{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:24:27Z","timestamp":1787243067347,"version":"build-2736575974"},"reference-count":55,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Cell Chemical Biology"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.chembiol.2026.06.001","type":"journal-article","created":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T15:01:06Z","timestamp":1783436466000},"page":"1205-1216.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["XPO1 inhibition induces NCOR1-Dependent oxidative stress to suppress hepatocellular carcinoma"],"prefix":"10.1016","volume":"33","author":[{"given":"Wei","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linmeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiaozhu","family":"Zuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuhui","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lili","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyi","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxin","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengxian","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Bernards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chembiol.2026.06.001_bib1","first-page":"209","article-title":"Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.chembiol.2026.06.001_bib2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s44178-025-00173-5","article-title":"Advances in neoadjuvant therapy for hepatocellular carcinoma","volume":"4","author":"Liu","year":"2025","journal-title":"Holist. Integ. Oncol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib3","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41575-022-00704-9","article-title":"Evolving therapeutic landscape of advanced hepatocellular carcinoma","volume":"20","author":"Yang","year":"2023","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/nrd.2018.168","article-title":"Drug repurposing: progress, challenges and recommendations","volume":"18","author":"Pushpakom","year":"2019","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.chembiol.2026.06.001_bib5","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.ejca.2017.01.013","article-title":"Exploratory analysis of biomarkers associated with clinical outcomes from the study of lenvatinib in differentiated cancer of the thyroid","volume":"75","author":"Tahara","year":"2017","journal-title":"Eur. J. Cancer"},{"key":"10.1016\/j.chembiol.2026.06.001_bib6","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1056\/NEJMoa060655","article-title":"Sorafenib in advanced clear-cell renal-cell carcinoma","volume":"356","author":"Escudier","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chembiol.2026.06.001_bib7","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/j.bcp.2011.12.016","article-title":"Nuclear export of proteins and drug resistance in cancer","volume":"83","author":"Turner","year":"2012","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib8","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1016\/j.chembiol.2024.05.016","article-title":"C646 degrades Exportin-1 to modulate p300 chromatin occupancy and function","volume":"31","author":"Chen","year":"2024","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib9","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aar7223","article-title":"Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas","volume":"10","author":"Saenz-Ponce","year":"2018","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.chembiol.2026.06.001_bib10","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.canlet.2017.02.029","article-title":"DDX17 nucleocytoplasmic shuttling promotes acquired gefitinib resistance in non-small cell lung cancer cells via activation of \u03b2-catenin","volume":"400","author":"Li","year":"2017","journal-title":"Cancer Lett."},{"key":"10.1016\/j.chembiol.2026.06.001_bib11","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1080\/15548627.2023.2252301","article-title":"KPT330 promotes the sensitivity of glioblastoma to olaparib by retaining SQSTM1 in the nucleus and disrupting lysosomal function","volume":"20","author":"Wang","year":"2024","journal-title":"Autophagy"},{"key":"10.1016\/j.chembiol.2026.06.001_bib12","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1200\/JCO.2017.75.5207","article-title":"Selective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma","volume":"36","author":"Vogl","year":"2018","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib13","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa1903455","article-title":"Oral Selinexor-Dexamethasone for Triple-Class Refractory Multiple Myeloma","volume":"381","author":"Chari","year":"2019","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.chembiol.2026.06.001_bib14","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/leu.2016.145","article-title":"KPT-8602, a second-generation inhibitor of XPO1-mediated nuclear export, is well tolerated and highly active against AML blasts and leukemia-initiating cells","volume":"31","author":"Etchin","year":"2017","journal-title":"Leukemia"},{"key":"10.1016\/j.chembiol.2026.06.001_bib15","doi-asserted-by":"crossref","first-page":"5747","DOI":"10.1158\/1078-0432.CCR-20-1315","article-title":"The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia","volume":"26","author":"Verbeke","year":"2020","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.chembiol.2026.06.001_bib16","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1158\/1078-0432.CCR-16-1333","article-title":"Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer","volume":"23","author":"Chen","year":"2017","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.chembiol.2026.06.001_bib17","doi-asserted-by":"crossref","first-page":"30773","DOI":"10.18632\/oncotarget.25637","article-title":"Selinexor reduces the expression of DNA damage repair proteins and sensitizes cancer cells to DNA damaging agents","volume":"9","author":"Kashyap","year":"2018","journal-title":"Oncotarget"},{"key":"10.1016\/j.chembiol.2026.06.001_bib18","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1053\/j.gastro.2024.01.025","article-title":"Dual Inhibition of CDK4\/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs","volume":"166","author":"Wang","year":"2024","journal-title":"Gastroenterology"},{"key":"10.1016\/j.chembiol.2026.06.001_bib19","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1038\/36894","article-title":"CRM1 is responsible for intracellular transport mediated by the nuclear export signal","volume":"390","author":"Fukuda","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.chembiol.2026.06.001_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2023.1190094","article-title":"Insights into the function of HDAC3 and NCoR1\/NCoR2 co-repressor complex in metabolic diseases","volume":"10","author":"Paluvai","year":"2023","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.chembiol.2026.06.001_bib21","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1002\/cbin.10973","article-title":"Role of NCoR1 in mitochondrial function and energy metabolism","volume":"42","author":"Lima","year":"2018","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.chembiol.2026.06.001_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1567874","article-title":"A complex role of chromogranin A and its peptides in inflammation, autoimmunity, and infections","volume":"16","author":"Maj","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib23","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1089\/ars.2018.7684","article-title":"Follistatin Protects Against Glomerular Mesangial Cell Apoptosis and Oxidative Stress to Ameliorate Chronic Kidney Disease","volume":"31","author":"Mehta","year":"2019","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.chembiol.2026.06.001_bib24","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/j.cell.2012.03.050","article-title":"A thrombospondin-dependent pathway for a protective ER stress response","volume":"149","author":"Lynch","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.chembiol.2026.06.001_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/ijms252413398","article-title":"Molecular Basis of Na, K\u2013ATPase Regulation of Diseases: Hormone and FXYD2 Interactions","volume":"25","author":"Cordeiro","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.chembiol.2026.06.001_bib26","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-72031-9","article-title":"MITF regulates IDH1, NNT, and a transcriptional program protecting melanoma from reactive oxygen species","volume":"14","author":"Roider","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.chembiol.2026.06.001_bib27","doi-asserted-by":"crossref","first-page":"99","DOI":"10.7150\/jca.118395","article-title":"CES3 promotes NSCLC progression via lipid metabolic reprogramming regulated by TFAP2A","volume":"17","author":"Luo","year":"2026","journal-title":"J. Cancer"},{"key":"10.1016\/j.chembiol.2026.06.001_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.tranon.2024.102077","article-title":"Cytochrome P450 F3 promotes colorectal cancer via inhibiting NRF2-mediated ferroptosis","volume":"48","author":"Xu","year":"2024","journal-title":"Transl. Oncol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib29","doi-asserted-by":"crossref","first-page":"6725","DOI":"10.1074\/jbc.M806893200","article-title":"Activation of Dual Oxidases Duox1 and Duox2","volume":"284","author":"Rigutto","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.chembiol.2026.06.001_bib30","doi-asserted-by":"crossref","first-page":"964","DOI":"10.3390\/cells10050964","article-title":"Elevated Interleukin-18 Receptor Accessory Protein Mediates Enhancement in Reactive Oxygen Species Production in Neutrophils of Systemic Lupus Erythematosus Patients","volume":"10","author":"Ma","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.chembiol.2026.06.001_bib31","first-page":"2585","article-title":"Circular RNA TTBK2 regulates cell proliferation, invasion and ferroptosis via miR-761\/ITGB8 axis in glioma","volume":"24","author":"Zhang","year":"2020","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"key":"10.1016\/j.chembiol.2026.06.001_bib32","article-title":"Nuclear receptor corepressors non-canonically drive glucocorticoid receptor-dependent activation of hepatic gluconeogenesis","volume":"6","author":"Ak","year":"2024","journal-title":"Nat. Metab."},{"key":"10.1016\/j.chembiol.2026.06.001_bib33","doi-asserted-by":"crossref","first-page":"3421","DOI":"10.1016\/j.molcel.2023.08.029","article-title":"RANK ligand converts the NCoR\/HDAC3 co-repressor to a PGC1\u03b2- and RNA-dependent co-activator of osteoclast gene expression","volume":"83","author":"Abe","year":"2023","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chembiol.2026.06.001_bib34","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1152\/physrev.00023.2017","article-title":"The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis","volume":"98","author":"Yamamoto","year":"2018","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.chembiol.2026.06.001_bib35","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1248\/bpb.b21-00466","article-title":"Disulfiram Chelated with Copper Promotes Apoptosis in Osteosarcoma via ROS\/Mitochondria Pathway","volume":"44","author":"Ren","year":"2021","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.chembiol.2026.06.001_bib36","article-title":"XPO1-dependent nuclear export as a target for cancer therapy","volume":"13","author":"Ng","year":"2020","journal-title":"J. Hematol. Oncol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib37","article-title":"Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor","volume":"52","author":"Zheng","year":"2013","journal-title":"Mol. cell"},{"key":"10.1016\/j.chembiol.2026.06.001_bib38","doi-asserted-by":"crossref","first-page":"8796","DOI":"10.1096\/fj.202000055RR","article-title":"PPAR\u03b1 and NCOR\/SMRT corepressor network in liver metabolic regulation","volume":"34","author":"Kang","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.chembiol.2026.06.001_bib39","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1016\/j.freeradbiomed.2010.09.021","article-title":"Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis","volume":"49","author":"Loor","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.chembiol.2026.06.001_bib40","doi-asserted-by":"crossref","first-page":"4461","DOI":"10.2174\/1381612826666200628022113","article-title":"Cancer Pro-oxidant Therapy Through Copper Redox Cycling: Repurposing Disulfiram and Tetrathiomolybdate","volume":"26","author":"Rieber","year":"2020","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.chembiol.2026.06.001_bib41","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.trecan.2025.04.009","article-title":"Prospects for understanding and exploiting the consequences of hyperactivation lethality","volume":"11","author":"Shaw","year":"2025","journal-title":"Trends Cancer"},{"key":"10.1016\/j.chembiol.2026.06.001_bib42","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.cell.2009.02.024","article-title":"Principles of cancer therapy: oncogene and non-oncogene addiction","volume":"136","author":"Luo","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.chembiol.2026.06.001_bib43","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.molcel.2022.11.014","article-title":"Proteome diversification by mRNA translation in cancer","volume":"83","author":"Kochavi","year":"2023","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chembiol.2026.06.001_bib44","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s44178-025-00167-3","article-title":"Application of biomarkers in the assessment and treatment of cancer-related fatigue","volume":"4","author":"Hu","year":"2025","journal-title":"Holist. Integ. Oncol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.cstres.2025.100108","article-title":"Reactive Oxygen Species in Cancer: Mechanistic Insights and Therapeutic Innovations","volume":"30","author":"Ma","year":"2025","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.chembiol.2026.06.001_bib46","first-page":"19","article-title":"Glucose metabolic dysregulation and oxidative stress in cholangiocarcinoma: molecular mechanisms, oncogenic drivers, and novel therapeutic targets","volume":"11","author":"Chanda","year":"2025","journal-title":"Hepatoma Res."},{"key":"10.1016\/j.chembiol.2026.06.001_bib47","doi-asserted-by":"crossref","DOI":"10.1126\/science.adk9167","article-title":"Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function","volume":"386","author":"Swamynathan","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.chembiol.2026.06.001_bib48","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1016\/j.devcel.2024.12.035","article-title":"DYRK1A-TGF-\u03b2 signaling axis determines sensitivity to OXPHOS inhibition in hepatocellular carcinoma","volume":"60","author":"Cao","year":"2025","journal-title":"Dev. Cell"},{"key":"10.1016\/j.chembiol.2026.06.001_bib49","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s13402-025-01142-w","article-title":"Ferroptosis in hematological malignancies: molecular mechanisms and therapeutic potential","volume":"49","author":"Liu","year":"2025","journal-title":"Cell. Oncol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib50","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.chembiol.2025.04.002","article-title":"N-acetyl-l-cysteine averts ferroptosis by fostering glutathione peroxidase 4","volume":"32","author":"Zheng","year":"2025","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.chembiol.2026.06.001_bib51","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1158\/1078-0432.CCR-24-3296","article-title":"Mitochondria Targeting of Oxidative Phosphorylation Inhibitors to Alleviate Hypoxia and Enhance Anticancer Treatment Efficacy","volume":"31","author":"Beerkens","year":"2025","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.chembiol.2026.06.001_bib52","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1158\/2159-8290.CD-19-0338","article-title":"Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11","volume":"9","author":"Lang","year":"2019","journal-title":"Cancer Discov."},{"key":"10.1016\/j.chembiol.2026.06.001_bib53","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20191692","article-title":"Efficient gene knockout in primary human and murine myeloid cells by non-viral delivery of CRISPR-Cas9","volume":"217","author":"Freund","year":"2020","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.chembiol.2026.06.001_bib54","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1186\/1471-2105-9-559","article-title":"WGCNA: an R package for weighted correlation network analysis","volume":"9","author":"Langfelder","year":"2008","journal-title":"BMC Bioinf."},{"key":"10.1016\/j.chembiol.2026.06.001_bib55","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.1093\/bioinformatics\/btw230","article-title":"Combenefit: an interactive platform for the analysis and visualization of drug combinations","volume":"32","author":"Di Veroli","year":"2016","journal-title":"Bioinformatics"}],"container-title":["Cell Chemical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451945626001996?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2451945626001996?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:34:14Z","timestamp":1787240054000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2451945626001996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":55,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S2451945626001996"],"URL":"https:\/\/doi.org\/10.1016\/j.chembiol.2026.06.001","relation":{},"ISSN":["2451-9456"],"issn-type":[{"value":"2451-9456","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"XPO1 inhibition induces NCOR1-Dependent oxidative stress to suppress hepatocellular carcinoma","name":"articletitle","label":"Article Title"},{"value":"Cell Chemical Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chembiol.2026.06.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}