{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T10:59:45Z","timestamp":1785495585667,"version":"3.56.0"},"reference-count":52,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100024370","name":"Governo Italiano Ministero dell'Istruzione dell'Universita e della Ricerca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100024370","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.chemosphere.2023.140739","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T23:55:30Z","timestamp":1700610930000},"page":"140739","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["The environmental pollutant BDE-47 modulates immune responses in in vitro and in vivo murine models"],"prefix":"10.1016","volume":"349","author":[{"given":"Bianca","family":"Barletta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Corinti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Maranghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8029-8625","authenticated-orcid":false,"given":"Sabrina","family":"Tait","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Tassinari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Martinelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2375-5698","authenticated-orcid":false,"given":"Alessandra","family":"Longo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8328-0698","authenticated-orcid":false,"given":"Valeria","family":"Longo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Colombo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7387-9683","authenticated-orcid":false,"given":"Gabriella","family":"Di Felice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cinzia","family":"Butteroni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2023.140739_bib1","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1002\/hep.30766","article-title":"Dysregulated autophagy and lysosome function are linked to exosome production by micro-RNA 155 in alcoholic liver disease","volume":"70","author":"Babuta","year":"2019","journal-title":"Hepatology"},{"key":"10.1016\/j.chemosphere.2023.140739_bib2","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/498232","article-title":"MicroRNA signature in alcoholic liver disease","author":"Bala","year":"2012","journal-title":"Int J Hepatol"},{"key":"10.1016\/j.chemosphere.2023.140739_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232214465","article-title":"BDE-47, -99, -209 and their ternary mixture disrupt glucose and lipid metabolism of Hepg2 cells at dietary relevant concentrations: mechanistic insight through integrated transcriptomics and proteomics analysis","volume":"23","author":"Casella","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.chemosphere.2023.140739_bib4","article-title":"2, 2', 4, 4'-tetrabromobisphenol ether (BDE-47) induces mitochondrial dysfunction and related liver injury via eliciting miR-34a-5p-mediated mitophagy impairment","volume":"258","author":"Chen","year":"2019","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.chemosphere.2023.140739_bib5","first-page":"172","article-title":"Polybrominated diphenyl ether (PBDE) flame retardants: environmental contamination, human body burden and potential adverse health effects","volume":"79","author":"Costa","year":"2008","journal-title":"Acta Biomed."},{"key":"10.1016\/j.chemosphere.2023.140739_bib6","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1159\/000444586","article-title":"Serum levels of polybrominated diphenyl ethers in girls with premature thelarche","volume":"86","author":"Deodati","year":"2016","journal-title":"Horm. Res. Paediatr."},{"key":"10.1016\/j.chemosphere.2023.140739_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.129872","article-title":"DBDPE and ZnO NPs synergistically induce neurotoxicity of SK-N-SH cells and activate mitochondrial apoptosis signaling pathway and Nrf2-mediated antioxidant pathway","volume":"441","author":"Dong","year":"2023","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.chemosphere.2023.140739_bib8","first-page":"2156","article-title":"Scientific opinion on polybrominated diphenyl ethers (PBDEs) in food","volume":"9","year":"2011","journal-title":"EFSA J."},{"key":"10.1016\/j.chemosphere.2023.140739_bib9","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1093\/toxsci\/kfs098","article-title":"Effects of chronic exposure to an environmentally relevant mixture of brominated flame retardants on the reproductive and thyroid system in adult male rats","volume":"127","author":"Ernest","year":"2012","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.chemosphere.2023.140739_bib10","first-page":"33","article-title":"Regulation (EU) 2019\/1021 of the European Parliament and of the Council of 20 June 2019 on persistent organic pollutants (recast)","volume":"169","year":"2019","journal-title":"Off. J. Eur. Union"},{"key":"10.1016\/j.chemosphere.2023.140739_bib11","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3109\/1547691X.2011.643418","article-title":"Immune function in female B(6)C(3)F(1) mice is modulated by DE-71, a commercial polybrominated diphenyl ether mixture","volume":"9","author":"Fair","year":"2012","journal-title":"J. Immunot."},{"key":"10.1016\/j.chemosphere.2023.140739_bib12","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2021.12353","article-title":"Functional role of miR-155 in physiological and pathological processes of liver injury","volume":"24","author":"Feng","year":"2021","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.chemosphere.2023.140739_bib13","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1002\/jat.3270","article-title":"Long-term exposure to high levels of decabrominated diphenyl ether inhibits CD4 T-cell functions in C57Bl\/6 mice","volume":"36","author":"Feng","year":"2016","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0300-483X(94)90052-3","article-title":"Immunologic and endocrine effects of the flame-retardant pentabromodiphenyl ether (DE-71) in C57BL\/6J mice","volume":"86","author":"Fowles","year":"1994","journal-title":"Toxicology"},{"key":"10.1016\/j.chemosphere.2023.140739_bib15","article-title":"BDE-47 induces immunotoxicity in RAW264.7 macrophages through the reactive oxygen species-mediated mitochondrial apoptotic pathway","volume":"28","author":"Gao","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.chemosphere.2023.140739_bib16","doi-asserted-by":"crossref","first-page":"7368","DOI":"10.3390\/ijms21197368","article-title":"Identifying differentially expressed MicroRNAs, target genes, and key pathways deregulated in patients with liver diseases","volume":"21","author":"Gholizadeh","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.chemosphere.2023.140739_bib17","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.3390\/ijerph15091834","article-title":"The role of polybrominated diphenyl ethers in thyroid carcinogenesis: is it a weak hypothesis or a hidden reality? From facts to new perspectives","volume":"15","author":"Gorini","year":"2018","journal-title":"Int. J. Environ. Res. Publ. Health"},{"key":"10.1016\/j.chemosphere.2023.140739_bib18","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1080\/15476910701337308","article-title":"Immunotoxicity evaluation by immune function tests: focus on the T-dependent antibody response (TDAR) [overview of a workshop session at the 45th annual meeting of the society of toxicology (SOT) March 5-9, 2006 San Diego, CA]","volume":"4","author":"Herzyk","year":"2007","journal-title":"J. Immunot."},{"key":"10.1016\/j.chemosphere.2023.140739_bib19","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1021\/es035082g","article-title":"Polybrominated diphenyl ethers in the environment and in people: a meta-analysis of concentrations","volume":"38","author":"Hites","year":"2004","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib20","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/7437281","article-title":"miR-155: an important role in inflammation response","volume":"2022","author":"Hu","year":"2022","journal-title":"J Immunol Res"},{"key":"10.1016\/j.chemosphere.2023.140739_bib21","doi-asserted-by":"crossref","first-page":"5177","DOI":"10.1021\/es050399x","article-title":"Polybrominated diphenyl ethers and polychlorinated biphenyls in human adipose tissue from New York","volume":"39","author":"Johnson-Restrepo","year":"2005","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib22","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2022.904607","article-title":"Low-dose exposure to PBDE disrupts genomic integrity and innate immunity in mammary tissue","volume":"13","author":"Lamkin","year":"2022","journal-title":"Front. Genet."},{"key":"10.1016\/j.chemosphere.2023.140739_bib23","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.yrtph.2014.02.008","article-title":"The T-cell-dependent antibody response assay in nonclinical studies of pharmaceuticals and chemicals: study design, data analysis, interpretation","volume":"69","author":"Lebrec","year":"2014","journal-title":"Regul. Toxicol. Pharmacol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib24","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/j.chemosphere.2018.12.082","article-title":"In vitro exposure to 2,2',4,4'-tetrabromobisphenol ether (PBDE-47) impairs innate inflammatory response","volume":"219","author":"Longo","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2023.140739_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.664534","article-title":"2,2'4,4'-Tetrabromodiphenyl ether (PBDE-47) modulates the intracellular miRNA profile, sEV biogenesis and their miRNA cargo exacerbating the LPS-induced pro-inflammatory response in THP-1 macrophages","volume":"12","author":"Longo","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib26","article-title":"Impact of the flame retardant 2,2'4,4'-tetrabromobisphenol ether (PBDE-47) in THP-1 macrophage-like cell function via small extracellular vesicles","volume":"13","author":"Longo","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib27","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.chemosphere.2014.08.029","article-title":"In vitro immune toxicity of polybrominated diphenyl ethers on murine peritoneal macrophages: apoptosis and immune cell dysfunction","volume":"120","author":"Lv","year":"2015","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2023.140739_bib28","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.fct.2013.05.048","article-title":"Reproductive toxicity and thyroid effects in Sprague Dawley rats exposed to low doses of ethylenethiourea","volume":"59","author":"Maranghi","year":"2013","journal-title":"Food Chem. Toxicol.: an international journal published for the British Industrial Biological Research Association"},{"key":"10.1016\/j.chemosphere.2023.140739_bib29","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.immuni.2014.06.008","article-title":"Macrophage activation and polarization: nomenclature and experimental guidelines","volume":"41","author":"Murray","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.chemosphere.2023.140739_bib30","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/978-1-60761-401-2_11","article-title":"The T-dependent antibody response to keyhole limpet hemocyanin in rodents","volume":"598","author":"Plitnick","year":"2010","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib31","series-title":"NCL Method ITA-7","author":"Potter","year":"2021"},{"key":"10.1016\/j.chemosphere.2023.140739_bib32","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.reprotox.2018.06.010","article-title":"Low dose exposure to HBCD, CB-153 or TCDD induces histopathological and hormonal effects and changes in brain protein and gene expression in juvenile female BALB\/c mice","volume":"80","author":"Rasinger","year":"2018","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib33","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.taap.2007.09.015","article-title":"Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener","volume":"226","author":"Richardson","year":"2008","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib34","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/01926230252824761","article-title":"Qualitative and quantitative analysis of nonneoplastic lesions in toxicology studies","volume":"30","author":"Shackelford","year":"2002","journal-title":"Toxicol. Pathol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.146018","article-title":"BDE-209 caused gut toxicity through modulating the intestinal barrier, oxidative stress, autophagy, inflammation, and apoptosis in mice","volume":"776","author":"Shaoyong","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2023.140739_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.106041","article-title":"Phasing-out of legacy brominated flame retardants: the UNEP Stockholm Convention and other legislative action worldwide","volume":"144","author":"Sharkey","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.chemosphere.2023.140739_bib37","doi-asserted-by":"crossref","first-page":"377","DOI":"10.4162\/nrp.2016.10.4.377","article-title":"Involvement of miR-Let7A in inflammatory response and cell survival\/apoptosis regulated by resveratrol in THP-1 macrophage","volume":"10","author":"Song","year":"2016","journal-title":"Nutr. Res. Prac."},{"key":"10.1016\/j.chemosphere.2023.140739_bib38","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/toxsci\/kfi018","article-title":"Toxicokinetics of BDE 47 in female mice: effect of dose, route of exposure, and time","volume":"82","author":"Staskal","year":"2004","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.chemosphere.2023.140739_bib39","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1098\/rstb.2008.0281","article-title":"Components of plastic: experimental studies in animals and relevance for human health","volume":"364","author":"Talsness","year":"2009","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.chemosphere.2023.140739_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2021.112423","article-title":"2,2\u2032,4,4\u2032-Tetrabromodiphenyl ether (BDE-47) activates Aryl hydrocarbon receptor (AhR) mediated ROS and NLRP3 inflammasome\/p38 MAPK pathway inducing necrosis in cochlear hair cells","volume":"221","author":"Tang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.chemosphere.2023.140739_bib41","doi-asserted-by":"crossref","DOI":"10.1063\/1.4922572","article-title":"In vivo and in vitro toxicological effects of titanium dioxide nanoparticles on small intestine","volume":"1667","author":"Tassinari","year":"2015","journal-title":"AIP Conf. Proc."},{"key":"10.1016\/j.chemosphere.2023.140739_bib42","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1021\/es1035046","article-title":"Total consumer exposure to polybrominated diphenyl ethers in north America and Europe","volume":"45","author":"Trudel","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib43","article-title":"Positive regulation of innate immune response by miRNA-let-7a-5p","volume":"13","author":"Ueta","year":"2022","journal-title":"Front. Genet."},{"key":"10.1016\/j.chemosphere.2023.140739_bib44","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.toxlet.2008.03.003","article-title":"A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE)","volume":"179","author":"Van der Ven","year":"2008","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.chemosphere.2023.140739_bib45","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.taap.2016.01.023","article-title":"Role of miR-155 in fluorooctane sulfonate-induced oxidative hepatic damage via the Nrf2-dependent pathway","volume":"295","author":"Wan","year":"2016","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib46","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1002\/jat.3008","article-title":"In vitro exposure of DE-71, a penta-PBDE mixture, on immune endpoints in bottlenose dolphins (Tursiops truncatus) and B6C3F1 mice","volume":"35","author":"Wirth","year":"2015","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.136562","article-title":"BDE-47 disturbs the immune response of lymphocytes to LPS by downregulating NF-kappaB pathway","volume":"308","author":"Xue","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2023.140739_bib48","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.781815","article-title":"miR-223: an immune regulator in infectious disorders","volume":"12","author":"Yuan","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib49","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/cmi.2014.16","article-title":"Long-term exposure to decabrominated diphenyl ether impairs CD8 T-cell function in adult mice","volume":"11","author":"Zeng","year":"2014","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.chemosphere.2023.140739_bib50","article-title":"Environmental exposure to BDE47 is associated with increased diabetes prevalence: evidence from community-based case-control studies and an animal experiment","volume":"6","author":"Zhang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.chemosphere.2023.140739_bib51","first-page":"3935","article-title":"let-7a suppresses liver fibrosis via TGF\u03b2\/SMAD signaling transduction pathway","volume":"17","author":"Zhang","year":"2019","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.chemosphere.2023.140739_bib52","article-title":"Exposure pathways, levels and toxicity of polybrominated diphenyl ethers in humans: a review","volume":"187","author":"Zhineng","year":"2020","journal-title":"Environ. Res."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653523030096?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653523030096?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:43:11Z","timestamp":1758634991000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653523030096"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":52,"alternative-id":["S0045653523030096"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2023.140739","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The environmental pollutant BDE-47 modulates immune responses in in vitro and in vivo murine models","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2023.140739","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"140739"}}