":"40","author":"Iorio","year":"2012","journal-title":"J.\u00a0Autoimmun."},{"key":"10.1016\/j.chembiol.2012.12.009_bib10","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1001\/archneurol.2010.269","article-title":"Quantification and functional characterization of antibodies to native aquaporin 4 in neuromyelitis optica","volume":"67","author":"Kalluri","year":"2010","journal-title":"Arch. Neurol."},{"key":"10.1016\/j.chembiol.2012.12.009_bib11","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1212\/01.wnl.0000223346.09426.34","article-title":"Identification of new serum autoantibodies in neuromyelitis optica using protein microarrays","volume":"67","author":"Lalive","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.chembiol.2012.12.009_bib12","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/354082a0","article-title":"A new type of synthetic peptide library for identifying ligand-binding activity","volume":"354","author":"Lam","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2012.12.009_bib13","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1023\/A:1014538322185","article-title":"Identifying peptide ligands for cell surface receptors using cell-growth-on-bead assay and one-bead one-compound combinatorial library","volume":"24","author":"Lau","year":"2002","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.chembiol.2012.12.009_bib14","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1016\/S0140-6736(04)17551-X","article-title":"A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis","volume":"364","author":"Lennon","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.chembiol.2012.12.009_bib15","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1016\/S0960-894X(02)00379-7","article-title":"Developing site-specific immobilization strategies of peptides in a microarray","volume":"12","author":"Lesaicherre","year":"2002","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.chembiol.2012.12.009_bib16","doi-asserted-by":"crossref","first-page":"7750","DOI":"10.1021\/ja072027p","article-title":"Identification of a peptoid inhibitor of the proteasome 19S regulatory particle","volume":"129","author":"Lim","year":"2007","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2012.12.009_bib17","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1158\/1535-7163.1329.3.10","article-title":"Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells","volume":"3","author":"Mikawa","year":"2004","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.chembiol.2012.12.009_bib18","doi-asserted-by":"crossref","first-page":"e23112","DOI":"10.1371\/journal.pone.0023112","article-title":"Diagnosis of Alzheimer\u2019s disease based on disease-specific autoantibody profiles in human sera","volume":"6","author":"Nagele","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1016\/j.chembiol.2012.12.009_bib19","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S1474-4422(12)70133-3","article-title":"Aquaporin 4 and neuromyelitis optica","volume":"11","author":"Papadopoulos","year":"2012","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.chembiol.2012.12.009_bib20","doi-asserted-by":"crossref","first-page":"13829","DOI":"10.1074\/jbc.M112.344325","article-title":"Complement-dependent cytotoxicity in neuromyelitis optica requires aquaporin-4 protein assembly in orthogonal arrays","volume":"287","author":"Phuan","year":"2012","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.chembiol.2012.12.009_bib21","doi-asserted-by":"crossref","first-page":"9216","DOI":"10.1074\/jbc.M110.123000","article-title":"Identification of two major conformational aquaporin-4 epitopes for neuromyelitis optica autoantibody binding","volume":"286","author":"Pisani","year":"2011","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.chembiol.2012.12.009_bib22","doi-asserted-by":"crossref","first-page":"12672","DOI":"10.1073\/pnas.0501208102","article-title":"Protein \u201cfingerprinting\u201d in complex mixtures with peptoid microarrays","volume":"102","author":"Reddy","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chembiol.2012.12.009_bib23","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.cell.2010.11.054","article-title":"Identification of candidate IgG biomarkers for Alzheimer\u2019s disease via combinatorial library screening","volume":"144","author":"Reddy","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.chembiol.2012.12.009_bib24","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1002\/ana.22405","article-title":"Application of immunosignatures to the assessment of Alzheimer\u2019s disease","volume":"70","author":"Restrepo","year":"2011","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.chembiol.2012.12.009_bib25","doi-asserted-by":"crossref","first-page":"S66","DOI":"10.2144\/dec02-robinson","article-title":"Protein and peptide array analysis of autoimmune disease","volume":"33","author":"Robinson","year":"2002","journal-title":"Biotechniques"},{"key":"10.1016\/j.chembiol.2012.12.009_bib26","doi-asserted-by":"crossref","first-page":"9367","DOI":"10.1073\/pnas.89.20.9367","article-title":"Peptoids: a modular approach to drug discovery","volume":"89","author":"Simon","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chembiol.2012.12.009_bib27","doi-asserted-by":"crossref","first-page":"5744","DOI":"10.1021\/ja711193x","article-title":"A peptoid \u201cantibody surrogate\u201d that antagonizes VEGF receptor 2 activity","volume":"130","author":"Udugamasooriya","year":"2008","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2012.12.009_bib28","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1111\/j.1468-1331.2009.02897.x","article-title":"Different responses to interferon beta-1b treatment in patients with neuromyelitis optica and multiple sclerosis","volume":"17","author":"Uzawa","year":"2010","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.chembiol.2012.12.009_bib29","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1056\/NEJMoa051931","article-title":"Autoantibody signatures in prostate cancer","volume":"353","author":"Wang","year":"2005","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.chembiol.2012.12.009_bib30","first-page":"99","article-title":"Detection of anti-aquaporin-4 antibodies in neuromyelitis optica: current status of the assays","volume":"15","author":"Waters","year":"2008","journal-title":"Int. MS J."},{"key":"10.1016\/j.chembiol.2012.12.009_bib31","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1212\/WNL.0b013e318248dec1","article-title":"Serologic diagnosis of NMO: a multicenter comparison of aquaporin-4-IgG assays","volume":"78","author":"Waters","year":"2012","journal-title":"Neurology"},{"key":"10.1016\/j.chembiol.2012.12.009_bib32","doi-asserted-by":"crossref","first-page":"3750","DOI":"10.1073\/pnas.061028198","article-title":"The use of mRNA display to select high-affinity protein-binding peptides","volume":"98","author":"Wilson","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chembiol.2012.12.009_bib33","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1212\/01.wnl.0000216139.44259.74","article-title":"Revised diagnostic criteria for neuromyelitis optica","volume":"66","author":"Wingerchuk","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.chembiol.2012.12.009_bib34","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1021\/cc070023a","article-title":"Design and synthesis of a cell-permeable synthetic transcription factor mimic","volume":"9","author":"Xiao","year":"2007","journal-title":"J.\u00a0Comb. Chem."},{"key":"10.1016\/j.chembiol.2012.12.009_bib35","doi-asserted-by":"crossref","first-page":"10646","DOI":"10.1021\/ja00052a076","article-title":"Efficient method for the preparation of peptoids (oligo N-substituted glycines) by submonomer solid-phase synthesis","volume":"114","author":"Zuckermann","year":"1992","journal-title":"J.\u00a0Am. Chem. Soc."}],"container-title":["Chemistry & Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074552113000392?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1074552113000392?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T07:20:54Z","timestamp":1761031254000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1074552113000392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S1074552113000392"],"URL":"https:\/\/doi.org\/10.1016\/j.chembiol.2012.12.009","relation":{},"ISSN":["1074-5521"],"issn-type":[{"value":"1074-5521","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Discovery of Peptoid Ligands for Anti-Aquaporin 4 Antibodies","name":"articletitle","label":"Article Title"},{"value":"Chemistry & Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chembiol.2012.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}