{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:35:09Z","timestamp":1791311709648,"version":"4.3.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2004,12]]},"DOI":"10.1016\/j.chemosphere.2004.09.015","type":"journal-article","created":{"date-parts":[[2004,12,15]],"date-time":"2004-12-15T15:18:52Z","timestamp":1103123932000},"page":"1479-1488","source":"Crossref","is-referenced-by-count":402,"title":["Determination of antibiotic substances in hospital sewage water using solid phase extraction and liquid chromatography\/mass spectrometry and group analogue internal standards"],"prefix":"10.1016","volume":"57","author":[{"given":"Richard","family":"Lindberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per-\u00c5ke","family":"Jarnheimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magnus","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mats","family":"Tysklind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2004.09.015_bib1","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0045-6535(02)00769-5","article-title":"Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment","volume":"50","author":"Andreozzi","year":"2003","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib2","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1373\/49.7.1041","article-title":"Ion suppression in mass spectrometry","volume":"49","author":"Annesley","year":"2003","journal-title":"Clinical Chemistry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib3","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0021-9673(02)01355-9","article-title":"Determination of five nitroimidazoles in water by liquid chromatography-mass spectrometry","volume":"978","author":"Capitan-Vallvey","year":"2002","journal-title":"Journal of Chromatography A"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib4","doi-asserted-by":"crossref","first-page":"3632","DOI":"10.1021\/ac0015265","article-title":"Trace determination of fluoroquinolone antibacterial agents in urban wastewater by solid-phase extraction and liquid chromatography with fluorescence detection","volume":"73","author":"Golet","year":"2001","journal-title":"Analytical Chemistry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib5","doi-asserted-by":"crossref","first-page":"5455","DOI":"10.1021\/ac025762m","article-title":"Determination of fluoroquinolone antibacterial agents in sewage sludge and sludge-treated soil using accelerated solvent extraction followed by solid-phase extraction","volume":"74","author":"Golet","year":"2002","journal-title":"Analytical Chemistry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib6","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0021-9673(02)00083-3","article-title":"Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry","volume":"952","author":"Haller","year":"2002","journal-title":"Journal of Chromatography A"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib7","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1021\/ac015588m","article-title":"Determination of persistent tetracycline residues in soil fertilized with liquid manure by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry","volume":"74","author":"Hamscher","year":"2002","journal-title":"Analytical Chemistry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib8","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0021-9673(99)00378-7","article-title":"Detection and identification of sulphonamide drugs in municipal waste water by liquid chromatography coupled with electrospray ionization tandem mass spectrometry","volume":"854","author":"Hartig","year":"1999","journal-title":"Journal of Chromatography A"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib9","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s002449900449","article-title":"Primary DNA damage but not mutagenicity correlates with ciprofloxacin concentrations in German hospital wastewaters","volume":"36","author":"Hartmann","year":"1999","journal-title":"Archives of Environmental Contamination and Toxicology"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib10","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0021-9673(98)00335-5","article-title":"Determination of antibiotics in different water compartments via liquid chromatography-electrospray tandem mass spectrometry","volume":"815","author":"Hirsch","year":"1998","journal-title":"Journal of Chromatography A"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib11","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0048-9697(98)00337-4","article-title":"Occurrence of antibiotics in the aquatic environment","volume":"225","author":"Hirsch","year":"1999","journal-title":"The Science of the Total Environment"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib12","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1002\/rcm.1112","volume":"17","author":"Jemal","year":"2003","journal-title":"Rapid Communications in Mass Spectrometry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib13","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1021\/es011055j","article-title":"Pharmaceuticals, hormones, and other organic wastewater contaminants in US. streams, 1999\u20132000: a national reconnaissance","volume":"36","author":"Kolpin","year":"2002","journal-title":"Environmental Science and Technology"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib14","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1093\/jac\/dkg293","article-title":"Significance of antibiotics in the environment","volume":"52","author":"K\u00fcmmerer","year":"2003","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib15","doi-asserted-by":"crossref","first-page":"4640","DOI":"10.1021\/ac010514w","article-title":"Analysis of trace levels of sulphonamide and tetracycline antimicrobials in groundwater and surface water using solid-phase extraction and liquid chromatography\/mass spectrometry","volume":"73","author":"Lindsey","year":"2001","journal-title":"Analytical Chemistry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib16","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0021-9673(98)00281-7","article-title":"Analysis of antibiotics by liquid chromatography-mass spectrometry","volume":"812","author":"Niessen","year":"1998","journal-title":"Journal of Chromatography A"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib17","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/rcm.624","article-title":"Determination of selected sulfonamide antibiotics and trimethoprim in manure by electrospray and atmospheric pressure chemical ionization tandem mass spectrometry","volume":"16","author":"Pfeifer","year":"2002","journal-title":"Rapid Communications in Mass Spectrometry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib18","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0021-9673(01)01266-3","article-title":"Pharmaceuticals in groundwaters: analytical methods and results of a monitoring program in Baden-W\u00fcrttemberg, Germany","volume":"938","author":"Sacher","year":"2001","journal-title":"Journal of Chromatography A"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib19","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1002\/rcm.1139","article-title":"Matrix effects during analysis of plasma samples by electrospray and atmospheric pressure chemical ionization mass spectrometry: practical approaches to their elimination","volume":"17","author":"Schuhmacher","year":"2003","journal-title":"Rapid Communications in Mass Spectrometry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib20","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0021-9673(02)00948-2","article-title":"Validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification off 11(fluoro)quinolone antibiotics in swine kidney","volume":"976","author":"Toussaint","year":"2002","journal-title":"Journal of Chromatography A"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib21","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1002\/jps.2600670810","article-title":"Physicochemical properties of amphoteric \u03b2-lactam antibiotics I: stability, solubility, and dissolution behavior of amino penicillins as a function of pH","volume":"67","author":"Tsuji","year":"1978","journal-title":"Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib22","doi-asserted-by":"crossref","first-page":"4143","DOI":"10.1021\/ac970425c","article-title":"Study of 4-quinolone antibiotics in biological samples by short-column liquid chromatography coupled with electrospray ionization tandem mass spectrometry","volume":"69","author":"Volmer","year":"1997","journal-title":"Analytical Chemistry"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib23","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0378-4347(01)00334-6","article-title":"Quantification of metronidazole in small-volume biological samples using narrow-bore high-performance liquid chromatography","volume":"761","author":"Wibawa","year":"2001","journal-title":"Journal of Chromatography B"},{"key":"10.1016\/j.chemosphere.2004.09.015_bib24","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0021-9673(02)01196-2","article-title":"Alternative calibration approaches to compensate the effect of co-extracted matrix components in liquid chromatography-electrospray ionization tandem mass spectrometry analysis of pesticide residue in plant materials","volume":"973","author":"Zrostl\u00edkov\u00e1","year":"2002","journal-title":"Journal of Chromatography A"}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653504007842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653504007842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,31]],"date-time":"2019-01-31T12:21:40Z","timestamp":1548937300000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653504007842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["S0045653504007842"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2004.09.015","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2004,12]]}}}