{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:45:55Z","timestamp":1758055555861,"version":"3.44.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,10]],"date-time":"2022-06-10T00:00:00Z","timestamp":1654819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Chest"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.chest.2022.06.006","type":"journal-article","created":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T04:06:20Z","timestamp":1670299580000},"page":"e295-e299","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["A 77-Year-Old Woman With Capillary Hypoxia and Perioral Cyanosis"],"prefix":"10.1016","volume":"162","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4801-0147","authenticated-orcid":false,"given":"Daniel Z.","family":"Hodson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuliana G.","family":"Repetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel T.","family":"Hoesterey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yejoo","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kinan","family":"Bachour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9815-0864","authenticated-orcid":false,"given":"Roberto L.","family":"Mempin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tisha S.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.chest.2022.06.006_bib1","first-page":"541","article-title":"Idiopathic cyanosis due to sulph-h\u00e6moglobin\u00e6mia: enterogenous cyanosis","volume":"90","author":"West","year":"1907","journal-title":"Med Chir Trans"},{"issue":"13","key":"10.1016\/j.chest.2022.06.006_bib2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1056\/NEJM194809232391305","article-title":"Methemoglobinemia and sulfhemoglobinemia","volume":"239","author":"Finch","year":"1948","journal-title":"N\u00a0Engl J Med"},{"issue":"4","key":"10.1016\/j.chest.2022.06.006_bib3","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/0002-8703(51)90153-6","article-title":"Sulfhemoglobinemia; a study of 62 clinical cases","volume":"42","author":"Brandenburg","year":"1951","journal-title":"Am Heart J"},{"issue":"24","key":"10.1016\/j.chest.2022.06.006_bib4","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1056\/NEJM198406143102407","article-title":"Sulfhemoglobinemia","volume":"310","author":"Park","year":"1984","journal-title":"N\u00a0Engl J Med"},{"issue":"8","key":"10.1016\/j.chest.2022.06.006_bib5","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1001\/archpedi.152.8.803","article-title":"Pseudomethemoglobinemia: a case report and review of sulfhemoglobinemia","volume":"152","author":"Lu","year":"1998","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"3","key":"10.1016\/j.chest.2022.06.006_bib6","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1097\/00000542-200009000-00040","article-title":"Sulfhemoglobinemia presenting as pulse oximetry desaturation","volume":"93","author":"Aravindhan","year":"2000","journal-title":"Anesthesiology"},{"issue":"6","key":"10.1016\/j.chest.2022.06.006_bib7","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1345\/aph.1E557","article-title":"Phenazopyridine-induced sulfhemoglobinemia","volume":"39","author":"Gopalachar","year":"2005","journal-title":"Ann Pharmacother"},{"issue":"7","key":"10.1016\/j.chest.2022.06.006_bib8","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1364\/BOE.9.003284","article-title":"On the dysfunctional hemoglobins and cyanosis connection: practical implications for the clinical detection and differentiation of methemoglobinemia and sulfhemoglobinemia","volume":"9","author":"Askew","year":"2018","journal-title":"Biomed Opt Express"},{"issue":"2","key":"10.1016\/j.chest.2022.06.006_bib9","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jemermed.2021.03.002","article-title":"Case report: phenazopyridine-induced sulfhemoglobinemia in an 83-year-old presenting with dyspnea","volume":"61","author":"Morales","year":"2021","journal-title":"J\u00a0Emerg Med"},{"issue":"4","key":"10.1016\/j.chest.2022.06.006_bib10","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1111\/ijlh.13581","article-title":"Interpreting sulfhemoglobin and methemoglobin in patients with cyanosis: an overview of patients with M-hemoglobin variants","volume":"43","author":"Rangan","year":"2021","journal-title":"Int J Lab Hematol"}],"container-title":["Chest"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369222010868?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369222010868?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T08:45:15Z","timestamp":1757925915000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369222010868"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["S0012369222010868"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2022.06.006","relation":{},"ISSN":["0012-3692"],"issn-type":[{"type":"print","value":"0012-3692"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A 77-Year-Old Woman With Capillary Hypoxia and Perioral Cyanosis","name":"articletitle","label":"Article Title"},{"value":"Chest","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2022.06.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier Inc under license from the American College of Chest Physicians.","name":"copyright","label":"Copyright"}]}}