{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T22:34:36Z","timestamp":1792449276056,"version":"4.5.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173491"],"award-info":[{"award-number":["82173491"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.chemosphere.2022.137460","type":"journal-article","created":{"date-parts":[[2022,12,3]],"date-time":"2022-12-03T04:29:26Z","timestamp":1670041766000},"page":"137460","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Expression level and function analysis of serum miRNAs in workers with occupational exposure to benzene series"],"prefix":"10.1016","volume":"313","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5694-1705","authenticated-orcid":false,"given":"Kai","family":"Dai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6819-2529","authenticated-orcid":false,"given":"Changfu","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2022.137460_bib1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3961\/jpmph.18.070","article-title":"Researches of epigenetic epidemiology for infections and radiation as carcinogen","volume":"51","author":"Bae","year":"2018","journal-title":"J Prev Med Public Health"},{"key":"10.1016\/j.chemosphere.2022.137460_bib2","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.yexmp.2014.04.011","article-title":"Aberrant miRNA profiles associated with chronic benzene poisoning","volume":"96","author":"Bai","year":"2014","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib3","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3233\/CBM-190899","article-title":"miR-638 in circulating leukaemia cells as a non-invasive biomarker in diagnosis, treatment response and MRD surveillance of acute promyelocytic leukaemia","volume":"29","author":"Bai","year":"2020","journal-title":"Cancer Biomarkers"},{"key":"10.1016\/j.chemosphere.2022.137460_bib4","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3324\/haematol.2020.267500","article-title":"Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways","volume":"107","author":"Braun","year":"2022","journal-title":"Haematologica"},{"key":"10.1016\/j.chemosphere.2022.137460_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.jri.2021.103305","article-title":"Ambient BTEX exposure and mid-pregnancy inflammatory biomarkers in pregnant African American women","volume":"145","author":"Cassidy-Bushrow","year":"2021","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib6","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s12033-022-00473-5","article-title":"MiR-221-3p facilitates thyroid cancer cell proliferation and inhibit apoptosis by targeting FOXP2 through hedgehog pathway","volume":"64","author":"Chang","year":"2022","journal-title":"Mol. Biotechnol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib7","doi-asserted-by":"crossref","first-page":"10552","DOI":"10.1007\/s11356-019-04492-9","article-title":"The hematologic effects of BTEX exposure among elderly residents in Nanjing: a cross-sectional study","volume":"26","author":"Chen","year":"2019","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.chemosphere.2022.137460_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.prp.2021.153351","article-title":"Dysregulation of miR-638 in the progression of cancers","volume":"220","author":"Chong","year":"2021","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.chemosphere.2022.137460_bib9","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.jmoldx.2020.01.016","article-title":"Polymer-based precipitation of extracellular vesicular miRNAs from serum improve gastric cancer miRNA biomarker performance","volume":"22","author":"Chung","year":"2020","journal-title":"J. Mol. Diagn."},{"key":"10.1016\/j.chemosphere.2022.137460_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2020.103518","article-title":"Effects of inhaled combined Benzene, Toluene, Ethylbenzene, and Xylenes (BTEX): toward an environmental exposure model","volume":"81","author":"Davidson","year":"2021","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib11","first-page":"6491","article-title":"miR-221-3p and miR-15b-5p promote cell proliferation and invasion by targeting Axin2 in liver cancer","volume":"18","author":"Dong","year":"2019","journal-title":"Oncol. Lett."},{"key":"10.1016\/j.chemosphere.2022.137460_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-03189-9","article-title":"Circulating microRNA-197-3p as a potential biomarker for asbestos exposure","volume":"11","author":"Frontini","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.chemosphere.2022.137460_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gene.2017.03.021","article-title":"The role of miRNA-223 in cancer: function, diagnosis and therapy","volume":"616","author":"Gao","year":"2017","journal-title":"Gene"},{"key":"10.1016\/j.chemosphere.2022.137460_bib14","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s12943-017-0583-1","article-title":"The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt\/\u03b2-catenin signaling","volume":"16","author":"Han","year":"2017","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.chemosphere.2022.137460_bib15","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.jaci.2013.06.036","article-title":"Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers","volume":"133","author":"Herberth","year":"2014","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib16","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/ilar.53.3-4.289","article-title":"Environmental epigenetics and its implication on disease risk and health outcomes","volume":"53","author":"Ho","year":"2012","journal-title":"ILAR J."},{"key":"10.1016\/j.chemosphere.2022.137460_bib17","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.leukres.2009.06.014","article-title":"Significant inverse correlation of microRNA-150\/MYB and microRNA-222\/p27 in myelodysplastic syndrome","volume":"34","author":"Hussein","year":"2010","journal-title":"Leuk. Res."},{"key":"10.1016\/j.chemosphere.2022.137460_bib18","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.jhep.2020.07.039","article-title":"MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinoma","volume":"74","author":"Komoll","year":"2021","journal-title":"J. Hepatol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib19","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.envpol.2019.03.086","article-title":"Occupational exposure to volatile organic compounds and health risks in Colorado nail salons","volume":"249","author":"Lamplugh","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chemosphere.2022.137460_bib20","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.2147\/OTT.S161586","article-title":"miR-342-3p suppresses hepatocellular carcinoma proliferation through inhibition of IGF-1R-mediated Warburg effect","volume":"11","author":"Liu","year":"2018","journal-title":"OncoTargets Ther."},{"key":"10.1016\/j.chemosphere.2022.137460_bib21","doi-asserted-by":"crossref","first-page":"403","DOI":"10.21037\/jtd.2016.02.56","article-title":"Analysis of plasma microRNA expression profiles in a Chinese population occupationally exposed to benzene and in a population with chronic benzene poisoning","volume":"8","author":"Liu","year":"2016","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.chemosphere.2022.137460_bib22","doi-asserted-by":"crossref","first-page":"403","DOI":"10.21037\/jtd.2016.02.56","article-title":"Analysis of plasma microRNA expression profiles in a Chinese population occupationally exposed to benzene and in a population with chronic benzene poisoning","volume":"8","author":"Liu","year":"2016","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.chemosphere.2022.137460_bib23","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1016\/j.chemosphere.2012.08.012","article-title":"Application of micronucleus test and comet assay to evaluate BTEX biodegradation","volume":"90","author":"Mazzeo","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2022.137460_bib24","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.mce.2011.09.014","article-title":"The epigenome as a target for heritable environmental disruptions of cellular function","volume":"354","author":"McCarrey","year":"2012","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib25","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/s41698-018-0057-y","article-title":"Tobacco biomarkers and genetic\/epigenetic analysis to investigate ethnic\/racial differences in lung cancer risk among smokers","volume":"2","author":"Murphy","year":"2018","journal-title":"NPJ Precis Oncol"},{"key":"10.1016\/j.chemosphere.2022.137460_bib26","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.pathol.2020.03.010","article-title":"The effect of miR-223 on cellular behaviour in non-5q myelodysplastic syndromes through targeting RPS14","volume":"52","author":"Nie","year":"2020","journal-title":"Pathology"},{"key":"10.1016\/j.chemosphere.2022.137460_bib27","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3389\/fgene.2012.00043","article-title":"Understanding alcoholism through microRNA signatures in brains of human alcoholics","volume":"3","author":"Nunez","year":"2012","journal-title":"Front. Genet."},{"key":"10.1016\/j.chemosphere.2022.137460_bib28","doi-asserted-by":"crossref","DOI":"10.2174\/1570163817999201117114237","article-title":"Micro-RNA (miRNA): a biomarker to identify novel compounds in drug discovery and delivery for cancer therapy","volume":"18","author":"Paramasivam","year":"2021","journal-title":"Curr. Drug Discov. Technol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib29","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.3109\/10428190903147645","article-title":"Hematopoiesis-related microRNA expression in myelodysplastic syndromes","volume":"50","author":"Pons","year":"2009","journal-title":"Leuk. Lymphoma"},{"key":"10.1016\/j.chemosphere.2022.137460_bib30","doi-asserted-by":"crossref","DOI":"10.3390\/biology10080793","article-title":"Cigarette smoking alters the expression of circulating microRNAs and its potential diagnostic value in female lung cancer patients","volume":"10","author":"Ram\u00edrez-Salazar","year":"2021","journal-title":"Biology"},{"key":"10.1016\/j.chemosphere.2022.137460_bib31","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1186\/s12967-019-2114-x","article-title":"Circulating microRNAs as minimal residual disease biomarkers in childhood acute lymphoblastic leukemia","volume":"17","author":"Rzepiel","year":"2019","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.chemosphere.2022.137460_bib32","doi-asserted-by":"crossref","first-page":"160","DOI":"10.21037\/tcr.2019.01.18","article-title":"Characterization of microRNA expression profiles by deep sequencing of small RNA libraries in leukemia patients from Naxi ethnic","volume":"8","author":"Shen","year":"2019","journal-title":"Transl. Cancer Res."},{"key":"10.1016\/j.chemosphere.2022.137460_bib33","doi-asserted-by":"crossref","first-page":"518","DOI":"10.3923\/pjbs.2020.518.525","article-title":"Hypermethylation in gene promoters are induced by chronic exposure to benzene, toluene, ethylbenzene and xylenes","volume":"23","author":"Silvestre","year":"2020","journal-title":"Pakistan J. Biol. Sci."},{"key":"10.1016\/j.chemosphere.2022.137460_bib34","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.toxrep.2020.05.006","article-title":"Occupational exposure to volatile organic compounds affects microRNA profiling: towards the identification of novel biomarkers","volume":"7","author":"Sisto","year":"2020","journal-title":"Toxicol Rep"},{"key":"10.1016\/j.chemosphere.2022.137460_bib35","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.toxrep.2019.01.001","article-title":"Circulating microRNAs as potential biomarkers of occupational exposure to low dose organic solvents","volume":"6","author":"Sisto","year":"2019","journal-title":"Toxicol Rep"},{"key":"10.1016\/j.chemosphere.2022.137460_bib36","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1016\/j.ijheh.2015.06.002","article-title":"Blood miRNAs as sensitive and specific biological indicators of environmental and occupational exposure to volatile organic compound (VOC)","volume":"218","author":"Song","year":"2015","journal-title":"Int. J. Hyg Environ. Health"},{"key":"10.1016\/j.chemosphere.2022.137460_bib37","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-68296-5","article-title":"Circulating miRNAs as molecular markers of occupational grain dust exposure","volume":"10","author":"Straumfors","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.chemosphere.2022.137460_bib38","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1080\/19338244.2020.1747966","article-title":"MicroRNAs diagnostic and prognostic value as predictive markers for malignant mesothelioma","volume":"75","author":"Sturchio","year":"2020","journal-title":"Arch. Environ. Occup. Health"},{"key":"10.1016\/j.chemosphere.2022.137460_bib39","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.3389\/fimmu.2019.01525","article-title":"The role of epigenetics in autoimmune\/inflammatory disease","volume":"10","author":"Surace","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.chemosphere.2022.137460_bib40","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.gene.2016.06.035","article-title":"miR-197: a novel biomarker for cancers","volume":"591","author":"Wang","year":"2016","journal-title":"Gene"},{"key":"10.1016\/j.chemosphere.2022.137460_bib41","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/1759-7714.14284","article-title":"miR-223-3p targets FBXW7 to promote epithelial-mesenchymal transition and metastasis in breast cancer","volume":"13","author":"Wang","year":"2022","journal-title":"Thorac Cancer"},{"key":"10.1016\/j.chemosphere.2022.137460_bib42","doi-asserted-by":"crossref","first-page":"27058","DOI":"10.3390\/ijms161126001","article-title":"Benzene-induced aberrant miRNA expression profile in hematopoietic progenitor cells in C57bl\/6 mice","volume":"16","author":"Wei","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.chemosphere.2022.137460_bib43","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1667\/RR14702.1","article-title":"Serum microRNAs as early indicators for estimation of exposure degree in response to ionizing irradiation","volume":"188","author":"Wei","year":"2017","journal-title":"Radiat. Res."},{"key":"10.1016\/j.chemosphere.2022.137460_bib44","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1161\/CIRCRESAHA.111.300539","article-title":"Circulating microRNAs as novel biomarkers for platelet activation","volume":"112","author":"Willeit","year":"2013","journal-title":"Circ. Res."},{"key":"10.1016\/j.chemosphere.2022.137460_bib45","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph13121212","article-title":"Oxidative stress and genotoxicity of long-term occupational exposure to low levels of BTEX in gas station workers","volume":"13","author":"Xiong","year":"2016","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.chemosphere.2022.137460_bib46","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.molcel.2011.07.024","article-title":"Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants","volume":"43","author":"Yang","year":"2011","journal-title":"Mol. Cell"},{"key":"10.1016\/j.chemosphere.2022.137460_bib47","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1080\/21655979.2021.2006974","article-title":"MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN\/AKT pathway","volume":"13","author":"Zhai","year":"2022","journal-title":"Bioengineered"},{"key":"10.1016\/j.chemosphere.2022.137460_bib48","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.jes.2021.01.035","article-title":"Characteristics, sources and health risks assessment of VOCs in Zhengzhou, China during haze pollution season","volume":"108","author":"Zhang","year":"2021","journal-title":"J. Environ. Sci. (China)"},{"key":"10.1016\/j.chemosphere.2022.137460_bib49","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/s13148-020-00926-1","article-title":"Epigenetic silencing of miR-342-3p in B cell lymphoma and its impact on autophagy","volume":"12","author":"Zhang","year":"2020","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.chemosphere.2022.137460_bib50","doi-asserted-by":"crossref","first-page":"425","DOI":"10.3233\/CH-200906","article-title":"Silencing of long noncoding RNA TUG1 inhibits viability and promotes apoptosis of acute myeloid leukemia cells by targeting microRNA-221-3p\/KIT axis","volume":"76","author":"Zhang","year":"2020","journal-title":"Clin. Hemorheol. Microcirc."},{"key":"10.1016\/j.chemosphere.2022.137460_bib51","article-title":"Circular RNA protein tyrosine kinase 2 promotes cell proliferation, migration and suppresses apoptosis via activating MicroRNA-638 mediated MEK\/ERK, WNT\/\u03b2-Catenin signaling pathways in multiple myeloma","volume":"11","author":"Zhou","year":"2021","journal-title":"Front. Oncol."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653522039534?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653522039534?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T16:14:31Z","timestamp":1736352871000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653522039534"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":51,"alternative-id":["S0045653522039534"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2022.137460","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression level and function analysis of serum miRNAs in workers with occupational exposure to benzene series","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2022.137460","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"137460"}}