{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:44:11Z","timestamp":1790664251359,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.chest.2018.03.008","type":"journal-article","created":{"date-parts":[[2018,3,18]],"date-time":"2018-03-18T13:49:29Z","timestamp":1521380969000},"page":"1405-1415","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":57,"title":["Treatment of Gastroesophageal Reflux in Patients With Idiopathic Pulmonary Fibrosis"],"prefix":"10.1016","volume":"153","author":[{"given":"Lee","family":"Fidler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Sitzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane","family":"Shapera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakesh S.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.chest.2018.03.008_bib1","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1164\/rccm.201006-0894CI","article-title":"Clinical course and prediction of survival in idiopathic pulmonary fibrosis","volume":"183","author":"Ley","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"10.1016\/j.chest.2018.03.008_bib2","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1164\/ajrccm.158.6.9804105","article-title":"Increased prevalence of gastroesophageal reflux in patients with idiopathic pulmonary fibrosis","volume":"158","author":"Tobin","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"10.1016\/j.chest.2018.03.008_bib3","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1183\/09031936.00101212","article-title":"Gastro-oesophageal reflux and gastric aspiration in idiopathic pulmonary fibrosis patients","volume":"42","author":"Savarino","year":"2013","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.chest.2018.03.008_bib4","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1183\/09031936.00050911","article-title":"Bronchoalveolar lavage pepsin in acute exacerbation of idiopathic pulmonary fibrosis","volume":"39","author":"Lee","year":"2012","journal-title":"Eur Respir J"},{"issue":"6","key":"10.1016\/j.chest.2018.03.008_bib5","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1164\/rccm.2009-040GL","article-title":"An official ATS\/ERS\/JRS\/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management","volume":"183","author":"Raghu","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.chest.2018.03.008_bib6","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1164\/rccm.201506-1063ST","article-title":"An official ATS\/ERS\/JRS\/ALAT clinical practice guideline: treatment of idiopathic pulmonary fibrosis: an update of the 2011 clinical practice guideline","volume":"192","author":"Raghu","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"10.1016\/j.chest.2018.03.008_bib7","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.jtcvs.2005.10.014","article-title":"Laparoscopic fundoplication in patients with end-stage lung disease awaiting transplantation","volume":"131","author":"Linden","year":"2006","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"issue":"12","key":"10.1016\/j.chest.2018.03.008_bib8","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1111\/j.1365-2036.2007.03333.x","article-title":"Review article: the role of surgery in gastro-oesophageal reflux disease","volume":"25","author":"Vakil","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"issue":"7","key":"10.1016\/j.chest.2018.03.008_bib9","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S2213-2600(17)30219-9","article-title":"Antacid therapy in idiopathic pulmonary fibrosis: more questions than answers?","volume":"5","author":"Johannson","year":"2017","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.chest.2018.03.008_bib10","unstructured":"Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions, version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. http:\/\/handbook.cochrane.org. Accessed September 19, 2017."},{"key":"10.1016\/j.chest.2018.03.008_bib11","unstructured":"Wells GA, Shea B, O\u2019Connell D, et\u00a0al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses. www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp. Accessed September 19, 2017."},{"issue":"5","key":"10.1016\/j.chest.2018.03.008_bib12","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S2213-2600(13)70105-X","article-title":"Anti-acid treatment and disease progression in idiopathic pulmonary fibrosis: an analysis of data from three randomized controlled trials","volume":"1","author":"Lee","year":"2013","journal-title":"Lancet Respir Med"},{"issue":"5","key":"10.1016\/j.chest.2018.03.008_bib13","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/S2213-2600(16)00067-9","article-title":"Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis","volume":"4","author":"Kreuter","year":"2016","journal-title":"Lancet Respir Med"},{"issue":"6","key":"10.1016\/j.chest.2018.03.008_bib14","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1159\/000468546","article-title":"Antacid therapy and disease progression in patients with idiopathic pulmonary fibrosis who received pirfenidone","volume":"93","author":"Kreuter","year":"2017","journal-title":"Respiration"},{"issue":"3","key":"10.1016\/j.chest.2018.03.008_bib15","doi-asserted-by":"crossref","first-page":"444","DOI":"10.5056\/jnm15192","article-title":"Protective effect of proton pump inhibitor for survival in patients with gastroesophageal reflux disease and idiopathic pulmonary fibrosis","volume":"22","author":"Lee","year":"2016","journal-title":"J\u00a0Neurogastroenterol Motil"},{"issue":"3","key":"10.1016\/j.chest.2018.03.008_bib16","doi-asserted-by":"crossref","first-page":"e0151425","DOI":"10.1371\/journal.pone.0151425","article-title":"Impact of comorbidities on mortality in patients with idiopathic pulmonary fibrosis","volume":"11","author":"Kreuter","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.chest.2018.03.008_bib17","first-page":"5805","article-title":"Chronic use of anti-reflux therapy improves survival of patients with pulmonary fibrosis","volume":"10","author":"Liu","year":"2017","journal-title":"Int J Clin Exp Med"},{"issue":"12","key":"10.1016\/j.chest.2018.03.008_bib18","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1164\/rccm.201101-0138OC","article-title":"Gastroesophageal reflux therapy is associated with longer survival in patients with idiopathic pulmonary fibrosis","volume":"184","author":"Lee","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.chest.2018.03.008_bib19","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1186\/s12967-015-0614-x","article-title":"Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis","volume":"13","author":"Ghebremariam","year":"2015","journal-title":"J\u00a0Transl Med"},{"issue":"4","key":"10.1016\/j.chest.2018.03.008_bib20","article-title":"Effect of acid suppression therapy on gastroesophageal reflux and cough in idiopathic pulmonary fibrosis: an intervention study","volume":"10","author":"Kilduff","year":"2014","journal-title":"Cough"},{"issue":"2","key":"10.1016\/j.chest.2018.03.008_bib21","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1183\/09031936.00099910","article-title":"Prevalence of hiatal hernia by blinded multidetector CT in patients with idiopathic pulmonary fibrosis","volume":"39","author":"Noth","year":"2012","journal-title":"Eur Respir J"},{"issue":"3","key":"10.1016\/j.chest.2018.03.008_bib22","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1378\/chest.129.3.794","article-title":"Sole treatment of acid gastroesophageal reflux in idiopathic pulmonary fibrosis: a case series","volume":"129","author":"Raghu","year":"2006","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.chest.2018.03.008_bib23","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1183\/13993003.00488-2016","article-title":"Laparoscopic anti-reflux surgery for idiopathic pulmonary fibrosis at a single centre","volume":"48","author":"Raghu","year":"2016","journal-title":"Eur Respir J"},{"issue":"suppl 59","key":"10.1016\/j.chest.2018.03.008_bib24","first-page":"OA4502","article-title":"Effect of anti-acid medication on reduction in FVC decline with nintedanib [abstract]","volume":"46","author":"Raghu","year":"2015","journal-title":"Eur Respir J"},{"key":"10.1016\/j.chest.2018.03.008_bib25","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.rmed.2016.04.010","article-title":"A\u00a0bundled care approach to patients with idiopathic pulmonary fibrosis improves transplant-free survival","volume":"115","author":"Kulkami","year":"2016","journal-title":"Respir Med"},{"issue":"4","key":"10.1016\/j.chest.2018.03.008_bib26","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1111\/resp.12781","article-title":"Cardiovascular and antacid treatment and mortality in oxygen-dependent pulmonary fibrosis: a population-based longitudinal study","volume":"21","author":"Ekstrom","year":"2016","journal-title":"Respirology"},{"issue":"2","key":"10.1016\/j.chest.2018.03.008_bib27","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1590\/S0004-28032011000200002","article-title":"Interstitial lung disease and gastroesophageal reflux disease: key role of esophageal function tests in the diagnosis and treatment","volume":"48","author":"Soares","year":"2011","journal-title":"Arq Gastroenterol"},{"issue":"11-12","key":"10.1016\/j.chest.2018.03.008_bib28","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1111\/j.1365-2036.2011.04870.x","article-title":"Systematic review: the relationship between interstitial lung disease and gastro-esophageal reflux disease 2011","volume":"34","author":"Hershcovici","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"issue":"9","key":"10.1016\/j.chest.2018.03.008_bib29","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1001\/archsurg.2011.216","article-title":"Antireflux surgery preserves lung function in patients with gastroesophageal reflux disease and end-stage lung disease before and after lung transplantation","volume":"146","author":"Hoppo","year":"2011","journal-title":"Arch Surg"},{"issue":"22","key":"10.1016\/j.chest.2018.03.008_bib30","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1056\/NEJMoa1402582","article-title":"A\u00a0phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis","volume":"370","author":"King","year":"2014","journal-title":"N\u00a0Engl J Med"},{"issue":"22","key":"10.1016\/j.chest.2018.03.008_bib31","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.1056\/NEJMoa1402584","article-title":"Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis","volume":"370","author":"Richeldi","year":"2014","journal-title":"N\u00a0Engl J Med"},{"issue":"3","key":"10.1016\/j.chest.2018.03.008_bib32","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1164\/rccm.201604-0801CI","article-title":"Acute exacerbation of idiopathic pulmonary fibrosis: an international working group report","volume":"194","author":"Collard","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.chest.2018.03.008_bib33","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1097\/BOR.0000000000000291","article-title":"Proton pump inhibitors and osteoporosis","volume":"28","author":"Andersen","year":"2016","journal-title":"Curr Opin Rheumatol"},{"issue":"12","key":"10.1016\/j.chest.2018.03.008_bib34","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1017\/ice.2016.194","article-title":"Assessing the risk of hospital-acquired Clostridium difficile infection with proton pump inhibitor use: a meta-analysis","volume":"37","author":"Arriola","year":"2016","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"7","key":"10.1016\/j.chest.2018.03.008_bib35","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.3109\/0886022X.2015.1057800","article-title":"Proton pump inhibitors linked to hypomagnesemia: a systematic review\u00a0and meta-analysis of observational studies","volume":"37","author":"Cheungpasitporn","year":"2015","journal-title":"Ren Fail"},{"issue":"3","key":"10.1016\/j.chest.2018.03.008_bib36","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/pds.1357","article-title":"Immortal time bias in observational studies of drug effects","volume":"16","author":"Suissa","year":"2007","journal-title":"Pharmacoepidemiol Drug Saf"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001236921830415X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001236921830415X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T08:01:13Z","timestamp":1757923273000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001236921830415X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["S001236921830415X"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2018.03.008","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatment of Gastroesophageal Reflux in Patients With Idiopathic Pulmonary Fibrosis","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2018.03.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}