{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T13:22:23Z","timestamp":1778851343177,"version":"3.51.4"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","award":["39-600\/2010"],"award-info":[{"award-number":["39-600\/2010"]}],"id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001501","name":"University Grants Commission","doi-asserted-by":"publisher","award":["10\/01\/2011"],"award-info":[{"award-number":["10\/01\/2011"]}],"id":[{"id":"10.13039\/501100001501","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chemosphere"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.chemosphere.2025.144202","type":"journal-article","created":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T15:15:42Z","timestamp":1739286942000},"page":"144202","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Mancozeb exposure disrupts endocrine function of the ovary and thyroid in Red Munia (Amandava amandava)"],"prefix":"10.1016","volume":"374","author":[{"given":"Banalata","family":"Mohanty","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.chemosphere.2025.144202_bib1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.bbrc.2020.04.051","article-title":"In vitro and in vivo impairment of embryo implantation by commonly used fungicide Mancozeb","volume":"527","author":"Akthar","year":"2020","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.chemosphere.2025.144202_bib2","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.etap.2018.03.009","article-title":"Effects of mancozeb, metalaxyl and tebuconazole on steroid production by bovine luteal cells in vitro","volume":"59","author":"Atmaca","year":"2018","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.chemosphere.2025.144202_bib3","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1093\/toxsci\/kfr006","article-title":"Exposure to widely used fungicide mancozeb causes thyroid hormone disruption in rat dams but no behavioral effects in the offsprings","volume":"120","author":"Axelstad","year":"2011","journal-title":"Toxicol. Sci."},{"issue":"3","key":"10.1016\/j.chemosphere.2025.144202_bib4","doi-asserted-by":"crossref","first-page":"235","DOI":"10.2486\/indhealth.39.235","article-title":"Induction of gonadal toxicity to female rats after chronic exposure to mancozeb","volume":"39","author":"Baligar","year":"2001","journal-title":"Ind. Health"},{"key":"10.1016\/j.chemosphere.2025.144202_bib5","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1515\/JBCPP.2004.15.3-4.241","article-title":"Morphometric analysis of follicular growth and biochemical constituents in albino rats exposed to mancozeb","volume":"15","author":"Baligar","year":"2004","journal-title":"J. Basic Clin. Physiol. Pharmacol."},{"key":"10.1016\/j.chemosphere.2025.144202_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2020.103408","article-title":"Thyroid disrupting pesticides mancozeb and fipronil in mixture caused oxidative damage and genotoxicity in lymphoid organs of mice","volume":"79","author":"Bano","year":"2020","journal-title":"Environ. Toxicol. Pharmacol."},{"issue":"239","key":"10.1016\/j.chemosphere.2025.144202_bib7","article-title":"Low level of mancozeb exposure affects ovary in mice","volume":"1","author":"Bao","year":"2022","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.chemosphere.2025.144202_bib8","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.ygcen.2014.02.007","article-title":"Pesticides in mixture disrupt metabolic regulation: in silico and in vivo analysis of cumulative toxicity of mancozeb and imidacloprid on body weight of mice","volume":"205","author":"Bhaskar","year":"2014","journal-title":"Gen. Comp. Endocrinol."},{"issue":"7","key":"10.1016\/j.chemosphere.2025.144202_bib9","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.3390\/ijerph17072580","article-title":"Association between female reproductive health and mancozeb: systematic review of experimental models","volume":"17","author":"Bianchi","year":"2020","journal-title":"Int. J. Environ. Res. Publ. Health"},{"issue":"2","key":"10.1016\/j.chemosphere.2025.144202_bib10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2486\/indhealth.40.191","article-title":"Anti-implantation effect of a carbamate fungicide mancozeb in albino mice","volume":"40","author":"Bindali","year":"2002","journal-title":"Ind. Health"},{"issue":"29","key":"10.1016\/j.chemosphere.2025.144202_bib11","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.2174\/138161207782110516","article-title":"The effects of the endocrine disruptors dithiocarbamates on the mammalian ovary with particular regard to mancozeb","volume":"13","author":"Cecconi","year":"2007","journal-title":"Curr. Pharm. Des."},{"issue":"1\u20133","key":"10.1016\/j.chemosphere.2025.144202_bib12","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0378-4274(02)00182-0","article-title":"Ethylenethiourea in urine as an indicator of exposure to mancozeb in vineyard workers","volume":"134","author":"Colosio","year":"2002","journal-title":"Toxicol. Lett."},{"issue":"5","key":"10.1016\/j.chemosphere.2025.144202_bib13","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1530\/REP-11-0136","article-title":"Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling","volume":"142","author":"Craig","year":"2011","journal-title":"Reproduction"},{"issue":"4","key":"10.1016\/j.chemosphere.2025.144202_bib14","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1210\/endo-104-4-919","article-title":"Thiourea and cyanamide as inhibitors of thyroid peroxidase: the role of iodide","volume":"104","author":"Davidson","year":"1979","journal-title":"Endocrinology"},{"issue":"5","key":"10.1016\/j.chemosphere.2025.144202_bib15","doi-asserted-by":"crossref","first-page":"609","DOI":"10.23736\/S0026-4784.18.04271-5","article-title":"Crosstalk between gonadotropins and thyroid axis","volume":"70","author":"De Vincentis","year":"2018","journal-title":"Minerva Ginecol."},{"issue":"3","key":"10.1016\/j.chemosphere.2025.144202_bib16","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s11250-021-02854-5","article-title":"Impairment of caprine oocyte maturation in vitro and alteration of granulosa cells functions by widely used fungicide mancozeb","volume":"53","author":"Dinisri","year":"2021","journal-title":"Trop. Anim. Health Prod."},{"issue":"2","key":"10.1016\/j.chemosphere.2025.144202_bib17","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1021\/tx00014a003","article-title":"Mechanism of thyroid peroxidase inhibition by ethylenethiourea","volume":"3","author":"Doerge","year":"1990","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.chemosphere.2025.144202_bib18","series-title":"Reregistration Eligibility Decision for Mancozeb.","first-page":"1","year":"2005"},{"key":"10.1016\/j.chemosphere.2025.144202_bib19","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1177\/0748233719890965","article-title":"Massood, E. Mancozeb exposure during development and lactation periods results in decreased oocyte maturation, fertilization rates, and implantation in the first-generation mice pups: protective effect of vitamins E and C","volume":"35","author":"Esmaiel","year":"2019","journal-title":"Toxicol. Ind. Health"},{"issue":"5","key":"10.1016\/j.chemosphere.2025.144202_bib20","doi-asserted-by":"crossref","first-page":"698","DOI":"10.3390\/biology12050698","article-title":"Ultrastructural evaluation of mouse oocytes exposed in vitro to different concentrations of the fungicide mancozeb","volume":"12","author":"Gatti","year":"2023","journal-title":"Biology"},{"key":"10.1016\/j.chemosphere.2025.144202_bib21","series-title":"Estrilid Finches of the World","author":"Goodwin","year":"1980"},{"key":"10.1016\/j.chemosphere.2025.144202_bib22","series-title":"Review Report for the Active Substance Mancozeb.","first-page":"1","article-title":"Directorate D-food safety: production and distribution chain","year":"2009"},{"issue":"10","key":"10.1016\/j.chemosphere.2025.144202_bib23","doi-asserted-by":"crossref","DOI":"10.1210\/endocr\/bqac128","article-title":"Sex-specific effects of endocrine-disrupting chemicals on brain monoamines and cognitive behavior","volume":"163","author":"Hilz","year":"2022","journal-title":"Endocrinology"},{"issue":"1 Pt B","key":"10.1016\/j.chemosphere.2025.144202_bib24","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.tiv.2015.09.018","article-title":"Mancozeb affects mitochondrial activity, redox status and ATP production in mouse granulosa cells","volume":"30","author":"Iorio","year":"2015","journal-title":"Toxicol. Vitro"},{"issue":"1","key":"10.1016\/j.chemosphere.2025.144202_bib25","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/s13273-018-0013-5","article-title":"Toxicological evaluation of dithiocarbamate fungicide MCZ on the endocrine functions in male rats","volume":"14","author":"Kwon","year":"2018","journal-title":"Mol. Cell. Toxicol."},{"key":"10.1016\/j.chemosphere.2025.144202_bib26","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.watres.2016.07.006","article-title":"Kinetic modelling of mancozeb hydrolysis and photolysis to ethylenethiourea and other by-products in water","volume":"102","author":"L\u00f3pez-Fern\u00e1ndez","year":"2016","journal-title":"Water Res."},{"issue":"2","key":"10.1016\/j.chemosphere.2025.144202_bib27","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0890-6238(00)00064-2","article-title":"Effect of mancozeb on ovarian compensatory hypertrophy and biochemical constituents in hemicastrated albino rat","volume":"14","author":"Mahadevaswami","year":"2000","journal-title":"Reprod. Toxicol."},{"issue":"1","key":"10.1016\/j.chemosphere.2025.144202_bib28","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-69325-z","article-title":"LH supplementation of ovarian stimulation protocols influences follicular fluid steroid composition contributing to the improvement of ovarian response in poor responder women","volume":"10","author":"Marchiani","year":"2020","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.chemosphere.2025.144202_bib29","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1177\/0269881109348162","article-title":"Lactational exposure to atypical antipsychotic drugs disrupts the pituitary-testicular axis in mice neonates during post-natal development","volume":"24","author":"Mishra","year":"2010","journal-title":"J. Psychopharmacol."},{"issue":"4","key":"10.1016\/j.chemosphere.2025.144202_bib30","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4149\/endo_2014_04_201","article-title":"Impact of endocrine disruptors on ovarian steroidogenesis","volume":"48","author":"Mlynarcikova","year":"2014","journal-title":"Endocr. Regul."},{"key":"10.1016\/j.chemosphere.2025.144202_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.pestbp.2024.105800","article-title":"a. Pesticides exposure and compromised fitness in wild birds: focusing on the reproductive endocrine disruption","volume":"199","author":"Mohanty","year":"2024","journal-title":"Pestic. Biochem. Physiol."},{"issue":"6","key":"10.1016\/j.chemosphere.2025.144202_bib32","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1159\/000536418","article-title":"Seasonality of reproduction in a subtropical free living finch Amandava amandava: plasticity of adenohypophyseal gonadotropes, lactotropes and thyrotropes","volume":"114","author":"Mohanty","year":"2024","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.chemosphere.2025.144202_bib33","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.reprotox.2017.04.006","article-title":"Thyroid disrupting pesticides impair the hypothalamic-pituitary-testicular axis of a wildlife bird, Amandava amandava","volume":"71","author":"Mohanty","year":"2017","journal-title":"Reprod. Toxicol."},{"issue":"7185","key":"10.1016\/j.chemosphere.2025.144202_bib34","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/nature06738","article-title":"Thyrotrophin in the pars tuberalis triggers photoperiodic response","volume":"452","author":"Nakao","year":"2008","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.chemosphere.2025.144202_bib35","doi-asserted-by":"crossref","first-page":"89","DOI":"10.5271\/sjweh.855","article-title":"Indicators of mancozeb exposure in relation to thyroid cancer and neural tube defects in farmers' families","volume":"31","author":"Nordby","year":"2005","journal-title":"Scand. J. Work. Environ. Health"},{"key":"10.1016\/j.chemosphere.2025.144202_bib36","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.neubiorev.2020.11.015","article-title":"Sex-biased impact of endocrine disrupting chemicals on behavioral development and vulnerability to disease: of mice and children","volume":"121","author":"Palanza","year":"2021","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1","key":"10.1016\/j.chemosphere.2025.144202_bib37","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1262\/jrd.2017-143","article-title":"Mancozeb impairs the ultrastructure of mouse granulosa cells in a dose-dependent manner","volume":"64","author":"Palmerini","year":"2018","journal-title":"J. Reprod. Dev."},{"key":"10.1016\/j.chemosphere.2025.144202_bib38","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.chemosphere.2014.11.061","article-title":"The neonicotinoid pesticide imidacloprid and the dithiocarbamate fungicide mancozeb disrupt the pituitary-thyroid axis of a wildlife bird","volume":"122","author":"Pandey","year":"2014","journal-title":"Chemosphere"},{"key":"10.1016\/j.chemosphere.2025.144202_bib39","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.neuro.2017.02.010","article-title":"Disruption of the hypothalamic-pituitary-thyroid axis on co-exposures to dithiocarbamate and neonicotinoid pesticides: study in a wildlife bird, Amandava amandava","volume":"60","author":"Pandey","year":"2017","journal-title":"Neurotoxicology"},{"issue":"9","key":"10.1016\/j.chemosphere.2025.144202_bib40","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1002\/jez.2740","article-title":"Role of the testicular capsule in seasonal modulation of the testis","volume":"339","author":"Pandey","year":"2023","journal-title":"J Exp Zool A Ecol Integr Physiol."},{"key":"10.1016\/j.chemosphere.2025.144202_bib41","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.physbeh.2017.01.030","article-title":"Endocrine disrupting pesticides impair the neuroendocrine regulation of reproductive behaviors and secondary sexual characters of red munia (Amandava amandava)","volume":"173","author":"Pandey","year":"2017","journal-title":"Physiol. Behav."},{"issue":"2","key":"10.1016\/j.chemosphere.2025.144202_bib42","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.taap.2012.02.005","article-title":"The fungicide mancozeb induces toxic effects on mammalian granulosa cells","volume":"260","author":"Paro","year":"2012","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"2","key":"10.1016\/j.chemosphere.2025.144202_bib44","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.reprotox.2005.08.004","article-title":"Mancozeb exposure in vivo impairs mouse oocyte fertilizability","volume":"21","author":"Rossi","year":"2006","journal-title":"Reprod. Toxicol."},{"key":"10.1016\/j.chemosphere.2025.144202_bib45","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.envint.2016.11.006","article-title":"A systematic review of Mancozeb as a reproductive and developmental hazard","volume":"99","author":"Runkle","year":"2017","journal-title":"Environ. Int."},{"key":"10.1016\/j.chemosphere.2025.144202_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114471","article-title":"Mancozeb induces nephrotoxicity by impairing the oxidative phosphorylation pathway: a transcriptome study","volume":"249","author":"Zhang","year":"2023","journal-title":"Ecotoxicol. Environ. Saf."}],"container-title":["Chemosphere"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653525001444?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045653525001444?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:26:04Z","timestamp":1777465564000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045653525001444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":45,"alternative-id":["S0045653525001444"],"URL":"https:\/\/doi.org\/10.1016\/j.chemosphere.2025.144202","relation":{},"ISSN":["0045-6535"],"issn-type":[{"value":"0045-6535","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mancozeb exposure disrupts endocrine function of the ovary and thyroid in Red Munia (Amandava amandava)","name":"articletitle","label":"Article Title"},{"value":"Chemosphere","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chemosphere.2025.144202","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"144202"}}