{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T15:40:28Z","timestamp":1792597228815,"version":"4.5.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T00:00:00Z","timestamp":1730937600000},"content-version":"am","delay-in-days":372,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.chest.2023.06.039","type":"journal-article","created":{"date-parts":[[2023,7,5]],"date-time":"2023-07-05T20:51:47Z","timestamp":1688590307000},"page":"1097-1107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["Improving Diagnosis of Pulmonary Mucormycosis"],"prefix":"10.1016","volume":"164","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9596-662X","authenticated-orcid":false,"given":"Anne","family":"Coste","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Conrad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rapha\u00ebl","family":"Porcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain","family":"Poir\u00e9e","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Peterlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Defrance","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Letscher-Bru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent","family":"Morio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Gastinne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Elisabeth","family":"Bougnoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Suarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Nevez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damien","family":"Dupont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Ader","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carine","family":"Halfon-Domenech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Ducastelle-Lepr\u00eatre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Botterel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Millon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaelle","family":"Guillerm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9verine","family":"Ansart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Boutoille","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Pierre","family":"Ledoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Etienne","family":"Herbrecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Robin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Melica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Danion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Blanchard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Paccoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dea","family":"Garcia-Hermoso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Lortholary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raoul","family":"Herbrecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Lanternier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Freymond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agathe","family":"S\u00e9n\u00e9chal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amine","family":"Belhabri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Menotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Persat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.chest.2023.06.039_bib1","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.3201\/eid2007.140087","article-title":"Population-based analysis of invasive fungal infections, France, 2001-2010","volume":"20","author":"Bitar","year":"2014","journal-title":"Emerging Infect Dis"},{"issue":"9","key":"10.1016\/j.chest.2023.06.039_bib2","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.3201\/eid1609.100276","article-title":"Increasing incidence of mucormycosis in University Hospital, Belgium","volume":"16","author":"Saegeman","year":"2010","journal-title":"Emerging Infect Dis"},{"issue":"3","key":"10.1016\/j.chest.2023.06.039_bib3","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1111\/myc.13418","article-title":"Increasing incidence of mucormycosis in Spanish inpatients from 1997 to 2018","volume":"65","author":"Parra Fari\u00f1as","year":"2022","journal-title":"Mycoses"},{"issue":"9","key":"10.1016\/j.chest.2023.06.039_bib4","doi-asserted-by":"crossref","first-page":"e240","DOI":"10.1016\/S1473-3099(22)00124-4","article-title":"Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis: Delphi consensus statement from the Fungal Infection Study Forum and Academy of Pulmonary Sciences, India","volume":"22","author":"Muthu","year":"2022","journal-title":"Lancet Infect Dis"},{"issue":"suppl 1","key":"10.1016\/j.chest.2023.06.039_bib5","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1093\/cid\/cir880","article-title":"A global analysis of mucormycosis in France: the RetroZygo Study (2005-2007)","volume":"54","author":"Lanternier","year":"2012","journal-title":"Clin Infect Dis"},{"issue":"12","key":"10.1016\/j.chest.2023.06.039_bib6","doi-asserted-by":"crossref","first-page":"1859","DOI":"10.1111\/j.1469-0691.2010.03456.x","article-title":"Zygomycosis in Europe: analysis of 230 cases accrued by the registry of the European Confederation of Medical Mycology (ECMM) Working Group on Zygomycosis between 2005 and 2007","volume":"17","author":"Skiada","year":"2011","journal-title":"Clin Microbiol Infect"},{"issue":"9","key":"10.1016\/j.chest.2023.06.039_bib7","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1111\/j.1600-6143.2009.02754.x","article-title":"Pulmonary zygomycosis in solid organ transplant recipients in the current era","volume":"9","author":"Sun","year":"2009","journal-title":"Am J Transplant"},{"issue":"4","key":"10.1016\/j.chest.2023.06.039_bib8","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.cmi.2020.12.035","article-title":"Has the mortality from pulmonary mucormycosis changed over time? A systematic review and meta-analysis","volume":"27","author":"Muthu","year":"2021","journal-title":"Clin Microbiol Infect"},{"issue":"6","key":"10.1016\/j.chest.2023.06.039_bib9","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1093\/cid\/ciz1008","article-title":"Revision and update of the consensus definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium","volume":"71","author":"Donnelly","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"12","key":"10.1016\/j.chest.2023.06.039_bib10","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1111\/myc.12428","article-title":"Delaying diagnostic procedure significantly increases mortality in patients with invasive mucormycosis","volume":"58","author":"Jeong","year":"2015","journal-title":"Mycoses"},{"issue":"1","key":"10.1016\/j.chest.2023.06.039_bib11","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/myc.12101","article-title":"Risk factors for early mortality in haematological malignancy patients with pulmonary mucormycosis","volume":"57","author":"Lewis","year":"2014","journal-title":"Mycoses"},{"issue":"5","key":"10.1016\/j.chest.2023.06.039_bib12","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1093\/cid\/ciab1066","article-title":"Evaluation of serum Mucorales PCR for the diagnosis of mucormycoses: the MODIMUCOR prospective trial","volume":"75","author":"Millon","year":"2022","journal-title":"Clin Infect Dis"},{"issue":"12","key":"10.1016\/j.chest.2023.06.039_bib13","doi-asserted-by":"crossref","first-page":"e405","DOI":"10.1016\/S1473-3099(19)30312-3","article-title":"Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium","volume":"19","author":"Cornely","year":"2019","journal-title":"Lancet Infect Dis"},{"issue":"suppl 2","key":"10.1016\/j.chest.2023.06.039_bib14","doi-asserted-by":"crossref","first-page":"S79","DOI":"10.1093\/cid\/ciaa1855","article-title":"Guidance on imaging for invasive pulmonary aspergillosis and mucormycosis: from the Imaging Working Group for the Revision and Update of the Consensus Definitions of Fungal Disease from the EORTC\/MSGERC","volume":"72","author":"Alexander","year":"2021","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.chest.2023.06.039_bib15","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/mmy\/myx017","article-title":"Diabetes mellitus as the major risk factor for mucormycosis in Mexico: epidemiology, diagnosis, and outcomes of reported cases","volume":"56","author":"Corzo-Le\u00f3n","year":"2018","journal-title":"Med Mycol"},{"issue":"4","key":"10.1016\/j.chest.2023.06.039_bib16","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1093\/mmy\/myy060","article-title":"A prospective multicenter study on mucormycosis in India: epidemiology, diagnosis, and treatment","volume":"57","author":"Prakash","year":"2019","journal-title":"Med Mycol"},{"issue":"1","key":"10.1016\/j.chest.2023.06.039_bib17","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cmi.2018.07.011","article-title":"The epidemiology and clinical manifestations of mucormycosis: a systematic review and meta-analysis of case reports","volume":"25","author":"Jeong","year":"2019","journal-title":"Clin Microbiol Infect"},{"issue":"6","key":"10.1016\/j.chest.2023.06.039_bib18","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1086\/605445","article-title":"Zygomycosis in solid organ transplant recipients: a prospective, matched case-control study to assess risks for disease and outcome","volume":"200","author":"Singh","year":"2009","journal-title":"J Infect Dis"},{"issue":"1","key":"10.1016\/j.chest.2023.06.039_bib19","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1186\/s12879-016-2023-z","article-title":"Prevalence, clinical and economic burden of mucormycosis-related hospitalizations in the United States: a retrospective study","volume":"16","author":"Kontoyiannis","year":"2016","journal-title":"BMC Infect Dis"},{"issue":"5","key":"10.1016\/j.chest.2023.06.039_bib20","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1086\/432579","article-title":"Epidemiology and outcome of zygomycosis: a review of 929 reported cases","volume":"41","author":"Roden","year":"2005","journal-title":"Clin Infect Dis"},{"issue":"10","key":"10.1016\/j.chest.2023.06.039_bib21","doi-asserted-by":"crossref","first-page":"E396","DOI":"10.1111\/j.1469-0691.2012.03908.x","article-title":"Mucormycosis after allogeneic haematopoietic stem cell transplantation: a French Multicentre Cohort Study (2003-2008)","volume":"18","author":"Xhaard","year":"2012","journal-title":"Clin Microbiol Infect"},{"issue":"1","key":"10.1016\/j.chest.2023.06.039_bib22","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1186\/s12879-017-2381-1","article-title":"Mucormycosis in renal transplant recipients: review of 174 reported cases","volume":"17","author":"Song","year":"2017","journal-title":"BMC Infect Dis"},{"issue":"4","key":"10.1016\/j.chest.2023.06.039_bib23","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1086\/510592","article-title":"Invasive aspergillosis following hematopoietic cell transplantation: outcomes and prognostic factors associated with mortality","volume":"44","author":"Upton","year":"2007","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.chest.2023.06.039_bib24","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1086\/318483","article-title":"Aspergillosis case-fatality rate: systematic review of the literature","volume":"32","author":"Lin","year":"2001","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.chest.2023.06.039_bib25","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1086\/515116","article-title":"Survival and prognostic factors of invasive aspergillosis after allogeneic bone marrow transplantation","volume":"28","author":"Ribaud","year":"1999","journal-title":"Clin Infect Dis"},{"issue":"8","key":"10.1016\/j.chest.2023.06.039_bib26","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1111\/myc.12624","article-title":"Prevalence of the reversed halo sign in neutropenic patients compared with non-neutropenic patients: data from a single-centre study involving 27 patients with pulmonary mucormycosis (2003-2016)","volume":"60","author":"Bourcier","year":"2017","journal-title":"Mycoses"},{"issue":"5","key":"10.1016\/j.chest.2023.06.039_bib27","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1093\/cid\/cit929","article-title":"The reversed halo sign: pathognomonic pattern of pulmonary mucormycosis in leukemic patients with neutropenia?","volume":"58","author":"Legouge","year":"2014","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.chest.2023.06.039_bib28","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1007\/s00330-017-5007-5","article-title":"Pulmonary mucormycosis: serial morphologic changes on computed tomography correlate with clinical and pathologic findings","volume":"28","author":"Nam","year":"2018","journal-title":"Eur Radiol"},{"issue":"8","key":"10.1016\/j.chest.2023.06.039_bib29","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1182\/blood-2011-04-351601","article-title":"The strategy for the diagnosis of invasive pulmonary aspergillosis should depend on both the underlying condition and the leukocyte count of patients with hematologic malignancies","volume":"119","author":"Bergeron","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.chest.2023.06.039_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejrad.2020.109042","article-title":"CT of invasive pulmonary aspergillosis (IPA) in cases with hematologic malignancy: comparison of CT features in the group classified by the severity of neutropenia and underlying disease","volume":"131","author":"Yanagawa","year":"2020","journal-title":"Eur J Radiol"},{"issue":"12","key":"10.1016\/j.chest.2023.06.039_bib31","first-page":"1405","article-title":"Utility of percutaneous lung biopsy for diagnosing filamentous fungal infections in hematologic malignancies","volume":"88","author":"Nosari","year":"2003","journal-title":"Haematologica"},{"issue":"7","key":"10.1016\/j.chest.2023.06.039_bib32","doi-asserted-by":"crossref","first-page":"711","DOI":"10.3390\/jof8070711","article-title":"COVID-19-associated pulmonary mucormycosis","volume":"8","author":"Krishna","year":"2022","journal-title":"J Fungi (Basel)"}],"container-title":["CHEST"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369223009467?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369223009467?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T08:51:02Z","timestamp":1757926262000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369223009467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S0012369223009467"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2023.06.039","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Improving Diagnosis of Pulmonary Mucormycosis","name":"articletitle","label":"Article Title"},{"value":"CHEST","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2023.06.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}