{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:57:17Z","timestamp":1792112237715,"version":"4.4.0"},"reference-count":51,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.chest.2022.12.033","type":"journal-article","created":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T15:27:26Z","timestamp":1672846046000},"page":"1425-1436","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"title":["New and Persistent Sedative Prescriptions Among Older Adults Following a Critical Illness"],"prefix":"10.1016","volume":"163","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6545-3890","authenticated-orcid":false,"given":"Lisa D.","family":"Burry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaim M.","family":"Bell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruxandra","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damon C.","family":"Scales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E.","family":"Bronskill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3360-4831","authenticated-orcid":false,"given":"David","family":"Williamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1700-3972","authenticated-orcid":false,"given":"Louise","family":"Rose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longdi","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Fowler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3971-3166","authenticated-orcid":false,"given":"Claudio M.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Dolovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Wunsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.chest.2022.12.033_bib1","doi-asserted-by":"crossref","first-page":"e825","DOI":"10.1097\/CCM.0000000000003299","article-title":"Clinical practice guidelines for the prevention and management of pain, agitation\/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU","volume":"46","author":"Devlin","year":"2018","journal-title":"Crit Care Med"},{"issue":"7","key":"10.1016\/j.chest.2022.12.033_bib2","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1007\/s12630-014-0174-1","article-title":"Analgesic, sedative, antipsychotic, and neuromuscular blocker use in Canadian intensive care units: a prospective, multicentre, observational study","volume":"61","author":"Burry","year":"2014","journal-title":"Can J Anaesth"},{"issue":"8","key":"10.1016\/j.chest.2022.12.033_bib3","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1513\/AnnalsATS.201812-913FR","article-title":"Approaches to addressing post\u2013intensive care syndrome among intensive care unit survivors. A narrative review","volume":"16","author":"Brown","year":"2019","journal-title":"Ann Am Thorac Soc"},{"issue":"7","key":"10.1016\/j.chest.2022.12.033_bib4","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1007\/s11606-007-0194-4","article-title":"Initiation of benzodiazepines in the elderly after hospitalization","volume":"22","author":"Bell","year":"2007","journal-title":"J\u00a0Gen Intern Med"},{"issue":"2","key":"10.1016\/j.chest.2022.12.033_bib5","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1007\/s11606-015-3501-5","article-title":"Unintentional continuation of medications intended for acute illness after hospital discharge: a population-based cohort study","volume":"31","author":"Scales","year":"2016","journal-title":"J\u00a0Gen Intern Med"},{"issue":"10","key":"10.1016\/j.chest.2022.12.033_bib6","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1111\/j.1532-5415.2011.03591.x","article-title":"Risk of fractures requiring hospitalization after an initial prescription for zolpidem, alprazolam, lorazepam, or diazepam in older adults","volume":"59","author":"Finkle","year":"2011","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"5","key":"10.1016\/j.chest.2022.12.033_bib7","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1001\/jamapsychiatry.2014.3018","article-title":"Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm","volume":"72","author":"Maust","year":"2015","journal-title":"JAMA Psychiatry"},{"issue":"11","key":"10.1016\/j.chest.2022.12.033_bib8","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1111\/jgs.13702","article-title":"American Geriatrics Society 2015 Updated Beers criteria for potentially inappropriate medication use in older adults","volume":"63","year":"2015","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"10","key":"10.1016\/j.chest.2022.12.033_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001885","article-title":"The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement","volume":"12","author":"Benchimol","year":"2015","journal-title":"PLoS Med"},{"issue":"2","key":"10.1016\/j.chest.2022.12.033_bib11","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1504\/IJIQ.2008.022958","article-title":"The National Ambulatory Care Reporting System: factors that affect the quality of its emergency data","volume":"2","author":"Gibson","year":"2008","journal-title":"Int J Information Quality"},{"key":"10.1016\/j.chest.2022.12.033_bib12","series-title":"The Ontario Drug Benefit Program copayment: its impact on access for Ontario seniors and charges to the program","author":"Hux","year":"1997"},{"issue":"6","key":"10.1016\/j.chest.2022.12.033_bib13","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/0735-1097(96)00018-6","article-title":"Characteristics and mortality outcomes of thrombolysis trial participants and nonparticipants: a population-based comparison","volume":"27","author":"Jha","year":"1996","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.chest.2022.12.033_bib14","series-title":"Canadian Institute for Health Information Discharge Abstract Database: A Validation Study","author":"Juurlink","year":"2006"},{"issue":"2","key":"10.1016\/j.chest.2022.12.033_bib15","first-page":"67","article-title":"Coding accuracy of administrative drug claims in the Ontario Drug Benefit database","volume":"10","author":"Levy","year":"2003","journal-title":"Can J Clin Pharmacol"},{"key":"10.1016\/j.chest.2022.12.033_bib16","series-title":"Patterns of Health Care in Ontario","year":"1994"},{"issue":"3","key":"10.1016\/j.chest.2022.12.033_bib17","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/1475-6773.00047","article-title":"Agreement between self-reported and routinely collected health-care utilization data among seniors","volume":"37","author":"Raina","year":"2002","journal-title":"Health Services Res"},{"key":"10.1016\/j.chest.2022.12.033_bib18","series-title":"Patterns of Health Care in Ontario: the ICES Practice Atlas","first-page":"339","article-title":"Appendix I: a summary of studies on the quality of health care administrative databases in Canada","author":"Williams","year":"2000"},{"issue":"3","key":"10.1016\/j.chest.2022.12.033_bib19","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1097\/MLR.0b013e318245a754","article-title":"The accuracy of administrative data for identifying the presence and timing of admission to intensive care units in a Canadian province","volume":"50","author":"Garland","year":"2012","journal-title":"Med Care"},{"issue":"8","key":"10.1016\/j.chest.2022.12.033_bib20","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/j.jclinepi.2005.11.015","article-title":"Administrative data accurately identified intensive care unit admissions in Ontario","volume":"59","author":"Scales","year":"2006","journal-title":"J\u00a0Clin Epidemiol"},{"issue":"4","key":"10.1016\/j.chest.2022.12.033_bib21","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1164\/rccm.201912-2503OC","article-title":"New opioid use after invasive mechanical ventilation and hospital discharge","volume":"202","author":"Wunsch","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"10.1016\/j.chest.2022.12.033_bib22","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1001\/jama.288.4.462","article-title":"Adherence with statin therapy in elderly patients with and without acute coronary syndromes","volume":"288","author":"Jackevicius","year":"2002","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.chest.2022.12.033_bib23","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0232707","article-title":"Statin discontinuation and new antipsychotic use after an acute hospital stay vary by hospital","volume":"15","author":"Coe","year":"2020","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.chest.2022.12.033_bib24","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/0895-4356(92)90133-8","article-title":"Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases","volume":"45","author":"Deyo","year":"1992","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.chest.2022.12.033_bib25","series-title":"Development and Evaluation of the Johns Hopkins University risk Adjustment Models for Medicare+Choice Plan Payment","author":"Abrams","year":"2003"},{"issue":"4","key":"10.1016\/j.chest.2022.12.033_bib26","article-title":"Factors associated with polypharmacy and excessive polypharmacy in older people with intellectual disability differ from the general population: a cross-sectional observational nationwide study","volume":"6","author":"O\u2019Dwyer","year":"2016","journal-title":"BMJ Open"},{"issue":"6","key":"10.1016\/j.chest.2022.12.033_bib27","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1080\/03610910902859574","article-title":"Using the standardized difference to compare the prevalence of a binary variable between two groups in observational research","volume":"38","author":"Austin","year":"2009","journal-title":"Commun Stat-Simul C"},{"key":"10.1016\/j.chest.2022.12.033_bib28","series-title":"Clinical Handbook of Psychotropic Drugs","year":"2021"},{"issue":"20","key":"10.1016\/j.chest.2022.12.033_bib29","doi-asserted-by":"crossref","first-page":"3257","DOI":"10.1002\/sim.7336","article-title":"Intermediate and advanced topics in multilevel logistic regression analysis","volume":"36","author":"Austin","year":"2017","journal-title":"Stat Med"},{"issue":"16","key":"10.1016\/j.chest.2022.12.033_bib30","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1080\/00949655.2018.1504945","article-title":"The effect of number of clusters and cluster size on statistical power and type I error rates when testing random effects variance components in multilevel linear and logistic regression models","volume":"88","author":"Austin","year":"2018","journal-title":"J\u00a0Stat Comput Simul"},{"issue":"4","key":"10.1016\/j.chest.2022.12.033_bib31","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1136\/jech.2004.029454","article-title":"A\u00a0brief conceptual tutorial of multilevel analysis in social epidemiology: using measures of clustering in multilevel logistic regression to investigate contextual phenomena","volume":"60","author":"Merlo","year":"2006","journal-title":"J\u00a0Epidemiol Community Health"},{"issue":"27","key":"10.1016\/j.chest.2022.12.033_bib32","doi-asserted-by":"crossref","first-page":"4391","DOI":"10.1002\/sim.7501","article-title":"Practical recommendations for reporting Fine-Gray model analyses for competing risk data","volume":"36","author":"Austin","year":"2017","journal-title":"Stat Med"},{"issue":"9","key":"10.1016\/j.chest.2022.12.033_bib33","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1002\/sim.4780140936","article-title":"Modelling Survival Data in Medical Research. D. Collett, Chapman & Hall, London, 1994. No of pages: XVII\u00a0+ 347","volume":"14","author":"Van Houwelingen","year":"1995","journal-title":"Stat Med"},{"issue":"10","key":"10.1016\/j.chest.2022.12.033_bib34","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1097\/CCM.0000000000001196","article-title":"Recall of ICU stay in patients managed with a sedation protocol or a sedation protocol with daily interruption","volume":"43","author":"Burry","year":"2015","journal-title":"Crit Care Med"},{"issue":"14","key":"10.1016\/j.chest.2022.12.033_bib35","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1056\/NEJMoa1301372","article-title":"Long-term cognitive impairment after critical illness","volume":"369","author":"Pandharipande","year":"2013","journal-title":"N\u00a0Engl J Med"},{"issue":"11","key":"10.1016\/j.chest.2022.12.033_bib36","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1007\/s00134-019-05752-5","article-title":"Mental illness after admission to an intensive care unit","volume":"45","author":"Sivanathan","year":"2019","journal-title":"Intensive Care Med"},{"issue":"11","key":"10.1016\/j.chest.2022.12.033_bib37","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1001\/jama.2014.2137","article-title":"Psychiatric diagnoses and psychoactive medication use among nonsurgical critically ill patients receiving mechanical ventilation","volume":"311","author":"Wunsch","year":"2014","journal-title":"JAMA"},{"issue":"8","key":"10.1016\/j.chest.2022.12.033_bib38","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1001\/jama.2010.167","article-title":"Association between acute care and critical illness hospitalization and cognitive function in older adults","volume":"303","author":"Ehlenbach","year":"2010","journal-title":"JAMA"},{"issue":"16","key":"10.1016\/j.chest.2022.12.033_bib39","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1001\/jama.2010.1553","article-title":"Long-term cognitive impairment and functional disability among survivors of severe sepsis","volume":"304","author":"Iwashyna","year":"2010","journal-title":"JAMA"},{"issue":"15","key":"10.1016\/j.chest.2022.12.033_bib40","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.2146\/ajhp140533","article-title":"Postintensive care syndrome and the role of a follow-up clinic","volume":"72","author":"Stollings","year":"2015","journal-title":"Am J Health Syst Pharm"},{"issue":"2","key":"10.1016\/j.chest.2022.12.033_bib41","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1097\/CCM.0b013e318232da75","article-title":"Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference","volume":"40","author":"Needham","year":"2012","journal-title":"Crit Care Med"},{"key":"10.1016\/j.chest.2022.12.033_bib42","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jcrc.2018.02.011","article-title":"Comprehensive care of ICU survivors: development and implementation of an ICU recovery center","volume":"46","author":"Sevin","year":"2018","journal-title":"J\u00a0Crit Care"},{"issue":"5","key":"10.1016\/j.chest.2022.12.033_bib43","first-page":"339","article-title":"Deprescribing benzodiazepine receptor agonists: evidence-based clinical practice guideline","volume":"64","author":"Pottie","year":"2018","journal-title":"Can Fam Physician"},{"issue":"1","key":"10.1016\/j.chest.2022.12.033_bib44","doi-asserted-by":"crossref","first-page":"116","DOI":"10.5770\/cgj.23.419","article-title":"Canadian guidelines on benzodiazepine receptor agonist use disorder among older\u00a0adults","volume":"23","author":"Conn","year":"2020","journal-title":"Can Geriatrics J"},{"issue":"8","key":"10.1016\/j.chest.2022.12.033_bib45","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1111\/jgs.15418","article-title":"Longitudinal trends and variation in antipsychotic use in older adults after cardiac surgery","volume":"66","author":"Kim","year":"2018","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"2","key":"10.1016\/j.chest.2022.12.033_bib46","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1097\/01.CCM.0000300275.63811.B3","article-title":"Impact of a clinical pharmacist-enforced intensive care unit sedation protocol on duration of mechanical ventilation and hospital stay","volume":"36","author":"Marshall","year":"2008","journal-title":"Crit Care Med"},{"issue":"4","key":"10.1016\/j.chest.2022.12.033_bib47","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jcrc.2003.10.001","article-title":"Medication reconciliation: a practical tool to reduce the risk of medication errors","volume":"18","author":"Pronovost","year":"2003","journal-title":"J\u00a0Crit Care"},{"issue":"18","key":"10.1016\/j.chest.2022.12.033_bib48","doi-asserted-by":"crossref","first-page":"1889","DOI":"10.1001\/jama.2018.16131","article-title":"Effect of a pharmacist-led educational intervention on inappropriate medication prescriptions in older adults","volume":"320","author":"Martin","year":"2018","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.chest.2022.12.033_bib49","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/jhm.1921","article-title":"Nurse-pharmacist collaboration on medication reconciliation prevents potential harm","volume":"7","author":"Feldman","year":"2012","journal-title":"J\u00a0Hosp Med"},{"issue":"3","key":"10.1016\/j.chest.2022.12.033_bib50","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1177\/0897190012465987","article-title":"Evaluation of discontinuation of atypical antipsychotics prescribed for ICU delirium","volume":"26","author":"Jasiak","year":"2013","journal-title":"J\u00a0Pharm Pract"},{"issue":"2","key":"10.1016\/j.chest.2022.12.033_bib51","doi-asserted-by":"crossref","first-page":"88","DOI":"10.9740\/mhc.2019.03.088","article-title":"Rates of new antipsychotic prescriptions and continuation at discharge from a medical unit in a community teaching hospital serving rural counties","volume":"9","author":"Phan","year":"2019","journal-title":"Ment Health Clin"},{"issue":"1","key":"10.1016\/j.chest.2022.12.033_bib52","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-016-1557-1","article-title":"Antipsychotic prescribing patterns during and after critical illness: a prospective cohort study","volume":"20","author":"Tomichek","year":"2016","journal-title":"Critical Care"}],"container-title":["CHEST"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369223000119?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369223000119?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T17:41:40Z","timestamp":1727286100000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369223000119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":51,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["S0012369223000119"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2022.12.033","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"New and Persistent Sedative Prescriptions Among Older Adults Following a Critical Illness","name":"articletitle","label":"Article Title"},{"value":"CHEST","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2022.12.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}