{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T20:05:50Z","timestamp":1792181150306,"version":"4.4.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100013239","name":"CESAM","doi-asserted-by":"publisher","award":["UIDP\/50017\/2020+UIDB\/50017\/2020"],"award-info":[{"award-number":["UIDP\/50017\/2020+UIDB\/50017\/2020"]}],"id":[{"id":"10.13039\/100013239","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013239","name":"CESAM","doi-asserted-by":"publisher","award":["IF\/00492 2013"],"award-info":[{"award-number":["IF\/00492 2013"]}],"id":[{"id":"10.13039\/100013239","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013239","name":"CESAM","doi-asserted-by":"publisher","award":["CEEC\/01304 2017"],"award-info":[{"award-number":["CEEC\/01304 2017"]}],"id":[{"id":"10.13039\/100013239","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.chemosphere.2020.127936","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T03:35:08Z","timestamp":1597289708000},"page":"127936","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["Selection of antibiotic resistance by metals in a riverine bacterial community"],"prefix":"10.1016","volume":"263","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2254-1636","authenticated-orcid":false,"given":"Isabel","family":"Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7965-4928","authenticated-orcid":false,"given":"Marta","family":"Tac\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7717-4939","authenticated-orcid":false,"given":"Isabel","family":"Henriques","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2020.127936_bib1","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.chemosphere.2019.01.147","article-title":"Long-term effects of oxytetracycline exposure in zebrafish: a multi-level perspective","volume":"222","author":"Almeida","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2020.127936_bib2","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.tim.2006.02.006","article-title":"Co-selection of antibiotic and metal resistance","volume":"14","author":"Baker-Austin","year":"2006","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib3","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.scitotenv.2015.05.102","article-title":"Assessment of copper and zinc salts as selectors of antibiotic resistance in Gram-negative bacteria","volume":"530\u2013531","author":"Becerra-Castro","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2020.127936_bib4","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1472-765X.2004.01650.x","article-title":"Copper amendment of agricultural soil selects for bacterial antibiotic resistance in the field","volume":"40","author":"Berg","year":"2005","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib5","doi-asserted-by":"crossref","first-page":"4481","DOI":"10.1128\/AEM.07878-11","article-title":"Simple absolute quantification method correcting for quantitative PCR efficiency variations for microbial community samples","volume":"78","author":"Brankatschk","year":"2012","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib6","doi-asserted-by":"crossref","first-page":"23390","DOI":"10.3390\/ijms161023390","article-title":"Heavy metal induced antibiotic resistance in bacterium LSJC7","volume":"16","author":"Chen","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.chemosphere.2020.127936_bib7","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1039\/C9EN00338J","article-title":"Impact of ZnO nanoparticles on the antibiotic resistance genes (ARGs) in estuarine water: ARG variations and their association with the microbial community","volume":"6","author":"Chen","year":"2019","journal-title":"Environ. Sci. Nano"},{"key":"10.1016\/j.chemosphere.2020.127936_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0191660","article-title":"High dietary zinc feeding promotes persistence of multi-resistant E. coli in the swine gut","volume":"13","author":"Ciesinski","year":"2018","journal-title":"PloS One"},{"key":"10.1016\/j.chemosphere.2020.127936_bib9","doi-asserted-by":"crossref","DOI":"10.1128\/CMR.00181-19","article-title":"Antimicrobial resistance in ESKAPE pathogens","volume":"33","author":"De Oliveira","year":"2020","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.chemosphere.2020.127936_bib10","doi-asserted-by":"crossref","DOI":"10.3390\/genes9080379","article-title":"Genomic and biotechnological characterization of the heavy-metal resistant, arsenic-oxidizing bacterium Ensifer sp. M14","volume":"9","author":"diCenzo","year":"2018","journal-title":"Genes"},{"key":"10.1016\/j.chemosphere.2020.127936_bib11","doi-asserted-by":"crossref","first-page":"25312","DOI":"10.1038\/srep25312","article-title":"Co-spread of metal and antibiotic resistance within ST3-IncHI2 plasmids from E.\u00a0coli isolates of food-producing animals","volume":"6","author":"Fang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.chemosphere.2020.127936_bib12","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.scitotenv.2017.04.196","article-title":"The impact of freshwater metal concentrations on the severity of histopathological changes in fish gills: a statistical perspective","volume":"599\u2013600","author":"Fonseca","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2020.127936_bib13","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01918-14","article-title":"Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals","volume":"5","author":"Gullberg","year":"2014","journal-title":"mBio"},{"key":"10.1016\/j.chemosphere.2020.127936_bib14","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002158","article-title":"Selection of resistant bacteria at very low antibiotic concentrations","volume":"7","author":"Gullberg","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.chemosphere.2020.127936_bib15","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.marpolbul.2016.05.031","article-title":"Co-selection of antibiotic and metal(loid) resistance in gram-negative epiphytic bacteria from contaminated salt marshes","volume":"109","author":"Henriques","year":"2016","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.chemosphere.2020.127936_bib16","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.femsec.2004.04.003","article-title":"Molecular sequence analysis of prokaryotic diversity in the middle and outer sections of the Portuguese estuary Ria de Aveiro","volume":"49","author":"Henriques","year":"2004","journal-title":"FEMS Microbiol. Ecol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib17","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1089\/mdr.2012.0029","article-title":"Prevalence and diversity of carbapenem-resistant bacteria in untreated drinking water in Portugal","volume":"18","author":"Henriques","year":"2012","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.chemosphere.2020.127936_bib18","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1099\/jmm.0.023036-0","article-title":"Bacterial antimicrobial metal ion resistance","volume":"64","author":"Hobman","year":"2015","journal-title":"J.\u00a0Med. Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.115880","article-title":"The role of the natural aquatic environment in the dissemination of extended spectrum beta-lactamase and carbapenemase encoding genes: a scoping review","author":"Hooban","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2020.127936_bib20","doi-asserted-by":"crossref","first-page":"3896","DOI":"10.1111\/1462-2920.13370","article-title":"Field-based evidence for copper contamination induced changes of antibiotic resistance in agricultural soils","volume":"18","author":"Hu","year":"2016","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib21","first-page":"916705","article-title":"Current status of trace metal pollution in soils affected by industrial activities","author":"Kabir","year":"2012","journal-title":"Sci. World J."},{"key":"10.1016\/j.chemosphere.2020.127936_bib22","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.scitotenv.2016.02.103","article-title":"Minimal selective concentrations of tetracycline in complex aquatic bacterial biofilms","volume":"553","author":"L undstr\u00f6m","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2020.127936_bib23","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1007\/s10661-015-4918-3","article-title":"Farmyard manures: the major agronomic sources of heavy metals in the philippi horticultural area in the western cape province of South Africa","volume":"187","author":"Malan","year":"2015","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.chemosphere.2020.127936_bib24","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.tim.2016.11.014","article-title":"Assessing the risk of antibiotic resistance transmission from the environment to humans: non-direct proportionality between abundance and risk","volume":"25","author":"Manaia","year":"2017","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2014.00419","article-title":"The contribution of Escherichia coli from human and animal sources to the integron gene pool in coastal waters","volume":"5","author":"Moura","year":"2014","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib26","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0168-6445(03)00048-2","article-title":"Efflux-mediated heavy metal resistance in prokaryotes","volume":"27","author":"Nies","year":"2003","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.chemosphere.2020.127936_bib27","article-title":"The environmental contribution to the dissemination of carbapenem and (fluoro)quinolone resistance genes by discharged and reused wastewater effluents: the role of cellular and extracellular DNA","volume":"116011","author":"Oliveira","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2020.127936_bib28","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/bs.ampbs.2017.02.001","article-title":"Metal resistance and its association with antibiotic resistance","volume":"70","author":"Pal","year":"2017","journal-title":"Adv. Microb. Physiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib29","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/j.tim.2017.04.010","article-title":"At the nexus of antibiotics and metals: the impact of Cu and Zn on antibiotic activity and resistance","volume":"25","author":"Poole","year":"2017","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib30","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1128\/AAC.45.3.837-844.2001","article-title":"Metallo-\u03b2-lactamase producers in environmental microbiota: new molecular class B enzyme in Janthinobacterium lividum","volume":"45","author":"Rossolini","year":"2001","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.chemosphere.2020.127936_bib31","doi-asserted-by":"crossref","first-page":"399","DOI":"10.3389\/fmicb.2012.00399","article-title":"Heavy metal driven co-selection of antibiotic resistance in soil and water bodies impacted by agriculture and aquaculture","volume":"3","author":"Seiler","year":"2012","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib32","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.scitotenv.2018.05.229","article-title":"Fate of cefotaxime-resistant Enterobacteriaceae and ESBL-producers over a full-scale wastewater treatment process with UV disinfection","volume":"639","author":"Silva","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2020.127936_bib33","doi-asserted-by":"crossref","first-page":"4134","DOI":"10.1128\/AEM.00359-12","article-title":"Resistance to broad-spectrum antibiotics in aquatic systems: anthropogenic activities modulate the dissemination of blaCTX-M-like genes","volume":"78","author":"Tac\u00e3o","year":"2012","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.chemosphere.2020.127936_bib34","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1089\/mdr.2015.0072","article-title":"Low prevalence of carbapenem-resistant bacteria in river water: resistance is mostly related to intrinsic mechanisms","volume":"21","author":"Tac\u00e3o","year":"2015","journal-title":"Microb. Drug Resist."},{"key":"10.1016\/j.chemosphere.2020.127936_bib35","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.marpolbul.2016.06.086","article-title":"Antibiotic and metal resistance in a ST395 Pseudomonas aeruginosa environmental isolate: a genomics approach","volume":"110","author":"Teixeira","year":"2016","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.chemosphere.2020.127936_bib36","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/sum.12545","article-title":"Co-selection for antibiotic resistance genes is induced in a soil amended with zinc","volume":"36","author":"Tongyi","year":"2020","journal-title":"Soil Use Manag."},{"key":"10.1016\/j.chemosphere.2020.127936_bib37","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/S1473-3099(14)70780-7","article-title":"Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data","volume":"14","author":"Van Boeckel","year":"2014","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.chemosphere.2020.127936_bib38","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.envpol.2018.06.047","article-title":"Environmental superbugs: the case study of Pedobacter spp","volume":"241","author":"Viana","year":"2018","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chemosphere.2020.127936_bib39","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.chemosphere.2016.12.027","article-title":"Distribution of tetracycline resistance genes and AmpC \u03b2-lactamase genes in representative non-urban sewage plants and correlations with treatment processes and heavy metals","volume":"170","author":"Xu","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2020.127936_bib40","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.envpol.2016.10.074","article-title":"Effect of the selective pressure of sub-lethal level of heavy metals on the fate and distribution of ARGs in the catchment scale","volume":"220","author":"Xu","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chemosphere.2020.127936_bib41","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.envint.2019.05.054","article-title":"Copper nanoparticles and copper ions promote horizontal transfer of plasmid-mediated multi-antibiotic resistance genes across bacterial genera","volume":"129","author":"Zhang","year":"2019","journal-title":"Environ. Int."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653520321317?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653520321317?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T14:14:41Z","timestamp":1731593681000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653520321317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":41,"alternative-id":["S0045653520321317"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2020.127936","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Selection of antibiotic resistance by metals in a riverine bacterial community","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2020.127936","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"127936"}}