{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T07:25:02Z","timestamp":1770017102582,"version":"3.49.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.chemosphere.2007.11.036","type":"journal-article","created":{"date-parts":[[2008,1,2]],"date-time":"2008-01-02T22:33:16Z","timestamp":1199313196000},"page":"1369-1376","source":"Crossref","is-referenced-by-count":42,"title":["Arsenate and perchlorate toxicity, growth effects, and thyroid histopathology in hypothyroid zebrafish Danio rerio"],"prefix":"10.1016","volume":"71","author":[{"given":"Fujun","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angella","family":"Gentles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher W.","family":"Theodorakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2007.11.036_bib1","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1897\/01-386","article-title":"Mixture toxicity and its modeling by quantitative structure\u2013activity relationships","volume":"22","author":"Altenburger","year":"2003","journal-title":"Envrion. Toxicol. Chem."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib2","unstructured":"[ASTM], American Society for Testing and Materials. 2003. Standard Guide for Conducting Acute Toxicity Tests with Fishes, Macroinvertebrates, and Amphibians. E 729-96. Annual Book of ASTM Standards, Vol. 11.04. Philadelphia, ASTM."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib3","unstructured":"ATSDR 1998. Toxicological Profile for Arsenic (Update). Prepared by Research Triangel Institute, Atlandta, Georgia p. 349."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib4","doi-asserted-by":"crossref","first-page":"5190","DOI":"10.1021\/es0484505","article-title":"Perchlorate affects thyroid function in eastern mosquitofish (Gambusiaholbrook) at environmentally relevant concentrations","volume":"39","author":"Bradford","year":"2006","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib5","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1016\/j.chemosphere.2005.08.073","article-title":"Uptake and elimination of perchlorate eastern mosquitofish","volume":"63","author":"Bradford","year":"2006","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib6","doi-asserted-by":"crossref","first-page":"13011","DOI":"10.1073\/pnas.94.24.13011","article-title":"The role of thyroid hormone in zebrafish and axolotl development","volume":"94","author":"Brown","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib7","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1897\/03-242","article-title":"Contaminant effects on the teleost fish thyroid","volume":"23","author":"Brown","year":"2004","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib8","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1897\/05-454R.1","article-title":"Perchlorate induces hermaphroditism in threespine sticklebacks","volume":"25","author":"Burkhardt","year":"2006","journal-title":"Environ. Toxicol. Chem."},{"issue":"3","key":"10.1016\/j.chemosphere.2007.11.036_bib9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1577\/H04-019.1","article-title":"Exposure to perchlorate induces the formation of macrophage aggregates in the trunk kidney of zebrafish and mosquitofish","volume":"6","author":"Capps","year":"2004","journal-title":"J. Aquat. Anim. Health"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib10","series-title":"Perchlorate Ecotoxicology. Society of Environmental Toxicology and Chemistry (SETAC)","first-page":"125","article-title":"Effects of perchlorate in amphibians","author":"Carr","year":"2006"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib11","first-page":"130","article-title":"Ammonium perchlorate disruption of thyroid function in natural amphibian populations, assessment and potential impact","author":"Carr","year":"2003"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib12","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1289\/ehp.7333","article-title":"Effects of ammonium perchlorate on thyroid function in developing fathead minnows, Pimephales promelas","volume":"113","author":"Crane","year":"2005","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib13","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/BF02143194","article-title":"The use of sigmoidal dose\u2013response curves in soil ecotoxicological research","volume":"84","author":"Haanstra","year":"1985","journal-title":"Plant Soil"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib14","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1006\/phrs.1998.0366","article-title":"Radioiodine treatment and oxidative stress in thyroidectomised patients for differentiated thyroid cancers","volume":"38","author":"Konuko\u011fu","year":"1998","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib15","doi-asserted-by":"crossref","unstructured":"Kuwabara, J.S., Fuller, C.C., 2003. Toxic substances in surface waters and sediments \u2013 a study to assess the effects of arsenic-contaminated alluvial sediment in Whitewood Creek, South Dakota. US Geological Survey Toxic Substances Hydrology Program Professional Paper 1681. US Geological Survey, Washington, DC.","DOI":"10.3133\/pp1681"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib16","first-page":"237","article-title":"Joint toxicity of arsenate and perchlorate to zebrafish Danio rerio larvae","volume":"226","author":"Liu","year":"2005","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib17","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1016\/j.chemosphere.2006.05.030","article-title":"Uptake, accumulation and depuration of perchlorate and arsenate in zebrafish (Daniorerio)","volume":"10","author":"Liu","year":"2006","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib18","doi-asserted-by":"crossref","first-page":"3429","DOI":"10.1021\/es052538g","article-title":"Thyrotoxicity of arsenate, perchlorate, and their mixture in zebrafish Daniorerio","volume":"40","author":"Liu","year":"2006","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib19","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1073\/pnas.98.4.1643","article-title":"Induction of oxyradicals by arsenic, implication for mechanism of genotoxicity","volume":"98","author":"Liu","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib20","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1046\/j.1432-0436.2002.700104.x","article-title":"Thyroid hormones are important for embryonic to larval transitory phase in zebrafish","volume":"70","author":"Liu","year":"2002","journal-title":"Differentiation"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib21","series-title":"Perchlorate Ecotoxicology. Society of Environmental Toxicology and Chemistry (SETAC)","first-page":"1","article-title":"State of the science: background, history, and occurence","author":"Mayer","year":"2006"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib22","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1385\/BTER:90:1-3:83","article-title":"Fish arsenic blood arsenic, selenium, and T4, T3 ratio","volume":"90","author":"Meltzer","year":"2002","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib23","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1897\/04-270R.1","article-title":"Novel biomarkers of perchlorate exposure in zebrafish","volume":"24","author":"Mukhi","year":"2005","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib24","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1093\/toxsci\/kfm001","article-title":"Effects of prolonged exposure to perchlorate on thyroid and reproductive function in zebrafish","volume":"96","author":"Mukhi","year":"2007","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib25","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.ygcen.2006.11.013","article-title":"Effects of larval\u2013juvenile treatment with perchlorate and co-treatment with thyroxine on zebrafish sex ratios","volume":"150","author":"Mukhi","year":"2007","journal-title":"Gen. Comp. Endocrinol."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib26","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1007\/s00128-004-0547-1","article-title":"Food chain transfer of perchlorate in largemouth bass, Micropterussalmoides","volume":"74","author":"Park","year":"2005","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib27","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.ecoenv.2005.04.002","article-title":"The thyroid endocrine disruptor perchlorate affects reproduction, growth, and survival of mosquitofish","volume":"63","author":"Park","year":"2006","journal-title":"Ecotox. Environ. Saf."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib28","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1002\/etc.5620220520","article-title":"Effects of ammonium perchlorate on the reproductive performance and thyroid follicle histology of zebrafish","volume":"22","author":"Pati\u00f1o","year":"2003","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib29","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0166-445X(90)90036-O","article-title":"Arsenic in aquatic organisms, a review, emphasizing chemical speciation","volume":"16","author":"Phillips","year":"1990","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib30","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1023\/A:1016715502717","article-title":"Preliminary assessment of perchlorate in ecological receptors at the Longhorn Army Ammunition Plant. LHAAP., Karnack, Texas","volume":"10","author":"Smith","year":"2001","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib31","series-title":"Perchlorate Ecotoxicology. Society of Environmental Toxicology and Chemistry (SETAC)","first-page":"155","article-title":"Perchlorate effects in fish","author":"Theodorakis","year":"2006"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s10646-005-0040-6","article-title":"Thyroid endocrine disruption in stonerollers and cricket frogs from perchlorate-contaminated streams in east-central Texas","volume":"15","author":"Theodorakis","year":"2006","journal-title":"Ecotoxicology"},{"key":"10.1016\/j.chemosphere.2007.11.036_bib33","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.envpol.2005.04.030","article-title":"Perchlorate in fish from a contaminated site in east-central Texas","volume":"139","author":"Theodorakis","year":"2006","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib34","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/jema.1999.0274","article-title":"Issues in managing the risks associated with perchlorate in drinking water","volume":"56","author":"Urbansky","year":"1999","journal-title":"J. Environ. Manage."},{"key":"10.1016\/j.chemosphere.2007.11.036_bib35","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S1096-4959(00)00309-2","article-title":"Thyroid hormones regulate lipid peroxidation and antioxidant enzyme activities in Anabastestudineus (Bloch)","volume":"128","author":"Varghese","year":"2001","journal-title":"Comp. Biochem. Physiol. B."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653507013835?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653507013835?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T12:37:05Z","timestamp":1557146225000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653507013835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S0045653507013835"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2007.11.036","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}