{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T06:00:18Z","timestamp":1792821618341,"version":"4.5.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:00:00Z","timestamp":1773964800000},"content-version":"am","delay-in-days":384,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19 AI142784"],"award-info":[{"award-number":["U19 AI142784"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30 DK43351"],"award-info":[{"award-number":["P30 DK43351"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007028","name":"Leona M. and Harry B. Helmsley Charitable Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007028","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Chemical Biology"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.chembiol.2024.12.002","type":"journal-article","created":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T02:56:25Z","timestamp":1736045785000},"page":"498-510.e35","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Development of an FKBP12-recruiting chemical-induced proximity DNA-encoded library and its application to discover an autophagy potentiator"],"prefix":"10.1016","volume":"32","author":[{"given":"Zher Yin","family":"Tan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel K.A.","family":"Adade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiebin","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cody J.S.","family":"Hecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Salcius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingqi","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seungmin","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric J.","family":"Z\u00e9cri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel B.","family":"Graham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart L.","family":"Schreiber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5630-5167","authenticated-orcid":false,"given":"Ramnik J.","family":"Xavier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chembiol.2024.12.002_bib1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.cell.2020.12.020","article-title":"The Rise of Molecular Glues","volume":"184","author":"Schreiber","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.chembiol.2024.12.002_bib2","doi-asserted-by":"crossref","DOI":"10.1002\/cbic.202300712","article-title":"TAC-tics for Leveraging Proximity Biology in Drug Discovery","volume":"25","author":"Nalawansha","year":"2024","journal-title":"Chembiochem"},{"key":"10.1016\/j.chembiol.2024.12.002_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.100647","article-title":"Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs","volume":"296","author":"Alabi","year":"2021","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.chembiol.2024.12.002_bib4","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.chembiol.2020.07.020","article-title":"PROTACs: An Emerging Therapeutic Modality in Precision Medicine","volume":"27","author":"Nalawansha","year":"2020","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib5","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/s41586-020-2545-9","article-title":"Lysosome-targeting chimaeras for degradation of extracellular proteins","volume":"584","author":"Banik","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2024.12.002_bib6","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/s41589-021-00770-1","article-title":"LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation","volume":"17","author":"Ahn","year":"2021","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib7","doi-asserted-by":"crossref","first-page":"2807","DOI":"10.1021\/acs.jmedchem.9b01167","article-title":"Heterobifunctional Molecules Induce Dephosphorylation of Kinases-A Proof of Concept Study","volume":"63","author":"Yamazoe","year":"2020","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.chembiol.2024.12.002_bib8","doi-asserted-by":"crossref","first-page":"14052","DOI":"10.1021\/jacs.0c05537","article-title":"Phosphorylation-Inducing Chimeric Small Molecules","volume":"142","author":"Siriwardena","year":"2020","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2024.12.002_bib9","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.chembiol.2019.02.009","article-title":"Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription","volume":"26","author":"Struntz","year":"2019","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib10","article-title":"Targeted Protein Relocalization via Protein Transport Coupling","author":"Ng","year":"2023","journal-title":"bioRxiv"},{"key":"10.1016\/j.chembiol.2024.12.002_bib11","doi-asserted-by":"crossref","first-page":"26028","DOI":"10.1021\/jacs.3c06179","article-title":"Bifunctional Small Molecules That Induce Nuclear Localization and Targeted Transcriptional Regulation","volume":"145","author":"Gibson","year":"2023","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2024.12.002_bib12","doi-asserted-by":"crossref","first-page":"23281","DOI":"10.1021\/jacs.3c08307","article-title":"Rational Screening for Cooperativity in Small-Molecule Inducers of Protein\u2013Protein Associations","volume":"145","author":"Liu","year":"2023","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2024.12.002_bib13","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/s41586-024-07089-6","article-title":"Targeted protein degradation via intramolecular bivalent glues","volume":"627","author":"Hsia","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2024.12.002_bib14","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/0092-8674(91)90124-H","article-title":"Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes","volume":"66","author":"Liu","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.chembiol.2024.12.002_bib15","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0092-8674(94)90570-3","article-title":"RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs","volume":"78","author":"Sabatini","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.chembiol.2024.12.002_bib16","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/369756a0","article-title":"A mammalian protein targeted by G1-arresting rapamycin-receptor complex","volume":"369","author":"Brown","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2024.12.002_bib17","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1126\/science.1177319","article-title":"Identification of a primary target of thalidomide teratogenicity","volume":"327","author":"Ito","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.chembiol.2024.12.002_bib18","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/s41589-020-0469-1","article-title":"Unifying principles of bifunctional, proximity-inducing small molecules","volume":"16","author":"Gerry","year":"2020","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib19","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nrd.2016.211","article-title":"Induced protein degradation: an emerging drug discovery paradigm","volume":"16","author":"Lai","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.chembiol.2024.12.002_bib20","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/s41589-023-01458-4","article-title":"DNA-encoded library-enabled discovery of proximity-inducing small molecules","volume":"20","author":"Mason","year":"2024","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib21","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s43586-021-00084-5","article-title":"DNA-encoded chemical libraries","volume":"2","author":"Satz","year":"2022","journal-title":"Nat. Rev. Methods Primers"},{"key":"10.1016\/j.chembiol.2024.12.002_bib22","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.3748\/wjg.v16.i10.1258","article-title":"T300A polymorphism of ATG16L1 and susceptibility to inflammatory bowel diseases: a meta-analysis","volume":"16","author":"Cheng","year":"2010","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib23","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/nature13044","article-title":"A Crohn\u2019s disease variant in Atg16l1 enhances its degradation by caspase 3","volume":"506","author":"Murthy","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2024.12.002_bib24","doi-asserted-by":"crossref","first-page":"7741","DOI":"10.1073\/pnas.1407001111","article-title":"Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense","volume":"111","author":"Lassen","year":"2014","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chembiol.2024.12.002_bib25","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1021\/acschembio.2c00797","article-title":"Optimization of PROTAC ternary complex using DNA encoded library approach","volume":"18","author":"Chen","year":"2023","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib26","doi-asserted-by":"crossref","first-page":"17195","DOI":"10.1073\/pnas.2006560117","article-title":"Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface","volume":"117","author":"Shigdel","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chembiol.2024.12.002_bib27","article-title":"Discovery of fully synthetic FKBP12-mTOR molecular glues","author":"Robin","year":"2023","journal-title":"ChemRxiv"},{"key":"10.1016\/j.chembiol.2024.12.002_bib28","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/s41557-018-0187-4","article-title":"Rapamycin-inspired macrocycles with new target specificity","volume":"11","author":"Guo","year":"2019","journal-title":"Nat. Chem."},{"key":"10.1016\/j.chembiol.2024.12.002_bib29","doi-asserted-by":"crossref","first-page":"7575","DOI":"10.1021\/ja035176q","article-title":"A bifunctional molecule that displays context-dependent cellular activity","volume":"125","author":"Braun","year":"2003","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2024.12.002_bib30","doi-asserted-by":"crossref","first-page":"16314","DOI":"10.1002\/anie.201910124","article-title":"Bifunctional Small-Molecule Ligands of K-Ras Induce Its Association with Immunophilin Proteins","volume":"58","author":"Zhang","year":"2019","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1016\/j.chembiol.2024.12.002_bib31","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.3389\/fphar.2018.01425","article-title":"FKBP Ligands-Where We Are and Where to Go?","volume":"9","author":"Kolos","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib32","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1128\/MCB.00678-12","article-title":"Large FK506-binding proteins shape the pharmacology of rapamycin","volume":"33","author":"M\u00e4rz","year":"2013","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib33","doi-asserted-by":"crossref","first-page":"9925","DOI":"10.1021\/ja00075a008","article-title":"Design, synthesis, and kinetic evaluation of high-affinity FKBP ligands and the X-ray crystal structures of their complexes with FKBP12","volume":"115","author":"Holt","year":"1993","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2024.12.002_bib34","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1021\/ja00004a051","article-title":"Rapamycin and FK506 binding proteins (immunophilins)","volume":"113","author":"Fretz","year":"1991","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2024.12.002_bib35","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1038\/378641a0","article-title":"Crystal structures of human calcineurin and the human FKBP12\u2013FK506\u2013calcineurin complex","volume":"378","author":"Kissinger","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2024.12.002_bib36","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/0092-8674(95)90439-5","article-title":"X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex","volume":"82","author":"Griffith","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.chembiol.2024.12.002_bib37","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1126\/science.273.5272.239","article-title":"Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP","volume":"273","author":"Choi","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.chembiol.2024.12.002_bib38","doi-asserted-by":"crossref","first-page":"10225","DOI":"10.1021\/jacs.9b01203","article-title":"DNA Barcoding a Complete Matrix of Stereoisomeric Small Molecules","volume":"141","author":"Gerry","year":"2019","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2024.12.002_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cbpa.2019.08.008","article-title":"Recent achievements and current trajectories of diversity-oriented synthesis","volume":"56","author":"Gerry","year":"2020","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib40","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1038\/s41589-023-01270-0","article-title":"Remodeling oncogenic transcriptomes by small molecules targeting NONO","volume":"19","author":"Kathman","year":"2023","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib41","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1016\/j.molcel.2023.03.026","article-title":"Proteomic discovery of chemical probes that perturb protein complexes in human cells","volume":"83","author":"Lazear","year":"2023","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chembiol.2024.12.002_bib42","doi-asserted-by":"crossref","first-page":"7796","DOI":"10.1021\/acs.jmedchem.5b00785","article-title":"Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands","volume":"58","author":"Feng","year":"2015","journal-title":"J.\u00a0Med. Chem."},{"key":"10.1016\/j.chembiol.2024.12.002_bib43","doi-asserted-by":"crossref","first-page":"5563","DOI":"10.1021\/jacs.5b02150","article-title":"Discovery of a Small-Molecule Probe for V-ATPase Function","volume":"137","author":"Aldrich","year":"2015","journal-title":"J.\u00a0Am. Chem. Soc."},{"key":"10.1016\/j.chembiol.2024.12.002_bib44","doi-asserted-by":"crossref","first-page":"E4281","DOI":"10.1073\/pnas.1512289112","article-title":"Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics","volume":"112","author":"Kuo","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chembiol.2024.12.002_bib45","doi-asserted-by":"crossref","first-page":"2724","DOI":"10.1021\/cb400352d","article-title":"Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules","volume":"8","author":"Shaw","year":"2013","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib46","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/s41576-022-00562-w","article-title":"Autophagy genes in biology and disease","volume":"24","author":"Yamamoto","year":"2023","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.chembiol.2024.12.002_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.767456","article-title":"IL-1\u03b2 and the Intestinal Epithelial Tight Junction Barrier","volume":"12","author":"Kaminsky","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib48","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/s41556-018-0037-z","article-title":"Cargo recognition and degradation by selective autophagy","volume":"20","author":"Gatica","year":"2018","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib49","doi-asserted-by":"crossref","first-page":"2316","DOI":"10.1021\/acs.jcim.2c00041","article-title":"Machine Learning on DNA-Encoded Library Count Data Using an Uncertainty-Aware Probabilistic Loss Function","volume":"62","author":"Lim","year":"2022","journal-title":"J.\u00a0Chem. Inf. Model."},{"key":"10.1016\/j.chembiol.2024.12.002_bib50","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15548627.2020.1797280","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1","volume":"17","author":"Klionsky","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.chembiol.2024.12.002_bib51","doi-asserted-by":"crossref","first-page":"8023","DOI":"10.1074\/jbc.M900301200","article-title":"An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1","volume":"284","author":"Thoreen","year":"2009","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.chembiol.2024.12.002_bib52","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/nature07383","article-title":"Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production","volume":"456","author":"Saitoh","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2024.12.002_bib53","doi-asserted-by":"crossref","DOI":"10.1002\/cpim.107","article-title":"Inflammasome Assays In\u00a0Vitro and in Mouse Models","volume":"131","author":"Guo","year":"2020","journal-title":"Curr. Protoc. Immunol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib54","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.4049\/jimmunol.1502652","article-title":"The inflammatory bowel disease-associated autophagy gene Atg16L1T300A acts as a dominant negative variant in mice","volume":"198","author":"Gao","year":"2017","journal-title":"J.\u00a0Immunol."},{"key":"10.1016\/j.chembiol.2024.12.002_bib55","doi-asserted-by":"crossref","first-page":"17318","DOI":"10.1002\/ange.201905578","article-title":"Discovery of a potent GLUT inhibitor from a library of rapafucins by using 3D microarrays","volume":"131","author":"Guo","year":"2019","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1016\/j.chembiol.2024.12.002_bib56","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1016\/j.cell.2022.04.020","article-title":"PAAN\/MIF nuclease inhibition prevents neurodegeneration in Parkinson\u2019s disease","volume":"185","author":"Park","year":"2022","journal-title":"Cell"},{"key":"10.1016\/j.chembiol.2024.12.002_bib57","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/s41586-022-05213-y","article-title":"Brain-restricted mTOR inhibition with binary pharmacology","volume":"609","author":"Zhang","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2024.12.002_bib58","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1038\/291238a0","article-title":"Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines","volume":"291","author":"Hoiseth","year":"1981","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2024.12.002_bib59","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1053\/j.gastro.2013.08.035","article-title":"Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection","volume":"145","author":"Conway","year":"2013","journal-title":"Gastroenterology"},{"key":"10.1016\/j.chembiol.2024.12.002_bib60","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1016\/j.celrep.2015.05.045","article-title":"Integrated Genomics of Crohn\u2019s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy","volume":"11","author":"Begun","year":"2015","journal-title":"Cell Rep."},{"key":"10.1016\/j.chembiol.2024.12.002_bib61","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1091\/mbc.e03-09-0704","article-title":"In\u00a0vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker","volume":"15","author":"Mizushima","year":"2004","journal-title":"Mol. Biol. Cell"}],"container-title":["Cell Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451945624004914?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451945624004914?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:55:30Z","timestamp":1790805330000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451945624004914"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":61,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S2451945624004914"],"URL":"https:\/\/doi.org\/10.1016\/j.chembiol.2024.12.002","relation":{},"ISSN":["2451-9456"],"issn-type":[{"value":"2451-9456","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of an FKBP12-recruiting chemical-induced proximity DNA-encoded library and its application to discover an autophagy potentiator","name":"articletitle","label":"Article Title"},{"value":"Cell Chemical Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chembiol.2024.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}