{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T12:31:45Z","timestamp":1788093105075,"version":"build-2803163510"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002947","name":"Anhui Medical University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002947","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1016\/j.chemosphere.2020.126668","type":"journal-article","created":{"date-parts":[[2020,4,5]],"date-time":"2020-04-05T23:27:52Z","timestamp":1586129272000},"page":"126668","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":97,"special_numbering":"C","title":["Maternal air pollution exposure and congenital heart defects in offspring: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"253","author":[{"given":"Cheng-Yang","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Guo","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da-Yan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng-Xuan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiu-Jun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2020.126668_bib1","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.envres.2013.03.005","article-title":"Air pollution and congenital heart defects","volume":"124","author":"Agay-Shay","year":"2013","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/MOP.0b013e32832925cc","article-title":"Epigenetics and environmental chemicals","volume":"21","author":"Baccarelli","year":"2009","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1016\/j.chemosphere.2020.126668_bib3","first-page":"1","article-title":"Environmental and individual exposure and the risk of congenital anomalies: a review of recent epidemiological evidence","volume":"42","author":"Baldacci","year":"2018","journal-title":"Epidemiol. Prev."},{"key":"10.1016\/j.chemosphere.2020.126668_bib4","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.envres.2013.10.008","article-title":"Effects of fine particulate matter and its constituents on low birth weight among full-term infants in California","volume":"128","author":"Basu","year":"2014","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib5","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1002\/bdra.20403","article-title":"Seeking causes: classifying and evaluating congenital heart defects in etiologic studies. Birth defects research","volume":"79","author":"Botto","year":"2007","journal-title":"Part A, Clinical and molecular teratology"},{"key":"10.1016\/j.chemosphere.2020.126668_bib6","doi-asserted-by":"crossref","DOI":"10.1136\/archdischild-2016-311845","article-title":"Estimating Global Burden of Disease due to congenital anomaly: an analysis of European data","volume":"103","author":"Boyle","year":"2018","journal-title":"Arch. Dis. Child. Fetal Neonatal Ed."},{"key":"10.1016\/j.chemosphere.2020.126668_bib7","doi-asserted-by":"crossref","first-page":"7642","DOI":"10.3390\/ijerph110807642","article-title":"Effects of air pollution on the risk of congenital anomalies: a systematic review and meta-analysis","volume":"11","author":"Chen","year":"2014","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.chemosphere.2020.126668_bib8","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.envres.2009.11.001","article-title":"Residential mobility during pregnancy and the potential for ambient air pollution exposure misclassification","volume":"110","author":"Chen","year":"2010","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib9","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/j.amjcard.2011.07.022","article-title":"Maternal and paternal environmental risk factors, metabolizing GSTM1 and GSTT1 polymorphisms, and congenital heart disease","volume":"108","author":"Cresci","year":"2011","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib10","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.envres.2011.01.022","article-title":"Ambient air pollution and congenital heart disease: a register-based study","volume":"111","author":"Dadvand","year":"2011","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib11","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/aje\/kwq342","article-title":"Association between maternal exposure to ambient air pollution and congenital heart disease: a register-based spatiotemporal analysis","volume":"173","author":"Dadvand","year":"2011","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib12","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1136\/oem.2009.045997","article-title":"Ambient air pollution and risk of congenital anomalies in England, 1991-1999","volume":"67","author":"Dolk","year":"2010","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.chemosphere.2020.126668_bib13","doi-asserted-by":"crossref","DOI":"10.1097\/01.ede.0000362295.63842.4f","article-title":"Air Pollution and Risk of Congenital Anomalies in England, 1991-99","volume":"20","author":"Dolk","year":"2009","journal-title":"Epidemiology"},{"key":"10.1016\/j.chemosphere.2020.126668_bib14","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.envres.2014.08.024","article-title":"The possible association between exposure to air pollution and the risk for congenital malformations","volume":"135","author":"Farhi","year":"2014","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib15","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/j.1747-0803.2011.00581.x","article-title":"How do we define congenital heart defects for scientific studies?","volume":"7","author":"Garne","year":"2012","journal-title":"Congenit. Heart Dis."},{"key":"10.1016\/j.chemosphere.2020.126668_bib16","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.envres.2013.11.002","article-title":"Congenital anomalies among live births in a high environmental risk area--a case-control study in Brindisi (southern Italy)","volume":"128","author":"Gianicolo","year":"2014","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib17","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1093\/aje\/kwi189","article-title":"Relation between ambient air quality and selected birth defects, seven county study, Texas, 1997-2000","volume":"162","author":"Gilboa","year":"2005","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envres.2015.12.010","article-title":"Maternal exposure to traffic-related air pollution and birth defects in Massachusetts","volume":"146","author":"Girguis","year":"2016","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0005408","article-title":"Ambient air pollution and birth defects in brisbane, Australia","volume":"4","author":"Hansen","year":"2009","journal-title":"PloS One"},{"key":"10.1016\/j.chemosphere.2020.126668_bib20","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1289\/ehp.1408798","article-title":"Geographic variation in the association between ambient fine particulate matter (PM2.5) and term low birth weight in the United States","volume":"124","author":"Hao","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2020.126668_bib21","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.scitotenv.2018.11.284","article-title":"Prenatal exposure to PM2.5 and congenital heart diseases in taiwan","volume":"655","author":"Huang","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2020.126668_bib22","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000001883","article-title":"Air pollution and the risk of cardiac defects: a population-based case-control study","volume":"94","author":"Hwang","year":"2015","journal-title":"Medicine"},{"key":"10.1016\/j.chemosphere.2020.126668_bib23","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s00246-006-1447-4","article-title":"Nomenclature and databases - the past, the present, and the future : a primer for the congenital heart surgeon","volume":"28","author":"Jacobs","year":"2007","journal-title":"Pediatr. Cardiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib24","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1159\/000275918","article-title":"Higher fish consumption in pregnancy may confer protection against the harmful effect of prenatal exposure to fine particulate matter","volume":"56","author":"Jedrychowski","year":"2010","journal-title":"Ann. Nutr. Metab."},{"key":"10.1016\/j.chemosphere.2020.126668_bib25","doi-asserted-by":"crossref","DOI":"10.1088\/1748-9326\/10\/7\/074005","article-title":"Ambient air pollution and congenital heart defects in Lanzhou, China","volume":"10","author":"Jin","year":"2015","journal-title":"Environ. Res. Lett."},{"key":"10.1016\/j.chemosphere.2020.126668_bib26","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1289\/ehp.9081","article-title":"Exposures to airborne particulate matter and adverse perinatal outcomes: a biologically plausible mechanistic framework for exploring potential effect modification by nutrition","volume":"114","author":"Kannan","year":"2006","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2020.126668_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envint.2016.11.012","article-title":"Exposure to traffic-related air pollution and risk of development of childhood asthma: a systematic review and meta-analysis","volume":"100","author":"Khreis","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.chemosphere.2020.126668_bib28","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/bs.ctdb.2015.12.010","article-title":"Gene-Environment interactions and the etiology of birth defects","volume":"116","author":"Krauss","year":"2016","journal-title":"Curr. Top. Dev. Biol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib29","doi-asserted-by":"crossref","first-page":"14035","DOI":"10.1073\/pnas.1210730109","article-title":"Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development","volume":"109","author":"Lage","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.chemosphere.2020.126668_bib30","doi-asserted-by":"crossref","first-page":"104953","DOI":"10.1016\/j.envint.2019.104953","article-title":"Spatial variations in ambient ultrafine particle concentrations and risk of congenital heart defects","volume":"130","author":"Lavigne","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.chemosphere.2020.126668_bib31","doi-asserted-by":"crossref","DOI":"10.1289\/EHP289","article-title":"Effects of prenatal PM10 exposure on fetal cardiovascular malformations in fuzhou, China: a retrospective case-control study","volume":"125","author":"Liu","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2020.126668_bib32","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1365-3016.2010.01096.x","article-title":"Differences in exposure assignment between conception and delivery: the impact of maternal mobility","volume":"24","author":"Lupo","year":"2010","journal-title":"Paediatr. Perinat. Epidemiol."},{"issue":"4","key":"10.1016\/j.chemosphere.2020.126668_bib64","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease","volume":"22","author":"Mantel","year":"1959","journal-title":"J.\u00a0Natl. Cancer Inst."},{"key":"10.1016\/j.chemosphere.2020.126668_bib33","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/s10565-010-9158-2","article-title":"Roles of oxidative stress in signaling and inflammation induced by particulate matter","volume":"26","author":"Mazzoli-Rocha","year":"2010","journal-title":"Cell Biol. Toxicol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher","year":"2009","journal-title":"PLoS Med."},{"key":"10.1016\/j.chemosphere.2020.126668_bib35","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1136\/oem.2007.035337","article-title":"From measures to models: an evaluation of air pollution exposure assessment for epidemiological studies of pregnant women","volume":"65","author":"Nethery","year":"2008","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.chemosphere.2020.126668_bib36","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph15102096","article-title":"Environmental contaminants and congenital heart defects: a Re-evaluation of the evidence","volume":"15","author":"Nicoll","year":"2018","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.chemosphere.2020.126668_bib38","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/ppe.12055","article-title":"Ambient air pollution and traffic exposures and congenital heart defects in the san Joaquin Valley of California","volume":"27","author":"Padula","year":"2013","journal-title":"Paediatr. Perinat. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib40","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.envres.2017.07.031","article-title":"Exposure to air pollution and noise from road traffic and risk of congenital anomalies in the Danish National Birth Cohort","volume":"159","author":"Pedersen","year":"2017","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib41","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1289\/ehp.1409546","article-title":"Elemental constituents of particulate matter and newborn\u2019s size in eight European cohorts","volume":"124","author":"Pedersen","year":"2016","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2020.126668_bib42","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1016\/j.envres.2009.08.011","article-title":"Increased micronuclei and bulky DNA adducts in cord blood after maternal exposures to traffic-related air pollution","volume":"109","author":"Pedersen","year":"2009","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib43","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1158\/1055-9965.EPI-04-0457","article-title":"DNA damage from polycyclic aromatic hydrocarbons measured by benzo[a]pyrene-DNA adducts in mothers and newborns from Northern Manhattan, the World Trade Center Area, Poland, and China","volume":"14","author":"Perera","year":"2005","journal-title":"Cancer Epidemiol. Biomark. Prev."},{"key":"10.1016\/j.chemosphere.2020.126668_bib44","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.envres.2008.11.007","article-title":"Maternal exposure to ambient air pollutants and risk of congenital anomalies","volume":"109","author":"Rankin","year":"2009","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.scitotenv.2018.02.181","article-title":"Maternal exposure to ambient PM10 during pregnancy increases the risk of congenital heart defects: evidence from machine learning models","volume":"630","author":"Ren","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2020.126668_bib46","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1136\/oem.2009.051201","article-title":"Air pollution and congenital anomalies","volume":"67","author":"Ritz","year":"2010","journal-title":"Occup. Environ. Med."},{"key":"10.1016\/j.chemosphere.2020.126668_bib47","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1093\/aje\/kwm181","article-title":"Ambient air pollution and preterm birth in the environment and pregnancy outcomes study at the University of California, Los Angeles","volume":"166","author":"Ritz","year":"2007","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib48","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/aje\/155.1.17","article-title":"Ambient air pollution and risk of birth defects in Southern California","volume":"155","author":"Ritz","year":"2002","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib49","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1289\/EHP38","article-title":"Lower placental leptin promoter methylation in association with fine particulate matter air pollution during pregnancy and placental nitrosative stress at birth in the ENVIRONAGE cohort","volume":"125","author":"Saenen","year":"2017","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2020.126668_bib50","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.ijheh.2018.07.008","article-title":"The association of air pollution with congenital anomalies: an exploratory study in the northern Netherlands","volume":"221","author":"Salavati","year":"2018","journal-title":"Int. J. Hyg Environ. Health"},{"key":"10.1016\/j.chemosphere.2020.126668_bib51","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1289\/ehp.1306802","article-title":"Traffic-related air pollution and congenital anomalies in Barcelona","volume":"122","author":"Schembari","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2020.126668_bib52","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/jes.2010.14","article-title":"The impact of daily mobility on exposure to traffic-related air pollution and health effect estimates","volume":"21","author":"Setton","year":"2011","journal-title":"J.\u00a0Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib53","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1093\/aje\/kwx139","article-title":"Maternal exposure to nitrogen dioxide, intake of methyl nutrients, and congenital heart defects in offspring","volume":"186","author":"Stingone","year":"2017","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib54","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1289\/ehp.1307289","article-title":"Maternal exposure to criteria air pollutants and congenital heart defects in offspring: results from the national birth defects prevention study","volume":"122","author":"Stingone","year":"2014","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2020.126668_bib55","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1093\/aje\/kwp011","article-title":"Ambient air pollution and cardiovascular malformations in Atlanta, Georgia, 1986-2003","volume":"169","author":"Strickland","year":"2009","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib56","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.envres.2015.07.006","article-title":"Associations between exposure to ambient benzene and PM(2.5) during pregnancy and the risk of selected birth defects in offspring","volume":"142","author":"Tanner","year":"2015","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib57","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.scitotenv.2015.09.051","article-title":"Does maternal exposure to benzene and PM10 during pregnancy increase the risk of congenital anomalies? A population-based case-control study","volume":"541","author":"Vinceti","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2020.126668_bib58","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1002\/bdra.23159","article-title":"Early prenatal exposure to air pollution and its associations with birth defects in a state-wide birth cohort from North Carolina. Birth defects research","volume":"97","author":"Vinikoor-Imler","year":"2013","journal-title":"Part A, Clinical and molecular teratology"},{"key":"10.1016\/j.chemosphere.2020.126668_bib59","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1289\/ehp.1002946","article-title":"Ambient air pollution and risk of congenital anomalies: a systematic review and meta-analysis","volume":"119","author":"Vrijheid","year":"2011","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2020.126668_bib60","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1161\/01.CIR.96.2.550","article-title":"Congenital heart defects: natural course and in utero development","volume":"96","author":"Yagel","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.chemosphere.2020.126668_bib61","doi-asserted-by":"crossref","first-page":"108817","DOI":"10.1016\/j.envres.2019.108817","article-title":"Ambient air pollution and diabetes: a systematic review and meta-analysis","volume":"180","author":"Yang","year":"2020","journal-title":"Environ. Res."},{"key":"10.1016\/j.chemosphere.2020.126668_bib62","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/jes.2016.1","article-title":"Maternal exposure to air pollutant PM2.5 and PM10 during pregnancy and risk of congenital heart defects","volume":"26","author":"Zhang","year":"2016","journal-title":"J.\u00a0Expo. Sci. Environ. Epidemiol."},{"key":"10.1016\/j.chemosphere.2020.126668_bib63","doi-asserted-by":"crossref","first-page":"34852","DOI":"10.1038\/srep34852","article-title":"Ozone and other air pollutants and the risk of congenital heart defects","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci. Rep."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653520308614?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653520308614?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T11:10:42Z","timestamp":1758625842000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653520308614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":62,"alternative-id":["S0045653520308614"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2020.126668","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Maternal air pollution exposure and congenital heart defects in offspring: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2020.126668","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"126668"}}