{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:31:09Z","timestamp":1789230669435,"version":"build-2803163510"},"reference-count":73,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.chest.2019.05.009","type":"journal-article","created":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T08:27:28Z","timestamp":1558513648000},"page":"579-593","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"title":["Common Variable Immune Deficiency and\u00a0Associated Complications"],"prefix":"10.1016","volume":"156","author":[{"given":"Siddhi","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debendra","family":"Pattanaik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guha","family":"Krishnaswamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jaip.2015.07.025","article-title":"International Consensus Document (ICON): common variable immunodeficiency disorders","volume":"4","author":"Bonilla","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib2","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.iac.2015.07.009","article-title":"Common variable immunodeficiency: diagnosis, management, and treatment","volume":"35","author":"Abbott","year":"2015","journal-title":"Immunol Allergy Clin North Am"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1182\/blood-2010-01-254417","article-title":"How I treat common variable immune deficiency","volume":"116","author":"Cunningham-Rundles","year":"2010","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib4","doi-asserted-by":"crossref","first-page":"21","DOI":"10.2174\/187152912801823084","article-title":"Malignancy in common variable immune deficiency: report of two rare cases of gastrointestinal malignancy and a review of the literature","volume":"12","author":"Watkins","year":"2012","journal-title":"Cardiovasc Hematol Disord Drug Targets"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib5","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1007\/s12098-016-2038-x","article-title":"Common variable immunodeficiency","volume":"83","author":"Saikia","year":"2016","journal-title":"Indian J Pediatr"},{"key":"10.1016\/j.chest.2019.05.009_bib6","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1182\/asheducation.V2012.1.301.3798316","article-title":"The many faces of common variable immunodeficiency","volume":"2012","author":"Cunningham-Rundles","year":"2012","journal-title":"Hematology Am Soc Hematol Educ Prog"},{"issue":"8","key":"10.1016\/j.chest.2019.05.009_bib7","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s10875-015-0198-5","article-title":"The 2015 IUIS Phenotypic Classification for Primary Immunodeficiencies","volume":"35","author":"Bousfiha","year":"2015","journal-title":"J\u00a0Clin Immunol"},{"issue":"3 Suppl","key":"10.1016\/j.chest.2019.05.009_bib8","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.jaci.2012.07.002","article-title":"Use and interpretation of diagnostic vaccination in primary immunodeficiency: a working group report of the Basic and Clinical Immunology Interest Section of the American Academy of Allergy, Asthma & Immunology","volume":"130","author":"Orange","year":"2012","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib9","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s12016-017-8645-0","article-title":"Review: diagnosing common variable immunodeficiency disorder in the era of genome sequencing","volume":"54","author":"Ameratunga","year":"2018","journal-title":"Clin Rev Allergy Immunol"},{"key":"10.1016\/j.chest.2019.05.009_bib10","doi-asserted-by":"crossref","first-page":"415","DOI":"10.3389\/fimmu.2014.00415","article-title":"Comparison of diagnostic criteria for common variable immunodeficiency disorder","volume":"5","author":"Ameratunga","year":"2014","journal-title":"Front Immunol"},{"key":"10.1016\/j.chest.2019.05.009_bib11","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3389\/fimmu.2014.00410","article-title":"Diagnostic immunization with bacteriophage PhiX 174 in patients with common variable immunodeficiency\/hypogammaglobulinemia","volume":"5","author":"Smith","year":"2014","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.chest.2019.05.009_bib12","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s10875-017-0406-6","article-title":"The use of Salmonella typhim vaccine to diagnose antibody deficiency","volume":"37","author":"Bausch-Jurken","year":"2017","journal-title":"J\u00a0Clin Immunol"},{"key":"10.1016\/j.chest.2019.05.009_bib13","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1476-7961-6-5","article-title":"X-linked agammaglobulinemia diagnosed late in life: case report and review of the literature","volume":"6","author":"Sigmon","year":"2008","journal-title":"Clin Mol Allergy"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.anai.2018.08.004","article-title":"Paraproteinemia and serum protein electrophoresis interpretation","volume":"122","author":"Raj","year":"2019","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"10","key":"10.1016\/j.chest.2019.05.009_bib15","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.autrev.2014.08.036","article-title":"Profound symptomatic hypogammaglobulinemia: a rare late complication after rituximab treatment for immune thrombocytopenia. Report of 3 cases and systematic review of the literature","volume":"13","author":"Levy","year":"2014","journal-title":"Autoimmun Rev"},{"key":"10.1016\/j.chest.2019.05.009_bib16","doi-asserted-by":"crossref","first-page":"626","DOI":"10.3389\/fimmu.2014.00626","article-title":"Immunoglobulin replacement therapy in secondary hypogammaglobulinemia","volume":"5","author":"Compagno","year":"2014","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.chest.2019.05.009_bib17","doi-asserted-by":"crossref","first-page":"208","DOI":"10.5692\/clinicalneurol.cn-000984","article-title":"Thymoma with immunodeficiency\/Good syndrome associated with myasthenia gravis","volume":"57","author":"Takai","year":"2017","journal-title":"Rinsho Shinkeigaku"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib18","first-page":"56","article-title":"Case report and literature review on Good's syndrome, a form of acquired immunodeficiency associated with thymomas","volume":"72","author":"Joven","year":"2013","journal-title":"Hawaii J Med Public Health"},{"issue":"Suppl 3","key":"10.1016\/j.chest.2019.05.009_bib19","doi-asserted-by":"crossref","first-page":"3056","DOI":"10.1111\/trf.15020","article-title":"Humoral immunodeficiencies: conferred risk of infections and benefits of immunoglobulin replacement therapy","volume":"58","author":"Gernez","year":"2018","journal-title":"Transfusion"},{"key":"10.1016\/j.chest.2019.05.009_bib20","doi-asserted-by":"crossref","first-page":"586","DOI":"10.3389\/fimmu.2017.00586","article-title":"Specific antibody deficiency: controversies in diagnosis and management","volume":"8","author":"Perez","year":"2017","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.chest.2019.05.009_bib21","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.humimm.2018.10.015","article-title":"Primary B-cell immunodeficiencies","volume":"80","author":"Smith","year":"2019","journal-title":"Hum Immunol"},{"issue":"6","key":"10.1016\/j.chest.2019.05.009_bib22","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1016\/j.jaci.2011.02.039","article-title":"Genome-wide association identifies diverse causes of common variable immunodeficiency","volume":"127","author":"Orange","year":"2011","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"3","key":"10.1016\/j.chest.2019.05.009_bib23","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/cei.12947","article-title":"The role of genomics in common variable immunodeficiency disorders","volume":"188","author":"Kienzler","year":"2017","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.chest.2019.05.009_bib24","doi-asserted-by":"crossref","first-page":"2130","DOI":"10.3389\/fimmu.2018.02130","article-title":"Assessing disease severity in common variable immunodeficiency disorders (CVID) and CVID-like disorders","volume":"9","author":"Ameratunga","year":"2018","journal-title":"Front Immunol"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib25","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/iji.12217","article-title":"Genetics of common variable immunodeficiency: role of transmembrane activator and calcium modulator and cyclophilin ligand interactor","volume":"42","author":"Sathkumara","year":"2015","journal-title":"Int J Immunogenet"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib26","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/cei.12178","article-title":"New diagnostic criteria for common variable immune deficiency (CVID), which may assist with decisions to treat with intravenous or subcutaneous immunoglobulin","volume":"174","author":"Ameratunga","year":"2013","journal-title":"Clin Exp Immunol"},{"issue":"11","key":"10.1016\/j.chest.2019.05.009_bib27","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1056\/NEJMoa1512234","article-title":"Loss of B cells in patients with heterozygous mutations in IKAROS","volume":"374","author":"Kuehn","year":"2016","journal-title":"N\u00a0Engl J Med"},{"issue":"9","key":"10.1016\/j.chest.2019.05.009_bib28","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.cgh.2013.02.024","article-title":"Diagnosis and treatment of gastrointestinal disorders in patients with primary immunodeficiency","volume":"11","author":"Agarwal","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"issue":"3","key":"10.1016\/j.chest.2019.05.009_bib29","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/s12016-017-8638-z","article-title":"Common variable immunodeficiency and liver involvement","volume":"55","author":"Song","year":"2018","journal-title":"Clin Rev Allergy Immunol"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib30","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1007\/s10875-013-9873-6","article-title":"Nodular regenerative hyperplasia in common variable immunodeficiency","volume":"33","author":"Fuss","year":"2013","journal-title":"J\u00a0Clin Immunol"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib31","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.semarthrit.2018.02.013","article-title":"Phenotypic characterization of patients with rheumatologic manifestations of common variable immunodeficiency","volume":"48","author":"Gutierrez","year":"2018","journal-title":"Semin Arthritis Rheum"},{"issue":"5","key":"10.1016\/j.chest.2019.05.009_bib32","doi-asserted-by":"crossref","DOI":"10.1111\/sji.12663","article-title":"Rheumatologic complications in a cohort of 227 patients with common variable immunodeficiency","volume":"87","author":"Azizi","year":"2018","journal-title":"Scand J Immunol"},{"issue":"9","key":"10.1016\/j.chest.2019.05.009_bib33","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.autrev.2016.07.011","article-title":"Autoimmunity and infection in common variable immunodeficiency (CVID)","volume":"15","author":"Patuzzo","year":"2016","journal-title":"Autoimmun Rev"},{"issue":"3","key":"10.1016\/j.chest.2019.05.009_bib34","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s11882-016-0597-6","article-title":"Autoimmune and lymphoproliferative complications of common variable immunodeficiency","volume":"16","author":"Maglione","year":"2016","journal-title":"Curr Allergy Asthma Rep"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib35","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.jaci.2013.12.1077","article-title":"Clinical picture and treatment of 2212 patients with common variable immunodeficiency","volume":"134","author":"Gathmann","year":"2014","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"7","key":"10.1016\/j.chest.2019.05.009_bib36","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1182\/blood-2011-09-377945","article-title":"Morbidity and mortality in common variable immune deficiency over 4 decades","volume":"119","author":"Resnick","year":"2012","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib37","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1006\/clim.1999.4725","article-title":"Common variable immunodeficiency: clinical and immunological features of 248 patients","volume":"92","author":"Cunningham-Rundles","year":"1999","journal-title":"Clin Immunol"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib38","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.iac.2015.07.004","article-title":"Pulmonary manifestations of primary immunodeficiency disorders","volume":"35","author":"Nonas","year":"2015","journal-title":"Immunol Allergy Clin North Am"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib39","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.anai.2014.04.024","article-title":"Pulmonary radiologic findings in common variable immunodeficiency: clinical and immunological correlations","volume":"113","author":"Maglione","year":"2014","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"6","key":"10.1016\/j.chest.2019.05.009_bib40","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.jaip.2016.08.005","article-title":"Lung disease in primary antibody deficiencies","volume":"4","author":"Schussler","year":"2016","journal-title":"J\u00a0Allergy Clin Immunol Pract"},{"issue":"149","key":"10.1016\/j.chest.2019.05.009_bib41","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0019-2018","article-title":"The broad spectrum of lung diseases in primary antibody deficiencies","volume":"27","author":"Cinetto","year":"2018","journal-title":"Eur Respir Rev"},{"issue":"8","key":"10.1016\/j.chest.2019.05.009_bib42","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/S2213-2600(15)00202-7","article-title":"Lung disease in primary antibody deficiency","volume":"3","author":"Verma","year":"2015","journal-title":"Lancet Respir Med"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib43","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s10875-018-0577-9","article-title":"Imaging of bronchial pathology in antibody deficiency: data from the European Chest CT Group","volume":"39","author":"Schutz","year":"2019","journal-title":"J\u00a0Clin Immunol"},{"key":"10.1016\/j.chest.2019.05.009_bib44","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.3389\/fimmu.2018.01837","article-title":"The lung in primary immunodeficiencies: new concepts in infection and inflammation","volume":"9","author":"Baumann","year":"2018","journal-title":"Front Immunol"},{"issue":"6","key":"10.1016\/j.chest.2019.05.009_bib45","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1097\/MOP.0000000000000697","article-title":"The overlap between allergy and immunodeficiency","volume":"30","author":"Sokol","year":"2018","journal-title":"Curr Opin Pediatr"},{"issue":"3","key":"10.1016\/j.chest.2019.05.009_bib46","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/s10875-018-0488-9","article-title":"Immunologist's perspectives on assessment and management of lung disease in CVID: a survey of the membership of the Clinical Immunology Society and the European Society for Immunodeficiencies","volume":"38","author":"Akhter","year":"2018","journal-title":"J\u00a0Clin Immunol"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib47","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s10875-015-0151-7","article-title":"Common variable immunodeficiency and pulmonary amyloidosis: a case report","volume":"35","author":"Arslan","year":"2015","journal-title":"J\u00a0Clin Immunol"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib48","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.anai.2017.09.075","article-title":"Allergic disease in patients with common variable immunodeficiency at a tertiary care referral center","volume":"120","author":"Bjelac","year":"2018","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib49","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.clim.2009.05.001","article-title":"Granulomatous disease in common variable immunodeficiency","volume":"133","author":"Ardeniz","year":"2009","journal-title":"Clin Immunol"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib50","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/crj.12511","article-title":"Granulomatous-lymphocytic interstitial lung disease as the first manifestation of common variable immunodeficiency","volume":"12","author":"Tashtoush","year":"2018","journal-title":"Clin Respir J"},{"issue":"6","key":"10.1016\/j.chest.2019.05.009_bib51","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/RTI.0000000000000350","article-title":"Pulmonary manifestations of common variable immunodeficiency","volume":"33","author":"Bang","year":"2018","journal-title":"J\u00a0Thorac Imaging"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib52","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.jaci.2004.05.057","article-title":"Granulomatous-lymphocytic lung disease shortens survival in common variable immunodeficiency","volume":"114","author":"Bates","year":"2004","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib53","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.clim.2009.10.002","article-title":"Granulomatous-lymphocytic interstitial lung disease (GLILD) in common variable immunodeficiency (CVID)","volume":"134","author":"Park","year":"2010","journal-title":"Clin Immunol"},{"issue":"5","key":"10.1016\/j.chest.2019.05.009_bib54","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.jaci.2005.08.041","article-title":"Caseating granulomatous disease in common variable immunodeficiency treated with infliximab","volume":"116","author":"Hatab","year":"2005","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib55","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1378\/chest.100.2.552","article-title":"Bronchiolitis obliterans organizing pneumonia in common variable immunodeficiency syndrome","volume":"100","author":"Kaufman","year":"1991","journal-title":"Chest"},{"issue":"3","key":"10.1016\/j.chest.2019.05.009_bib56","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1055\/s-0034-1376862","article-title":"Sarcoidosis and common variable immunodeficiency: similarities and differences","volume":"35","author":"Verbsky","year":"2014","journal-title":"Semin Respir Crit Care Med"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib57","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1054\/blre.2001.0185","article-title":"Hematologic complications of primary immune deficiencies","volume":"16","author":"Cunningham-Rundles","year":"2002","journal-title":"Blood Rev"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib58","doi-asserted-by":"crossref","first-page":"525","DOI":"10.5858\/arpa.2017-0372-RS","article-title":"Gastrointestinal presentations of common variable immunodeficiency: hiding in plain sight","volume":"43","author":"Odetola","year":"2019","journal-title":"Arch Pathol Lab Med"},{"issue":"11","key":"10.1016\/j.chest.2019.05.009_bib59","doi-asserted-by":"crossref","first-page":"534","DOI":"10.4253\/wjge.v6.i11.534","article-title":"Nodular lymphoid hyperplasia in the gastrointestinal tract in adult patients: a review","volume":"6","author":"Albuquerque","year":"2014","journal-title":"World J Gastrointest Endosc"},{"issue":"6","key":"10.1016\/j.chest.2019.05.009_bib60","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1097\/ACI.0000000000000218","article-title":"The autoimmune conundrum in common variable immunodeficiency disorders","volume":"15","author":"van de Ven","year":"2015","journal-title":"Curr Opin Allergy Clin Immunol"},{"issue":"3","key":"10.1016\/j.chest.2019.05.009_bib61","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/cei.12915","article-title":"When to initiate immunoglobulin replacement therapy (IGRT) in antibody deficiency: a practical approach","volume":"188","author":"Jolles","year":"2017","journal-title":"Clin Exp Immunol"},{"issue":"6","key":"10.1016\/j.chest.2019.05.009_bib62","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.anai.2016.08.016","article-title":"Management of primary antibody deficiency syndromes","volume":"117","author":"Bonagura","year":"2016","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"Suppl 2","key":"10.1016\/j.chest.2019.05.009_bib63","doi-asserted-by":"crossref","first-page":"S90","DOI":"10.1007\/s10875-012-9838-1","article-title":"Using intravenous immunoglobulin (IVIG) to treat patients with primary immune deficiency disease","volume":"33","author":"Bonagura","year":"2013","journal-title":"J\u00a0Clin Immunol"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib64","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jaci.2008.04.044","article-title":"Biologic IgG level in primary immunodeficiency disease: the IgG level that protects against recurrent infection","volume":"122","author":"Bonagura","year":"2008","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"2","key":"10.1016\/j.chest.2019.05.009_bib65","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s10875-014-9990-x","article-title":"Emerging paradigm of primary immunodeficiency disease: individualizing immunoglobulin dose and delivery to enhance outcomes","volume":"37","author":"Shapiro","year":"2017","journal-title":"J\u00a0Clin Immunol"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib66","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.clim.2010.06.012","article-title":"Impact of trough IgG on pneumonia incidence in primary immunodeficiency: a meta-analysis of clinical studies","volume":"137","author":"Orange","year":"2010","journal-title":"Clin Immunol"},{"issue":"12","key":"10.1016\/j.chest.2019.05.009_bib67","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1136\/thx.2004.029819","article-title":"Lymphocytic interstitial pneumonia associated with common variable immunodeficiency resolved with intravenous immunoglobulins","volume":"61","author":"Arish","year":"2006","journal-title":"Thorax"},{"issue":"4","key":"10.1016\/j.chest.2019.05.009_bib68","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0091-6749(82)90066-5","article-title":"Common variable hypogammaglobulinemia with T-cell nodular lymphoid interstitial pneumonitis and B-cell nodular lymphoid hyperplasia:\u00a0different lymphocyte populations with a similar response to prednisone therapy","volume":"70","author":"Kohler","year":"1982","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib69","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s10875-012-9755-3","article-title":"Use of combination chemotherapy for treatment of granulomatous and lymphocytic interstitial lung disease (GLILD) in patients with common variable immunodeficiency (CVID)","volume":"33","author":"Chase","year":"2013","journal-title":"J\u00a0Clin Immunol"},{"key":"10.1016\/j.chest.2019.05.009_bib70","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2016-215624","article-title":"Management of granulomatous lymphocytic interstitial lung disease in a patient with common variable immune deficiency","volume":"2016","author":"Pathria","year":"2016","journal-title":"BMJ Case Rep"},{"issue":"5","key":"10.1016\/j.chest.2019.05.009_bib71","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/MCP.0b013e3283642c47","article-title":"Common variable immunodeficiency-associated granulomatous and interstitial lung disease","volume":"19","author":"Prasse","year":"2013","journal-title":"Curr Opin Pulm Med"},{"issue":"1","key":"10.1016\/j.chest.2019.05.009_bib72","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1136\/thorax.55.1.88","article-title":"Lymphoid interstitial pneumonitis associated with common variable hypogammaglobulinaemia treated with cyclosporin A","volume":"55","author":"Davies","year":"2000","journal-title":"Thorax"},{"issue":"11","key":"10.1016\/j.chest.2019.05.009_bib73","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s11882-017-0749-3","article-title":"Influenza vaccination in patients with common variable immunodeficiency (CVID)","volume":"17","author":"Mieves","year":"2017","journal-title":"Curr Allergy Asthma Rep"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001236921931116X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001236921931116X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T08:10:58Z","timestamp":1757923858000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001236921931116X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":73,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["S001236921931116X"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2019.05.009","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Common Variable Immune Deficiency and\u00a0Associated Complications","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2019.05.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. under license from the American College of Chest Physicians.","name":"copyright","label":"Copyright"}]}}