{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T22:29:03Z","timestamp":1783549743930,"version":"3.55.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.chemosphere.2014.08.003","type":"journal-article","created":{"date-parts":[[2014,8,30]],"date-time":"2014-08-30T21:00:22Z","timestamp":1409432422000},"page":"336-342","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"special_numbering":"C","title":["Associations of total arsenic in drinking water, hair and nails with serum vascular endothelial growth factor in arsenic-endemic individuals in Bangladesh"],"prefix":"10.1016","volume":"120","author":[{"given":"Mashiur","family":"Rahman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah Al","family":"Mamun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Rezaul","family":"Karim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khairul","family":"Islam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan Al","family":"Amin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shakhawoat","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Imam","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahangir Alam","family":"Saud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu Shadat Mohammod","family":"Noman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Miyataka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seiichiro","family":"Himeno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2014.08.003_b0005","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1476-069X-9-36","article-title":"Association between arsenic exposure and plasma cholinesterase activity: a population based study in Bangladesh","volume":"9","author":"Ali","year":"2010","journal-title":"Environ. Health"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0010","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1038\/bjc.1998.158","article-title":"Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology","volume":"77","author":"Banks","year":"1998","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0015","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1021\/tx100191t","article-title":"Arsenite induces endothelial cell permeability increase through a reactive oxygen species\u2013vascular endothelial growth factor pathway","volume":"23","author":"Bao","year":"2010","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0020","unstructured":"British Geological Survey. Arsenic contamination of ground water in Bangladesh. 2001, <http:\/\/www.bgs.ac.uk\/research\/groundwater\/health\/arsenic\/Bangladesh\/>, (accessed 24.07.14)."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0025","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/ijpg.271","article-title":"Tube wells and arsenic in Bangladesh: challenging a public health success story","volume":"9","author":"Caldwell","year":"2003","journal-title":"Int. J. Popul. Geogr."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0030","doi-asserted-by":"crossref","first-page":"L1075","DOI":"10.1152\/ajplung.00251.2005","article-title":"Endothelin-mediated increases in lung VEGF content promote vascular leak in young rats exposed to viral infection and hypoxia","volume":"289","author":"Carpenter","year":"2005","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0035","doi-asserted-by":"crossref","first-page":"741","DOI":"10.2105\/AJPH.94.5.741","article-title":"Cancer burden from arsenic in drinking water in Bangladesh","volume":"94","author":"Chen","year":"2004","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0040","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF02784067","article-title":"Determination of total arsenic concentrations in nails by inductively coupled plasma mass spectrometry","volume":"67","author":"Chen","year":"1999","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0045","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.taap.2006.12.032","article-title":"Arsenic and diabetes and hypertension in human populations: a review","volume":"222","author":"Chen","year":"2007","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0050","doi-asserted-by":"crossref","first-page":"d2431","DOI":"10.1136\/bmj.d2431","article-title":"Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort study","volume":"342","author":"Chen","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0055","first-page":"1296","article-title":"Incidence of internal cancers and ingested inorganic arsenic: a seven-year follow-up study in Taiwan","volume":"55","author":"Chiou","year":"1995","journal-title":"Cancer Res."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0060","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/scientificamerican0804-86","article-title":"Arsenic crisis in Bangladesh","volume":"291","author":"Chowdhury","year":"2004","journal-title":"Sci. Am."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0065","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/sj.leu.2402124","article-title":"Elevated vascular endothelial growth factor (VEGF) serum levels in idiopathic myelofibrosis","volume":"15","author":"Di Raimondo","year":"2001","journal-title":"Leukemia"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0070","doi-asserted-by":"crossref","first-page":"48066","DOI":"10.1074\/jbc.M106282200","article-title":"Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite","volume":"276","author":"Duyndam","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0075","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1038\/nrc909","article-title":"VEGF and the quest for tumour angiogenesis factors","volume":"2","author":"Ferrara","year":"2002","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0080","doi-asserted-by":"crossref","first-page":"C812","DOI":"10.1152\/ajpcell.1999.276.4.C812","article-title":"Hypoxia induces permeability in brain micro vessel endothelial cells via VEGF and NO","volume":"276","author":"Fischer","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0085","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1093\/humrep\/deg326","article-title":"Levels of vascular endothelial growth factor (VEGF) in serum of patients with endometriosis","volume":"18","author":"Gagn\u00e9","year":"2003","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0090","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1023\/B:MCBI.0000007259.65742.16","article-title":"Arsenic induces HIF-1 alpha and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells","volume":"255","author":"Gao","year":"2004","journal-title":"Mol. Cell Biochem."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0095","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1159\/000012095","article-title":"Thrombocytes are the major source for soluble vascular endothelial growth factor in peripheral blood","volume":"58","author":"Gunsilius","year":"2000","journal-title":"Oncology"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0100","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.taap.2011.12.023","article-title":"Elevated levels of plasma Big endothelin-1 and its relation to hypertension and skin lesions in individuals exposed to arsenic","volume":"259","author":"Hossain","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0105","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1210\/mend-5-12-1806","article-title":"The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA","volume":"5","author":"Houck","year":"1991","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0110","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/1476-069X-10-64","article-title":"Dose\u2013response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study in Bangladesh","volume":"10","author":"Islam","year":"2011","journal-title":"Environ. Health"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0115","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/toxsci\/kft130","article-title":"Increases in oxidized low density lipoprotein and other inflammatory and adhesion molecules with a concomitant decrease in high density lipoprotein in the individuals exposed to arsenic in Bangladesh","volume":"135","author":"Karim","year":"2013","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0120","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.atherosclerosis.2006.07.025","article-title":"Serum VEGF-as a prognostic factor of atherosclerosis","volume":"194","author":"Kimura","year":"2007","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0125","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/oxfordjournals.aje.a117031","article-title":"Ingested inorganic arsenic and prevalence of diabetes mellitus","volume":"139","author":"Lai","year":"1994","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0130","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1126\/science.2479986","article-title":"Vascular endothelial growth factor is a secreted angiogenic mitogen","volume":"246","author":"Leung","year":"1989","journal-title":"Science"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0135","doi-asserted-by":"crossref","first-page":"e20858","DOI":"10.1371\/journal.pone.0020858","article-title":"Role and mechanism of arsenic in regulating angiogenesis","volume":"6","author":"Liu","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0140","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1289\/ehp.6866","article-title":"The effect of arsenic mitigation interventions on disease burden in Bangladesh","volume":"112","author":"Lokuge","year":"2004","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0145","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S0891-5849(02)01005-5","article-title":"Redox signaling in vascular angiogenesis","volume":"33","author":"Maulik","year":"2002","journal-title":"Free Radical Biol. Med."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0150","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1093\/ije\/27.5.871","article-title":"Arsenic levels in drinking water and the prevalence of skin lesions in West Bengal","volume":"27","author":"Mazumder","year":"1998","journal-title":"India. Int. J. Epidemiol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0155","first-page":"6","article-title":"Arsenic in drinking water and cerebrovascular disease, diabetes mellitus, and kidney disease in Michigan: a standardized mortality ratio analysis","volume":"4","author":"Meliker","year":"2007","journal-title":"Environ. Health."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0160","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.taap.2010.01.004","article-title":"Arsenic promotes angiogenesis in vitro via a heme oxygenase-1-dependent mechanism","volume":"244","author":"Meng","year":"2010","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0165","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1073\/pnas.94.2.663","article-title":"Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets","volume":"94","author":"Mohle","year":"1997","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0170","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1096\/fasebj.13.1.9","article-title":"Vascular endothelial growth factor (VEGF) and its receptors","volume":"13","author":"Neufeld","year":"1999","journal-title":"FASEB J."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0175","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1200\/JCO.2001.19.4.1207","article-title":"Clinical implications of circulating angiogenic factors in cancer patients","volume":"19","author":"Poon","year":"2001","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0180","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1182\/blood.V96.4.1525","article-title":"Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis","volume":"96","author":"Roboz","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0185","doi-asserted-by":"crossref","first-page":"20331","DOI":"10.1074\/jbc.M411275200","article-title":"The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism","volume":"280","author":"Roybal","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0190","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.atherosclerosis.2009.01.031","article-title":"Are plasma VEGF and its soluble receptor sFlt-1 atherogenic risk factors? Cross-sectional data from the SAPHIR study","volume":"206","author":"Sandhofer","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0195","doi-asserted-by":"crossref","first-page":"95","DOI":"10.2174\/1568011033353452","article-title":"Vascular endothelial cell growth factor (VEGF), an emerging target for cancer chemotherapy","volume":"3","author":"Shinkaruk","year":"2003","journal-title":"Curr. Med. Chem. Anticancer Agents."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0200","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1038\/jes.2008.73","article-title":"Increased lung cancer risks are similar whether arsenic is ingested or inhaled","volume":"19","author":"Smith","year":"2009","journal-title":"J. Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0205","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1021\/tx034193q","article-title":"Signaling pathways for arsenic-stimulated vascular endothelial growth factor-a expression in primary vascular smooth muscle cells","volume":"17","author":"Soucy","year":"2004","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0210","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1248\/bpb.34.1785","article-title":"Vascular endothelial growth factor (VEGF), VEGF receptors and their inhibitors for antiangiogenic tumor therapy","volume":"34","author":"Takahashi","year":"2011","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0215","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.mrrev.2006.02.001","article-title":"Arsenic in the aetiology of cancer","volume":"612","author":"Tapio","year":"2006","journal-title":"Mutat. Res."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0220","doi-asserted-by":"crossref","first-page":"11947","DOI":"10.1016\/S0021-9258(18)99049-6","article-title":"The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing","volume":"266","author":"Tischer","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0225","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0021-9150(95)05693-9","article-title":"Dose\u2013response relationship between peripheral vascular disease and ingested inorganic arsenic among residents in blackfoot disease endemic villages in Taiwan","volume":"120","author":"Tseng","year":"1996","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0230","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.cbi.2008.07.001","article-title":"Arsenic-induced neurotoxicity in relation to toxicokinetics: effects on sciatic nerve proteins","volume":"176","author":"Vahidnia","year":"2008","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0235","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1021\/es702316k","article-title":"Flushing history as a hydrogeological control on the regional distribution of arsenic in shallow groundwater of the Bengal Basin","volume":"42","author":"van Geen","year":"2008","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0240","first-page":"2187","article-title":"Platelet: transporter of vascular endothelial growth factor","volume":"3","author":"Verheul","year":"1997","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0245","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1006\/cyto.1997.0297","article-title":"Activated human neutrophils express vascular endothelial growth factor (VEGF)","volume":"10","author":"Webb","year":"1998","journal-title":"Cytokine"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0250","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1038\/nature03987","article-title":"Pathophysiological consequences of VEGF-induced vascular permeability","volume":"437","author":"Weis","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.chemosphere.2014.08.003_b0255","doi-asserted-by":"crossref","first-page":"5780","DOI":"10.3748\/wjg.v12.i36.5780","article-title":"Inhibitory effect of arsenic trioxide on angiogenesis and expression of vascular endothelial growth factor in gastric cancer","volume":"12","author":"Xiao","year":"2006","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.chemosphere.2014.08.003_b0260","first-page":"704","article-title":"Inhibited proliferation of B-lymphoma Raji cells and down-regulated expression of VEGF by arsenic trioxide","volume":"14","author":"Yu","year":"2006","journal-title":"Zhongguo Shi Yan Xue Ye Xue Za Zhi."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653514009643?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653514009643?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,4,15]],"date-time":"2022-04-15T20:52:18Z","timestamp":1650055938000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653514009643"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":52,"alternative-id":["S0045653514009643"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2014.08.003","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Associations of total arsenic in drinking water, hair and nails with serum vascular endothelial growth factor in arsenic-endemic individuals in Bangladesh","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2014.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}