{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T08:38:14Z","timestamp":1769157494898,"version":"3.49.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,2,24]],"date-time":"2016-02-24T00:00:00Z","timestamp":1456272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.chest.2016.02.636","type":"journal-article","created":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T16:18:57Z","timestamp":1455639537000},"page":"210-218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Clinical Utility of a Bronchial Genomic Classifier in Patients With Suspected Lung Cancer"],"prefix":"10.1016","volume":"150","author":[{"given":"Anil","family":"Vachani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duncan H.","family":"Whitney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward C.","family":"Parsons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Lenburg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Scott","family":"Ferguson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard A.","family":"Silvestri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avrum","family":"Spira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.chest.2016.02.636_bib1","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1164\/rccm.201505-0990OC","article-title":"Recent trends in the identification of incidental pulmonary nodules","volume":"192","author":"Gould","year":"2015","journal-title":"Am J. Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.chest.2016.02.636_bib2","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1056\/NEJMoa1102873","article-title":"Reduced lung-cancer mortality with low-dose computed tomographic screening","volume":"365","author":"Aberle","year":"2011","journal-title":"N\u00a0Engl J Med"},{"issue":"5\u00a0suppl","key":"10.1016\/j.chest.2016.02.636_bib3","doi-asserted-by":"crossref","first-page":"e142S","DOI":"10.1378\/chest.12-2353","article-title":"Establishing the diagnosis of lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"143","author":"Rivera","year":"2013","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.chest.2016.02.636_bib4","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1378\/chest.11-1764","article-title":"Meta-analysis of guided bronchoscopy for the evaluation of the pulmonary nodule","volume":"142","author":"Wang Memoli","year":"2012","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.chest.2016.02.636_bib5","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1164\/rccm.201507-1332OC","article-title":"Diagnostic yield and complications of bronchoscopy for peripheral lung lesions: results of the AQuIRE Registry","volume":"193","author":"Ost","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.chest.2016.02.636_bib6","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1164\/rccm.201104-0679CI","article-title":"Decision making in patients with pulmonary nodules","volume":"185","author":"Ost","year":"2012","journal-title":"Am J\u00a0Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.chest.2016.02.636_bib7","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12920-015-0091-3","article-title":"Derivation of a bronchial genomic classifier for lung cancer in a prospective study of patients undergoing diagnostic bronchoscopy","volume":"8","author":"Whitney","year":"2015","journal-title":"BMC Med Genomics"},{"issue":"3","key":"10.1016\/j.chest.2016.02.636_bib8","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1056\/NEJMoa1504601","article-title":"A\u00a0bronchial genomic classifier for the diagnostic evaluation of lung cancer","volume":"373","author":"Silvestri","year":"2015","journal-title":"N\u00a0Engl J Med"},{"issue":"27","key":"10.1016\/j.chest.2016.02.636_bib9","doi-asserted-by":"crossref","first-page":"10143","DOI":"10.1073\/pnas.0401422101","article-title":"Effects of\u00a0cigarette smoke on the human airway\u00a0epithelial cell transcriptome","volume":"101","author":"Spira","year":"2004","journal-title":"Proc\u00a0Natl Acad Sci USA"},{"issue":"3","key":"10.1016\/j.chest.2016.02.636_bib10","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/nm1556","article-title":"Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer","volume":"13","author":"Spira","year":"2007","journal-title":"Nat Med"},{"issue":"4","key":"10.1016\/j.chest.2016.02.636_bib11","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1136\/thoraxjnl-2011-200736","article-title":"CT\u00a0screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT","volume":"67","author":"Saghir","year":"2012","journal-title":"Thorax"},{"issue":"5","key":"10.1016\/j.chest.2016.02.636_bib12","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1164\/rccm.200901-0076OC","article-title":"A\u00a0randomized study of lung cancer screening with spiral\u00a0computed tomography: three-year results from the DANTE trial","volume":"180","author":"Infante","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"issue":"23","key":"10.1016\/j.chest.2016.02.636_bib13","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1056\/NEJMoa0906085","article-title":"Management of lung nodules detected by volume CT scanning","volume":"361","author":"van Klaveren","year":"2009","journal-title":"N\u00a0Engl J\u00a0Med"},{"issue":"6","key":"10.1016\/j.chest.2016.02.636_bib14","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1378\/chest.15-0630","article-title":"Management of pulmonary nodules by community pulmonologists: a multicenter observational study","volume":"148","author":"Tanner","year":"2015","journal-title":"Chest"},{"issue":"25","key":"10.1016\/j.chest.2016.02.636_bib15","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1056\/NEJMcp012290","article-title":"Clinical practice. The solitary pulmonary nodule","volume":"348","author":"Ost","year":"2003","journal-title":"N\u00a0Engl J Med"},{"issue":"5\u00a0suppl","key":"10.1016\/j.chest.2016.02.636_bib16","doi-asserted-by":"crossref","first-page":"e93S","DOI":"10.1378\/chest.12-2351","article-title":"Evaluation of individuals with pulmonary nodules: when is it lung cancer? Diagnosis and management of\u00a0lung cancer, 3rd ed: American College of\u00a0Chest Physicians evidence-based clinical practice guidelines","volume":"143","author":"Gould","year":"2013","journal-title":"Chest"},{"issue":"1","key":"10.1016\/j.chest.2016.02.636_bib17","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/CPM.0b013e31827a30c1","article-title":"Risks of transthoracic needle biopsy: how high?","volume":"20","author":"Wiener","year":"2013","journal-title":"Clin Pulm Med"},{"issue":"5","key":"10.1016\/j.chest.2016.02.636_bib18","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/01.RVI.0000124951.24134.50","article-title":"Factors associated with pneumothorax and pneumothorax requiring treatment after percutaneous lung biopsy in 443 consecutive patients","volume":"15","author":"Covey","year":"2004","journal-title":"J\u00a0Vasc Interv Radiol"},{"issue":"10","key":"10.1016\/j.chest.2016.02.636_bib19","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1136\/thx.54.10.884","article-title":"Transthoracic needle aspiration biopsy for\u00a0the diagnosis of localised pulmonary lesions: a meta-analysis","volume":"54","author":"Lacasse","year":"1999","journal-title":"Thorax"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216012551?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216012551?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T07:26:49Z","timestamp":1757921209000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369216012551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":19,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S0012369216012551"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2016.02.636","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical Utility of a Bronchial Genomic Classifier in Patients With Suspected Lung Cancer","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2016.02.636","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 The Authors. Published by Elsevier Inc under license from the American College of Chest Physicians.","name":"copyright","label":"Copyright"}]}}