{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:39:34Z","timestamp":1792291174246,"version":"4.4.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1016\/j.chest.2016.08.1476","type":"journal-article","created":{"date-parts":[[2016,10,11]],"date-time":"2016-10-11T23:00:33Z","timestamp":1476226833000},"page":"149-159","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"title":["Prophylaxis Against Atrial Fibrillation After General Thoracic Surgery"],"prefix":"10.1016","volume":"151","author":[{"given":"Bing-Cheng","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong-Yi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi-Wen","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Feng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Tao","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke-Xuan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cai","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.chest.2016.08.1476_bib1","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.jtcvs.2003.07.011","article-title":"Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: analysis of 2588 patients","volume":"127","author":"Vaporciyan","year":"2004","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"5","key":"10.1016\/j.chest.2016.08.1476_bib2","doi-asserted-by":"crossref","first-page":"1766","DOI":"10.1016\/S0003-4975(98)00942-4","article-title":"Incidence and predictors of supraventricular dysrhythmias after pulmonary resection","volume":"66","author":"Curtis","year":"1998","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"10.1016\/j.chest.2016.08.1476_bib3","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1097\/00000542-200212000-00039","article-title":"Perioperative atrial tachyarrhythmias","volume":"97","author":"Amar","year":"2002","journal-title":"Anesthesiology"},{"issue":"22","key":"10.1016\/j.chest.2016.08.1476_bib4","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1016\/j.jacc.2009.09.015","article-title":"Atrial fibrillation after major thoracic surgery: new insights into underlying mechanisms","volume":"54","author":"Dixit","year":"2009","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"2","key":"10.1016\/j.chest.2016.08.1476_bib5","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jtcvs.2005.02.010","article-title":"Atrial fibrillation complicating lung cancer resection","volume":"130","author":"Roselli","year":"2005","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"6","key":"10.1016\/j.chest.2016.08.1476_bib6","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1001\/jama.2014.9143","article-title":"Perioperative atrial fibrillation and the long-term risk of ischemic stroke","volume":"312","author":"Gialdini","year":"2014","journal-title":"JAMA"},{"issue":"6","key":"10.1016\/j.chest.2016.08.1476_bib7","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/j.athoracsur.2014.06.069","article-title":"Postoperative atrial fibrillation prophylaxis after lung surgery: systematic review and meta-analysis","volume":"98","author":"Riber","year":"2014","journal-title":"Ann Thorac Surg"},{"issue":"5","key":"10.1016\/j.chest.2016.08.1476_bib8","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1016\/j.jtcvs.2004.07.042","article-title":"Pharmacologic prophylaxis for postoperative atrial tachyarrhythmia in general thoracic surgery: evidence from randomized clinical trials","volume":"129","author":"Sedrakyan","year":"2005","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"4","key":"10.1016\/j.chest.2016.08.1476_bib9","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1053\/j.semtcvs.2010.12.001","article-title":"Prophylaxis of atrial fibrillation after noncardiac thoracic surgery","volume":"22","author":"Tisdale","year":"2010","journal-title":"Semin Thorac Cardiovasc Surg"},{"issue":"4","key":"10.1016\/j.chest.2016.08.1476_bib10","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.jtcvs.2015.09.041","article-title":"Postoperative atrial fibrillation: is there a need for prevention?","volume":"151","author":"Amar","year":"2016","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"7521","key":"10.1016\/j.chest.2016.08.1476_bib11","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1136\/bmj.331.7521.897","article-title":"Simultaneous comparison of multiple treatments: combining direct and indirect evidence","volume":"331","author":"Caldwell","year":"2005","journal-title":"BMJ"},{"key":"10.1016\/j.chest.2016.08.1476_bib12","doi-asserted-by":"crossref","unstructured":"Higgins J, Green S. Cochrane handbook for systematic reviews of interventions, version 5.1.0 [updated March 2011]. Cochrane Collaboration, 2008. Cochrane Collaboration website. www.cochrane-handbook.org. Accessed March 3,\u00a02016.","DOI":"10.1002\/9780470712184.ch1"},{"issue":"11","key":"10.1016\/j.chest.2016.08.1476_bib13","doi-asserted-by":"crossref","first-page":"777","DOI":"10.7326\/M14-2385","article-title":"The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations","volume":"162","author":"Hutton","year":"2015","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.1016\/j.chest.2016.08.1476_bib14","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/0003-4975(89)90076-3","article-title":"Prevention of arrhythmias by flecainide after noncardiac thoracic surgery","volume":"48","author":"Borgeat","year":"1989","journal-title":"Ann Thorac Surg"},{"issue":"1","key":"10.1016\/j.chest.2016.08.1476_bib15","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/0003-4975(90)90094-M","article-title":"Prophylactic digitalization for thoracotomy: a reassessment","volume":"50","author":"Ritchie","year":"1990","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"10.1016\/j.chest.2016.08.1476_bib16","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1016\/0003-4975(91)91016-O","article-title":"Prevention of arrhythmias after noncardiac thoracic operations: flecainide vs\u00a0digoxin","volume":"51","author":"Borgeat","year":"1991","journal-title":"Ann Thorac Surg"},{"issue":"2","key":"10.1016\/j.chest.2016.08.1476_bib17","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1093\/bja\/66.2.205","article-title":"Effect of verapamil on right ventricular pressure and atrial tachyarrhythmia after thoracotomy","volume":"66","author":"Lindgren","year":"1991","journal-title":"Br J Anaesth"},{"issue":"1","key":"10.1016\/j.chest.2016.08.1476_bib18","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1136\/thx.47.1.41","article-title":"Prophylactic digitalisation in pulmonary surgery","volume":"47","author":"Ritchie","year":"1992","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.chest.2016.08.1476_bib19","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/0003-4975(93)90478-Z","article-title":"Prophylactic digitalization fails to control dysrhythmia in thoracic esophageal operations","volume":"55","author":"Ritchie","year":"1993","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"10.1016\/j.chest.2016.08.1476_bib20","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1378\/chest.105.6.1642","article-title":"Amiodarone and the development of ARDS after lung surgery","volume":"105","author":"Van Mieghem","year":"1994","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.chest.2016.08.1476_bib21","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1055\/s-2007-1012041","article-title":"Prevention of atrial tachyarrhythmias after non-cardiac thoracic surgery by infusion of magnesium sulfate","volume":"44","author":"Terzi","year":"1996","journal-title":"Thorac Cardiovasc Surg"},{"issue":"4","key":"10.1016\/j.chest.2016.08.1476_bib22","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/0003-4975(96)00073-2","article-title":"Verapamil as prophylactic treatment for atrial fibrillation after lung operations","volume":"61","author":"Van Mieghem","year":"1996","journal-title":"Ann Thorac Surg"},{"issue":"5","key":"10.1016\/j.chest.2016.08.1476_bib23","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/S0003-4975(97)80354-2","article-title":"Effects of diltiazem vs\u00a0digoxin on dysrhythmias and cardiac function after pneumonectomy","volume":"63","author":"Amar","year":"1997","journal-title":"Ann Thorac Surg"},{"issue":"6","key":"10.1016\/j.chest.2016.08.1476_bib24","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1016\/S1053-0770(97)90169-5","article-title":"Perioperative metoprolol reduces the frequency of atrial fibrillation after thoracotomy for lung resection","volume":"11","author":"Jakobsen","year":"1997","journal-title":"J\u00a0Cardiothorac Vasc Anesth"},{"issue":"1","key":"10.1016\/j.chest.2016.08.1476_bib25","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0003-4975(98)01226-0","article-title":"Propranolol for the prevention of postoperative arrhythmias in general thoracic surgery","volume":"67","author":"Bayliff","year":"1999","journal-title":"Ann Thorac Surg"},{"issue":"4","key":"10.1016\/j.chest.2016.08.1476_bib26","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1067\/mtc.2000.109538","article-title":"Effects of diltiazem prophylaxis on the incidence and clinical outcome of atrial arrhythmias after thoracic surgery","volume":"120","author":"Amar","year":"2000","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"5","key":"10.1016\/j.chest.2016.08.1476_bib27","first-page":"609","article-title":"Beneficial effects of metoprolol on perioperative cardiac function of elderly esophageal cancer patients","volume":"25","author":"Lai","year":"2006","journal-title":"Chin J Cancer"},{"issue":"3","key":"10.1016\/j.chest.2016.08.1476_bib28","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.athoracsur.2009.04.074","article-title":"A\u00a0randomized trial evaluating amiodarone for prevention of atrial fibrillation after pulmonary resection","volume":"88","author":"Tisdale","year":"2009","journal-title":"Ann Thorac Surg"},{"issue":"1","key":"10.1016\/j.chest.2016.08.1476_bib29","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.jtcvs.2010.01.026","article-title":"A\u00a0randomized, controlled study of amiodarone for prevention of atrial fibrillation after transthoracic esophagectomy","volume":"140","author":"Tisdale","year":"2010","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"2","key":"10.1016\/j.chest.2016.08.1476_bib30","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.jtcvs.2011.09.003","article-title":"Effect of low-dose human atrial natriuretic peptide on postoperative atrial fibrillation in patients undergoing pulmonary resection for lung cancer: a double-blind, placebo-controlled study","volume":"143","author":"Nojiri","year":"2012","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"2","key":"10.1016\/j.chest.2016.08.1476_bib31","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.athoracsur.2011.12.096","article-title":"Amiodarone significantly decreases atrial fibrillation in patients undergoing surgery for lung cancer","volume":"94","author":"Riber","year":"2012","journal-title":"Ann Thorac Surg"},{"issue":"4","key":"10.1016\/j.chest.2016.08.1476_bib32","first-page":"365","article-title":"Comparative efficacy and usefulness of acebutolol and diltiazem for the prevention of atrial fibrillation during perioperative time in patients undergoing pulmonary resection","volume":"61","author":"Ciszewski","year":"2013","journal-title":"Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.chest.2016.08.1476_bib33","first-page":"56","article-title":"A\u00a0comparative study between amiodarone and magnesium sulfate as antiarrhythmic agents for prophylaxis against atrial fibrillation following lobectomy","volume":"27","author":"Khalil","year":"2013","journal-title":"J\u00a0Anesth"},{"issue":"6","key":"10.1016\/j.chest.2016.08.1476_bib34","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.jtcvs.2014.12.016","article-title":"Beneficial effects of perioperative statins for major pulmonary resection","volume":"149","author":"Amar","year":"2015","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"5","key":"10.1016\/j.chest.2016.08.1476_bib35","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1378\/chest.15-0852","article-title":"A\u00a0double-blind placebo-controlled study of the effects of olprinone, a specific phosphodiesterase III inhibitor, for preventing postoperative atrial fibrillation in patients undergoing pulmonary resection for lung cancer","volume":"148","author":"Nojiri","year":"2015","journal-title":"Chest"},{"issue":"2","key":"10.1016\/j.chest.2016.08.1476_bib36","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/SLA.0000000000001626","article-title":"Prevention of atrial fibrillation in high-risk patients undergoing lung cancer surgery: the PRESAGE trial","volume":"264","author":"Cardinale","year":"2016","journal-title":"Ann Surg"},{"key":"10.1016\/j.chest.2016.08.1476_bib37","first-page":"CD003611","article-title":"Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery","volume":"1","author":"Arsenault","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"2 suppl","key":"10.1016\/j.chest.2016.08.1476_bib38","doi-asserted-by":"crossref","first-page":"39S","DOI":"10.1378\/chest.128.2_suppl.39S","article-title":"Pharmacologic prophylaxis: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery","volume":"128","author":"Bradley","year":"2005","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.chest.2016.08.1476_bib39","doi-asserted-by":"crossref","first-page":"e153","DOI":"10.1016\/j.jtcvs.2014.06.036","article-title":"2014 AATS guidelines for the prevention and management of perioperative atrial fibrillation and flutter for thoracic surgical procedures","volume":"148","author":"Frendl","year":"2014","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.chest.2016.08.1476_bib40","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0003-4975(02)04285-6","article-title":"Low-dose oral amiodarone prophylaxis reduces atrial fibrillation after pulmonary resection","volume":"75","author":"Lanza","year":"2003","journal-title":"Ann Thorac Surg"},{"issue":"1","key":"10.1016\/j.chest.2016.08.1476_bib41","first-page":"91","article-title":"CCS Atrial Fibrillation Guidelines Committee. Canadian Cardiovascular Society atrial fibrillation guidelines 2010: prevention and treatment of atrial fibrillation following cardiac surgery","volume":"27","author":"Mitchell","year":"2011","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.chest.2016.08.1476_bib42","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1749-8090-4-8","article-title":"Magnesium sulphate and amiodarone prophylaxis for prevention of postoperative arrhythmia in coronary bypass operations","volume":"4","author":"Tiryakioglu","year":"2009","journal-title":"J\u00a0Cardiothorac Surg"},{"issue":"18","key":"10.1016\/j.chest.2016.08.1476_bib43","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1056\/NEJMoa1507750","article-title":"Perioperative rosuvastatin in cardiac surgery","volume":"374","author":"Zheng","year":"2016","journal-title":"N\u00a0Engl J Med"},{"issue":"3","key":"10.1016\/j.chest.2016.08.1476_bib44","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.amjcard.2013.10.020","article-title":"Meta-analysis comparing carvedilol vs\u00a0metoprolol for the prevention of postoperative atrial fibrillation following coronary artery bypass grafting","volume":"113","author":"DiNicolantonio","year":"2014","journal-title":"Am J Cardiol"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216593465?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369216593465?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T07:32:11Z","timestamp":1757921531000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369216593465"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["S0012369216593465"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2016.08.1476","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prophylaxis Against Atrial Fibrillation After General Thoracic Surgery","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2016.08.1476","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}