{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T20:25:45Z","timestamp":1792441545494,"version":"4.5.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.chest.2021.06.076","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T01:43:25Z","timestamp":1626659005000},"page":"2178-2186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":87,"title":["Neonatal Lung Ultrasound and Surfactant Administration"],"prefix":"10.1016","volume":"160","author":[{"given":"Francesco","family":"Raimondi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fiorella","family":"Migliaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iuri","family":"Corsini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Meneghin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Pierri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"Salom\u00e8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Perri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Aversa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Nobile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Lama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Varano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilena","family":"Savoia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Gatto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Leonardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Letizia","family":"Capasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virgilio Paolo","family":"Carnielli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Mosca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Dani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Vento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasquale","family":"Dolce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Lista","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.chest.2021.06.076_bib1","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1542\/peds.2013-3443","article-title":"Surfactant replacement therapy for preterm and term neonates with respiratory distress","volume":"133","author":"Polin","year":"2014","journal-title":"Pediatrics"},{"issue":"4","key":"10.1016\/j.chest.2021.06.076_bib2","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1159\/000499361","article-title":"European consensus guidelines on the management of respiratory distress syndrome\u20142019 update","volume":"115","author":"Sweet","year":"2019","journal-title":"Neonatology"},{"key":"10.1016\/j.chest.2021.06.076_bib3","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.jpeds.2016.04.018","article-title":"Lung ultrasound for diagnosing pneumothorax in the critically ill neonate","volume":"175","author":"Raimondi","year":"2016","journal-title":"J\u00a0Pediatr"},{"issue":"1","key":"10.1016\/j.chest.2021.06.076_bib4","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1159\/000493001","article-title":"Lung ultrasound for the differential diagnosis of respiratory distress in neonates","volume":"115","author":"Corsini","year":"2019","journal-title":"Neonatology"},{"issue":"3","key":"10.1016\/j.chest.2021.06.076_bib5","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1159\/000495911","article-title":"A\u00a0multicenter lung ultrasound study on transient tachypnea of the neonate","volume":"115","author":"Raimondi","year":"2019","journal-title":"Neonatology"},{"issue":"2","key":"10.1016\/j.chest.2021.06.076_bib6","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1159\/000358227","article-title":"Lung ultrasound accuracy in respiratory distress syndrome and transient tachypnea of the newborn","volume":"106","author":"Vergine","year":"2014","journal-title":"Neonatology"},{"issue":"2","key":"10.1016\/j.chest.2021.06.076_bib7","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1136\/archdischild-2019-316832","article-title":"Neonatal lung ultrasonography to evaluate need for surfactant or mechanical ventilation: a systematic review and meta-analysis","volume":"105","author":"Razak","year":"2020","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"8","key":"10.1016\/j.chest.2021.06.076_bib8","doi-asserted-by":"crossref","first-page":"W163","DOI":"10.7326\/0003-4819-147-8-200710160-00010-w1","article-title":"Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration","volume":"147","author":"Vandenbroucke","year":"2007","journal-title":"Ann Intern Med"},{"issue":"8","key":"10.1016\/j.chest.2021.06.076_bib9","doi-asserted-by":"crossref","DOI":"10.1001\/jamapediatrics.2015.1797","article-title":"Lung ultrasonography score to evaluate oxygenation and surfactant need in neonates treated with continuous positive airway pressure","volume":"169","author":"Brat","year":"2015","journal-title":"JAMA Pediatr"},{"key":"10.1016\/j.chest.2021.06.076_bib10","doi-asserted-by":"crossref","unstructured":"Raimondi F, Migliaro F, Corsini I, et al. Lung ultrasound score progress in neonatal respiratory distress syndrome. Pediatrics. 2021;147(4):e2020030528.","DOI":"10.1542\/peds.2020-030528"},{"issue":"10","key":"10.1016\/j.chest.2021.06.076_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0202397","article-title":"Visual assessment versus computer-assisted gray scale analysis in the ultrasound evaluation of neonatal respiratory status","volume":"13","author":"Raimondi","year":"2018","journal-title":"PLOS One"},{"issue":"7","key":"10.1016\/j.chest.2021.06.076_bib12","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1002\/ppul.24792","article-title":"Lung ultrasound in the neonatal intensive care unit: review of the literature and future perspectives","volume":"55","author":"Corsini","year":"2020","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.chest.2021.06.076_bib13","doi-asserted-by":"crossref","first-page":"837","DOI":"10.2307\/2531595","article-title":"Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach","volume":"44","author":"DeLong","year":"1988","journal-title":"Biometrics"},{"key":"10.1016\/j.chest.2021.06.076_bib14","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/1471-2105-12-77","article-title":"pROC: an open-source package for R and S+ to analyze and compare ROC curves","volume":"12","author":"Robin","year":"2011","journal-title":"BMC Bioinformatics"},{"issue":"2","key":"10.1016\/j.chest.2021.06.076_bib15","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/ppul.25216","article-title":"Lung ultrasound for early surfactant treatment: development and validation of a predictive model","volume":"56","author":"Aldecoa Bilbao","year":"2021","journal-title":"Pediatr Pulmonol"},{"issue":"3","key":"10.1016\/j.chest.2021.06.076_bib16","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2018-0463","article-title":"Lung ultrasound score predicts surfactant need in extremely preterm neonates","volume":"142","author":"De Martino","year":"2018","journal-title":"Pediatrics"},{"key":"10.1016\/j.chest.2021.06.076_bib17","article-title":"The role of lung ultrasound as an early diagnostic tool for need of surfactant therapy in preterm infants with respiratory distress syndrome","author":"Vardar","year":"2020","journal-title":"Am J Perinatol"},{"issue":"1","key":"10.1016\/j.chest.2021.06.076_bib18","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1007\/s00431-019-03470-0","article-title":"Lung ultrasound in preterm infants with respiratory distress: experience in a neonatal intensive care unit","volume":"179","author":"Gregorio Hernandez","year":"2020","journal-title":"Eur J Pediatr"},{"issue":"6","key":"10.1016\/j.chest.2021.06.076_bib19","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1055\/s-0039-1700856","article-title":"Evaluation of different types of natural surfactants by lung ultrasound in respiratory distress syndrome","volume":"38","author":"Bozkaya","year":"2021","journal-title":"Am J Perinatol"},{"key":"10.1016\/j.chest.2021.06.076_bib20","doi-asserted-by":"crossref","unstructured":"Perri A, Riccardi R, Iannotta R, et\u00a0al. Lung ultrasonography score versus chest X-ray score to predict surfactant administration in newborns with respiratory distress syndrome. Pediatr Pulmonol. 201853(9):1231-1236.","DOI":"10.1002\/ppul.24076"},{"issue":"3","key":"10.1016\/j.chest.2021.06.076_bib21","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1002\/ppul.1950150306","article-title":"Rapid improvement of static compliance after surfactant treatment in preterm infants with respiratory distress syndrome","volume":"15","author":"Baraldi","year":"1993","journal-title":"Pediatr Pulmonol"},{"issue":"5","key":"10.1016\/j.chest.2021.06.076_bib22","first-page":"382","article-title":"Neonatal lung function in very immature infants with and without RDS","volume":"27","author":"Kavvadia","year":"1999","journal-title":"J\u00a0Perinatal Med"},{"issue":"1","key":"10.1016\/j.chest.2021.06.076_bib23","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/ppul.24566","article-title":"Neonatal lung ultrasonography score after surfactant in preterm infants: a prospective observational study","volume":"55","author":"Perri","year":"2020","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.chest.2021.06.076_bib24","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jpeds.2019.04.020","article-title":"Echography-guided surfactant therapy to improve timeliness of surfactant replacement: a quality improvement project","volume":"212","author":"Raschetti","year":"2019","journal-title":"J\u00a0Pediatr"},{"issue":"12","key":"10.1016\/j.chest.2021.06.076_bib25","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1007\/s00431-020-03744-y","article-title":"Early surfactant replacement guided by lung ultrasound in preterm newborns with RDS: the ULTRASURF randomised controlled trial","volume":"179","author":"Rodriguez-Fanjul","year":"2020","journal-title":"Eur J Ped"},{"issue":"2","key":"10.1016\/j.chest.2021.06.076_bib26","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1159\/000513783","article-title":"Personalized medicine for the management of RDS in preterm neonates","volume":"118","author":"De Luca","year":"2021","journal-title":"Neonatology"},{"issue":"7","key":"10.1016\/j.chest.2021.06.076_bib27","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1038\/s41372-021-01039-0","article-title":"Lung ultrasound (LUS) and surfactant treatment: looking for the best predictive moment","volume":"41","author":"Kayki","year":"2021","journal-title":"J Perinatol"},{"issue":"5","key":"10.1016\/j.chest.2021.06.076_bib28","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.7269","article-title":"Association of adherence to surfactant best practice uses with clinical outcomes among neonates in Sweden","volume":"4","author":"Challis","year":"2021","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.chest.2021.06.076_bib29","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.resuscitation.2021.01.025","article-title":"Lung ultrasound immediately after birth\u00a0predicts the need for surfactant therapy in very- and extremely preterm\u00a0infants","volume":"162","author":"Badurdeen","year":"2021","journal-title":"Resuscitation"},{"issue":"5","key":"10.1016\/j.chest.2021.06.076_bib30","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.jclinepi.2008.12.011","article-title":"A\u00a0pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers","volume":"62","author":"Thorpe","year":"2009","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.chest.2021.06.076_bib31","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1007\/s00134-018-5323-5","article-title":"\u2018Lumping or splitting\u2019 in paediatric acute\u00a0respiratory distress syndrome (PARDS)","volume":"44","author":"De Luca","year":"2018","journal-title":"Intensive Care Med"},{"issue":"4","key":"10.1016\/j.chest.2021.06.076_bib32","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.chest.2019.11.013","article-title":"Effect of different probes and expertise on the interpretation reliability of point-of-care lung ultrasound","volume":"157","author":"Gomond-Le Goff","year":"2020","journal-title":"Chest"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369221013544?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369221013544?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T23:01:33Z","timestamp":1762124493000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369221013544"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["S0012369221013544"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2021.06.076","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neonatal Lung Ultrasound and Surfactant Administration","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2021.06.076","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}