{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:22:37Z","timestamp":1790623357517,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T00:00:00Z","timestamp":1691452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/igo\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","journal.chestnet.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["CHEST"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.chest.2023.08.003","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T04:08:00Z","timestamp":1691640480000},"page":"213-223","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":52,"title":["Association of Metabolic Syndrome With Risk of Lung Cancer"],"prefix":"10.1016","volume":"165","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6630-7468","authenticated-orcid":false,"given":"Mengmeng","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Mei","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niki","family":"Dimou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7632-3648","authenticated-orcid":false,"given":"Ji-Bin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.chest.2023.08.003_bib2","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1056\/NEJMoa1211776","article-title":"Selection criteria for lung cancer screening","volume":"368","author":"Tammem\u00e4gi","year":"2013","journal-title":"N\u00a0Engl J Med"},{"issue":"2","key":"10.1016\/j.chest.2023.08.003_bib3","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1136\/thoraxjnl-2020-215158","article-title":"Liverpool Lung Project lung cancer risk stratification model: calibration and prospective validation","volume":"76","author":"Field","year":"2021","journal-title":"Thorax"},{"issue":"10","key":"10.1016\/j.chest.2023.08.003_bib4","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1001\/jama.2021.1117","article-title":"Screening for lung cancer: US Preventive Services Task Force Recommendation Statement","volume":"325","author":"Krist","year":"2021","journal-title":"JAMA"},{"issue":"12","key":"10.1016\/j.chest.2023.08.003_bib5","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1038\/s41416-021-01278-0","article-title":"Comparative performance of lung cancer risk models to define lung screening eligibility in the United Kingdom","volume":"124","author":"Robbins","year":"2021","journal-title":"Br J Cancer"},{"issue":"16","key":"10.1016\/j.chest.2023.08.003_bib6","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","volume":"120","author":"Alberti","year":"2009","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.chest.2023.08.003_bib7","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1161\/ATVBAHA.107.151092","article-title":"Metabolic syndrome pandemic","volume":"28","author":"Grundy","year":"2008","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"24","key":"10.1016\/j.chest.2023.08.003_bib8","doi-asserted-by":"crossref","first-page":"2526","DOI":"10.1001\/jama.2020.4501","article-title":"Trends in the prevalence of metabolic syndrome in the United States, 2011-2016","volume":"323","author":"Hirode","year":"2020","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.chest.2023.08.003_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/obr.12229","article-title":"Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies","volume":"16","author":"O\u2019Neill","year":"2015","journal-title":"Obes Rev"},{"issue":"11","key":"10.1016\/j.chest.2023.08.003_bib10","doi-asserted-by":"crossref","first-page":"2402","DOI":"10.2337\/dc12-0336","article-title":"Metabolic syndrome and risk of cancer: a systematic review and meta-analysis","volume":"35","author":"Esposito","year":"2012","journal-title":"Diabetes Care"},{"issue":"3","key":"10.1016\/j.chest.2023.08.003_bib11","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1159\/000443743","article-title":"Association between metabolic syndrome and cancer","volume":"68","author":"Uzunlulu","year":"2016","journal-title":"Ann Nutr Metab"},{"issue":"3","key":"10.1016\/j.chest.2023.08.003_bib12","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0264634","article-title":"Association between metabolic syndrome and 13 types of cancer in Catalonia: a matched case-control study","volume":"17","author":"L\u00f3pez-Jim\u00e9nez","year":"2022","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.chest.2023.08.003_bib13","doi-asserted-by":"crossref","first-page":"dgaa596","DOI":"10.1210\/clinem\/dgaa596","article-title":"Metabolic syndrome and risk of lung cancer: an analysis of Korean national health insurance corporation database","volume":"105","author":"Sin","year":"2020","journal-title":"J\u00a0Clin Endocrinol Metab"},{"key":"10.1016\/j.chest.2023.08.003_bib14","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s13098-020-00598-0","article-title":"Metabolic syndrome and the incidence of lung cancer: a meta-analysis of cohort studies","volume":"12","author":"Qiao","year":"2020","journal-title":"Diabetol Metab Syndr"},{"issue":"3","key":"10.1016\/j.chest.2023.08.003_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001779","article-title":"UK Biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age","volume":"12","author":"Sudlow","year":"2015","journal-title":"PLoS Med"},{"issue":"11","key":"10.1016\/j.chest.2023.08.003_bib16","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1111\/j.1464-5491.2012.03762.x","article-title":"Use of HbA1c in the diagnosis of diabetes mellitus in the UK. The implementation of World Health Organization guidance 2011","volume":"29","author":"John","year":"2012","journal-title":"Diabet Med"},{"issue":"4","key":"10.1016\/j.chest.2023.08.003_bib17","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/ijc.33255","article-title":"Metabolic syndrome biomarkers and prostate cancer risk in the UK Biobank","volume":"148","author":"Monroy-Iglesias","year":"2021","journal-title":"Int J Cancer"},{"issue":"10","key":"10.1016\/j.chest.2023.08.003_bib18","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1002\/ijc.32576","article-title":"Blood pressure and risk of cancer in the European Prospective Investigation into Cancer and Nutrition","volume":"146","author":"Christakoudi","year":"2020","journal-title":"Int J Cancer"},{"issue":"9","key":"10.1016\/j.chest.2023.08.003_bib19","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1097\/JTO.0000000000000630","article-title":"The 2015 World Health Organization Classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification","volume":"10","author":"Travis","year":"2015","journal-title":"J\u00a0Thorac Oncol"},{"issue":"9","key":"10.1016\/j.chest.2023.08.003_bib20","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1002\/ijc.34167","article-title":"The influence of postscreening follow-up time and participant characteristics on estimates of overdiagnosis from lung cancer screening trials","volume":"151","author":"Li","year":"2022","journal-title":"Int J Cancer"},{"issue":"11","key":"10.1016\/j.chest.2023.08.003_bib21","doi-asserted-by":"crossref","first-page":"e478","DOI":"10.1016\/S2542-5196(19)30214-1","article-title":"Environmental correlates of chronic obstructive pulmonary disease in 96 779 participants from the UK Biobank: a cross-sectional, observational study","volume":"3","author":"Sarkar","year":"2019","journal-title":"Lancet Planet Health"},{"key":"10.1016\/j.chest.2023.08.003_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclepro.2020.123931","article-title":"Nonlinear and lagged meteorological effects on daily levels of ambient PM2.5 and O3: evidence from 284 Chinese cities","volume":"278","author":"Yang","year":"2021","journal-title":"J\u00a0Clean Prod"},{"key":"10.1016\/j.chest.2023.08.003_bib23","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/745742","article-title":"smoothHR: an R package for pointwise nonparametric estimation of hazard ratio curves of continuous predictors","volume":"2013","author":"Meira-Machado","year":"2013","journal-title":"Comput Math Methods Med"},{"issue":"7","key":"10.1016\/j.chest.2023.08.003_bib24","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1136\/heartjnl-2021-319238","article-title":"Cross-sectional analysis of educational inequalities in primary prevention statin use in UK Biobank","volume":"108","author":"Carter","year":"2022","journal-title":"Heart"},{"issue":"3","key":"10.1016\/j.chest.2023.08.003_bib25","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1093\/ije\/dyab265","article-title":"Glycated haemoglobin measurements from UK Biobank are different to those in linked primary care records: implications for combining biochemistry data from research studies and routine clinical care","volume":"51","author":"Young","year":"2022","journal-title":"Int J Epidemiol"},{"issue":"3","key":"10.1016\/j.chest.2023.08.003_bib26","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3961\/jpmph.16.021","article-title":"Metabolic risk profile and cancer in Korean men and women","volume":"49","author":"Ko","year":"2016","journal-title":"J\u00a0Prev Med Public Health"},{"issue":"2","key":"10.1016\/j.chest.2023.08.003_bib27","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.metabol.2014.10.008","article-title":"Metabolic syndrome and risk of cancer: which link?","volume":"64","author":"Mendon\u00e7a","year":"2015","journal-title":"Metabolism"},{"issue":"6","key":"10.1016\/j.chest.2023.08.003_bib28","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.3945\/ajcn.115.124321","article-title":"Lipid biomarkers and long-term risk of cancer in the Women\u2019s Health Study","volume":"103","author":"Chandler","year":"2016","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"10.1016\/j.chest.2023.08.003_bib29","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1186\/s13045-020-00963-6","article-title":"Low high-density lipoprotein and increased risk of several cancers: 2 population-based cohort studies including 116,728 individuals","volume":"13","author":"Pedersen","year":"2020","journal-title":"J\u00a0Hematol Oncol"},{"issue":"4","key":"10.1016\/j.chest.2023.08.003_bib30","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.jacl.2017.05.004","article-title":"Blood lipids profile and lung cancer risk in a meta-analysis of prospective cohort studies","volume":"11","author":"Lin","year":"2017","journal-title":"J\u00a0Clin Lipidol"},{"issue":"12","key":"10.1016\/j.chest.2023.08.003_bib31","doi-asserted-by":"crossref","first-page":"2972","DOI":"10.1002\/ijc.32051","article-title":"Independent and joint associations of blood lipids and lipoproteins with lung cancer risk in Chinese males: a prospective cohort study","volume":"144","author":"Lyu","year":"2019","journal-title":"Int J Cancer"},{"issue":"1","key":"10.1016\/j.chest.2023.08.003_bib32","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1186\/s12944-018-0925-z","article-title":"Dyslipidemia and non-small cell lung cancer risk in Chinese population: a case-control study","volume":"17","author":"Hao","year":"2018","journal-title":"Lipids Health Dis"},{"issue":"8","key":"10.1016\/j.chest.2023.08.003_bib33","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1093\/jnci\/djx286","article-title":"Overall and central obesity and risk of lung cancer: a pooled analysis","volume":"110","author":"Yu","year":"2018","journal-title":"J\u00a0Natl Cancer Inst"},{"issue":"8","key":"10.1016\/j.chest.2023.08.003_bib34","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1038\/s41416-018-0214-7","article-title":"Waist circumference and risk of 23 site-specific cancers: a population-based cohort study of Korean adults","volume":"119","author":"Lee","year":"2018","journal-title":"Br J Cancer"},{"issue":"5","key":"10.1016\/j.chest.2023.08.003_bib35","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1002\/ijc.27719","article-title":"Obesity and incidence of lung cancer: a meta-analysis","volume":"132","author":"Yang","year":"2013","journal-title":"Int J Cancer"},{"issue":"1","key":"10.1016\/j.chest.2023.08.003_bib36","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s12916-020-01877-3","article-title":"Body mass index and waist circumference in relation to the risk of 26 types of cancer: a prospective cohort study of 3.5 million adults in Spain","volume":"19","author":"Recalde","year":"2021","journal-title":"BMC Med"},{"issue":"12","key":"10.1016\/j.chest.2023.08.003_bib37","doi-asserted-by":"crossref","first-page":"810","DOI":"10.3390\/nu8120810","article-title":"Abdominal obesity and lung cancer risk: systematic review and meta-analysis of prospective studies","volume":"8","author":"Hidayat","year":"2016","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.chest.2023.08.003_bib38","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1038\/s41467-018-08159-w","article-title":"Central body fatness is a stronger predictor of cancer risk than overall body size","volume":"10","author":"Barberio","year":"2019","journal-title":"Nat Commun"},{"issue":"12","key":"10.1016\/j.chest.2023.08.003_bib39","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s10654-019-00587-2","article-title":"Predicted lean body mass, fat mass and risk of lung cancer: prospective US cohort study","volume":"34","author":"Jeong","year":"2019","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.chest.2023.08.003_bib40","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.3389\/fonc.2019.01215","article-title":"The metabolic landscape of lung cancer: new insights in a disturbed glucose metabolism","volume":"9","author":"Vanhove","year":"2019","journal-title":"Front Oncol"},{"issue":"10","key":"10.1016\/j.chest.2023.08.003_bib41","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1158\/1055-9965.EPI-17-0293","article-title":"Serum insulin, glucose, indices of insulin resistance, and risk of lung cancer","volume":"26","author":"Argirion","year":"2017","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"10","key":"10.1016\/j.chest.2023.08.003_bib42","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1016\/j.ejca.2013.02.025","article-title":"Diabetes mellitus as an independent risk factor for lung cancer: a meta-analysis of observational studies","volume":"49","author":"Lee","year":"2013","journal-title":"Eur J Cancer"},{"issue":"9","key":"10.1016\/j.chest.2023.08.003_bib43","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1038\/bjc.2014.150","article-title":"Does cancer risk increase with HbA1c, independent of diabetes?","volume":"110","author":"de Beer","year":"2014","journal-title":"Br J Cancer"},{"issue":"7","key":"10.1016\/j.chest.2023.08.003_bib44","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1002\/ijc.29917","article-title":"High hemoglobin A1c levels within the non-diabetic range are associated with the risk of all cancers","volume":"138","author":"Goto","year":"2016","journal-title":"Int J Cancer"},{"issue":"7","key":"10.1016\/j.chest.2023.08.003_bib45","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.22070","article-title":"Sex differences in the progression of metabolic risk factors in diabetes development","volume":"5","author":"Yoshida","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"19","key":"10.1016\/j.chest.2023.08.003_bib46","doi-asserted-by":"crossref","first-page":"2098","DOI":"10.1177\/15353702211019697","article-title":"Role of sex hormones in lung cancer","volume":"246","author":"Fuentes","year":"2021","journal-title":"Exp Biol Med (Maywood)"}],"container-title":["CHEST"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369223052637?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0012369223052637?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,7]],"date-time":"2024-05-07T21:07:42Z","timestamp":1715116062000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0012369223052637"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["S0012369223052637"],"URL":"https:\/\/doi.org\/10.1016\/j.chest.2023.08.003","relation":{},"ISSN":["0012-3692"],"issn-type":[{"value":"0012-3692","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of Metabolic Syndrome With Risk of Lung Cancer","name":"articletitle","label":"Article Title"},{"value":"CHEST","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.chest.2023.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier Inc under license from the American College of Chest Physicians.","name":"copyright","label":"Copyright"}]}}