{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T23:54:35Z","timestamp":1787356475237,"version":"build-2736575974"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31670519,22276093,31870492"],"award-info":[{"award-number":["31670519,22276093,31870492"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31971517"],"award-info":[{"award-number":["31971517"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017547","name":"Jiangsu Association for Science and Technology","doi-asserted-by":"publisher","award":["TJ-2022-054"],"award-info":[{"award-number":["TJ-2022-054"]}],"id":[{"id":"10.13039\/501100017547","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.chemosphere.2024.143466","type":"journal-article","created":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T03:12:12Z","timestamp":1728011532000},"page":"143466","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Early pregnancy exposure to Microcystin-LR compromises endometrial decidualization in mice via the PI3K\/AKT\/FOXO1 signaling pathway"],"prefix":"10.1016","volume":"366","author":[{"given":"Pinru","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meihong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibin","family":"Gan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjiao","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiang","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.chemosphere.2024.143466_bib1","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1038\/s41556-021-00637-6","article-title":"Control of endothelial quiescence by FOXO-regulated metabolites","volume":"23","author":"Andrade","year":"2021","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/s41586-023-05869-0","article-title":"Spatial multiomics map of trophoblast development in early pregnancy","volume":"616","author":"Arutyunyan","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.chemosphere.2024.143466_bib3","first-page":"1","article-title":"Differential regulation of mTORC1 and mTORC2 is critical for 8-Br-cAMP-induced decidualization","volume":"50","author":"Baek","year":"2018","journal-title":"Exp. Mol. Med."},{"key":"10.1016\/j.chemosphere.2024.143466_bib4","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1021\/acs.est.1c04296","article-title":"Identification of novel microcystins using high-resolution MS and MSn with Python code","volume":"56","author":"Baliu-Rodriguez","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib5","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/aji.12472","article-title":"Secrets of endometrial receptivity: some are hidden in uterine secretome","volume":"75","author":"Bhusane","year":"2016","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib6","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1038\/s41556-022-01011-w","article-title":"PTEN directs developmental and metabolic signaling for innate-like T cell fate and tissue homeostasis","volume":"24","author":"Blanco","year":"2022","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib7","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/jcp.1041630105","article-title":"Laminin decreases PRL and IGFBP-1 expression during in vitro decidualization of human endometrial stromal cells","volume":"163","author":"Brar","year":"1995","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib8","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1038\/s41420-022-01196-x","article-title":"Endometrial stromal PRMT5 plays a crucial role in decidualization by regulating NF-\u03baB signaling in endometriosis","volume":"8","author":"Cai","year":"2022","journal-title":"Cell Death Discov"},{"key":"10.1016\/j.chemosphere.2024.143466_bib9","doi-asserted-by":"crossref","first-page":"1754","DOI":"10.1038\/nm.3012","article-title":"Mechanisms of implantation: strategies for successful pregnancy","volume":"18","author":"Cha","year":"2012","journal-title":"Nat Med"},{"key":"10.1016\/j.chemosphere.2024.143466_bib10","doi-asserted-by":"crossref","DOI":"10.59717\/j.xinn-life.2023.100038","article-title":"Nontraditional biomanipulation: a powerful ecotechnology to combat cyanobacterial blooms in eutrophic freshwaters","volume":"1","author":"Chen","year":"2023","journal-title":"The Innovation Life"},{"key":"10.1016\/j.chemosphere.2024.143466_bib11","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1007\/s00018-017-2687-6","article-title":"Microcystin-leucine-arginine causes blood-testis barrier disruption and degradation of occludin mediated by matrix metalloproteinase-8","volume":"75","author":"Chen","year":"2018","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.chemosphere.2024.143466_bib12","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1152\/physrev.00031.2019","article-title":"Physiology of the endometrium and regulation of menstruation","volume":"100","author":"Critchley","year":"2020","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.chemosphere.2024.143466_bib13","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.cmet.2007.10.002","article-title":"The biology of cancer: metabolic reprogramming fuels cell growth and proliferation","volume":"7","author":"DeBerardinis","year":"2008","journal-title":"Cell Metab"},{"key":"10.1016\/j.chemosphere.2024.143466_bib14","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1186\/s13046-018-0980-3","article-title":"IMPDH2 promotes colorectal cancer progression through activation of the PI3K\/AKT\/mTOR and PI3K\/AKT\/FOXO1 signaling pathways","volume":"37","author":"Duan","year":"2018","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.chemosphere.2024.143466_bib15","doi-asserted-by":"crossref","first-page":"15818","DOI":"10.1021\/acs.est.2c02287","article-title":"Microcystin-LR combined with cadmium exposures and the risk of chronic kidney disease: a case-control study in Central China","volume":"56","author":"Feng","year":"2022","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib16","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1289\/ehp.1104693","article-title":"World Health Organization discontinues its drinking-water guideline for manganese","volume":"120","author":"Frisbie","year":"2012","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2024.143466_bib17","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201948791","article-title":"USP1 deubiquitinates Akt to inhibit PI3K-Akt-FoxO signaling in muscle during prolonged starvation","volume":"21","author":"Goldbraikh","year":"2020","journal-title":"EMBO Rep."},{"key":"10.1016\/j.chemosphere.2024.143466_bib18","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s12974-019-1474-8","article-title":"Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K\/AKT\/FoxO1 pathway","volume":"16","author":"Guo","year":"2019","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.chemosphere.2024.143466_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2023.114189","article-title":"Microcystin-LR prenatal exposure drives preeclampsia-like changes in mice by inhibiting the expression of TGF-\u03b2 and VEGFA","volume":"182","author":"Guo","year":"2023","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.fct.2022.113454","article-title":"Microcystin-LR inhibits early pregnancy by impairing the vascular network of luteum: involvement of the MEK\/ERK\/SP1\/VEGFR2 axis","volume":"170","author":"Guo","year":"2022","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.140694","article-title":"Photocatalytic degradation of microcystin-LR by modified TiO(2) photocatalysis: a review","volume":"743","author":"He","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2024.143466_bib22","doi-asserted-by":"crossref","first-page":"11674","DOI":"10.1073\/pnas.1921015117","article-title":"The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B(4) axis","volume":"117","author":"Hosooka","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.chemosphere.2024.143466_bib23","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ebiom.2019.09.002","article-title":"FoxO1-mediated inhibition of STAT1 alleviates tubulointerstitial fibrosis and tubule apoptosis in diabetic kidney disease","volume":"48","author":"Huang","year":"2019","journal-title":"EBioMedicine"},{"key":"10.1016\/j.chemosphere.2024.143466_bib24","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.scitotenv.2014.04.037","article-title":"Bioaccumulation of microcystins (MCs) in four fish species from Lake Taihu, China: assessment of risks to humans","volume":"487","author":"Jia","year":"2014","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2024.143466_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2022.119222","article-title":"BHPF exposure impairs mouse and human decidualization","volume":"304","author":"Jin","year":"2022","journal-title":"Environ Pollut"},{"key":"10.1016\/j.chemosphere.2024.143466_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2019.105194","article-title":"Multimedia distributions, bioaccumulation, and trophic transfer of microcystins in the Geum River Estuary, Korea: application of compound-specific isotope analysis of amino acids","volume":"133","author":"Kim","year":"2019","journal-title":"Environ. Int."},{"key":"10.1016\/j.chemosphere.2024.143466_bib27","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.envpol.2016.11.029","article-title":"Exposure to benzo[a]pyrene impairs decidualization and decidual angiogenesis in mice during early pregnancy","volume":"222","author":"Li","year":"2017","journal-title":"Environ Pollut"},{"key":"10.1016\/j.chemosphere.2024.143466_bib28","article-title":"Serum microcystin-LR levels and risk of gestational diabetes mellitus: a Chinese nested case-control study","volume":"13","author":"Lin","year":"2022","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.144070","article-title":"Microcystin-leucine arginine exposure contributes to apoptosis and follicular atresia in mice ovaries by endoplasmic reticulum stress-upregulated Ddit3","volume":"756","author":"Liu","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2024.143466_bib30","doi-asserted-by":"crossref","first-page":"2196","DOI":"10.1038\/s41396-019-0417-9","article-title":"Response of the eukaryotic plankton community to the cyanobacterial biomass cycle over 6 years in two subtropical reservoirs","volume":"13","author":"Liu","year":"2019","journal-title":"Isme j"},{"key":"10.1016\/j.chemosphere.2024.143466_bib31","doi-asserted-by":"crossref","first-page":"2511","DOI":"10.1080\/15548627.2020.1833515","article-title":"Rapamycin prevents spontaneous abortion by triggering decidual stromal cell autophagy-mediated NK cell residence","volume":"17","author":"Lu","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.chemosphere.2024.143466_bib32","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.celrep.2014.12.052","article-title":"Ancient transposable elements transformed the uterine regulatory landscape and transcriptome during the evolution of mammalian pregnancy","volume":"10","author":"Lynch","year":"2015","journal-title":"Cell Rep."},{"key":"10.1016\/j.chemosphere.2024.143466_bib33","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2200252119","article-title":"Extracellular vesicles secreted by human uterine stromal cells regulate decidualization, angiogenesis, and trophoblast differentiation","volume":"119","author":"Ma","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.chemosphere.2024.143466_bib34","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21114092","article-title":"Endometrial decidualization: the primary driver of pregnancy health","volume":"21","author":"Ng","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.chemosphere.2024.143466_bib35","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0140-6736(97)12285-1","article-title":"Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil","volume":"352","author":"Pouria","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.chemosphere.2024.143466_bib36","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1021\/acs.analchem.3c04047","article-title":"Identification of serine-containing microcystins by UHPLC-MS\/MS using thiol and sulfoxide derivatizations and detection of novel neutral losses","volume":"96","author":"Premathilaka","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.chemosphere.2024.143466_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2024.121121","article-title":"Fate, abundance and ecological risks of microcystins in aquatic environment: the implication of microplastics","volume":"251","author":"Ren","year":"2024","journal-title":"Water Res."},{"key":"10.1016\/j.chemosphere.2024.143466_bib38","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.fertnstert.2022.04.023","article-title":"Immune determinants of endometrial receptivity: a biological perspective","volume":"117","author":"Robertson","year":"2022","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.chemosphere.2024.143466_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/toxins16050212","article-title":"Exposure to microcystin-LR promotes colorectal cancer progression by altering gut microbiota and associated metabolites in APC(min\/+) mice","volume":"16","author":"Song","year":"2024","journal-title":"Toxins"},{"key":"10.1016\/j.chemosphere.2024.143466_bib40","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1001\/jama.2023.5302","article-title":"Prednisone vs placebo and live birth in patients with recurrent implantation failure undergoing in vitro fertilization: a randomized clinical trial","volume":"329","author":"Sun","year":"2023","journal-title":"JAMA"},{"key":"10.1016\/j.chemosphere.2024.143466_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2022.101874","article-title":"Transcriptional coactivator PGC-1\u03b1 contributes to decidualization by forming a histone-modifying complex with C\/EBP\u03b2 and p300","volume":"298","author":"Takagi","year":"2022","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.chemosphere.2024.143466_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.112174","article-title":"Promethazine inhibits proliferation and promotes apoptosis in colorectal cancer cells by suppressing the PI3K\/AKT pathway","volume":"143","author":"Tan","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.chemosphere.2024.143466_bib43","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1007698","article-title":"Genome amplification and cellular senescence are hallmarks of human placenta development","volume":"14","author":"Velicky","year":"2018","journal-title":"PLoS Genet."},{"key":"10.1016\/j.chemosphere.2024.143466_bib44","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jhazmat.2019.03.106","article-title":"Learning and memory deficits and alzheimer's disease-like changes in mice after chronic exposure to microcystin-LR","volume":"373","author":"Wang","year":"2019","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.chemosphere.2024.143466_bib45","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1038\/s41419-020-2329-z","article-title":"Microcystin-LR ameliorates pulmonary fibrosis via modulating CD206(+) M2-like macrophage polarization","volume":"11","author":"Wang","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.chemosphere.2024.143466_bib46","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.scitotenv.2019.06.387","article-title":"Blood-brain barrier disruption and inflammation reaction in mice after chronic exposure to Microcystin-LR","volume":"689","author":"Wang","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2024.143466_bib47","doi-asserted-by":"crossref","DOI":"10.1289\/EHP12034","article-title":"Effects of cyanobacterial harmful algal bloom toxin microcystin-LR on gonadotropin-dependent ovarian follicle maturation and ovulation in mice","volume":"131","author":"Wang","year":"2023","journal-title":"Environ. Health Perspect."},{"key":"10.1016\/j.chemosphere.2024.143466_bib48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.etap.2013.10.012","article-title":"Reproductive toxicity on female mice induced by microcystin-LR","volume":"37","author":"Wu","year":"2014","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib49","doi-asserted-by":"crossref","first-page":"5212","DOI":"10.3390\/toxins7124872","article-title":"MC-LR exposure leads to subfertility of female mice and induces oxidative stress in granulosa cells","volume":"7","author":"Wu","year":"2015","journal-title":"Toxins"},{"key":"10.1016\/j.chemosphere.2024.143466_bib50","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.154437","article-title":"Maternal DBP exposure promotes synaptic formation in offspring by activating astrocytes via the AKT\/NF-\u03baB\/IL-6\/JAK2\/STAT3 signaling pathway","volume":"829","author":"Xia","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2024.143466_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.128440","article-title":"Microcystin-leucine-arginine induces apical ectoplasmic specialization disassembly","volume":"264","author":"Xu","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2024.143466_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121801","article-title":"Enhancing arsenate metabolism in Microcystis aeruginosa and relieving risks of arsenite and microcystins by nano-Fe(2)O(3) under dissolved organic phosphorus conditions","volume":"330","author":"Xu","year":"2023","journal-title":"Environ Pollut"},{"key":"10.1016\/j.chemosphere.2024.143466_bib53","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.269","article-title":"CD73 alleviates GSDMD-mediated microglia pyroptosis in spinal cord injury through PI3K\/AKT\/Foxo1 signaling","volume":"11","author":"Xu","year":"2021","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.chemosphere.2024.143466_bib54","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/s11658-018-0115-z","article-title":"Microcystin-LR regulates circadian clock and antioxidant gene expression in cultured rat cardiomyocytes","volume":"23","author":"Xu","year":"2018","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.chemosphere.2024.143466_bib55","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1093\/humrep\/deac229","article-title":"Basigin is necessary for normal decidualization of human uterine stromal cells","volume":"37","author":"Yang","year":"2022","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.chemosphere.2024.143466_bib56","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1093\/humupd\/dmac026","article-title":"Lipid metabolism and endometrial receptivity","volume":"28","author":"Yang","year":"2022","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.chemosphere.2024.143466_bib57","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.129793","article-title":"Long-term environmental levels of microcystin-LR exposure induces colorectal chronic inflammation, fibrosis and barrier disruption via CSF1R\/Rap1b signaling pathway","volume":"440","author":"Yang","year":"2022","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.chemosphere.2024.143466_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.121785","article-title":"Exposure to acrylamide inhibits uterine decidualization via suppression of cyclin D3\/p21 and apoptosis in mice","volume":"388","author":"Yu","year":"2020","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.chemosphere.2024.143466_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.167018","article-title":"The mechanisms of microcystin-LR-induced genotoxicity and neurotoxicity in fish and mammals: bibliometric analysis and meta-analysis","volume":"905","author":"Zhang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.chemosphere.2024.143466_bib60","doi-asserted-by":"crossref","first-page":"11319","DOI":"10.1021\/es3024989","article-title":"Microcystin-LR promotes melanoma cell invasion and enhances matrix metalloproteinase-2\/-9 expression mediated by NF-\u03baB activation","volume":"46","author":"Zhang","year":"2012","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib61","doi-asserted-by":"crossref","first-page":"3137","DOI":"10.1021\/acs.est.5b03369","article-title":"First identification of the toxicity of microcystins on pancreatic islet function in humans and the involved potential biomarkers","volume":"50","author":"Zhao","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.chemosphere.2024.143466_bib62","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1002\/hep.29310","article-title":"Serum microcystin levels positively linked with risk of hepatocellular carcinoma: a case-control study in southwest China","volume":"66","author":"Zheng","year":"2017","journal-title":"Hepatology"},{"key":"10.1016\/j.chemosphere.2024.143466_bib63","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1186\/s12958-022-01042-w","article-title":"Decreased CD44v3 expression impairs endometrial stromal cell proliferation and decidualization in women with recurrent implantation failure","volume":"20","author":"Zhou","year":"2022","journal-title":"Reprod. Biol. Endocrinol."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653524023646?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653524023646?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:24:26Z","timestamp":1777465466000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653524023646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":63,"alternative-id":["S0045653524023646"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2024.143466","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early pregnancy exposure to Microcystin-LR compromises endometrial decidualization in mice via the PI3K\/AKT\/FOXO1 signaling pathway","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2024.143466","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"143466"}}