{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T09:28:31Z","timestamp":1780478911100,"version":"3.54.1"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,6]],"date-time":"2023-07-06T00:00:00Z","timestamp":1688601600000},"content-version":"am","delay-in-days":582,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000084","name":"National Science Foundation Directorate for Engineering","doi-asserted-by":"publisher","award":["1804255"],"award-info":[{"award-number":["1804255"]}],"id":[{"id":"10.13039\/100000084","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000199","name":"US Department of Agriculture","doi-asserted-by":"publisher","award":["2017-69007-26309"],"award-info":[{"award-number":["2017-69007-26309"]}],"id":[{"id":"10.13039\/100000199","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005825","name":"National Institute of Food and Agriculture","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.chemosphere.2021.131408","type":"journal-article","created":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T05:27:32Z","timestamp":1625203652000},"page":"131408","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Evidence of low levels of trace organic contaminants in terminal lakes"],"prefix":"10.1016","volume":"285","author":[{"given":"Priyamvada","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6947-7611","authenticated-orcid":false,"given":"David","family":"Hanigan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2021.131408_bib1","series-title":"Collaboration for Environmental Evidence. Guidelines and Standards for Evidence Synthesis in Environmental Management","year":"2018"},{"issue":"9","key":"10.1016\/j.chemosphere.2021.131408_bib2","doi-asserted-by":"crossref","first-page":"2116","DOI":"10.1016\/j.chemosphere.2013.07.057","article-title":"Pharmaceuticals and personal care products found in the Great Lakes above concentrations of environmental concern","volume":"93","author":"Blair","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2021.131408_bib3","series-title":"Results of the Lake Michigan Mass Balance Study: Atrazine Data Report","author":"Brent","year":"2001"},{"key":"10.1016\/j.chemosphere.2021.131408_bib48","series-title":"Human-health Pharmaceutical Compounds in Lake Mead, Nevada and Arizona, and Las Vegas Wash, Nevada, October 2000-August 2001","author":"Boyd","year":"2002"},{"key":"10.1016\/j.chemosphere.2021.131408_bib4","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.watres.2017.12.044","article-title":"Spatial patterns of pharmaceuticals and wastewater tracers in the Hudson River Estuary","volume":"137","author":"Cantwell","year":"2018","journal-title":"Water Res."},{"issue":"3","key":"10.1016\/j.chemosphere.2021.131408_bib5","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1577\/1548-8659(1999)128<0507:EOHLOT>2.0.CO;2","article-title":"Effects of high levels of total dissolved solids in Walker Lake, Nevada, on survival and growth of Lahontan cutthroat trout","volume":"128","author":"Dickerson","year":"1999","journal-title":"Trans. Am. Fish. Soc."},{"key":"10.1016\/j.chemosphere.2021.131408_bib6","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.envpol.2015.01.002","article-title":"Effect of transpiration on plant accumulation and translocation of PPCP\/EDCs","volume":"198","author":"Dodgen","year":"2015","journal-title":"Environ. Pollut."},{"issue":"9","key":"10.1016\/j.chemosphere.2021.131408_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0182868","article-title":"Contaminants of emerging concern in tributaries to the Laurentian Great Lakes: I. Patterns of occurrence","volume":"12","author":"Elliott","year":"2017","journal-title":"PloS One"},{"key":"10.1016\/j.chemosphere.2021.131408_bib8","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.scitotenv.2013.04.024","article-title":"Detection of pharmaceuticals and personal care products (PPCPs) in near-shore habitats of southern Lake Michigan","volume":"458\u2013460","author":"Ferguson","year":"2013","journal-title":"Sci. Total Environ."},{"issue":"11","key":"10.1016\/j.chemosphere.2021.131408_bib9","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1002\/etc.3125","article-title":"Pharmaceuticals and other anthropogenic tracers in surface water: a randomized survey of 50 Minnesota lakes","volume":"34","author":"Ferrey","year":"2015","journal-title":"Environ. Toxicol. Chem."},{"key":"10.1016\/j.chemosphere.2021.131408_bib11","series-title":"Limnology of a Large, Deep, North American Terminal Lake, Pyramid Lake, Nevada","author":"Galat","year":"1981"},{"key":"10.1016\/j.chemosphere.2021.131408_bib12","series-title":"Bioaccumulation\u2013New Aspects and Developments","first-page":"1","article-title":"Bioaccumulation and occurrence of endocrine-disrupting chemicals (EDCs), persistent organic pollutants (POPs), and other organic compounds in fish and other organisms including humans","author":"Geyer","year":"2000"},{"issue":"10","key":"10.1016\/j.chemosphere.2021.131408_bib13","doi-asserted-by":"crossref","first-page":"5593","DOI":"10.1021\/es5008615","article-title":"Insights into the uptake processes of wastewater-borne pharmaceuticals by vegetables","volume":"48","author":"Goldstein","year":"2014","journal-title":"Environ. Sci. Technol."},{"issue":"1","key":"10.1016\/j.chemosphere.2021.131408_bib14","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1752-1688.2008.00289.x","article-title":"Occurrence of primidone, carbamazepine, caffeine, and precursors for N-nitrosodimethylamine in drinking water sources impacted by Wastewater1","volume":"45","author":"Guo","year":"2009","journal-title":"JAWRA J. Am. Water. Res. Ass."},{"key":"10.1016\/j.chemosphere.2021.131408_bib15","author":"Harzing"},{"issue":"5","key":"10.1016\/j.chemosphere.2021.131408_bib16","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1007\/s10841-013-9568-6","article-title":"Defining salinity limits on the survival and growth of benthic insects for the conservation management of saline Walker Lake, Nevada, USA","volume":"17","author":"Herbst","year":"2013","journal-title":"J. Insect Conserv."},{"key":"10.1016\/j.chemosphere.2021.131408_bib17","series-title":"Hydrological and Thermal Response of Lakes to Climate: Description and Modeling. Physics and Chemistry of Lakes","first-page":"63","author":"Hostetler","year":"1995"},{"issue":"1","key":"10.1016\/j.chemosphere.2021.131408_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ecolind.2007.06.002","article-title":"Veterinary antibiotics in the aquatic and terrestrial environment","volume":"8","author":"Kemper","year":"2008","journal-title":"Ecol. Indicat."},{"issue":"6","key":"10.1016\/j.chemosphere.2021.131408_bib19","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1021\/es011055j","article-title":"Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. Streams, 1999\u22122000: A national reconnaissance","volume":"36","author":"Kolpin","year":"2002","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2021.131408_bib20","volume":"vol. 34","author":"Larson","year":"2014"},{"key":"10.1016\/j.chemosphere.2021.131408_bib21","first-page":"14","article-title":"Chemicals of emerging concern in water and bottom sediment in the Great Lakes Basin, 2012\u2014collection methods, analytical methods, quality assurance, and study data","volume":"910","author":"Lee","year":"2015","journal-title":"U.S. Geological Survey Data Series"},{"issue":"8","key":"10.1016\/j.chemosphere.2021.131408_bib22","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1002\/etc.2281","article-title":"Quantification of pharmaceuticals, personal care products, and perfluoroalkyl substances in the marine sediments of Puget Sound, Washington, USA","volume":"32","author":"Long","year":"2013","journal-title":"Environ. Toxicol. Chem."},{"issue":"22","key":"10.1016\/j.chemosphere.2021.131408_bib23","doi-asserted-by":"crossref","first-page":"12961","DOI":"10.1021\/acs.est.9b02966","article-title":"An evidence synthesis of pharmaceuticals and personal care products (PPCPs) in the environment: imbalances among compounds, sewage treatment techniques, and ecosystem types","volume":"53","author":"Meyer","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2021.131408_bib25","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.watres.2016.10.045","article-title":"Perfluoroalkyl substances (PFASs) in wastewater treatment plants and drinking water treatment plants: removal efficiency and exposure risk","volume":"106","author":"Pan","year":"2016","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2021.131408_bib26","series-title":"R: A Language and Environment for Statistical Computing","year":"2019"},{"issue":"9","key":"10.1016\/j.chemosphere.2021.131408_bib27","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.marpolbul.2005.06.034","article-title":"Emerging chemicals of concern: pharmaceuticals and personal care products (PPCPs) in Asia, with particular reference to Southern China","volume":"50","author":"Richardson","year":"2005","journal-title":"Mar. Pollut. Bull."},{"key":"10.1016\/j.chemosphere.2021.131408_bib28","series-title":"The Salton Sea's Migratory Birds Mass-Mortality and Those Impacts along the Pacific Flyway","volume":"vol. 7","author":"Schrage","year":"2016"},{"issue":"6","key":"10.1016\/j.chemosphere.2021.131408_bib29","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1021\/es9022706","article-title":"Antidepressant pharmaceuticals in two U.S. Effluent-impacted streams: occurrence and fate in water and sediment, and selective uptake in fish neural tissue","volume":"44","author":"Schultz","year":"2010","journal-title":"Environ. Sci. Technol."},{"issue":"3","key":"10.1016\/j.chemosphere.2021.131408_bib30","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1080\/02755947.2012.675957","article-title":"Environmental and population strain effects on survival of lahontan cutthroat trout in walker lake, Nevada: a bayesian approach","volume":"32","author":"Sedinger","year":"2012","journal-title":"N. Am. J. Fish. Manag."},{"key":"10.1016\/j.chemosphere.2021.131408_bib31","doi-asserted-by":"crossref","first-page":"140698","DOI":"10.1016\/j.scitotenv.2020.140698","article-title":"Trace organic contaminants in field-scale cultivated alfalfa, soil, and pore water after 10 years of irrigation with reclaimed wastewater","volume":"744","author":"Sharma","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2021.131408_bib32","series-title":"Great Salt Lake Shorebirds, Their Habitats, and Food Base. Great Salt Lake Biology: A Terminal Lake in a Time of Change","first-page":"263","author":"Sorensen","year":"2020"},{"issue":"19","key":"10.1016\/j.chemosphere.2021.131408_bib33","doi-asserted-by":"crossref","first-page":"11649","DOI":"10.1021\/acs.est.5b02478","article-title":"Uptake and tissue distribution of pharmaceuticals and personal care products in wild fish from treated-wastewater-impacted streams","volume":"49","author":"Tanoue","year":"2015","journal-title":"Environ. Sci. Technol."},{"issue":"3","key":"10.1016\/j.chemosphere.2021.131408_bib34","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/S0380-1330(99)70754-9","article-title":"Predicted atrazine concentrations in the Great lakes: implications for biological effects","volume":"25","author":"Tierney","year":"1999","journal-title":"J. Great Lake. Res."},{"issue":"1","key":"10.1016\/j.chemosphere.2021.131408_bib35","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10750-005-1501-x","article-title":"Salt lakes in Australia: present problems and prognosis for the future","volume":"552","author":"Timms","year":"2005","journal-title":"Hydrobiologia"},{"key":"10.1016\/j.chemosphere.2021.131408_bib36","series-title":"Comparative tolerance of four stocks of cutthroat trout to extremes in temperature, salinity, and hypoxia","first-page":"434","author":"Wagner","year":"2001"},{"issue":"12","key":"10.1016\/j.chemosphere.2021.131408_bib37","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1038\/s41561-018-0265-7","article-title":"Recent global decline in endorheic basin water storages","volume":"11","author":"Wang","year":"2018","journal-title":"Nat. Geosci."},{"issue":"21","key":"10.1016\/j.chemosphere.2021.131408_bib38","doi-asserted-by":"crossref","first-page":"13759","DOI":"10.1021\/acs.est.0c04775","article-title":"Organic micropollutants in New York lakes: a statewide citizen science occurrence study","volume":"54","author":"Wang","year":"2020","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2021.131408_bib39","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.envpol.2017.08.032","article-title":"Occurrence, fate and transformation of emerging contaminants in water: an overarching review of the field","volume":"231","author":"Wilkinson","year":"2017","journal-title":"Environ. Pollut."},{"issue":"19","key":"10.1016\/j.chemosphere.2021.131408_bib40","doi-asserted-by":"crossref","first-page":"11286","DOI":"10.1021\/es502868k","article-title":"Treated wastewater irrigation: uptake of pharmaceutical and personal care products by common vegetables under field conditions","volume":"48","author":"Wu","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2021.131408_bib46","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/ngeo3052","article-title":"Decline of the World\u2019s Saline Lakes","volume":"10","author":"Wurtsbaugh","year":"2017","journal-title":"Nat. Geosci."},{"key":"10.1016\/j.chemosphere.2021.131408_bib41","doi-asserted-by":"crossref","first-page":"105306","DOI":"10.1016\/j.envint.2019.105306","article-title":"Anthropogenic impacts on the contamination of pharmaceuticals and personal care products (PPCPs) in the coastal environments of the Yellow and Bohai seas","volume":"135","author":"Yang","year":"2020","journal-title":"Environ. Int."},{"issue":"10","key":"10.1016\/j.chemosphere.2021.131408_bib42","doi-asserted-by":"crossref","first-page":"798","DOI":"10.3390\/w9100798","article-title":"Essentials of endorheic basins and lakes: a review in the context of current and future water resource management and mitigation activities in Central Asia","volume":"9","author":"Yapiyev","year":"2017","journal-title":"Water"},{"issue":"29","key":"10.1016\/j.chemosphere.2021.131408_bib43","doi-asserted-by":"crossref","first-page":"17228","DOI":"10.1039\/D0RA02019B","article-title":"Enhanced photodegradation of diphenhydramine in aqueous solution containing natural sand particles","volume":"10","author":"Yi","year":"2020","journal-title":"RSC Adv."},{"key":"10.1016\/j.chemosphere.2021.131408_bib44","series-title":"Origin and behavior of contamination of Lake neusiedl with PAH and PFAS","author":"Zessner","year":"2020"},{"issue":"6","key":"10.1016\/j.chemosphere.2021.131408_bib45","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.chemosphere.2006.06.067","article-title":"Simultaneous quantification of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and pharmaceuticals and personal care products (PPCPs) in Mississippi river water, in New Orleans, Louisiana, USA","volume":"66","author":"Zhang","year":"2007","journal-title":"Chemosphere"}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653521018804?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653521018804?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T02:34:26Z","timestamp":1762223666000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653521018804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":45,"alternative-id":["S0045653521018804"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2021.131408","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evidence of low levels of trace organic contaminants in terminal lakes","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2021.131408","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"131408"}}