{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:08:57Z","timestamp":1790662137126,"version":"4.1.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.chemosphere.2005.02.071","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T07:24:43Z","timestamp":1113549883000},"page":"1198-1203","source":"Crossref","is-referenced-by-count":63,"title":["Effects of heavy metals on sea urchin embryo development. Part 2. Interactive toxic effects of heavy metals in synthetic mine effluents"],"prefix":"10.1016","volume":"61","author":[{"given":"Naomasa","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Okamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2005.02.071_bib1","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/0043-1354(91)90043-P","article-title":"Combined effects of metals, an ecotoxicological evaluation","volume":"25","author":"Enserink","year":"1991","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2005.02.071_bib2","doi-asserted-by":"crossref","first-page":"225","DOI":"10.5134\/176165","article-title":"Marine pollution bioassay by sea urchin eggs, an attempt to enhance sensitivity","volume":"34","author":"Kobayashi","year":"1990","journal-title":"Publ. Seto Mar. Biol. Lab."},{"key":"10.1016\/j.chemosphere.2005.02.071_bib3","first-page":"54","article-title":"Synergism of inhibiting actions of heavy metals upon the fertilization and development of sea urchin eggs (in Japanese with English summary)","volume":"17","author":"Kobayashi","year":"1976","journal-title":"Sci. Eng. Rev. Doshisha Univ."},{"key":"10.1016\/j.chemosphere.2005.02.071_bib4","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/j.chemosphere.2003.11.052","article-title":"Effects of heavy metals on sea urchin embryo development. 1. Tracing the cause by the effects","volume":"55","author":"Kobayashi","year":"2004","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2005.02.071_bib5","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/etc.5620130115","article-title":"Ecotoxicity of mixtures of metals to the Zebra mussel Dreissena polymorpha","volume":"13","author":"Kraak","year":"1994","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.chemosphere.2005.02.071_bib6","series-title":"The sea urchin embryo","article-title":"Animalization and vegetalization","author":"Lallier","year":"1975"},{"key":"10.1016\/j.chemosphere.2005.02.071_bib7","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1002\/etc.5620141113","article-title":"Comparative acute toxicity of a synthetic mine effluent to Ceriodaphnia dubia, larval fathead minnow and the freshwater mussel Anodonta imbecilis","volume":"14","author":"Masnado","year":"1995","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.chemosphere.2005.02.071_bib8","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/BF00393631","article-title":"Toxicity of zinc, cadmium and copper to the shrimp Callianassa australiensis. II. Effects of paired and triad combinations of metals","volume":"64","author":"Negilski","year":"1981","journal-title":"Mar. Biol."},{"key":"10.1016\/j.chemosphere.2005.02.071_bib9","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1007\/s00128-003-0026-0","article-title":"Toxicity of cadmium\u2013copper\u2013nickel\u2013zinc mixtures to larval purple sea urchins Strongylocentrotus purpuratus","volume":"70","author":"Phillips","year":"2003","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.chemosphere.2005.02.071_bib10","series-title":"Echinoderms","first-page":"867","article-title":"Developmental toxicity of heavy metals in echinoid Paracentrotus lividus, effects of multi-element exposures","author":"Warnau","year":"1998"}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653505003541?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653505003541?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T10:29:27Z","timestamp":1550053767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653505003541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0045653505003541"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2005.02.071","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}