{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:51:39Z","timestamp":1792162299263,"version":"4.4.0"},"reference-count":43,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100007771","name":"\u015al\u0105ski Uniwersytet Medyczny","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007771","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010252","name":"Medical University of Silesia","doi-asserted-by":"publisher","award":["PCN-1-030\/N\/2\/F"],"award-info":[{"award-number":["PCN-1-030\/N\/2\/F"]}],"id":[{"id":"10.13039\/501100010252","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010252","name":"Medical University of Silesia","doi-asserted-by":"publisher","award":["PCN-1-035\/N\/2\/F"],"award-info":[{"award-number":["PCN-1-035\/N\/2\/F"]}],"id":[{"id":"10.13039\/501100010252","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.chemosphere.2023.139854","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T23:23:51Z","timestamp":1692660231000},"page":"139854","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Degradation of veterinary antibiotics by Fenton process: Products identification and toxicity assessment"],"prefix":"10.1016","volume":"341","author":[{"given":"Wojciech","family":"Baran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8996-8311","authenticated-orcid":false,"given":"Ewa","family":"Adamek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2023.139854_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psep.2016.06.015","article-title":"Photocatalytic degradation of veterinary antibiotics: biodegradability and antimicrobial activity of intermediates","volume":"103","author":"Adamek","year":"2016","journal-title":"Process Saf. Environ."},{"key":"10.1016\/j.chemosphere.2023.139854_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232415676","article-title":"Degradation of the selected antibiotic in an aqueous solution by the fenton process: kinetics, products and ecotoxicity","volume":"23","author":"Adamek","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.chemosphere.2023.139854_bib3","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/177433a0","article-title":"Avidity of the tetracyclines for the cations of metals","volume":"177","author":"Albert","year":"1956","journal-title":"Nature"},{"key":"10.1016\/j.chemosphere.2023.139854_bib4","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.chemosphere.2017.11.165","article-title":"Removal of veterinary antibiotics from wastewater by electrocoagulation","volume":"194","author":"Baran","year":"2018","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2023.139854_bib5","doi-asserted-by":"crossref","first-page":"4392","DOI":"10.1016\/j.watres.2009.06.057","article-title":"Removal of veterinary antibiotics from sequencing batch reactor (SBR) pretreated swine wastewater by Fenton's reagent","volume":"43","author":"Ben","year":"2009","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2023.139854_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.153102","article-title":"Progress of homogeneous and heterogeneous electro-Fenton treatments of antibiotics in synthetic and real wastewaters. A critical review on the period 2017\u20132021","volume":"819","author":"Brillas","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2023.139854_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2021.113435","article-title":"Development of reactive iron-coated natural filter media for treating antibiotic residual in swine wastewater: mechanisms, intermediates and toxicity","volume":"298","author":"Changduang","year":"2021","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.chemosphere.2023.139854_bib8","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1128\/MMBR.65.2.232-260.2001","article-title":"Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance","volume":"65","author":"Chopra","year":"2001","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.chemosphere.2023.139854_bib9","author":"Coelho"},{"key":"10.1016\/j.chemosphere.2023.139854_bib11","series-title":"Sales of Veterinary Antimicrobial Agents in 31 European Countries in 2019 and 2020","year":"2021"},{"key":"10.1016\/j.chemosphere.2023.139854_bib12","series-title":"European Surveillance of Veterinary Antimicrobial Consumption (ESVAC)","year":"2023"},{"key":"10.1016\/j.chemosphere.2023.139854_bib14","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.7164\/antibiotics.49.1044","article-title":"Structure-activity studies of tylosin-related macrolides","volume":"49","author":"Fish","year":"1996","journal-title":"J. Antibiot. (Tokyo)"},{"key":"10.1016\/j.chemosphere.2023.139854_bib15","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.jhazmat.2007.04.055","article-title":"Sulfamethoxazole abatement by photo-Fenton: toxicity, inhibition and biodegradability assessment of intermediates","volume":"146","author":"Gonz\u00e1lez","year":"2007","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.chemosphere.2023.139854_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2020.115514","article-title":"Oxidation of tetracycline and oxytetracycline for the photo-Fenton process: their transformation products and toxicity assessment","volume":"172","author":"Han","year":"2020","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2023.139854_bib17","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1016\/S0140-6736(18)30110-7","article-title":"Superbugs and us","volume":"391","author":"Honigsbaum","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.chemosphere.2023.139854_bib18","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.jphotobiol.2018.05.022","article-title":"Degradation of macrolide antibiotics via sono or photo coupled with Fenton methods in the presence of ZnS quantum dots decorated SnO2 nanosheets","volume":"185","author":"Hosseini","year":"2018","journal-title":"J. Photochem. Photobiol., B"},{"key":"10.1016\/j.chemosphere.2023.139854_bib19","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1186\/s12917-018-1645-3","article-title":"Pharmacokinetic-pharmacodynamic modeling of tylosin against Streptococcus suis in pigs","volume":"14","author":"Huang","year":"2018","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.chemosphere.2023.139854_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.jwpe.2020.101886","article-title":"A review of methods for the removal of penicillins from water","volume":"39","author":"Ighalo","year":"2021","journal-title":"J. Water Process Eng."},{"key":"10.1016\/j.chemosphere.2023.139854_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.113464","article-title":"Recent progress in Fenton\/Fenton-like reactions for the removal of antibiotics in aqueous environments","volume":"236","author":"Jiang","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.chemosphere.2023.139854_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ecolind.2007.06.002","article-title":"Veterinary antibiotics in the aquatic and terrestrial environment","volume":"8","author":"Kemper","year":"2008","journal-title":"Ecol. Indicat."},{"key":"10.1016\/j.chemosphere.2023.139854_bib23","doi-asserted-by":"crossref","first-page":"180","DOI":"10.3390\/microorganisms7060180","article-title":"Antibiotic pollution in the environment: from microbial ecology to public policy","volume":"7","author":"Kraemer","year":"2019","journal-title":"Microorganisms"},{"key":"10.1016\/j.chemosphere.2023.139854_bib24","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1002\/rcm.6970","article-title":"Structural elucidation of stress degradation products of ampicillin sodium by liquid chromatography\/hybrid triple quadrupole linear ion trap mass spectrometry and liquid chromatography\/hybrid quadrupole time-of-flight mass spectrometry","volume":"28","author":"Li","year":"2014","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.chemosphere.2023.139854_bib25","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.jphotochem.2018.04.014","article-title":"Individual and simultaneous degradation of the antibiotics sulfamethoxazole and trimethoprim in aqueous solutions by Fenton, Fenton-like and photo-Fenton processes using solar and UV radiations","volume":"360","author":"Mart\u00ednez-Costa","year":"2018","journal-title":"J. Photochem. Photobiol. A-Chem."},{"key":"10.1016\/j.chemosphere.2023.139854_bib26","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.watres.2012.11.027","article-title":"Urban wastewater treatment plants as hotspots for the release of antibiotics in the environment: a review","volume":"47","author":"Michael","year":"2013","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2023.139854_bib27","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.apcatb.2018.12.030","article-title":"Solar photo-Fenton oxidation followed by adsorption on activated carbon for the minimisation of antibiotic resistance determinants and toxicity present in urban wastewater","volume":"244","author":"Michael","year":"2019","journal-title":"Appl. Catal. B Environ."},{"key":"10.1016\/j.chemosphere.2023.139854_bib28","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.chemosphere.2017.02.019","article-title":"Removal of pharmaceuticals from water by homo\/heterogonous Fenton-type processes \u2013 a review","volume":"174","author":"Mirzaei","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2023.139854_bib29","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.chemosphere.2014.08.050","article-title":"Hydrolysis of amphenicol and macrolide antibiotics: chloramphenicol, florfenicol, spiramycin, and tylosin","volume":"134","author":"Mitchell","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2023.139854_bib30","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.cej.2017.09.057","article-title":"Comparing VUV and VUV\/Fe2+ processes for decomposition of cloxacillin antibiotic: degradation rate and pathways, mineralization and by-product analysis","volume":"332","author":"Moussavi","year":"2018","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.chemosphere.2023.139854_bib31","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.psep.2019.02.031","article-title":"Visible light degradation of macrolide antibiotic azithromycin by novel ZrO2\/Ag@TiO2 nanorod composite: transformation pathways and toxicity evaluation","volume":"125","author":"Naraginti","year":"2019","journal-title":"Process Saf. Environ."},{"key":"10.1016\/j.chemosphere.2023.139854_bib32","doi-asserted-by":"crossref","DOI":"10.15386\/mpr-1742","article-title":"Antibiotics in the environment: causes and consequences","author":"Polianciuc","year":"2020","journal-title":"Med. Pharm. Rep"},{"key":"10.1016\/j.chemosphere.2023.139854_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.envpol.2016.12.017","article-title":"Tetracyclines metal complexation: significance and fate of mutual existence in the environment","volume":"221","author":"Pulicharla","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chemosphere.2023.139854_bib34","doi-asserted-by":"crossref","first-page":"157","DOI":"10.3390\/antibiotics8040157","article-title":"Actinomycete-derived polyketides as a source of antibiotics and lead structures for the development of new antimicrobial drugs","volume":"8","author":"Robertsen","year":"2019","journal-title":"Antibiotics"},{"key":"10.1016\/j.chemosphere.2023.139854_bib35","doi-asserted-by":"crossref","first-page":"655","DOI":"10.3390\/toxics10110655","article-title":"Influence of pH on the kinetics and products of photocatalytic degradation of sulfonamides in aqueous solutions","volume":"10","author":"Sapi\u0144ska","year":"2022","journal-title":"Toxics"},{"key":"10.1016\/j.chemosphere.2023.139854_bib36","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1080\/07388551.2018.1471038","article-title":"Research progress on distribution, migration, transformation of antibiotics and antibiotic resistance genes (ARGs) in aquatic environment","volume":"38","author":"Shao","year":"2018","journal-title":"Crit. Rev. Biotechnol."},{"key":"10.1016\/j.chemosphere.2023.139854_bib37","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.biortech.2017.08.150","article-title":"Anaerobic treatment of pharmaceutical wastewater: a critical review","volume":"245","author":"Shi","year":"2017","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.chemosphere.2023.139854_bib38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/plasma1010001","article-title":"Mechanism of ampicillin degradation by non-thermal plasma treatment with Fe-DBD","volume":"1","author":"Smith","year":"2017","journal-title":"Plasma"},{"key":"10.1016\/j.chemosphere.2023.139854_bib39","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.chemosphere.2010.12.025","article-title":"Photodegradation of azithromycin in various aqueous systems under simulated and natural solar radiation: kinetics and identification of photoproducts","volume":"83","author":"Tong","year":"2011","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2023.139854_bib40","doi-asserted-by":"crossref","first-page":"3922","DOI":"10.1016\/j.watres.2009.04.006","article-title":"Degradation of sulfamethoxazole in water by solar photo-Fenton. Chemical and toxicological evaluation","volume":"43","author":"Trov\u00f3","year":"2009","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2023.139854_bib41","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1039\/b704059h","article-title":"Intra-laboratory evaluation of microbial assay for risk assessment (MARA) for potential application in the implementation of the water framework directive (WFD)","volume":"9","author":"Wadhia","year":"2007","journal-title":"J. Environ. Monit."},{"key":"10.1016\/j.chemosphere.2023.139854_bib42","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1016\/j.wasman.2014.08.001","article-title":"Validation of Microtox as a first screening tool for waste classification","volume":"34","author":"Weltens","year":"2014","journal-title":"Waste Manage. (Tucson, Ariz.)"},{"key":"10.1016\/j.chemosphere.2023.139854_bib43","first-page":"1","article-title":"Identification of the related substances in ampicillin capsule by rapid resolution liquid chromatography coupled with electrospray ionization tandem mass spectrometry","author":"Zhang","year":"2014","journal-title":"J. Anal. Methods Chem."},{"key":"10.1016\/j.chemosphere.2023.139854_bib44","article-title":"Efficient photoelectrocatalytic degradation of tylosin on TiO2 nanotube arrays with tunable phosphorus dopants","volume":"9","author":"Zhang","year":"2021","journal-title":"J. Environ. Chem. Eng."},{"key":"10.1016\/j.chemosphere.2023.139854_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2020.125021","article-title":"Effect of low-level H2O2 and Fe(II) on the UV treatment of tetracycline antibiotics and the toxicity of reaction solutions to zebrafish embryos","volume":"394","author":"Zhao","year":"2020","journal-title":"Chem. Eng. J."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653523021239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653523021239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:06:40Z","timestamp":1758632800000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653523021239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":43,"alternative-id":["S0045653523021239"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2023.139854","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Degradation of veterinary antibiotics by Fenton process: Products identification and toxicity assessment","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2023.139854","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"139854"}}