{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T12:34:33Z","timestamp":1761309273227,"version":"3.44.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.chest.2019.04.133","type":"journal-article","created":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T04:17:46Z","timestamp":1559017066000},"page":"659-666","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Altered Viscosity of Nasal Secretions in Postnasal Drip"],"prefix":"10.1016","volume":"156","author":[{"given":"Sarina","family":"Bucher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Schmid-Grendelmeier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael B.","family":"Soyka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.chest.2019.04.133_bib1","series-title":"Appendix. Post nasal catarrh. In: On Winter Cough, Catarrh, Bronchitis. 1st ed","first-page":"172","author":"Dobell","year":"1866"},{"issue":"2","key":"10.1016\/j.chest.2019.04.133_bib2","doi-asserted-by":"crossref","first-page":"129","DOI":"10.4193\/Rhino14.210","article-title":"Simulated postnasal mucus fails to reproduce the symptoms of postnasal drip in rhinitics but only in healthy subjects","volume":"53","author":"Rimmer","year":"2015","journal-title":"Rhinology"},{"issue":"1","key":"10.1016\/j.chest.2019.04.133_bib3","first-page":"33","article-title":"Basic concepts of mucus rheology","volume":"9","author":"Litt","year":"1973","journal-title":"Bull Physiopathol Respir (Nancy)"},{"issue":"13","key":"10.1016\/j.chest.2019.04.133_bib4","first-page":"3080","article-title":"Viscoelastic properties of airway mucus","volume":"39","author":"King","year":"1980","journal-title":"Fed Proc"},{"issue":"2","key":"10.1016\/j.chest.2019.04.133_bib5","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1164\/ajrccm.160.2.9805117","article-title":"Effect of biochemical components on rheologic properties of nasal mucus in chronic sinusitis","volume":"160","author":"Majima","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"10.1016\/j.chest.2019.04.133_bib6","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/BF00178275","article-title":"The rheological characteristics of nasal mucus in patients with rhinitis","volume":"252","author":"Pass\u00e0li","year":"1995","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"1","key":"10.1016\/j.chest.2019.04.133_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2500\/ajra.2010.24.3420","article-title":"Rheologic properties of sinonasal mucus in patients with chronic sinusitis","volume":"24","author":"Saito","year":"2010","journal-title":"Am J Rhinol Allergy"},{"issue":"1","key":"10.1016\/j.chest.2019.04.133_bib8","first-page":"22","article-title":"The rheological factor in mucociliary clearance","volume":"88","author":"Adler","year":"1976","journal-title":"J\u00a0Lab Clin Med"},{"issue":"4","key":"10.1016\/j.chest.2019.04.133_bib9","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1378\/chest.12-1183","article-title":"Aging, diabetes, and hypertension are associated with decreased nasal mucociliary clearance","volume":"143","author":"De Oliveira-Maul","year":"2013","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.chest.2019.04.133_bib10","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.resp.2010.01.013","article-title":"Furosemide impairs nasal mucociliary clearance in humans","volume":"170","author":"Goto","year":"2010","journal-title":"Respir Physiol Neurobiol"},{"issue":"5","key":"10.1016\/j.chest.2019.04.133_bib11","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1017\/S0022215100099631","article-title":"Nasal mucus clearance","volume":"100","author":"Golhar","year":"1986","journal-title":"J\u00a0Laryngol Otol"},{"issue":"4","key":"10.1016\/j.chest.2019.04.133_bib12","first-page":"107","article-title":"Volatile anesthetics and mucociliary clearance","volume":"74","author":"Kesimci","year":"2008","journal-title":"Minerva Anestesiol"},{"issue":"3","key":"10.1016\/j.chest.2019.04.133_bib13","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/S0091-6749(95)70172-9","article-title":"Atopy patch test with different vehicles and allergen concentrations: an approach to standardization","volume":"95","author":"Darsow","year":"1995","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.chest.2019.04.133_bib14","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1164\/ajrccm\/136.2.353","article-title":"Viscosity and spinability of nasal secretions induced by different provocation tests","volume":"136","author":"Brofeldt","year":"1987","journal-title":"Am Rev Respir Dis"},{"issue":"2","key":"10.1016\/j.chest.2019.04.133_bib15","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.addr.2008.09.012","article-title":"Micro- and macrorheology of mucus","volume":"61","author":"Lai","year":"2009","journal-title":"Adv Drug Deliv Rev"},{"issue":"2","key":"10.1016\/j.chest.2019.04.133_bib16","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.chest.2018.03.005","article-title":"Cystic fibrosis sputum rheology correlates with both acute and longitudinal changes in lung\u00a0function","volume":"154","author":"Ma","year":"2018","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.chest.2019.04.133_bib17","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1164\/ajrccm.155.6.9196110","article-title":"Effect of clarithromycin on nasal mucus properties in healthy subjects and in patients with purulent rhinitis","volume":"155","author":"Rubin","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"issue":"7","key":"10.1016\/j.chest.2019.04.133_bib18","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1172\/JCI106624","article-title":"Deposition and clearance of 2 micron particles in the tracheobronchial tree of normal subjects--smokers and nonsmokers","volume":"50","author":"Louren\u00e7o","year":"1971","journal-title":"J\u00a0Clin Invest"},{"issue":"4","key":"10.1016\/j.chest.2019.04.133_bib19","doi-asserted-by":"crossref","first-page":"2772","DOI":"10.1378\/chest.128.4.2772","article-title":"Mucociliary clearance is impaired in acutely ill patients","volume":"128","author":"Nakagawa","year":"2005","journal-title":"Chest"},{"issue":"4","key":"10.1016\/j.chest.2019.04.133_bib20","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.anai.2011.07.010","article-title":"Neuropeptide levels in nasal secretions from patients with and without chronic cough","volume":"107","author":"Lim","year":"2011","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"4","key":"10.1016\/j.chest.2019.04.133_bib21","doi-asserted-by":"crossref","first-page":"387","DOI":"10.4193\/Rhino11.055","article-title":"Catarrh - the patient experience","volume":"49","author":"Cathcart","year":"2011","journal-title":"Rhinology"},{"issue":"4","key":"10.1016\/j.chest.2019.04.133_bib22","doi-asserted-by":"crossref","first-page":"453","DOI":"10.4193\/Rhino11.089","article-title":"The menthol and cold sensation receptor TRPM8 in\u00a0normal human nasal mucosa and\u00a0rhinitis","volume":"49","author":"Keh","year":"2011","journal-title":"Rhinology"},{"issue":"3","key":"10.1016\/j.chest.2019.04.133_bib23","doi-asserted-by":"crossref","first-page":"227","DOI":"10.4193\/Rhino.11.152","article-title":"Up-date on neuro-immune mechanisms involved in allergic and non-allergic rhinitis","volume":"50","author":"Van Gerven","year":"2012","journal-title":"Rhinology"},{"issue":"9","key":"10.1016\/j.chest.2019.04.133_bib24","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1097\/MLG.0b013e3180ca7846","article-title":"Neuronal markers in allergic rhinitis: expression and correlation with sensory testing","volume":"117","author":"O\u2019Hanlon","year":"2007","journal-title":"Laryngoscope"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369219311225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369219311225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T08:11:13Z","timestamp":1757923873000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369219311225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S0012369219311225"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2019.04.133","relation":{},"ISSN":["0012-3692"],"issn-type":[{"type":"print","value":"0012-3692"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Altered Viscosity of Nasal Secretions in Postnasal Drip","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2019.04.133","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}