{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:44:35Z","timestamp":1758055475572,"version":"3.44.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST"],"published-print":{"date-parts":[[2022,1]]},"DOI":"10.1016\/j.chest.2021.07.054","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T05:53:02Z","timestamp":1641448382000},"page":"e29-e34","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["A 65-Year-Old Man With Weight Loss, Peripheral Neuropathy, and Lower Extremity Swelling"],"prefix":"10.1016","volume":"161","author":[{"given":"Trevor","family":"Lane","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Hountras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"27","key":"10.1016\/j.chest.2021.07.054_bib1","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1056\/NEJM199212313272705","article-title":"Plasma-cell dyscrasia with polyneuropathy","volume":"327","author":"Miralles","year":"1992","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.chest.2021.07.054_bib2","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1378\/chest.07-1800","article-title":"Pulmonary manifestations in patients with POEMS syndrome: a retrospective review of 137 patients","volume":"133","author":"Allam","year":"2008","journal-title":"Chest"},{"issue":"6","key":"10.1016\/j.chest.2021.07.054_bib3","doi-asserted-by":"crossref","first-page":"464","DOI":"10.3816\/CLML.2010.n.080","article-title":"Beyond the CRAB symptoms: a study of presenting clinical manifestations of multiple myeloma","volume":"10","author":"Talamo","year":"2010","journal-title":"Clin Lymphoma Myeloma Leukemia"},{"issue":"11","key":"10.1016\/j.chest.2021.07.054_bib4","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1056\/NEJMra1011442","article-title":"Multiple myeloma","volume":"364","author":"Palumbo","year":"2011","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.chest.2021.07.054_bib5","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.ccm.2013.08.005","article-title":"World Health Organization group 5 pulmonary hypertension","volume":"34","author":"Lahm","year":"2013","journal-title":"Clin Chest Med"},{"issue":"1","key":"10.1016\/j.chest.2021.07.054_bib6","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.rmed.2014.11.005","article-title":"Pulmonary morbidity improves after autologous stem cell transplantation in POEMS syndrome","volume":"109","author":"Chandrashekaran","year":"2015","journal-title":"Resp Med"},{"issue":"11","key":"10.1016\/j.chest.2021.07.054_bib7","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2015-009157","article-title":"Vascular endothelial growth factor as a predictive marker for POEMS syndrome treatment response: retrospective cohort study","volume":"5","author":"Misawa","year":"2015","journal-title":"BMJ Open"},{"issue":"11","key":"10.1016\/j.chest.2021.07.054_bib8","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/S1474-4422(16)30157-0","article-title":"Safety and efficacy of thalidomide in patients with POEMS syndrome: a multicentre, randomised, double-blind, placebo-controlled trial","volume":"15","author":"Misawa","year":"2016","journal-title":"Lancet Neurol"},{"issue":"11","key":"10.1016\/j.chest.2021.07.054_bib9","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1007\/s11906-017-0783-5","article-title":"Medical management of pulmonary hypertension with unclear and\/or multifactorial mechanisms (group 5): is there a role for pulmonary arterial hypertension medications?","volume":"19","author":"Weatherald","year":"2017","journal-title":"Curr Hypertens Rep"},{"issue":"7","key":"10.1016\/j.chest.2021.07.054_bib10","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1002\/ajh.25495","article-title":"POEMS syndrome: 2019 update on diagnosis, risk-stratification, and management","volume":"94","author":"Dispenzieri","year":"2019","journal-title":"Am J Hematol"}],"container-title":["CHEST"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369221015051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369221015051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T08:43:22Z","timestamp":1757925802000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369221015051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["S0012369221015051"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2021.07.054","relation":{},"ISSN":["0012-3692"],"issn-type":[{"type":"print","value":"0012-3692"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A 65-Year-Old Man With Weight Loss, Peripheral Neuropathy, and Lower Extremity Swelling","name":"articletitle","label":"Article Title"},{"value":"CHEST","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2021.07.054","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}